Spots Global Cancer Trial Database for Enzalutamide With or Without Abiraterone and Prednisone in Treating Patients With Castration-Resistant Metastatic Prostate Cancer
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Trial Identification
Brief Title: Enzalutamide With or Without Abiraterone and Prednisone in Treating Patients With Castration-Resistant Metastatic Prostate Cancer
Official Title: Phase III Trial of Enzalutamide (NSC# 766085) Versus Enzalutamide, Abiraterone and Prednisone for Castration Resistant Metastatic Prostate Cancer
Study ID: NCT01949337
Study Description
Brief Summary: This randomized phase III trial studies enzalutamide to see how well it works compared to enzalutamide, abiraterone, and prednisone in treating patients with castration-resistant metastatic prostate cancer. Androgens can cause the growth of prostate cancer cells. Drugs, such as enzalutamide, abiraterone acetate, and prednisone, may lessen the amount of androgens made by the body.
Detailed Description: Patients are randomized to one of two treatment groups: enzalutamide or enzalutamide, abiraterone and prednisone. Treatment will continue until disease progression or unacceptable toxicity. Patients are followed for clinical outcomes for a maximum of 5 years post study treatment. The primary and secondary objectives are described below. 1. Primary Objective: To compare the overall survival of patients with progressive metastatic castration-resistant prostate cancer (CRPC) treated with either enzalutamide only or enzalutamide with abiraterone and prednisone 2. Secondary Objectives: * To assess the grade 3 or higher toxicity profile and compare safety by treatment arm. * To assess and compare post-treatment prostate-specific antigen (PSA) declines by treatment arm. * To compare radiographic progression free survival defined by Prostate Cancer Working Group 2 (PCWG2), and objective response rate, by treatment arm. * To test for radiographic progression free survival (rPFS) treatment interaction in predicting overall survival. * To assess pre- and post-treatment measures of tumor burden and bone activity using sodium fluoride (NaF) positron emission tomography (PET)/computed tomography (CT) and technetium (Tc) methylene diphosphonate (MDP) bone scintigraphy and correlate these measures with overall survival. * To develop and validate prognostic and predictive models of overall survival that include baseline clinical and molecular markers.
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: MALE
Healthy Volunteers: No
Locations
University of Alabama at Birmingham Cancer Center, Birmingham, Alabama, United States
Southern Cancer Center PC-Providence, Mobile, Alabama, United States
Katmai Oncology Group, Anchorage, Alaska, United States
Providence Alaska Medical Center, Anchorage, Alaska, United States
Mayo Clinic in Arizona, Scottsdale, Arizona, United States
University of Arizona Cancer Center-Orange Grove Campus, Tucson, Arizona, United States
University of Arizona Cancer Center-North Campus, Tucson, Arizona, United States
The University of Arizona Medical Center-University Campus, Tucson, Arizona, United States
Fowler Family Center for Cancer Care, Jonesboro, Arkansas, United States
University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States
Veteran's Administration Medical Center, Little Rock, Arkansas, United States
Kaiser Permanente-Anaheim, Anaheim, California, United States
Kaiser Permanente-Deer Valley Medical Center, Antioch, California, United States
Kaiser Permanente-Baldwin Park, Baldwin Park, California, United States
Kaiser Permanente-Bellflower, Bellflower, California, United States
Alta Bates Summit Medical Center-Herrick Campus, Berkeley, California, United States
Providence Saint Joseph Medical Center/Disney Family Cancer Center, Burbank, California, United States
City of Hope Comprehensive Cancer Center, Duarte, California, United States
Kaiser Permanente Hospital, Fontana, California, United States
Kaiser Permanente-Fremont, Fremont, California, United States
University Oncology Associates, Fresno, California, United States
California Cancer Center - North Fresno, Fresno, California, United States
Kaiser Permanente, Fresno, California, United States
Marin Cancer Care Inc, Greenbrae, California, United States
Kaiser Permanente - Harbor City, Harbor City, California, United States
Kaiser Permanente-Irvine, Irvine, California, United States
UC San Diego Moores Cancer Center, La Jolla, California, United States
Loma Linda University Medical Center, Loma Linda, California, United States
Kaiser Permanente Los Angeles Medical Center, Los Angeles, California, United States
Los Angeles County-USC Medical Center, Los Angeles, California, United States
USC / Norris Comprehensive Cancer Center, Los Angeles, California, United States
Kaiser Permanente-Cadillac, Los Angeles, California, United States
Fremont - Rideout Cancer Center, Marysville, California, United States
Memorial Medical Center, Modesto, California, United States
Kaiser Permanente-Modesto, Modesto, California, United States
USC Norris Oncology/Hematology-Newport Beach, Newport Beach, California, United States
