Neoplasms

Skin and Connective Tissue Diseases

All Conditions

Breast Neoplasms

Breast Diseases

Skin Diseases

Participants come to the Energy Balance Center to exercise 3 times a week for 12 weeks.

Participants receive written materials and instructions on how to perform their exercises.

Participants walk uphill on a treadmill for a total of 33 minutes 3 times a week for 12 weeks.

Participants complete questionnaires about their quality of life, exercise experience, and level of fatigue at baseline and at 12 weeks.

One (1) time each month, participant attends a motivational session.

Participants come to the Energy Balance Center to exercise 3 times a week for 12 weeks.

Participants receive written materials and instructions on how to perform their exercises.

Participants walk uphill on a treadmill or use a stationary bicycle continuously for 41 minutes 3 times a week for 12 weeks.

Participants complete questionnaires about their quality of life, exercise experience, and level of fatigue at baseline and at 12 weeks.

One (1) time each month, participant attends a motivational session.

Participants receive written materials and counseling by an exercise physiologist.

Participants called by a member of the study staff 1 time each week for 12 weeks and asked about any exercise they have done and their weight loss goals.

Participants complete questionnaires about their quality of life, exercise experience, and level of fatigue at baseline and at 12 weeks.

One (1) time each month, participant attends a motivational session.

High-Intensity Interval Training (HIIT) Group: Participants walk uphill on a treadmill for a total of 33 minutes 3 times a week for 12 weeks.There is a 5-minute warm up, followed by four 4-minute intervals. Between each interval, participant walks for 3 minutes. There is a 3 minute cool down.

Moderate-Intensity Continuous Training (MICT) Group: Participants walk uphill on a treadmill or use a stationary bicycle continuously for 41 minutes 3 times a week for 12 weeks.

Exercise

Participants complete questionnaires about their quality of life, exercise experience, and level of fatigue at baseline and at 12 weeks. These should take a total of about 15 minutes to complete.

Questionnaires

One (1) time each month, participant attends a motivational session for 12 weeks.

Motivational Session

Participants called by a member of the study staff 1 time each week for 12 weeks and asked about any exercise they have done and their weight loss goals. Each phone call should take about 15 minutes.

Phone Call

High-Intensity Interval Training (HIIT) Group and Moderate-Intensity Continuous Training (MICT) Group: Participants receive written materials and instructions on how to perform their exercises.

Control Group: Participants receive written materials and counseling by an exercise physiologist.

Printed Materials

Susan C. Gilchrist, MD

The goal of this research study is to learn if there is a level of exercise training that is more effective in lowering biomarker levels that are linked to breast cancer risk. Biomarkers are found in the blood/tissue and may be related to your reaction to exercise.

This is an investigational study. Up to 72 participants will be enrolled in this study. All will take part at MD Anderson.

Study Groups:

If you agree to take part in this research study, you will be randomly assigned (as in a roll of dice) to 1 of 3 study groups. This is done because no one knows if one study group is better, the same, or worse than the other group. You will have an equal chance of being assigned to each group:

* If you are in Group 1, you will take part in high-intensity interval (HIIT) exercise.
* If you are in Group 2, you will take part in moderate-intensity exercise.
* If you are in Group 3, you will not take part in any assigned exercise, but you will receive written materials and counseling by an exercise physiologist.

If you are in Group 1 or Group 2, you will also receive written materials and instructions on how to perform your exercises.

Physical Activity:

If you are in Group 1 or 2, you will come to the Energy Balance Center to exercise 3 times a week for 12 weeks.

If you are in Group 1, you will walk uphill on a treadmill for a total of 33 minutes. There will be a 5-minute warm up, followed by four 4-minute intervals. Between each interval, you will walk for 3 minutes. There will be a 3 minute cool down.

If you are in Group 2, you will exercise at the Energy Balance Center 3 times a week. You will walk uphill on a treadmill or use a stationary bicycle continuously for 41 minutes.

If you are in Group 3, 1 time each month while you are on study, you will be called by a member of the study staff and asked about any exercise you have done and your weight loss goals. Each phone call should take about 15 minutes.

The exercise training intensity may be reduced or stopped temporarily if you experience side effects.

Length of Study:

No matter which group you are in, your participation in this study will be over after 12 weeks. You will be taken off study if you have intolerable side effects.

Study Visits:

All participants will visit the MD Anderson Behavioral Research and Treatment Center for each study visit.

