Neoplasms

Skin and Connective Tissue Diseases

All Conditions

Symptoms and General Pathology

Nervous System Diseases

Breast Neoplasms

Pain, Postoperative

Pain

Breast Diseases

Skin Diseases

Postoperative Complications

Neurologic Manifestations

Anti-Arrhythmia Agents

Channel Blockers

Central Nervous System Depressants

All Drugs and Chemicals

Herbal and Botanical

Lidocaine

Anesthetics

Bupivacaine

Patients who receive general anesthesia after erector spina plane block

Patients who receive general anesthesia after thoracic epidural block

After skin infiltration with 2 ml of 2% lidocaine, an 18 G tuohy needle will be directed between the erector spina muscle and the transverse process of the T4 vertebra using the in-plane technique. The location of the needle will be confirmed by hydrodissection with saline after touching the transverse process. After the plan open, 5 ml of 2% lidocaine, 10 ml of 0.5% bupivacaine and 10 ml of saline, including hydrodissection, will be given in a total amount of 25 ml. Then a 20-G epidural catheter will be inserted 3-4 cm and fixed.

Erector spina plane block before general anaesthesia

After skin infiltration with 2 ml of 2% lidocaine, an 18 G tuohy needle will be entered through the T4-5 interspinous space (median or paramedian approach). After reaching the thoracic epidural area by loss of resistance method, the epidural catheter will be advanced and fixed to remain 3-4 cm in the epidural area. Following the test dose (2 ml of 2% lidocaine), 3 ml of 2% lidocaine, 5 ml of 0.5% bupivacaine and 5 ml of saline will be administered intermittently in a total volume of 15 ml.

Thoracic epidural block before general anaesthesia

Gulay ERDOGAN KAYHAN, MD

The aim of this randomised controlled and double-blind study, is to compare the effects of erector spinae plane (ESP) and thoracic epidural (TEA) blocks on peri-operative hemodynamics and analgesia in patients undergoing unilateral mastectomies due to malignancy.

Patients will be randomised into two groups as Group E (those who received general anesthesia after the erector spina plan block) and Group T (those who received general anesthesia after thoracic epidural block).

After the block skin conductivity (galvanic skin response - GSR), body temperature changes, sympathetic and sensory block levels, peri-operative hemodynamic data, postoperative pain scores and analgesic consumption will be recorded.

Comparison of Erector Spina Plane Block and Thoracic Epidural Block

Comparison of Erector Spina Plane Block and Thoracic Epidural Block in Breast Surgery

Skin conductivity will be measured by galvanic skin response (GSR)

Skin temperature of bilateral thorax will be measured

Hot cold test of bilateral thorax will be measured

Peri-operative heart rate and mean arterial pressure will be recorded

Pain score will be measured with visual analog scale (0-no pain; 10-worst pain) during movement and rest.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Comparison of Erector Spina Plane Block and Thoracic Epidural Block	NCT04702061	Breast Neoplasm... Pain, Postopera...	Erector spina p... Thoracic epidur...	18 Years - 70 Years	Inonu University
Comparison of Erector Spina Plane Block and Thoracic Epidural Block	NCT04702061	Breast Neoplasm... Pain, Postopera...	Erector spina p... Thoracic epidur...	18 Years - 70 Years	Inonu University

Spots Global Cancer Trial Database for thoracic epidural block before general anaesthesia