Kaiser Permanente-Oakland, Oakland, California, United States
UC Irvine Health/Chao Family Comprehensive Cancer Center, Orange, California, United States
Palo Alto Medical Foundation Health Care, Palo Alto, California, United States
Kaiser Permanente - Panorama City, Panorama City, California, United States
Feather River Cancer Center, Paradise, California, United States
Kaiser Permanente-Redwood City, Redwood City, California, United States
Kaiser Permanente-Richmond, Richmond, California, United States
Kaiser Permanente-Riverside, Riverside, California, United States
Kaiser Permanente-Roseville, Roseville, California, United States
University of California Davis Comprehensive Cancer Center, Sacramento, California, United States
Kaiser Permanente-South Sacramento, Sacramento, California, United States
Kaiser Permanente - Sacramento, Sacramento, California, United States
Saint Helena Hospital, Saint Helena, California, United States
Kaiser Permanente-San Diego Zion, San Diego, California, United States
Sharp Memorial Hospital, San Diego, California, United States
Naval Medical Center -San Diego, San Diego, California, United States
Veterans Administration-San Diego Medical Center, San Diego, California, United States
Kaiser Permanente-San Francisco, San Francisco, California, United States
UCSF Medical Center-Mount Zion, San Francisco, California, United States
Veterans Affairs Medical Center - San Francisco, San Francisco, California, United States
UCSF Medical Center-Mission Bay, San Francisco, California, United States
Kaiser Permanente-Santa Teresa-San Jose, San Jose, California, United States
Kaiser Permanente San Leandro, San Leandro, California, United States
Kaiser Permanente-San Marcos, San Marcos, California, United States
Kaiser Permanente-San Rafael, San Rafael, California, United States
Kaiser Permanente Medical Center - Santa Clara, Santa Clara, California, United States
Palo Alto Medical Foundation-Santa Cruz, Santa Cruz, California, United States
Kaiser Permanente-Santa Rosa, Santa Rosa, California, United States
Kaiser Permanente-South San Francisco, South San Francisco, California, United States
Saint Joseph's Medical Center, Stockton, California, United States
Kaiser Permanente-Stockton, Stockton, California, United States
Palo Alto Medical Foundation-Sunnyvale, Sunnyvale, California, United States
Kaiser Permanente Medical Center-Vacaville, Vacaville, California, United States
Kaiser Permanente-Vallejo, Vallejo, California, United States
Kaiser Permanente-Walnut Creek, Walnut Creek, California, United States
Kaiser Permanente, Woodland Hills, California, United States
Rocky Mountain Cancer Centers-Boulder, Boulder, Colorado, United States
Memorial Hospital Colorado Springs, Colorado Springs, Colorado, United States
Kaiser Permanente-Franklin, Denver, Colorado, United States
Southwest Oncology PC, Durango, Colorado, United States
The Shaw Regional Cancer Center, Edwards, Colorado, United States
Poudre Valley Hospital, Fort Collins, Colorado, United States
Rocky Mountain Cancer Centers-Lakewood, Lakewood, Colorado, United States
Greenwich Hospital, Greenwich, Connecticut, United States
Smilow Cancer Hospital Care Center at Saint Francis, Hartford, Connecticut, United States
Middlesex Hospital, Middletown, Connecticut, United States
Norwalk Hospital, Norwalk, Connecticut, United States
Eastern Connecticut Hematology and Oncology Associates, Norwich, Connecticut, United States
Stamford Hospital/Bennett Cancer Center, Stamford, Connecticut, United States
Veterans Affairs Connecticut Healthcare System-West Haven Campus, West Haven, Connecticut, United States
Medical Oncology Hematology Consultants PA, Newark, Delaware, United States
MedStar Georgetown University Hospital, Washington, District of Columbia, United States
Sibley Memorial Hospital, Washington, District of Columbia, United States
Veterans Affairs Medical Center -Washington DC, Washington, District of Columbia, United States
Baptist MD Anderson Cancer Center, Jacksonville, Florida, United States
Lakeland Regional Cancer Center, Lakeland, Florida, United States
Mount Sinai Medical Center, Miami Beach, Florida, United States
Florida Hospital Orlando, Orlando, Florida, United States
UF Cancer Center at Orlando Health, Orlando, Florida, United States
Sacred Heart Hospital, Pensacola, Florida, United States
Northside Hospital, Atlanta, Georgia, United States
John B Amos Cancer Center, Columbus, Georgia, United States
Atlanta VA Medical Center, Decatur, Georgia, United States
Medical Center of Central Georgia, Macon, Georgia, United States
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler, Savannah, Georgia, United States
South Georgia Medical Center/Pearlman Cancer Center, Valdosta, Georgia, United States
Hawaii Oncology Inc-Pali Momi, 'Aiea, Hawaii, United States
Pali Momi Medical Center, 'Aiea, Hawaii, United States
Hawaii Cancer Care Inc-POB II, Honolulu, Hawaii, United States
Hawaii Oncology Inc-POB I, Honolulu, Hawaii, United States
Island Urology, Honolulu, Hawaii, United States
Queen's Medical Center, Honolulu, Hawaii, United States
Straub Clinic and Hospital, Honolulu, Hawaii, United States
University of Hawaii Cancer Center, Honolulu, Hawaii, United States