At baseline:

* You will have a cardiopulmonary exercise test (CPET) to check your lung function. The CPET checks how well your lungs are working by measuring how much oxygen and carbon dioxide your lungs take in and release when you breathe. To perform this test, you will be asked to walk on a treadmill until you reach a point that you can no longer exercise. You will be breathing into the machine while you walk. This test will take about 30 minutes to complete. The study doctor will be present for each CPET and available to respond to any complication.
* You will have an EKG to check your heart function. The study doctor will be present for each EKG you have.
* Blood (about 1½ tablespoons) will be drawn for biomarker testing. You will be asked to fast (eat nothing and drink only water) for at least 12 hours before each blood draw as part of this study.
* You will have a dual-energy x-ray absorptiometry (DEXA) scan to measure your body mass.
* You will complete a questionnaire that will ask you about your demographics (age, race, and so on), past medical history, and lifestyle habits. This questionnaire should take about 5 minutes to complete.
* You will complete 5 questionnaires about your quality of life, exercise experience, and level of fatigue. These should take a total of about 15 minutes to complete.

At 6 weeks:

* You will have a CPET.
* You will have an EKG.

At 12 weeks:

* You will have a CPET.
* Blood (about 1½ tablespoons) will be drawn for biomarker testing.
* You will have an EKG.
* You will have a DEXA scan.
* You will complete the same questionnaires that you completed at baseline.
* If you are in Group 1 or 2, you will be interviewed by a member of the study staff. You will be asked 5 questions about your experience with your assigned exercise program. It should take about 5 minutes to complete.

One (1) time each month, you will attend a motivational session. During this session, you will discuss strategies for overcoming barriers that may be keeping you from attending or completing your exercises. You will also talk about continuing physical activity after you complete the program. This session should last about 15-30 minutes.

Additional Information:

* Trained health professionals will be present at all study visits to address any symptoms during exercise. If you feel that you are having difficulty breathing, experiencing dizziness, or are having any heart related symptoms while exercising at home, please stop exercising and call 911 immediately.
* Clinical information such as your name, patient medical record number, age, gender, body mass index (BMI), zip code, and your complete medical history will be collected from your medical record.
* If you are in Group 1 or Group 2, you will receive text messages before each exercise session to remind you to attend. You will be responsible for any text messaging charges. Standard text message rates will apply.

High-Intensity Interval Training for Women at Heightened Risk for Breast Cancer

Trials judged feasible if:

At least 45% of screened patients meet inclusion criteria, 2. At least 50% of patients who meet the inclusion criteria consent, 3. Adherence in HIIT and MICT is larger than 80%, and 4. Retention rate is larger than 80%.

M.D. Anderson Cancer Center

Symptoms and General Pathology

Urinary Tract, Sexual Organs, and Pregnancy Conditions

Gland and Hormone Related Diseases

Nutritional and Metabolic Diseases

Syndrome

Polycystic Ovary Syndrome

Insulin Resistance

Hyperinsulinism

Metabolic Diseases

Glucose Metabolism Disorders

Cysts

Ovarian Cysts

Ovarian Diseases

Adnexal Diseases

Genital Diseases, Female

Genital Diseases

Urogenital Diseases

Female Urogenital Diseases

Pregnancy Complications

Female Urogenital Diseases and Pregnancy Complications

Gonadal Disorders

Endocrine System Diseases

Hypoglycemic Agents

All Drugs and Chemicals

Insulin

Insulin, Globin Zinc

the patient will be received whole body vibration for three times/ week in addition to aerobic exercise for 3 times per week, 45 minutes per session for eight weeks

Moderate intensity aerobic exercise in form of walking on treadmill for 3 times per week, 45 minutes per session for eight weeks

the patients will stand on whole body vibration device with maintaining squatting position while keeping their trunk extended. The first training session will be consisted of three sets of 1 min and will be separated by a 1-min of standing rest. intensity will 1 mm. Then one set will be added every session

whole body vibration

Females will be asked to perform moderate intensity aerobic exercise for 45 minutes for 3 times per week for 8 weeks

Treadmill

Mai M Ali Shehata, lecturer

The purpose of this study is to investigate the effect of whole body vibration on insulin resistance in females with polycystic ovarian syndrome

polycystic ovarian syndrome is a complex endocrine condition characterized by metabolic abnormalities such as insulin resistance, excess weight or obesity, diabetes, and an increased risk of cardiovascular disease.Despite previous studies reported that physical exercise improves insulin resistance in females with polycystic ovarian syndrome, there is no study yet investigate the effect of whole body vibration on insulin resistance

Effect of Whole Body Vibration on Insulin Resistance in Females With Polycystic Ovarian Syndrome

Estimate insulin resistance (IR), it will be calculated according to the formula: fasting insulin (microU/L) x fasting glucose (nmol/L)/22.5.

The formula = waist circumference / hip circumference.

