Neoplasms

Skin and Connective Tissue Diseases

All Conditions

Breast Neoplasms

Breast Diseases

Skin Diseases

Treatment will be recommended after reviewing the profiling analysis

treated recommended

Stephen Anthony, DO

This study will use proteomic and genomic profiling to analyze tumor tissue to see if treatment selected by this analysis will benefit patients.

To examine the impact of targeted therapy for breast cancer based upon proteomic and genomic profiling using RPMA, IHC analysis, RNA-Seq, and Exome sequencing on PFS and GMI.

A Pilot Study Utilizing Proteomic and Genomic Profiling for Patients With Metastatic Breast Cancer

A Pilot Study Utilizing Proteomic and Genomic Profiling by Reverse Phase Protein Microarray (RPMA), IHC Analysis, RNA Seq, and Exome Sequencing of Patients' Tumors to Find Potential Targets and Select Treatments for Patients With Metastatic Breast Cancer

The data from this exploratory analysis will help generate the hypothesis for a future prospective study.

Determine the impact of targeted therapy for breast cancer based upon proteomic and genomic profiling using RPMA, IHC analysis, RNA-Seq, and Exome sequencing on PFS and GMI.

Record the frequency with which proteomic, IHC, and genomic profiling analysis of a patient's tumor by RPMA, IHC analysis, RNA-Seq, and Exome sequencing yields a target against which there is an FDA-approved agent or therapeutic regimen.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
A Pilot Study Utilizing Proteomic and Genomic Profiling for Patients With Metastatic Breast Cancer	NCT01919749	Metastatic Brea...	treated recomme...	18 Years -	Translational Drug Development
A Pilot Study Utilizing Proteomic and Genomic Profiling for Patients With Metastatic Breast Cancer	NCT01919749	Metastatic Brea...	treated recomme...	18 Years -	Translational Drug Development

Spots Global Cancer Trial Database for treated recommended