Hawaii Cancer Care Inc-Liliha, Honolulu, Hawaii, United States
Hawaii Oncology Inc-Kuakini, Honolulu, Hawaii, United States
Kuakini Medical Center, Honolulu, Hawaii, United States
Kaiser Permanente Moanalua Medical Center, Honolulu, Hawaii, United States
Tripler Army Medical Center, Honolulu, Hawaii, United States
Wilcox Memorial Hospital and Kauai Medical Clinic, Lihue, Hawaii, United States
Saint Alphonsus Cancer Care Center-Boise, Boise, Idaho, United States
Kootenai Cancer Center, Post Falls, Idaho, United States
Rush - Copley Medical Center, Aurora, Illinois, United States
Illinois CancerCare-Bloomington, Bloomington, Illinois, United States
Mount Sinai Hospital Medical Center, Chicago, Illinois, United States
Northwestern University, Chicago, Illinois, United States
Rush University Medical Center, Chicago, Illinois, United States
Weiss Memorial Hospital, Chicago, Illinois, United States
Advocate Illinois Masonic Medical Center, Chicago, Illinois, United States
Cancer Care Center of Decatur, Decatur, Illinois, United States
Decatur Memorial Hospital, Decatur, Illinois, United States
Crossroads Cancer Center, Effingham, Illinois, United States
NorthShore University HealthSystem-Evanston Hospital, Evanston, Illinois, United States
Illinois CancerCare-Galesburg, Galesburg, Illinois, United States
Northwestern Medicine Cancer Center Delnor, Geneva, Illinois, United States
NorthShore University HealthSystem-Glenbrook Hospital, Glenview, Illinois, United States
Ingalls Memorial Hospital, Harvey, Illinois, United States
NorthShore University HealthSystem-Highland Park Hospital, Highland Park, Illinois, United States
Hines Veterans Administration Hospital, Hines, Illinois, United States
Loyola University Medical Center, Maywood, Illinois, United States
Illinois CancerCare-Peoria, Peoria, Illinois, United States
Quincy Medical Group-Clinic, Quincy, Illinois, United States
West Suburban Medical Center, River Forest, Illinois, United States
OSF Saint Anthony Medical Center, Rockford, Illinois, United States
Central Illinois Hematology Oncology Center, Springfield, Illinois, United States
Southern Illinois University School of Medicine, Springfield, Illinois, United States
Memorial Medical Center, Springfield, Illinois, United States
Carle Cancer Center, Urbana, Illinois, United States
Northwestern Medicine Cancer Center Warrenville, Warrenville, Illinois, United States
Fort Wayne Medical Oncology and Hematology Inc - Jefferson Boulevard, Fort Wayne, Indiana, United States
Fort Wayne Medical Oncology and Hematology Inc-Parkview, Fort Wayne, Indiana, United States
Michiana Hematology Oncology PC-Mishawaka, Mishawaka, Indiana, United States
The Community Hospital, Munster, Indiana, United States
Memorial Hospital of South Bend, South Bend, Indiana, United States
Michiana Hematology Oncology PC-Westville, Westville, Indiana, United States
McFarland Clinic PC-William R Bliss Cancer Center, Ames, Iowa, United States
Hematology Oncology Associates-Quad Cities, Bettendorf, Iowa, United States
Oncology Associates at Mercy Medical Center, Cedar Rapids, Iowa, United States
Medical Oncology and Hematology Associates-West Des Moines, Clive, Iowa, United States
Mercy Cancer Center-West Lakes, Clive, Iowa, United States
Genesis Medical Center - East Campus, Davenport, Iowa, United States
Medical Oncology and Hematology Associates-Laurel, Des Moines, Iowa, United States
Mercy Medical Center - Des Moines, Des Moines, Iowa, United States
University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa, United States
Iowa City VA Healthcare System, Iowa City, Iowa, United States
Mercy Medical Center - North Iowa, Mason City, Iowa, United States
Siouxland Regional Cancer Center, Sioux City, Iowa, United States
Mercy Medical Center-West Lakes, West Des Moines, Iowa, United States
Cancer Center of Kansas - Chanute, Chanute, Kansas, United States
Cancer Center of Kansas - Dodge City, Dodge City, Kansas, United States
Cancer Center of Kansas - El Dorado, El Dorado, Kansas, United States
Newman Regional Health, Emporia, Kansas, United States
Cancer Center of Kansas - Fort Scott, Fort Scott, Kansas, United States
Saint Catherine Hospital, Garden City, Kansas, United States
Saint Rose Ambulatory and Surgery Center, Great Bend, Kansas, United States
Hays Medical Center, Hays, Kansas, United States
Cancer Center of Kansas-Independence, Independence, Kansas, United States
University of Kansas Cancer Center-West, Kansas City, Kansas, United States
University of Kansas Cancer Center, Kansas City, Kansas, United States
Cancer Center of Kansas-Kingman, Kingman, Kansas, United States
Cancer Center of Kansas-Liberal, Liberal, Kansas, United States
Cancer Center of Kansas - Newton, Newton, Kansas, United States
Olathe Medical Center, Olathe, Kansas, United States
Menorah Medical Center, Overland Park, Kansas, United States
University of Kansas Cancer Center-Overland Park, Overland Park, Kansas, United States
Saint Luke's South Hospital, Overland Park, Kansas, United States
Cancer Center of Kansas - Parsons, Parsons, Kansas, United States
Via Christi Hospital-Pittsburg, Pittsburg, Kansas, United States
Cancer Center of Kansas - Pratt, Pratt, Kansas, United States
