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Genital Diseases, Male

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Male Urogenital Diseases

Treatment with Tookad VTP

John Trachtenberg, MD, FRCS(C)

This is a multi-centre, phase II, open-label, 12-month clinical trial for patients previously treated with WST09 (Tookad) who have positive prostate biopsies for cancer.

The study aims at delivering a second WST09 treatment for the purpose of eradicating the localized prostate cancer.

Multi-centre, phase II, open-label, 12-month clinical trial for patients that previously received a vascular-targeted photodynamic treatment (VTP) with WST09 (Tookad) and still have histological findings (prostate biopsies) indicating the presence of localized cancer.

The WST09-mediated VTP procedure consists of an I.V. infusion of WST09 (Tookad) at 2 mg/kg, in combination with the per-cutaneous interstitial delivery of monochromatic laser light (of a wavelength of 763nm) via the trans-perineal implantation of illumination fibres, positioned in the prostatic lobes.

In a previous Tookad trial, escalating doses of laser light were used with a fixed dose of WST09 (2 mg/kg) in patients with localized prostatic cancer. Patients who underwent the procedure but still have positive prostate biopsies (residual cancer) may benefit from an additional WTS09-mediated VTP procedure. Thus, the aim of this study is to treat patients still presenting with localized prostate cancer with a second WST09-mediated VTP procedure.

Study of WST09 in Prostate Cancer After Radiation: Repeat Procedure

Phase II Study of Photodynamic Therapy With WST09 in Patients With Recurrent or Persistent Localized Carcinoma of the Prostate Following Radiation Therapy Failure - Repeat Procedure

STEBA France

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Study of WST09 in Prostate Cancer After Radiation: Repeat Procedure	NCT00305929	Prostate Cancer	Treatment with ... Treatment with ... Treatment with ...	-	STEBA France
Study of WST09 in Prostate Cancer After Radiation: Repeat Procedure	NCT00305929	Prostate Cancer	Treatment with ... Treatment with ... Treatment with ...	-	STEBA France
Study of WST09 in Prostate Cancer After Radiation: Repeat Procedure	NCT00305929	Prostate Cancer	Treatment with ... Treatment with ... Treatment with ...	-	STEBA France

Spots Global Cancer Trial Database for treatment with tookad vtp