Symptoms and General Pathology

All Conditions

Musculoskeletal Diseases

Neoplasms

Skin and Connective Tissue Diseases

Nervous System Diseases

Fibrosis

Disease Susceptibility

Contracture

Dupuytren Contracture

Fibroma

Neoplasms, Fibrous Tissue

Neoplasms, Connective Tissue

Neoplasms, Connective and Soft Tissue

Neoplasms by Histologic Type

Muscular Diseases

Connective Tissue Diseases

Disease Attributes

all patients will be checked for signs of fibrosis diathesis. This will be done by examining their hands for Dupuytren's nodules and contractures and recording risk factors associated with increased severity and risk of recurrence of Dupuytren's contracture. These include family history, bilateral DD, and ectopic lesions, age of onset less than 50 years, male gender, Ledderhose disease, first ray involvement, multiple ray involvement and ectopic fibromatosis.

This way, two groups of patients will be identified: those with and those without signs of fibrosis diathesis.

Total knee arthroplasty

At the standard follow-up moment one year after primary TKA for gonarthrosis, all patients will be checked for signs of fibrosis diathesis. This will be done by examining their hands for Dupuytren's nodules and contractures and recording risk factors associated with increased severity and risk of recurrence of Dupuytren's contracture. These include family history, bilateral DD, and ectopic lesions, age of onset less than 50 years, male gender, Ledderhose disease, first ray involvement, multiple ray involvement and ectopic fibromatosis.

This way, two groups of patients will be identified: those with and those without signs of fibrosis diathesis. For both groups, the range of motion (ROM) of the operated knee at 3 and 6 months will be retrieved in the charts, the ROM at 12 months will be measured at that time. Also, additional procedures performed to increase ROM postoperatively will be retrieved from the charts (e.g. continuous passive motion, mobilization under anesthesia). Other causes for knee stiffness will have to be recorded, since these will be the most important exclusion criteria.

In the patients with clear signs of finger contractures, any impression of increase of contracture over the past 12 months will be recorded.

Knee Stiffness in Fibrosis Diathesis

Does Fibrosis Diathesis Influence the Recovery of Knee Mobility After Total Knee Replacement?

University Hospital Pellenberg

Fellow

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Knee Stiffness in Fibrosis Diathesis	NCT02294890	Knee Replacemen... Fibrosis Dupuytren's Dis...	Total knee arth...	50 Years -	University Hospital Pellenberg
Knee Stiffness in Fibrosis Diathesis	NCT02294890	Knee Replacemen... Fibrosis Dupuytren's Dis...	Total knee arth...	50 Years -	University Hospital Pellenberg

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