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Spots Global Cancer Trial Database for enzalutamide

Every month we try and update this database with for enzalutamide cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study titleNCT IDConditionsInterventionsEligibilityOrganizationLink
Enzalutamide and Cabazitaxel in Treating Patients With Metastatic, Castration-Resistant Prostate CancerNCT02522715
Castration-Resi...
Metastatic Pros...
Recurrent Prost...
Stage IV Prosta...
Cabazitaxel
Enzalutamide
Laboratory Biom...
Pharmacological...
Prednisone
18 Years - OHSU Knight Cancer Institute
Docetaxel/Prednisone Versus Docetaxel/Prednisone and Enzalutamide in Castration-Resistant Prostate CancerNCT02685267
Prostate Cancer
Docetaxel
Enzalutamide
Prednisone
18 Years - Prostate Cancer Clinical Trials Consortium
Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)NCT06136624
Prostate Cancer...
Opevesostat
Abiraterone ace...
Enzalutamide
Hydrocortisone
Fludrocortisone...
Prednisone
Dexamethasone
- Merck Sharp & Dohme LLC
A Study for Subjects With Prostate Cancer Who Previously Participated in an Enzalutamide Clinical StudyNCT02960022
Prostate Cancer
enzalutamide
abiraterone ace...
prednisone
18 Years - Astellas Pharma Inc
A Study Using Available Data to Learn to What Extent Patients With Prostate Cancer Who Received Second Generation Androgen Receptor Inhibitors Took Their Medication as Prescribed or Stopped Taking Their Medication CompletelyNCT05202301
Prostate Cancer
Darolutamide (N...
Enzalutamide
Apalutamide
18 Years - Bayer
Abiraterone, Enzalutamide, or Apalutamide in Castrate-sensitive Prostate Cancer.NCT05422911
Metastatic Canc...
Neoplasm, Prost...
Abiraterone ace...
Apalutamide
Enzalutamide
- James J. Peters Veterans Affairs Medical Center
Enzalutamide Plus Talazoparib for the Treatment of Hormone Sensitive Prostate Cancer (ZZ-First)NCT04332744
Metastatic Pros...
Enzalutamide
Talazoparib
18 Years - MedSIR
a Vigibase Pharmacovigilance Study of ENzalutamide Drug-induced neurotoxicitYNCT04290611
Prostate Cancer
Neuropathy
Epilepsy
Encephalopathy
Enzalutamide
18 Years - 100 YearsGroupe Hospitalier Pitie-Salpetriere
Real-World Study of Enzalutamide and Abiraterone Acetate (With Prednisone) TolerabilityNCT02663193
Prostate Cancer
No Intervention
18 Years - Janssen Scientific Affairs, LLC
Relative Bioavailability Study of Enzalutamide in Prostate Cancer PatientsNCT01902251
Prostate Cancer
Pharmacokinetic...
Enzalutamide ta...
Enzalutamide ca...
18 Years - Astellas Pharma Inc
Salvage Therapeutic Radiation With Enzalutamide and ADT in Men With Recurrent Prostate Cancer (STREAM)NCT02057939
Prostate Cancer
enzalutamide
Androgen Depriv...
Radiation Thera...
18 Years - Duke University
Evaluation of Safety and Efficacy of KPG-121 Plus Enzalutamide, Abiraterone or Apalutamide in CRPC PatientsNCT03569280
Castration-Resi...
Enzalutamide or...
18 Years - Kangpu Biopharmaceuticals, Ltd.
A Study to Assess the Safety of Continued Administration of MDV3100 in Subjects With Prostate Cancer Who Showed Benefit From Prior Exposure to MDV3100NCT01534052
Castration-Resi...
Enzalutamide
18 Years - Astellas Pharma Inc
Enzalutamide vs. Abiraterone in Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer (mCRPC)NCT05520138
Prostatic Neopl...
Enzalutamide
Abiraterone ace...
18 Years - Pfizer
Luteinizing Hormone-releasing Hormone Analogue and Enzalutamide +/- Zoledronic Acid in Prostate Cancer PatientsNCT03336983
Prostate Cancer
Bone Metastases
Zoledronic Acid
Enzalutamide
18 Years - Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Using Multiparametric MRI to Evaluate Intraprostatic Tumor Responses and Androgen Resistance Patterns in Newly Diagnosed Prostate CancerNCT02430480
Prostate Cancer
Goserelin
Enzalutamide
mpMRI
18 Years - National Institutes of Health Clinical Center (CC)
Study of Talazoparib With Enzalutamide in Men With DDR Gene Mutated mCSPCNCT04821622
Prostate Cancer
talazoparib plu...
Placebo plus en...