Cancer Center of Kansas - Salina, Salina, Kansas, United States
Salina Regional Health Center, Salina, Kansas, United States
Saint Francis Hospital and Medical Center - Topeka, Topeka, Kansas, United States
Cancer Center of Kansas - Wellington, Wellington, Kansas, United States
Cancer Center of Kansas-Wichita Medical Arts Tower, Wichita, Kansas, United States
Cancer Center of Kansas - Wichita, Wichita, Kansas, United States
Cancer Center of Kansas - Winfield, Winfield, Kansas, United States
Saint Joseph Hospital East, Lexington, Kentucky, United States
Christus Saint Frances Cabrini Hospital, Alexandria, Louisiana, United States
Hematology/Oncology Clinic LLP, Baton Rouge, Louisiana, United States
Ochsner Health Center-Summa, Baton Rouge, Louisiana, United States
Ochsner Medical Center Kenner, Kenner, Louisiana, United States
East Jefferson General Hospital, Metairie, Louisiana, United States
Tulane University Health Sciences Center, New Orleans, Louisiana, United States
Ochsner Medical Center Jefferson, New Orleans, Louisiana, United States
Harold Alfond Center for Cancer Care, Augusta, Maine, United States
Eastern Maine Medical Center, Bangor, Maine, United States
Lafayette Family Cancer Center-EMMC, Brewer, Maine, United States
Penobscot Bay Medical Center, Rockport, Maine, United States
University of Maryland/Greenebaum Cancer Center, Baltimore, Maryland, United States
Sinai Hospital of Baltimore, Baltimore, Maryland, United States
Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland, United States
Frederick Memorial Hospital, Frederick, Maryland, United States
Montgomery General Hospital-Olney, Olney, Maryland, United States
William E Kahlert Regional Cancer Center/Sinai Hospital, Westminster, Maryland, United States
Tufts Medical Center, Boston, Massachusetts, United States
Simonds-Sinon Regional Cancer Center, Fitchburg, Massachusetts, United States
Newton-Wellesley Hospital, Newton, Massachusetts, United States
Baystate Medical Center, Springfield, Massachusetts, United States
University of Massachusetts Medical School, Worcester, Massachusetts, United States
Saint Joseph Mercy Hospital, Ann Arbor, Michigan, United States
University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, United States
Wayne State University/Karmanos Cancer Institute, Detroit, Michigan, United States
Henry Ford Hospital, Detroit, Michigan, United States
Green Bay Oncology - Escanaba, Escanaba, Michigan, United States
Mercy Health Saint Mary's, Grand Rapids, Michigan, United States
Spectrum Health at Butterworth Campus, Grand Rapids, Michigan, United States
Green Bay Oncology - Iron Mountain, Iron Mountain, Michigan, United States
West Michigan Cancer Center, Kalamazoo, Michigan, United States
Sparrow Hospital, Lansing, Michigan, United States
Saint Mary Mercy Hospital, Livonia, Michigan, United States
Spectrum Health Reed City Hospital, Reed City, Michigan, United States
Saint Mary's of Michigan, Saginaw, Michigan, United States
Munson Medical Center, Traverse City, Michigan, United States
Sanford Clinic North-Bemidgi, Bemidji, Minnesota, United States
Fairview Ridges Hospital, Burnsville, Minnesota, United States
Mercy Hospital, Coon Rapids, Minnesota, United States
Essentia Health Cancer Center, Duluth, Minnesota, United States
Saint Luke's Hospital of Duluth, Duluth, Minnesota, United States
Fairview-Southdale Hospital, Edina, Minnesota, United States
Lake Region Healthcare Corporation-Cancer Care, Fergus Falls, Minnesota, United States
Unity Hospital, Fridley, Minnesota, United States
Mayo Clinic Health Systems-Mankato, Mankato, Minnesota, United States
Minnesota Oncology Hematology PA-Maplewood, Maplewood, Minnesota, United States
Saint John's Hospital - Healtheast, Maplewood, Minnesota, United States
Abbott-Northwestern Hospital, Minneapolis, Minnesota, United States
Hennepin County Medical Center, Minneapolis, Minnesota, United States
Minneapolis Veterans Medical Center, Minneapolis, Minnesota, United States
Health Partners Inc, Minneapolis, Minnesota, United States
Mayo Clinic, Rochester, Minnesota, United States
Coborn Cancer Center at Saint Cloud Hospital, Saint Cloud, Minnesota, United States
Park Nicollet Clinic - Saint Louis Park, Saint Louis Park, Minnesota, United States
Regions Hospital, Saint Paul, Minnesota, United States
Saint Francis Regional Medical Center, Shakopee, Minnesota, United States
Lakeview Hospital, Stillwater, Minnesota, United States
Minnesota Oncology Hematology PA-Woodbury, Woodbury, Minnesota, United States
The West Clinic - Corinth, Corinth, Mississippi, United States
Saint Francis Medical Center, Cape Girardeau, Missouri, United States
Southeast Cancer Center, Cape Girardeau, Missouri, United States
Saint Luke's Hospital, Chesterfield, Missouri, United States
University of Missouri - Ellis Fischel, Columbia, Missouri, United States
Barnes-Jewish West County Hospital, Creve Coeur, Missouri, United States
Capital Region Medical Center-Goldschmidt Cancer Center, Jefferson City, Missouri, United States
Truman Medical Center, Kansas City, Missouri, United States
Saint Luke's Hospital of Kansas City, Kansas City, Missouri, United States