Cairo University

Lecturer

Fatigue

Resistance exercises will be involved in this technique are for upper and lower limb (Exercise program including shoulder flexion, abduction and horizontal adduction, elbow extension and flexion, calf raise, leg extension and squatting) three times daily and five times per week. The 1 repetition maximum (1RM) is measured at baseline and following the intervention. Initially, participants will do two circuits using 50% of their 1RM and repeat them 10 times for the first and second weeks, progressing to two circuits, using 60% of their 1RM and repeat 10 times for the third and fourth weeks. In fifth and sixth weeks, participants will do three circuits using 60% of their 1RM and repeat 10 times. In the last 6 weeks, patients will do three circuits using 70% of their 1RM and repeat 10 times. Time of exercise equal time of rest

Aerobic training (AT) program of submaximal intensity will include a 45-minute session five times per week under the supervision of the researcher. Aerobic exercise will consist of three phases: warm-up, training and cool down. At the beginning of exercise session, subjects will have a ten-minute warm-up. The warm up protocol will be slowly running on treadmill. Then, the warm-up phase will be followed by the training phase. At baseline, the training phase will be commenced with two 30- minute running on treadmill at 50% of their maximal heart rate (MHR) in the first week and increased to 70% MHR by the final week of training. By the end of exercise session, subjects will have a five-minute cool down. The cool down protocol will be slowly running on treadmill. The vital measures such as HR and blood pressure was monitored before patient left the department (Dimeo et al.,2016), maximum heart rate will be calculated using the formula: (HR Max =220- age)

Treadmill is not used to harness power, but as exercise machines for running or walking in one place. Rather than the user powering the mill, the machine provides a moving platform with a wide conveyor belt driven by an electric motor or a flywheel. The belt moves to the rear, requiring the user to walk or run at a speed matching that of the belt. The rate at which the belt moves is the rate of walking or running. Thus, the speed of running may be controlled and measured

Resistance exercises will be involved in this technique are for upper and lower limb (Exercise program including shoulder flexion, abduction and horizontal adduction, elbow extension and flexion, calf raise, leg extension and squatting)

resisted exercises

Lamiaa sa tolba, ASS.lecturer

Amal mo abdel baky, Professor

Lamiaa S Saleh, Master

Amal mo abdel baky, professor

The purpose of the study is to evaluate which is more effective resistance or aerobic exercises on cancer related fatigue and immunity in breast cancer patients undergoing adjuvant chemotherapy.

The problem of cancer related fatigue and decreased immunity, as a result of treatment with adjuvant chemotherapy in breast cancer patients is not well known.

Fatigue and decreased immunity have a negative impact on work, social relationships, mood, and daily activities and cause significant impairment in overall quality of life, Furthermore the need of this study is developed from the lack of information in the published studies about the effect of the treatment with chemotherapy among breast cancer patients on inducing fatigue and decreasing immunity and the effect of resistance and aerobic exercises on improving these changes.

RESISTANCE VERSUS AEROBIC EXERCISES ON Breast Cancer Patients

Resistance Versus Aerobic Exercises On Cancer Related Fatigue And Immunity In Breast Cancer Patients Undergoing Adjuvant Chemotherapy

The Fatigue Assessment Scale (FAS) is quick and easy to complete for patients, and not time consuming. It is also helpful for physicians and other health care workers in the follow-up of their patients. The FAS has proven to be a valid questionnaire to assess fatigue in cancer patients, but also in many other patients with chronic diseases

Hemoglobin levels are measured by a blood test. Hemoglobin, or Hb, is usually expressed in grams per deciliter (g/dL) of blood. A low level of hemoglobin in the blood relates directly to a low level of oxygen

White blood cells (also called leukocytes and abbreviated as WBCs) are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders. All white blood cells are produced and derived from multipotent cells in the bone marrow known as hematopoietic stem cells. Leukocytes are found throughout the body, including the blood and lymphatic system

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
High-Intensity Interval Training for Women at Heightened Risk for Breast Cancer	NCT02923401	Disorders of Br...	Exercise Questionnaires Motivational Se... Phone Call Printed Materia...	18 Years - 55 Years	M.D. Anderson Cancer Center
Effect of Whole Body Vibration on Insulin Resistance in Females With Polycystic Ovarian Syndrome	NCT05215223	Polycystic Ovar... Insulin Resista...	whole body vibr... Treadmill	20 Years - 35 Years	Cairo University
High-Intensity Interval Training for Women at Heightened Risk for Breast Cancer	NCT02923401	Disorders of Br...	Exercise Questionnaires Motivational Se... Phone Call Printed Materia...	18 Years - 55 Years	M.D. Anderson Cancer Center
RESISTANCE VERSUS AEROBIC EXERCISES ON Breast Cancer Patients	NCT04656457	Breast Cancer	Treadmill resisted exerci...	30 Years - 60 Years	Cairo University
High-Intensity Interval Training for Women at Heightened Risk for Breast Cancer	NCT02923401	Disorders of Br...	Exercise Questionnaires Motivational Se... Phone Call Printed Materia...	18 Years - 55 Years	M.D. Anderson Cancer Center

Spots Global Cancer Trial Database for treadmill

Every month we try and update this database with for treadmill cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for treadmill

Every month we try and update this database with for treadmill cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for treadmill cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.