18 Years - Pfizer
Determine Effect of Enzalutamide (MDV3100) on the Androgen Signaling Pathway in Correlation With the Anti-tumor Effects of EnzalutamideNCT01091103
Metastatic Prog...
Enzalutamide
18 Years - Pfizer
Efficacy and Safety of Pembrolizumab (MK-3475) Plus Enzalutamide Plus Androgen Deprivation Therapy (ADT) Versus Placebo Plus Enzalutamide Plus ADT in Participants With Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) (MK-3475-991/KEYNOTE-991)NCT04191096
Metastatic Horm...
Pembrolizumab
Enzalutamide
Androgen Depriv...
Placebo
18 Years - Merck Sharp & Dohme LLC
Cabazitaxel vs Abiraterone or Enzalutamide in Patients With Poor Prognosis Metastatic Castration-resistant Prostate CancerNCT02254785
Metastatic Cast...
cabazitaxel
Abiraterone
Enzalutamide 16...
18 Years - British Columbia Cancer Agency
Study of Enzalutamide With and Without Sorafenib in Advanced Hepatocellular Carcinoma PatientsNCT02642913
Hepatocellular ...
Enzalutamide
Enzalutamide wi...
18 Years - Memorial Sloan Kettering Cancer Center
Genetic and Molecular Mechanisms in Assessing Response in Patients With Prostate Cancer Receiving Enzalutamide TherapyNCT02099864
Castration-Resi...
Metastatic Mali...
Metastatic Mali...
Metastatic Pros...
Recurrent Prost...
Stage III Prost...
Stage IV Prosta...
Enzalutamide
18 Years - OHSU Knight Cancer Institute
A Randomized Phase IIa Efficacy and Safety Study of Radium-223 Dichloride With Abiraterone Acetate or Enzalutamide in Metastatic Castration-resistant Prostate Cancer (CRPC)NCT02034552
Prostatic Neopl...
Radium-223 dich...
Abiraterone ace...
Prednisone
Enzalutamide
18 Years - Bayer
Study of Abiraterone Acetate or Enzalutamide, Atezolizumab, GnRH Analog and Radiation Therapy in Men With Newly Diagnosed Hormone-sensitive Prostate CancerNCT04262154
Metastatic Pros...
Atezolizumab
Abiraterone
Prednisone
GnRH analog
Stereotactic Bo...
Enzalutamide
Follow up
18 Years - Memorial Sloan Kettering Cancer Center
Enzalutamide in Androgen Deprivation Therapy With Radiation Therapy for High Risk, Clinically Localised, Prostate CancerNCT02446444
Prostatic Neopl...
Enzalutamide
Conventional NS...
LHRHA
External Beam R...
18 Years - University of Sydney
Docetaxel/Prednisone Versus Docetaxel/Prednisone and Enzalutamide in Castration-Resistant Prostate CancerNCT02685267
Prostate Cancer
Docetaxel
Enzalutamide
Prednisone
18 Years - Prostate Cancer Clinical Trials Consortium
Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid TumorsNCT04557449
Liposarcoma
CRC
Prostate Cancer
Breast Neoplasm...
Adenocarcinoma ...
Solid Tumors
PF-07220060
Letrozole
Fulvestrant
Midazolam
Enzalutamide
18 Years - Pfizer
Study on Enzalutamide and Flutamide in Patients With Castration Resistant Prostate CancerNCT02918968
Prostate Cancer
Enzalutamide
Flutamide
Androgen depriv...
20 Years - Astellas Pharma Inc
Dexamethasone Prior to Re-treatment With Enzalutamide in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer Previously Treated With Enzalutamide and DocetaxelNCT02491411
Hormone-Resista...
Metastatic Pros...
Prostate Adenoc...
Stage IV Prosta...
Dexamethasone
Enzalutamide
Laboratory Biom...
Quality-of-Life...
18 Years - Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Pan Tumor Rollover StudyNCT03899155
Cancer
Nivolumab
Ipilimumab
Cabozantinib
Trametinib
Relatlimab
Nivolumab + Rel...
Capecitabine
Bevacizumab
Temozolomide
Rucaparib
Daratumumab
Regorafinib
Leucovorin
Fluorouracil
Oxaliplatin
Enzalutamide
Sunitinib
Pemetrexed
Pembrolizumab
18 Years - Bristol-Myers Squibb
Pan Tumor Rollover StudyNCT03899155
Cancer
Nivolumab
Ipilimumab
Cabozantinib
Trametinib
Relatlimab
Nivolumab + Rel...
Capecitabine
Bevacizumab
Temozolomide
Rucaparib
Daratumumab
Regorafinib
Leucovorin
Fluorouracil
Oxaliplatin
Enzalutamide
Sunitinib
Pemetrexed
Pembrolizumab
18 Years - Bristol-Myers Squibb
A Study of JNJ-78278343 in Combination With Either JNJ-63723283 (Cetrelimab), Taxane Chemotherapy, or Androgen Receptor Pathway Inhibitors for Metastatic Castration-Resistant Prostate CancerNCT05818683
Metastatic Cast...
