Nutritional and Metabolic Diseases

Gland and Hormone Related Diseases

All Conditions

Neoplasms

Digestive System Diseases

Diabetes Mellitus, Type 2

Diabetes Mellitus

Colorectal Neoplasms

Metabolic Diseases

Glucose Metabolism Disorders

Endocrine System Diseases

Intestinal Neoplasms

Gastrointestinal Neoplasms

Digestive System Neoplasms

Gastrointestinal Diseases

Colonic Diseases

Intestinal Diseases

Rectal Diseases

Based on national survey data and a community engagement participatory implemention planning group, a tailored combination of widely accepted implementation strategies will be adapted for targeting CRC screening for patients with diabetes. These strategies include but are not limited to: identification of patient and practice-level barriers, patient education, provider reminders, and audit and feedback.

Strategies in the toolkit include but are not limited to: identification of patient and practice-level barriers, routine tailored patient reminders, provider reminders, \& clinic staff feedback.

Targeted CRC Screening Toolkit

Denalee O'Malley, PhD

Cilgy Abraham

Cigil Abraham

This mixed methods study evaluates the effectiveness and feasibility of a multi-level (patient, team, organizations) intervention to optimize CRC screening for patients with diabetes in primary care safety-net settings.

Aim 3 is a hybrid type 2 effectiveness-implementation pilot study in six primary care safety net clinics. This single-arm study uses a pre-post design to evaluate the targeted implementation strategies impact on: (1) preliminary effectiveness and (2) implementation (i.e., feasibility and acceptability) and a mixed-method comparative case study learning evaluation for safety-net primary care adoption and implementation. Implementation strategies that will be tested were developed through a stakeholder engaged, community-based participatory implementation planning approach. This study uses a tailored combination of implementation strategies that include but are not limited to: identification of patient and practice-level barriers, patient education matierals, patient reminders provider/clinical team education, clinical champions, and audit and feedback. The impact of this evaluation will be measure using mixed methods to assess Exploration, Preparation, Implementation factors related to how organizational and contextual variables affect adoption and implementation for targeting CRC screening among patients with diabetes in safety net clinics at 12 months post intervention. Aim 3 surveys 20 clinicians and staff from 6 clinics (n=120) and conducts key-informant interviews with 8 clinic and staff members at pre- and post-implementation (who have participated in the survey; n=96) and evaluates aggregate data for 30 patients across six clinics (n=180).

The study uses a pilot, pre-post, hybrid effectiveness-implementation design to compare the adapted implementation strategy to usual care on: (1) effectiveness and (2) implementation outcomes.

Aim 3, Optimizing CRC Screening in Patients With Diabetes in Safety-net Primary Care Settings

Optimizing Colorectal Cancer Screening Among Patients With Diabetes in Safety-Net Primary Care Settings: Targeting Implementation Approaches

Implementation: participants opt-out and non-adherence rates based on proportion of overall eligible participants

Clinic-level proportion of eligible participants who were contacted for screening based on implementation plan targets

Preliminary effectiveness: Clinic-level proportion of participants who complete a colonoscopy

Preliminary Effectiveness: Clinic-level proportion of participants who receive any CRC screening

Preliminary Effectiveness: Clinic-level CRC screening by glucose control (controlled vs. uncontrolled)

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Aim 3, Optimizing CRC Screening in Patients With Diabetes in Safety-net Primary Care Settings	NCT05785780	Colorectal Canc... Diabetes Mellit...	Targeted CRC Sc...	50 Years - 74 Years	Rutgers, The State University of New Jersey
Aim 3, Optimizing CRC Screening in Patients With Diabetes in Safety-net Primary Care Settings	NCT05785780	Colorectal Canc... Diabetes Mellit...	Targeted CRC Sc...	50 Years - 74 Years	Rutgers, The State University of New Jersey
Aim 3, Optimizing CRC Screening in Patients With Diabetes in Safety-net Primary Care Settings	NCT05785780	Colorectal Canc... Diabetes Mellit...	Targeted CRC Sc...	50 Years - 74 Years	Rutgers, The State University of New Jersey

Spots Global Cancer Trial Database for targeted crc screening toolkit