Spots Global Cancer Trial Database for PDT vs Peels for Treatment of Actinic Keratoses
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Trial Identification
Brief Title: PDT vs Peels for Treatment of Actinic Keratoses
Official Title: PDT Versus the Combination of Jessner's Solution and 35% TCA for Treatment of Actinic Keratoses on Upper Extremities: A Randomized Controlled Split-arm Trial
Study ID: NCT04429308
Conditions
Study Description
Brief Summary: The purpose of this study is to to compare photodynamic therapy (PDT) versus the combination of Jessner's solution and 35% trichloroacetic acid (TCA) chemical peels for the treatment of actinic keratoses on upper extremities. This is a randomized clinical trial. Approximately 60 participants with actinic keratoses on both upper arms will be randomized to have one arm receive photodynamic therapy, while the contralateral arm receives Jessner's solution followed immediately by 35% TCA. AKs will be counted before treatment and 2-8 weeks after treatment. This study is a pilot study designed to determine the feasibility of this procedure. Subjects currently living in the Chicago metropolitan area and meet inclusion/exclusion criteria will be considered for enrollment.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: Yes
Locations
Northwestern University Department of Dermatology, Chicago, Illinois, United States
Contact Details
Name: Murad Alam, MD
Affiliation: Northwestern University
Role: PRINCIPAL_INVESTIGATOR
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