JNJ-78278343
Cetrelimab
Cabazitaxel
Docetaxel
Apalutamide
Enzalutamide
Darolutamide
Abiraterone ace...
18 Years - Janssen Research & Development, LLC
Vudalimab (XmAb20717) in Combination With Standard of Care Treatment in Patients With Metastatic Castration Sensitive Prostate CancerNCT05733351
Castration-Sens...
Metastatic Pros...
Stage IVB Prost...
Abiraterone
Biospecimen Col...
Bone Scan
Computed Tomogr...
Docetaxel
Enzalutamide
FDG-Positron Em...
Magnetic Resona...
PSMA PET Scan
Vudalimab
18 Years - Emory University
Safety and Efficacy Study of Enzalutamide in Patients With Advanced, Androgen Receptor-Positive, Triple Negative Breast CancerNCT01889238
Advanced, Andro...
Enzalutamide
18 Years - Pfizer
A Study for the Participants With Metastatic Hormone Sensitive Prostate Cancer (mHSPC) Treated With Androgen Deprivation Therapy (ADT) Plus Apalutamide or EnzalutamideNCT05901649
Metastatic Horm...
Apalutamide
Enzalutamide
18 Years - Janssen-Cilag Ltd.
A Study to Evaluate the Effect of Multiple Doses of Enzalutamide on the Pharmacokinetics of Substrates of P-glycoprotein (Digoxin) and Breast Cancer Resistant Protein (Rosuvastatin) in Male Subjects With Prostate CancerNCT04094519
Prostate Cancer
enzalutamide
enzalutamide Pl...
digoxin
rosuvastatin
18 Years - Astellas Pharma Inc
Docetaxel/Prednisone Versus Docetaxel/Prednisone and Enzalutamide in Castration-Resistant Prostate CancerNCT02685267
Prostate Cancer
Docetaxel
Enzalutamide
Prednisone
18 Years - Prostate Cancer Clinical Trials Consortium
An Extension Study in Participants Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Atezolizumab Study (IMbrella C)NCT05112965
Neoplasms
Atezolizumab
Bevacizumab
Pemetrexed
Paclitaxel
Enzalutamide
18 Years - Hoffmann-La Roche
Study of Olaparib (Lynparza™) Versus Enzalutamide or Abiraterone Acetate in Men With Metastatic Castration-Resistant Prostate Cancer (PROfound Study)NCT02987543
Metastatic Cast...
olaparib
enzalutamide
abiraterone ace...
abiraterone ace...
enzalutamide
18 Years - 130 YearsAstraZeneca
Study of SX-682 Plus Enzalutamide in Men With Abiraterone-Resistant Metastatic Castration Resistant Prostate CancerNCT06228053
Metastatic Cast...
SX-682
Enzalutamide
18 Years - Syntrix Biosystems, Inc.
Androgen Receptor Directed Therapy on Cognitive Function in Patients Treated With Darolutamide or EnzalutamideNCT04335682
Metastatic Pros...
Prostate Cancer...
Prostate Cancer
Castrate Resist...
Darolutamide
Enzalutamide
18 Years - Alliance Foundation Trials, LLC.
Study of NUV-422 in Combination With Enzalutamide in Patients With mCRPCNCT05191017
Prostate Cancer
Prostatic Cance...
Cancer of Prost...
Cancer of the P...
Prostate Neopla...
Castrate Resist...
Castration Resi...
Castration Resi...
NUV-422
Enzalutamide
18 Years - Nuvation Bio Inc.
Enzalutamide Implants (Enolen) in Patients With Prostate CancerNCT06257693
Prostate Adenoc...
enzalutamide
21 Years - Alessa Therapeutics Inc.
A Study of Sipuleucel-T With Administration of Enzalutamide in Men With Metastatic Castrate-Resistant Prostate CancerNCT01981122
Metastatic Pros...
sipuleucel-T
enzalutamide
18 Years - Dendreon
A Phase II Study of AAA617 Alone and AAA617 in Combination With ARPI in Patients With PSMA PET Scan Positive CRPCNCT05849298
Prostatic Neopl...
AAA617
AAA517
Piflufolastat F...
ARPI
ADT
Best supportive...
18 Years - Novartis
Study Evaluating mCRPC Treatment Using PSMA [Lu-177]-PNT2002 Therapy After Second-line Hormonal TreatmentNCT04647526
Metastatic Cast...
[Lu-177]-PNT200...