Kansas City Veterans Affairs Medical Center, Kansas City, Missouri, United States
The University of Kansas Cancer Center-South, Kansas City, Missouri, United States
Research Medical Center, Kansas City, Missouri, United States
The University of Kansas Cancer Center-North, Kansas City, Missouri, United States
The University of Kansas Cancer Center-Lee's Summit, Lee's Summit, Missouri, United States
Saint Luke's East - Lee's Summit, Lee's Summit, Missouri, United States
Washington University School of Medicine, Saint Louis, Missouri, United States
Missouri Baptist Medical Center, Saint Louis, Missouri, United States
Mercy Hospital Saint Louis, Saint Louis, Missouri, United States
Mercy Hospital Springfield, Springfield, Missouri, United States
Community Hospital of Anaconda, Anaconda, Montana, United States
Saint Vincent Healthcare, Billings, Montana, United States
Bozeman Deaconess Hospital, Bozeman, Montana, United States
Saint James Community Hospital and Cancer Treatment Center, Butte, Montana, United States
Benefis Healthcare- Sletten Cancer Institute, Great Falls, Montana, United States
Kalispell Regional Medical Center, Kalispell, Montana, United States
CHI Health Saint Francis, Grand Island, Nebraska, United States
CHI Health Good Samaritan, Kearney, Nebraska, United States
Nebraska Hematology and Oncology, Lincoln, Nebraska, United States
Southeast Nebraska Cancer Center, Lincoln, Nebraska, United States
Nebraska Methodist Hospital, Omaha, Nebraska, United States
HealthCare Partners Medical Group Oncology/Hematology-San Martin, Las Vegas, Nevada, United States
HealthCare Partners Medical Group Oncology/Hematology-Tenaya, Las Vegas, Nevada, United States
Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada, United States
Comprehensive Cancer Centers of Nevada - Central Valley, Las Vegas, Nevada, United States
New Hampshire Oncology Hematology PA-Concord, Concord, New Hampshire, United States
Wentworth-Douglass Hospital, Dover, New Hampshire, United States
New Hampshire Oncology Hematology PA-Hooksett, Hooksett, New Hampshire, United States
LRGHealthcare-Lakes Region General Hospital, Laconia, New Hampshire, United States
Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, United States
Norris Cotton Cancer Center-Manchester, Manchester, New Hampshire, United States
Saint Joseph Hospital, Nashua, New Hampshire, United States
Norris Cotton Cancer Center-Nashua, Nashua, New Hampshire, United States
Portsmouth Regional Hospital, Portsmouth, New Hampshire, United States
Memorial Sloan Kettering Cancer Center at Basking Ridge, Basking Ridge, New Jersey, United States
Veterans Adminstration New Jersey Health Care System, East Orange, New Jersey, United States
Hackensack University Medical Center, Hackensack, New Jersey, United States
Virtua Memorial, Mount Holly, New Jersey, United States
The Valley Hospital-Luckow Pavilion, Paramus, New Jersey, United States
Virtua Voorhees, Voorhees, New Jersey, United States
Valley Health System-Hematology/Oncology, Westwood, New Jersey, United States
University of New Mexico Cancer Center, Albuquerque, New Mexico, United States
Memorial Medical Center - Las Cruces, Las Cruces, New Mexico, United States
Christus Saint Vincent Regional Cancer Center, Santa Fe, New Mexico, United States
Montefiore Medical Center-Einstein Campus, Bronx, New York, United States
Montefiore Medical Center - Moses Campus, Bronx, New York, United States
Bronx Veterans Administration Medical Center, Bronx, New York, United States
Kings County Hospital, Brooklyn, New York, United States
Maimonides Medical Center, Brooklyn, New York, United States
Veterans Affairs Western New York Health Care System-Buffalo, Buffalo, New York, United States
Roswell Park Cancer Institute, Buffalo, New York, United States
Memorial Sloan Kettering Cancer Center Commack, Commack, New York, United States
Arnot Ogden Medical Center/Falck Cancer Center, Elmira, New York, United States
Memorial Sloan-Kettering Cancer Center West Harrison, Harrison, New York, United States
North Shore-LIJ Health System/Center for Advanced Medicine, New Hyde Park, New York, United States
Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York, New York, United States
Columbia University/Herbert Irving Cancer Center, New York, New York, United States
Memorial Sloan-Kettering Cancer Center, New York, New York, United States
Weill Medical College of Cornell University, New York, New York, United States
University of Rochester, Rochester, New York, United States
Memorial Sloan Kettering Cancer Center Rockville Centre, Rockville Centre, New York, United States
Memorial Sloan Kettering Cancer Center Sleepy Hollow, Sleepy Hollow, New York, United States
Stony Brook University Medical Center, Stony Brook, New York, United States
State University of New York Upstate Medical University, Syracuse, New York, United States
Syracuse Veterans Administration Medical Center, Syracuse, New York, United States
Randolph Hospital, Asheboro, North Carolina, United States
Cone Health Cancer Center at Alamance Regional, Burlington, North Carolina, United States
UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina, United States
Novant Health Presbyterian Medical Center, Charlotte, North Carolina, United States
