Spots Global Cancer Trial Database for Vaccine Immune Recovery After Leukemia
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Trial Identification
Brief Title: Vaccine Immune Recovery After Leukemia
Official Title: A Prospective Cohort Study to Define Infectious Burden, the Seroprevalence of Vaccine Preventable Pathogens and Immune Recovery in the First Year Following Completion of Therapy in Patients With Acute Lymphoblastic Leukemia (ALL)
Study ID: NCT05622682
Conditions
Interventions
Study Description
Brief Summary: This observational study aims to assess recovery of the immune system and immunity to vaccine-preventable diseases in children and adolescents who recently completed treatment for acute lymphoblastic leukemia (ALL). Several children's hospitals in the United States are participating in the study, which will enroll approximately 75 pediatric participants. The study is intended to determine the rate of infection after leukemia treatment and to inform future studies and recommendations about whether children and adolescents who have leukemia should receive additional vaccine doses or boosters after treatment.
Detailed Description:
Eligibility
Minimum Age: 3 Years
Eligible Ages: CHILD, ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, United States
Helen DeVos Children's Hospital, Grand Rapids, Michigan, United States
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States
Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, Tennessee, United States
CHRISTUS Children's (Affiliate of Baylor College of Medicine), San Antonio, Texas, United States
Seattle Children's Hospital, Seattle, Washington, United States
Contact Details
Name: Brian T Fisher, DO MSCE MPH
Affiliation: Children's Hospital of Philadelphia
Role: PRINCIPAL_INVESTIGATOR
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