Neoplasms

Digestive System Diseases

All Conditions

Colorectal Neoplasms

Intestinal Neoplasms

Gastrointestinal Neoplasms

Digestive System Neoplasms

Gastrointestinal Diseases

Colonic Diseases

Intestinal Diseases

Rectal Diseases

Herbal and Botanical

All Drugs and Chemicals

Cola

Participants in this arm will receive a letter from their provider informing them they are overdue for colon cancer screening and requesting their participation in colonoscopy, and including a referral for the procedure at a local endoscopy center. Participants will be provided a phone number if interested in navigated colonoscopy scheduling.

Participants in this arm will receive a letter from their provider informing them they are overdue for colon cancer screening and requesting their participation in their choice of either colonoscopy or mailed fecal immunochemical testing (FIT). The letter will include both a referral for the colonoscopy at a local endoscopy enter and a FIT kit with a lab requisition and instructions for completion.

Participants in this arm will receive a letter from their provider informing them they are overdue for colon cancer screening and requesting their participation in FIT testing. The letter will include a FIT kit with lab requisition and instructions for completion.

Mailed letter asking participants to complete CRC screening by colonoscopy

Colonoscopy Only

Mailed letter and FIT test asking participants to complete CRC screening by their choice of either colonoscopy or mailed FIT

Choice

Mailed letter and FIT test asking participants to complete CRC screening by mailed FIT

FIT Only

Shivan Mehta, MD

This is a 3-arm randomized trial aimed at increasing rates of participation in colorectal cancer (CRC) screening by outreach to patients' homes using choice architecture informed by behavioral science principles.

The investigators will evaluate the effectiveness of mailed outreach with choice between colonoscopy and FIT, and FIT alone, as compared to colonoscopy alone in increasing CRC screening rates.

Choice Architecture and Mailed Colorectal Cancer Screening Outreach in a Community Health Setting

Screening completion rate in arm 2 (Choice) to arm 1 (Colonoscopy only) and arm 3 (FIT only) separately.

The proportion of patients choosing either FIT or Colonoscopy in study arm 2 (Choice)

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Choice Architecture and Mailed Colorectal Cancer Screening Outreach in a Community Health Setting	NCT04711473	Colorectal Canc...	Colonoscopy Onl... Choice FIT Only	50 Years - 74 Years	Abramson Cancer Center at Penn Medicine
Choice Architecture and Mailed Colorectal Cancer Screening Outreach in a Community Health Setting	NCT04711473	Colorectal Canc...	Colonoscopy Onl... Choice FIT Only	50 Years - 74 Years	Abramson Cancer Center at Penn Medicine

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