Oncology Specialists of Charlotte, Charlotte, North Carolina, United States
Southern Oncology Specialists-Charlotte, Charlotte, North Carolina, United States
Durham Veterans Affairs Medical Center, Durham, North Carolina, United States
Duke University Medical Center, Durham, North Carolina, United States
Wayne Memorial Hospital, Goldsboro, North Carolina, United States
Cone Health Cancer Center, Greensboro, North Carolina, United States
Lake Norman Hematology Oncology Specialists-Huntersville, Huntersville, North Carolina, United States
Southern Oncology Specialists-Huntersville, Huntersville, North Carolina, United States
Novant Health Oncology Specialists-Kernersville, Kernersville, North Carolina, United States
Kinston Medical Specialists PA, Kinston, North Carolina, United States
Novant Health Cancer Specialists-Matthews, Matthews, North Carolina, United States
Lake Norman Hematology Oncology Specialists-Mooresville, Mooresville, North Carolina, United States
Novant Health Oncology Specialists-Mount Airy, Mount Airy, North Carolina, United States
Annie Penn Memorial Hospital, Reidsville, North Carolina, United States
Carolina Oncology Associates PA, Salisbury, North Carolina, United States
Veterans Administration Medical Center, Salisbury, North Carolina, United States
Novant Health Oncology Specialists-Statesville, Statesville, North Carolina, United States
Novant Health Oncology Specialists-Davidson County, Thomasville, North Carolina, United States
Marion L Shepard Cancer Center at Vidant Beaufort Hospital, Washington, North Carolina, United States
Novant Health Oncology Specialists-Wilkesboro, Wilkesboro, North Carolina, United States
Novant Health Forsyth Medical Center, Winston-Salem, North Carolina, United States
Novant Health Oncology Specialists, Winston-Salem, North Carolina, United States
Winston-Salem Health Care, Winston-Salem, North Carolina, United States
Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States
Sanford Bismarck Medical Center, Bismarck, North Dakota, United States
Sanford Clinic North-Fargo, Fargo, North Dakota, United States
Sanford Medical Center-Fargo, Fargo, North Dakota, United States
Altru Cancer Center, Grand Forks, North Dakota, United States
Trinity Cancer Care Center, Minot, North Dakota, United States
Summa Akron City Hospital/Cooper Cancer Center, Akron, Ohio, United States
Summa Barberton Hospital, Barberton, Ohio, United States
UHHS-Chagrin Highlands Medical Center, Beachwood, Ohio, United States
Mercy Medical Center, Canton, Ohio, United States
Dayton Physicians LLC-Miami Valley South, Centerville, Ohio, United States
Geaugra Hospital, Chardon, Ohio, United States
University of Cincinnati/Barrett Cancer Center, Cincinnati, Ohio, United States
Case Western Reserve University, Cleveland, Ohio, United States
MetroHealth Medical Center, Cleveland, Ohio, United States
Cleveland Clinic Cancer Center/Fairview Hospital, Cleveland, Ohio, United States
Cleveland Clinic Foundation, Cleveland, Ohio, United States
Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States
The Mark H Zangmeister Center, Columbus, Ohio, United States
Mount Carmel Health Center West, Columbus, Ohio, United States
Good Samaritan Hospital - Dayton, Dayton, Ohio, United States
Miami Valley Hospital, Dayton, Ohio, United States
Samaritan North Health Center, Dayton, Ohio, United States
Hematology Oncology Center Incorporated, Elyria, Ohio, United States
Mercy Cancer Center-Elyria, Elyria, Ohio, United States
Armes Family Cancer Center, Findlay, Ohio, United States
Blanchard Valley Hospital, Findlay, Ohio, United States
Orion Cancer Care, Findlay, Ohio, United States
Cleveland Clinic Cancer Center Independence, Independence, Ohio, United States
Greater Dayton Cancer Center, Kettering, Ohio, United States
Cleveland Clinic Cancer Center Mansfield, Mansfield, Ohio, United States
Toledo Clinic Cancer Centers-Maumee, Maumee, Ohio, United States
Hillcrest Hospital Cancer Center, Mayfield Heights, Ohio, United States
Ireland Cancer Center Landerbrook Health Center, Mayfield Heights, Ohio, United States
Summa Health Center at Lake Medina, Medina, Ohio, United States
Lake University Ireland Cancer Center, Mentor, Ohio, United States
Southwest General Health Center Ireland Cancer Center, Middleburg Heights, Ohio, United States
University Hospitals Parma Medical Center, Parma, Ohio, United States
Southern Ohio Medical Center, Portsmouth, Ohio, United States
Ireland Cancer Center at Firelands Regional Medical Center, Sandusky, Ohio, United States
North Coast Cancer Care, Sandusky, Ohio, United States
Cleveland Clinic Cancer Center Strongsville, Strongsville, Ohio, United States
University of Toledo, Toledo, Ohio, United States
Toledo Clinic Cancer Centers-Toledo, Toledo, Ohio, United States
University Hospitals Sharon Health Center, Wadsworth, Ohio, United States
South Pointe Hospital, Warrensville Heights, Ohio, United States
University Pointe, West Chester, Ohio, United States
Saint Ann's Hospital, Westerville, Ohio, United States
UH-Seidman Cancer Center at Saint John Medical Center, Westlake, Ohio, United States
UHHS-Westlake Medical Center, Westlake, Ohio, United States
