Symptoms and General Pathology

All Conditions

Neoplasms

Nutritional and Metabolic Diseases

Syndrome

Head and Neck Neoplasms

Refeeding Syndrome

Starvation

Malnutrition

Nutrition Disorders

Gastrointestinal Agents

All Drugs and Chemicals

Herbal and Botanical

Pancrelipase

Pancreatin

Cola

Consecutive admissions - n= 43 - 34 operated (79%) - 10 patients acutely admitted Diseases in Esophagus (8), gastric cavity (8), pancreas (7), colon/rectum (8), bile (4), small intestine (3), IBD (5) No interventions in the treatments, just observation

Consecutive admissions - n=8 - 7 radiation therapy - 1 operated Locations: 2 Larynx, 1 oro-pharynx, 4 tonsillar, 1 tung No interventions in the treatments, just observation

observation

jens R Andersen, MD, MPA

The incidence and main risk-factors analyzed in consecutive in-patients in the departments og gastroenterology and ear-nose and throat diseases (cancer in radiation therapy)

Patients with either parenteral- or tube feeding enter the study to assure sufficient nutrition.

During hospitalization patients were monitored with daily blood samples and clinical evaluation of symptoms in addition to the coverage of energy and protein in percent of estimated needs.

Refeeding phenomenon was defined as a decrease in plasma phosphate after the initiation of nutrition.

Refeeding syndrome as refeeding phenomenon and one or more relevant symptoms in addition (hypotension, cardiac arrhythmia, edema, confusion)

Incidence of Refeeding Syndrome in Consecutively Admitted Patients

Refeeding Syndrome - Incidence and Risk Factors: An Observational Study on Patients With G-I Disease and Head-neck Cancer

No. patients with decrease in plasma phosphate + clinical symptoms

No. patients with decrease in plasma phosphate after start of nutrition

St. Olavs Hospital

Jens Rikardt Andersen

Assoc Prof

Digestive System Diseases

Rare Diseases

Cholangiocarcinoma

Adenocarcinoma

Stomach Neoplasms

Esophageal Neoplasms

Gastrointestinal Neoplasms

Digestive System Neoplasms

Gastrointestinal Diseases

Carcinoma

Neoplasms, Glandular and Epithelial

Neoplasms by Histologic Type

Esophageal Diseases

Esophageal Cancer

Bile Duct Cancer

Stomach Cancer

Short-term starvation for a timeframe beginning 24h prior to chemotherapy administration, lasting until 6h after administration

Recent pre-clinical data provide strong evidence that short-term starvation before the administration of cytostatic drugs for the chemotherapy of solid tumors leads to significantly higher efficacy and lower toxicity levels. However, these findings have so far not been validated in patients. The aim of this trial is to provide first clinical evidence regarding the impact of pre-chemotherapeutic short-term starvation on response to therapy (primary endpoint). Additionally, progression-free survival, adverse events, and overall survival will be monitored (secondary endpoints). In perspective, short-term starvation before chemotherapy could represent a simple and secure way to improve both efficacy and tolerance of chemotherapies at low cost.

Short-term Starvation vs. Normal Diet Before Chemotherapy of Solid Tumors

Primary endpoint of this study is to assess the improvement in response to therapy for patients undergoing short-term starvation before chemotherapy of solid tumors in comparison to patients without dietary restrictions. Response to therapy on MRI or CT scancs will be measured using the RECIST criteria version 1.1.

University Hospital Tuebingen

Dr. med.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Incidence of Refeeding Syndrome in Consecutively Admitted Patients	NCT05967858	Refeeding Syndr... Starvation Phosphate Defic...	observation	18 Years -	University of Copenhagen
Incidence of Refeeding Syndrome in Consecutively Admitted Patients	NCT05967858	Refeeding Syndr... Starvation Phosphate Defic...	observation	18 Years -	University of Copenhagen
Short-term Starvation vs. Normal Diet Before Chemotherapy of Solid Tumors	NCT02607826	Cholangiocarcin... Pancreatic Duct... Colorectal Canc... Gastric Cancer Adenocarcinoma ... Esophagus Cance...	Starvation	18 Years -	University Hospital Tuebingen
Short-term Starvation vs. Normal Diet Before Chemotherapy of Solid Tumors	NCT02607826	Cholangiocarcin... Pancreatic Duct... Colorectal Canc... Gastric Cancer Adenocarcinoma ... Esophagus Cance...	Starvation	18 Years -	University Hospital Tuebingen

Spots Global Cancer Trial Database for starvation

Every month we try and update this database with for starvation cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for starvation

Every month we try and update this database with for starvation cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for starvation cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.