therapeutic education program which aims is to improve the adherence to the treatment and management of adverse effects of this treatment in patients taking an oral chemotherapy for active cancer

therapeutic education program

Aurélie BOURMAUD, MD

David PEROL, MD

Claire Falandry, PhDMD

Cécile Vassal, MD

Therapeutic education is an effective way to support the prescription of oral chemotherapy in oncology. It aims to increase adherence to treatment, to better control the side effects and reduce unplanned readmissions. The three major oncology institutions in the Rhône-Alpes region (Hospices Civils de Lyon, the Centre Léon Bérard Cancer Institute and Lucien Neuwirth) decided to collaborate on a project to implement an adapted Therapeutic Education Program context of each of these institutions.

The objective of this study is to evaluate the implementation of the intervention in the 3 participating centers, over 1 year:

1. Assess the achievement of the target population
2. Evaluate the adaptation of intervention in context
3. Evaluate the effectiveness of the intervention (impact): effectiveness in real life, identification of interactions with the environment linked to the center, identification of unintended effects of the intervention.
4. Assessing the sustainability of the intervention

Assesment of the Implementation of a Therapeutic Educational Intervention Affecting Adherence to Oral Chemotherapy

Assessment of the Implementation of a Therapeutic Educational Intervention Affecting Adherence to Oral Chemotherapy

Questionnaire composed of numerous questions dealing with patient's knowledge about his/her disease, treatment and treatment's side effects . Answers are quoted in Yes/No and a global scoring is made with all answers. Final measure is a percentage of good answers.

measured with the Hospital Anxiety Depression Scale (Zigmond \& Snaith, 1983 ), wich gives separated results about the level of anxiety and of depression according to the level of scoring to a set of 14 questions. Questions are rated from 0-3, and the anxiety and depression subscale scores range from 0-21. The cutoff for each subscale is eight.

Hospices Civils de Lyon

Centre Leon Berard

Institut de Cancérologie de la Loire

Neoplasms

Urinary Tract, Sexual Organs, and Pregnancy Conditions

All Conditions

Prostatic Neoplasms

Genital Neoplasms, Male

Urogenital Neoplasms

Genital Diseases

Genital Diseases, Male

Urogenital Diseases

Prostatic Diseases

Male Urogenital Diseases

All Drugs and Chemicals

Androgens

patients attend three sessions of therapeutic education

Jean-Etienne Terrier, MD

The purpose of the study is to build and assess the feasibility of a therapeutic education program, constructed in collaboration with the urologists of the University Hospital of Saint Etienne. The aim of this therapeutic education program is to delay the onset or to reduce the amplitude of the development of insulin resistance and side effects of androgen deprivation therapy in patients treated with androgen deprivation in the context of an evolutive prostate cancer.

Feasibility Study of an Intervention Therapeutic Education for Patients Treated With Androgen Deprivation

Skin and Connective Tissue Diseases

Breast Neoplasms

Breast Diseases

Skin Diseases

Patients follow the classic support prescription of hormonotherapy

Patients follow the 4 sessions of PEP hormonotherapy. The therapeutic education prgram is led by a trained educational team, inside a prevention center : Hygée centre.

Aurélie Bourmaud, MD

The purpose of this study is to evaluate the feasibility and the effectiveness of a patient education program on patients' adherence to adjuvant hormone therapy (anti-estrogen or aromatase inhibitors) for breast cancer, in collaboration with teams of sociologists, patient education and medical oncologists.

Therapeutic Education Intervention in Breast Cancer: PEPs Hormonotherapy

Development and Evaluation of a Therapeutic Education Intervention Focused on the Accession of Patients Treated With Hormonal Therapy in the Management of Breast Cancer: PEPs Hormonotherapy

compliance measure with prescription refillment and questionnaire. At the inclusion and at the end of the study

measure of the patients' competence with a specific questionnaire of scenarii

Measuring the level of knowledge of patients with a specific quizz

Measuring the level of patient anxiety with HAD scale

Measuring the level of confidence with a visual analogic scale

quality of life evaluated with the EQ-5D questionnaire

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Assesment of the Implementation of a Therapeutic Educational Intervention Affecting Adherence to Oral Chemotherapy	NCT02828449	Neoplasm	therapeutic edu...	18 Years -	Institut de Cancérologie de la Loire
Assesment of the Implementation of a Therapeutic Educational Intervention Affecting Adherence to Oral Chemotherapy	NCT02828449	Neoplasm	therapeutic edu...	18 Years -	Institut de Cancérologie de la Loire
Feasibility Study of an Intervention Therapeutic Education for Patients Treated With Androgen Deprivation	NCT02460549	Prostate Cancer	therapeutic edu...	18 Years -	Institut de Cancérologie de la Loire
Feasibility Study of an Intervention Therapeutic Education for Patients Treated With Androgen Deprivation	NCT02460549	Prostate Cancer	therapeutic edu...	18 Years -	Institut de Cancérologie de la Loire
Therapeutic Education Intervention in Breast Cancer: PEPs Hormonotherapy	NCT02300675	Breast Cancer	therapeutic edu...	18 Years -	Institut de Cancérologie de la Loire
Therapeutic Education Intervention in Breast Cancer: PEPs Hormonotherapy	NCT02300675	Breast Cancer	therapeutic edu...	18 Years -	Institut de Cancérologie de la Loire

Spots Global Cancer Trial Database for therapeutic education program