Cleveland Clinic Wooster Family Health and Surgery Center, Wooster, Ohio, United States
Wright-Patterson Medical Center, Wright-Patterson Air Force Base, Ohio, United States
Cancer Centers of Southwest Oklahoma Research, Lawton, Oklahoma, United States
University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States
Mercy Hospital Oklahoma City, Oklahoma City, Oklahoma, United States
Oklahoma Cancer Specialists and Research Institute-Tulsa, Tulsa, Oklahoma, United States
Good Samaritan Hospital, Corvallis, Oregon, United States
Providence Milwaukie Hospital, Milwaukie, Oregon, United States
Providence Newberg Medical Center, Newberg, Oregon, United States
Providence Willamette Falls Medical Center, Oregon City, Oregon, United States
Legacy Good Samaritan Hospital and Medical Center, Portland, Oregon, United States
Providence Portland Medical Center, Portland, Oregon, United States
Providence Saint Vincent Medical Center, Portland, Oregon, United States
Kaiser Permanente Northwest, Portland, Oregon, United States
Abington Memorial Hospital, Abington, Pennsylvania, United States
Lehigh Valley Hospital-Cedar Crest, Allentown, Pennsylvania, United States
Lehigh Valley Hospital - Muhlenberg, Bethlehem, Pennsylvania, United States
Geisinger Medical Center, Danville, Pennsylvania, United States
Adams Cancer Center, Gettysburg, Pennsylvania, United States
Saint Mary Medical and Regional Cancer Center, Langhorne, Pennsylvania, United States
Allegheny Valley Hospital, Natrona Heights, Pennsylvania, United States
Allegheny General Hospital, Pittsburgh, Pennsylvania, United States
University of Pittsburgh Cancer Institute (UPCI), Pittsburgh, Pennsylvania, United States
WellSpan Health-York Hospital, York, Pennsylvania, United States
Roger Williams Medical Center, Providence, Rhode Island, United States
Roper Hospital, Charleston, South Carolina, United States
Charleston Hematology Oncology Associates-Roper, Charleston, South Carolina, United States
Lowcountry Hematology Oncology PA-North Charleston, Charleston, South Carolina, United States
Bon Secours Saint Francis Hospital, Charleston, South Carolina, United States
Charleston Hematology Oncology Associates PA-St. Francis, Charleston, South Carolina, United States
Lowcountry Hematology Oncology PA-West Ashley, Charleston, South Carolina, United States
Greenville Health System Cancer Institute-Easley, Easley, South Carolina, United States
Saint Francis Hospital, Greenville, South Carolina, United States
Greenville Health System Cancer Institute-Butternut, Greenville, South Carolina, United States
Greenville Health System Cancer Institute-Faris, Greenville, South Carolina, United States
Saint Francis Cancer Center, Greenville, South Carolina, United States
Greenville Health System Cancer Institute-Eastside, Greenville, South Carolina, United States
Greenville Health System Cancer Institute-Greer, Greer, South Carolina, United States
Carolina Blood and Cancer Care Associates PA-Lancaster, Lancaster, South Carolina, United States
Lowcountry Hematology Oncology PA-Mount Pleasant, Mount Pleasant, South Carolina, United States
Greenville Health System Cancer Institute-Seneca, Seneca, South Carolina, United States
Greenville Health System Cancer Institute-Spartanburg, Spartanburg, South Carolina, United States
Avera Cancer Institute-Aberdeen, Aberdeen, South Dakota, United States
Rapid City Regional Hospital, Rapid City, South Dakota, United States
Sanford Cancer Center-Oncology Clinic, Sioux Falls, South Dakota, United States
Avera Cancer Institute, Sioux Falls, South Dakota, United States
The West Clinic - Wolf River, Germantown, Tennessee, United States
University of Tennessee Health Science Center, Memphis, Tennessee, United States
Parkland Memorial Hospital, Dallas, Texas, United States
UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas, United States
UT Southwestern/Simmons Cancer Center-Fort Worth, Fort Worth, Texas, United States
University of Texas Medical Branch, Galveston, Texas, United States
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston, Texas, United States
Ben Taub General Hospital, Houston, Texas, United States
UTMB Cancer Center at Victory Lakes, League City, Texas, United States
University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States
University of Vermont College of Medicine, Burlington, Vermont, United States
White River Junction Veteran Administration Medical Center, White River Junction, Vermont, United States
University of Virginia Cancer Center, Charlottesville, Virginia, United States
Virginia Oncology Associates-Hampton, Hampton, Virginia, United States
Lynchburg Hematology-Oncology Clinic, Lynchburg, Virginia, United States
Memorial Hospital Of Martinsville, Martinsville, Virginia, United States
Bon Secours Memorial Regional Medical Center, Mechanicsville, Virginia, United States
Bon Secours Saint Francis Medical Center, Midlothian, Virginia, United States
Virginia Cancer Institute, Richmond, Virginia, United States
Virginia Commonwealth University/Massey Cancer Center, Richmond, Virginia, United States
Shenandoah Oncology Associates PC, Winchester, Virginia, United States
