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Radio-Frequency device designed for palliative treatments of patient with painful metastatic bone tumors involving vertebral bodies, sacrum, iliac crest and peri-acetabulum

SPINERY

Stefano Marini, Dr.

Luigi Manfré, Prof.

Francesca Amato, Dr.

Francesco Amato, Dr.

Mario Muto, Prof

Matteo Bellini, Dr

Matteo Bellini, Dr.

SPINERY is a Radiofrequency (RF) device designed for palliative treatment of patients with painful metastatic bone tumors involving vertebral bodies, sacrum, iliac crest and peri-acetabulum.

In particular, SPINERY is conceived for pain reduction in patients affected by metastatic bone tumors involving the vertebral bodies, sacrum, iliac crest and periacetabulum, in patients with indication for Standard Therapy and in patients who have failed, not candidates or refuse Standard Therapy.

Primary objective of the SPARTA Study is to demonstrate that SPINERY RF device is effective in short-term (3 months) pain reduction in patients affected by metastatic bone tumors and to demonstrate that SPINERY RF device is safe in the RF ablation treatment of metastatic bone tumors, without causing device-related adverse events including, in particular, nerve injury.

Primary objective hypothesis will be obtained with Brief Pain Inventory (BPI) scale performance questionnaire in terms of palliative treatment.

Change of Worst Pain Score expressed as average reduction of 2 BPI (Brief Pain Inventory) scores will be calculated as:

μc = worst-pain 3-month - worst-pain baseline

A negative average value for change in pain represents a lowering of the subject's pain score (an improvement, or reduction in pain) and a positive value represents an increase in the subject's pain score (a worsening or increase in pain). Worst pain score at the target treatment site will be collected from the BPI in the past 24 hours.

Prospective, Multicenter, no control group

SPINERY™ A Novel Radio-Frequency Tumor Ablation Device Study

Clinical Study of SPINERY™ A Novel Radio-Frequency Tumor Ablation Device for Spine Metastatic Tumors

Change of Worst Pain Score expressed as average reduction of 2 BPI scores: Thoracic/Lumbar/ Peri-acetabulum/Iliac Crest/Sacrum RF Ablation

Completion (%) of the ablation procedure without device-related adverse events including in particular nerve injury

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
SPINERY™ A Novel Radio-Frequency Tumor Ablation Device Study	NCT05467540	Vertebral Metas...	SPINERY	18 Years -	Axon srl
SPINERY™ A Novel Radio-Frequency Tumor Ablation Device Study	NCT05467540	Vertebral Metas...	SPINERY	18 Years -	Axon srl

Spots Global Cancer Trial Database for spinery

Every month we try and update this database with for spinery cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for spinery

Every month we try and update this database with for spinery cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for spinery cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.