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Pancreatic Cancer

Three patients with advanced solid cancer will be subjected to repetitive hyperthermia starting with 2 hours (day 1), 4 hours (day 8) and 6 hours (day 15)

One patient with advanced solid cancer will receive 3 hyperthermia treatments of 4 hours per treatment. The next patient with advanced solid cancer will receive 3 hyperthermia treatments of 6 hours per treatment.

Three pancreatic cancer patients will be subjected to three hyperthermia treatments (2 hours duration per treatment) alone (1st treatment) or in combination with (2nd and 3rd treatment) Standard of Care (SOC) chemotherapy according to the NCCN guidelines.

Three pancreatic cancer patients will be subjected to three hyperthermia treatments (4 hours duration per treatment) alone (1st treatment) or in combination with (2nd and 3rd treatment) Standard of Care (SOC) chemotherapy according to the NCCN guidelines.

Three pancreatic cancer patients will be subjected to three hyperthermia treatments (6 hours duration per treatment) alone (1st treatment) or in combination with (2nd and 3rd treatment) Standard of Care (SOC) chemotherapy according to the NCCN guidelines.

Whole body hyperthermia to treat stage IV cancer patients

Whole body hyperthermia

Whole body hyperthermia to treat stage IV pancreatic cancer patients combined with standard of care chemotherapy

Standard of Care (SOC) chemotherapy according to the NCCN guidelines.

Oleg Rudenko, MD MSc

Marc Peeters, Professor

Dirk Ysebaert, Professor

Vera Saldien, Professor

Marc Peeters, MD PhD

Millions of patients die of cancer every year. There are several methods to treat cancer, including surgery, chemotherapy, radiotherapy and immunotherapy. Recently, hyperthermia therapy started playing a role in cancer therapy. It has shown effect in animal experiments and clinical practice. The sponsor has developed a novel device to use hyperthermia for advanced cancer. This study is to prove the safety in human patients of this device \& therapy and get the first data on efficacy.

Safety Study of Whole Body Hyperthermia for Advanced Cancer

A Mono-centric, First In-human (FIH), Safety and Preliminary Efficacy Study of (Neo)Adjuvant, Model-based, Whole-body Hyperthermia (WBHT) Treatment in Advanced Solid Cancer Patients or Stage IV (TxNxM1) Metastatic Pancreatic Adenocarcinoma Patients

The evolution of this clinically significant biological parameter will be measured compared to baseline

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Safety Study of Whole Body Hyperthermia for Advanced Cancer	NCT04467593	Advanced Cancer Pancreatic Canc...	Whole body hype... Standard of Car...	18 Years - 75 Years	ElmediX
Safety Study of Whole Body Hyperthermia for Advanced Cancer	NCT04467593	Advanced Cancer Pancreatic Canc...	Whole body hype... Standard of Car...	18 Years - 75 Years	ElmediX

Spots Global Cancer Trial Database for standard of care (soc) chemotherapy according to the nccn guidelines.