Symptoms and General Pathology

All Conditions

Neoplasms

Urinary Tract, Sexual Organs, and Pregnancy Conditions

Gland and Hormone Related Diseases

Syndrome

Polycystic Ovary Syndrome

Cysts

Ovarian Cysts

Ovarian Diseases

Adnexal Diseases

Genital Diseases, Female

Genital Diseases

Urogenital Diseases

Female Urogenital Diseases

Pregnancy Complications

Female Urogenital Diseases and Pregnancy Complications

Gonadal Disorders

Endocrine System Diseases

All Drugs and Chemicals

Androgens

1. Oligomenorrhea/amenorrhea
2. Clinical androgen excess or biochemical androgen excess
3. Polycystic ovary showed by gynecological ultrasound

This study does not involve any interventions

Manna Zhang, Dr

Manna Zhang, Ph.D

Shen Qu, Dr

The investigators collected clinical data and serum samples of patients with polycystic ovary syndrome (PCOS) in this study, used statistical software such as SPSS for date analysis, and used experimental techniques such as ELISA and flow cytometry to detect serum samples, aiming to explore the relationship between the body anthropometry, skin conditions, psychosomatic status, diet, sleep, exercise, glucose and lipid metabolism, gonadal hormones, and body fat distribution in patients with polycystic ovary syndrome, and to discovery new biomarkers. Multidisciplinary exploration of the mechanisms of disease occurrence and development, the establishment of a PCOS multicenter, multidisciplinary and multidimensional clinical research database, combined with the established statistical analysis strategy for big data and analysis, to promote the realization of more accurate personalized medicine.

Multidisciplinary Diagnosis and Treatment of Polycystic Ovary Syndrome

Multidisciplinary Combined Precise Diagnosis and Treatment of Polycystic Ovary Syndrome

Fibrinogen-like-protein 1 (FGL1), is a novel hepatokine that plays an important role in hepatic steatosis, insulin resistance and obesity. There is no maximum or minimum value for this parameter and the higher scores mean a worse outcome.

WHR=Waist Circumference(cm)/Hip Circumference(cm)

physiological parameter,the total number of menstrual periods in the last year

The minimum value of Ferriman-Gallwey score is 0 and the maximum value is 44. An Ferriman-Gallwey score greater than or equal to 6 is considered to be a clinical manifestation of androgen excess.

Homeostatic model assessment insulin resistance index

The factor reflects that the organism is in an inflammatory state. There is no maximum or minimum value for the factor and the higher scores mean a worse outcome.

IL-6. The factor reflects that the organism is in an inflammatory state. There is no maximum or minimum value for the factor and the higher scores mean a worse outcome.

A adipocytokine.The factor is expressed in adipose tissue and is related to specific adipose tissue function.

A adipocytokine. The factor is expressed in adipose tissue and is related to specific adipose tissue function.

Shanghai 10th People's Hospital

Director, Principal Investigator, Clinical Professor

The investigators collected clinical data and serum samples of patients with polycystic ovary syndrome in this study, used statistical software such as SPSS for data analysis, and used experimental techniques such as ELISA to detect serum samples, aiming to explore the relationship between the body anthropometry, glucose and lipid metabolism, gonadal hormones and body fat distribution in patients with polycystic ovary syndrome and to discovery new biomarkers and promote the realization of more accurate personalized medicine.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Multidisciplinary Diagnosis and Treatment of Polycystic Ovary Syndrome	NCT06047574	Polycystic Ovar...	This study does...	18 Years - 45 Years	Shanghai 10th People's Hospital
Analysis of Clinical Characteristics and Study of Diagnostic Markers in Patients With Polycystic Ovary Syndrome	NCT05063383	Polycystic Ovar...	This study does...	18 Years - 45 Years	Shanghai 10th People's Hospital

Spots Global Cancer Trial Database for this study does not involve any interventions