PeaceHealth Saint Joseph Medical Center, Bellingham, Washington, United States
Providence Regional Cancer Partnership, Everett, Washington, United States
Swedish Cancer Institute-Issaquah, Issaquah, Washington, United States
Harrison HealthPartners Hematology and Oncology-Poulsbo, Poulsbo, Washington, United States
Minor and James Medical PLLC, Seattle, Washington, United States
Swedish Medical Center-First Hill, Seattle, Washington, United States
West Virginia University Charleston, Charleston, West Virginia, United States
Saint Mary's Medical Center, Huntington, West Virginia, United States
Langlade Hospital and Cancer Center, Antigo, Wisconsin, United States
Aurora Cancer Care-Southern Lakes VLCC, Burlington, Wisconsin, United States
Marshfield Clinic Cancer Center at Sacred Heart, Eau Claire, Wisconsin, United States
Mayo Clinic Health System-Eau Claire Clinic, Eau Claire, Wisconsin, United States
Sacred Heart Hospital, Eau Claire, Wisconsin, United States
Saint Agnes Hospital/Agnesian Cancer Center, Fond Du Lac, Wisconsin, United States
Aurora Health Care Germantown Health Center, Germantown, Wisconsin, United States
Aurora Cancer Care-Grafton, Grafton, Wisconsin, United States
Green Bay Oncology at Saint Vincent Hospital, Green Bay, Wisconsin, United States
Saint Vincent Hospital Cancer Center Green Bay, Green Bay, Wisconsin, United States
Green Bay Oncology Limited at Saint Mary's Hospital, Green Bay, Wisconsin, United States
Saint Vincent Hospital Cancer Center at Saint Mary's, Green Bay, Wisconsin, United States
Aurora BayCare Medical Center, Green Bay, Wisconsin, United States
Mercy Health System, Janesville, Wisconsin, United States
Aurora Cancer Care-Kenosha South, Kenosha, Wisconsin, United States
Gundersen Lutheran Medical Center, La Crosse, Wisconsin, United States
William S Middleton VA Medical Center, Madison, Wisconsin, United States
University of Wisconsin Hospital and Clinics, Madison, Wisconsin, United States
Holy Family Memorial Hospital, Manitowoc, Wisconsin, United States
Vince Lombardi Cancer Clinic-Marinette, Marinette, Wisconsin, United States
Marshfield Clinic, Marshfield, Wisconsin, United States
Saint Joseph's Hospital, Marshfield, Wisconsin, United States
Aurora Cancer Care-Milwaukee, Milwaukee, Wisconsin, United States
Aurora Saint Luke's Medical Center, Milwaukee, Wisconsin, United States
Froedtert and the Medical College of Wisconsin, Milwaukee, Wisconsin, United States
Aurora Sinai Medical Center, Milwaukee, Wisconsin, United States
Zablocki Veterans Administration Medical Center, Milwaukee, Wisconsin, United States
Marshfield Clinic-Minocqua Center, Minocqua, Wisconsin, United States
ProHealth D N Greenwald Center, Mukwonago, Wisconsin, United States
ProHealth Oconomowoc Memorial Hospital, Oconomowoc, Wisconsin, United States
Green Bay Oncology - Oconto Falls, Oconto Falls, Wisconsin, United States
Vince Lombardi Cancer Clinic - Oshkosh, Oshkosh, Wisconsin, United States
Wheaton Franciscan Cancer Care - All Saints, Racine, Wisconsin, United States
Aurora Cancer Care-Racine, Racine, Wisconsin, United States
Marshfield Clinic-Rice Lake Center, Rice Lake, Wisconsin, United States
HSHS Saint Nicholas Hospital, Sheboygan, Wisconsin, United States
Vince Lombardi Cancer Clinic-Sheboygan, Sheboygan, Wisconsin, United States
Marshfield Clinic Cancer Care at Saint Michael's Hospital, Stevens Point, Wisconsin, United States
Saint Michael's Hospital, Stevens Point, Wisconsin, United States
Green Bay Oncology - Sturgeon Bay, Sturgeon Bay, Wisconsin, United States
Aurora Medical Center in Summit, Summit, Wisconsin, United States
Vince Lombardi Cancer Clinic-Two Rivers, Two Rivers, Wisconsin, United States
Aurora Cancer Care-Waukesha, Waukesha, Wisconsin, United States
ProHealth Waukesha Memorial Hospital, Waukesha, Wisconsin, United States
Aspirus Regional Cancer Center, Wausau, Wisconsin, United States
Aurora Cancer Care-Milwaukee West, Wauwatosa, Wisconsin, United States
Aurora West Allis Medical Center, West Allis, Wisconsin, United States
Diagnostic and Treatment Center, Weston, Wisconsin, United States
Marshfield Clinic - Weston Center, Weston, Wisconsin, United States
Aspirus UW Cancer Center, Wisconsin Rapids, Wisconsin, United States
Cross Cancer Institute, Edmonton, Alberta, Canada
BCCA-Vancouver Cancer Centre, Vancouver, British Columbia, Canada
The Moncton Hospital, Moncton, New Brunswick, Canada
The Vitalite Health Network - Dr Leon Richard Oncology Centre, Moncton, New Brunswick, Canada
Atlantic Health Sciences Corporation-Saint John Regional Hospital, Saint John, New Brunswick, Canada
Doctor H. Bliss Murphy Cancer Centre, St. John's, Newfoundland and Labrador, Canada
Cambridge Memorial Hospital, Cambridge, Ontario, Canada
Grand River Regional Cancer Centre at Grand River Hospital, Kitchener, Ontario, Canada
Allan Blair Cancer Centre, Regina, Saskatchewan, Canada
San Juan Veterans Affairs Medical Center, San Juan, , Puerto Rico
Fundacion De Investigacion de Diego, San Juan, , Puerto Rico
San Juan City Hospital, San Juan, , Puerto Rico
Contact Details
Name: Michael Morris, M.D.
Affiliation: Memorial Sloan Kettering Cancer Center
Role: STUDY_CHAIR
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