Abiraterone
Enzalutamide
18 Years - POINT Biopharma, a wholly owned subsidiary of Eli Lilly and Company
Dynamics of Androgen Receptor Genomics and Transcriptomics After Neoadjuvant Androgen AblationNCT03297385
Prostate Cancer
DNA
Androgen Recept...
Enzalutamide
18 Years - The Netherlands Cancer Institute
Efficacy and Safety of Pembrolizumab (MK-3475) Plus Enzalutamide Plus Androgen Deprivation Therapy (ADT) Versus Placebo Plus Enzalutamide Plus ADT in Participants With Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) (MK-3475-991/KEYNOTE-991)-China ExtensionNCT04934722
Metastatic Horm...
Pembrolizumab
Enzalutamide
Androgen Depriv...
Placebo
18 Years - Merck Sharp & Dohme LLC
A Phase II Study of AAA617 Alone and AAA617 in Combination With ARPI in Patients With PSMA PET Scan Positive CRPCNCT05849298
Prostatic Neopl...
AAA617
AAA517
Piflufolastat F...
ARPI
ADT
Best supportive...
18 Years - Novartis
Enzalutamide for Patients With Androgen Receptor Positive Salivary CancersNCT02749903
Salivary Cancer
enzalutamide
18 Years - Alliance for Clinical Trials in Oncology
Crizotinib in Combination With Enzalutamide in Metastatic Castration-resistant Prostate CancerNCT02207504
Castration-resi...
Crizotinib
Enzalutamide
18 Years - Dana-Farber Cancer Institute
Study of Pembrolizumab (MK-3475) Plus Olaparib Versus Abiraterone Acetate or Enzalutamide in Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-7339-010/KEYLYNK-010)NCT03834519
Prostatic Neopl...
Pembrolizumab
Olaparib
Abiraterone ace...
Prednisone
Enzalutamide
Prednisolone
18 Years - Merck Sharp & Dohme LLC
A Study for Subjects With Prostate Cancer Who Previously Participated in an Enzalutamide Clinical StudyNCT02960022
Prostate Cancer
enzalutamide
abiraterone ace...
prednisone
18 Years - Astellas Pharma Inc
A Study to Monitor the Safety of Enzalutamide in Patients With Progressive Castration-Resistant Prostate Cancer Previously Treated With Docetaxel-Based ChemotherapyNCT02124668
Castration-Resi...
Prostate Cancer
Enzalutamide
- Astellas Pharma Inc
A Study of Sipuleucel-T With Administration of Enzalutamide in Men With Metastatic Castrate-Resistant Prostate CancerNCT01981122
Metastatic Pros...
sipuleucel-T
enzalutamide
18 Years - Dendreon
Study to Compare the Effects of Drug Darolutamide and Drug Enzalutamide on Physical Function, Including Balance and Daily Activity, in Patients With Castration-resistant Prostate Cancer (CRPC)NCT04157088
Prostatic Cance...
Darolutamide (N...
Enzalutamide
18 Years - Bayer
A Study of Enzalutamide Versus Bicalutamide in Castrate Men With Metastatic Prostate CancerNCT01288911
Prostatic Neopl...
enzalutamide
bicalutamide
18 Years - Astellas Pharma Inc
Use of an Experimental Drug, CC-115, With Enzalutamide in Men With Castration-Resistant Prostate CancerNCT02833883
Prostate Cancer
Castration Resi...
Enzalutamide
CC-115
18 Years - Memorial Sloan Kettering Cancer Center
Determine Effect of Enzalutamide (MDV3100) on the Androgen Signaling Pathway in Correlation With the Anti-tumor Effects of EnzalutamideNCT01091103
Metastatic Prog...
Enzalutamide
18 Years - Pfizer
Enzalutamide With Ribociclib in Treating Patients With Metastatic Castrate-Resistant, Chemotherapy Naive Prostate Cancer That Retains Retinoblastoma ExpressionNCT02555189
Castration-Resi...
Metastatic Pros...
Prostate Carcin...
Stage IV Prosta...
Enzalutamide
Ribociclib
Laboratory Biom...
Pharmacological...
Biospecimen Col...
Biopsy
Echocardiograph...
Multigated Acqu...
Bone Scan
Computed Tomogr...
Magnetic Resona...
18 Years - Thomas Jefferson University
Continuation Protocol for ZEN003694 in Patients Experiencing Clinical Benefit While Enrolled in a ZEN003694 ProtocolNCT04145375
mCRPC
ZEN003694
Enzalutamide
18 Years - Zenith Epigenetics
Decitabine/Cedazuridine and Enzalutamide for the Treatment of Metastatic Castrate Resistant Prostate CancerNCT05037500
Castration-Resi...
Stage IV Prosta...
Stage IVA Prost...
Stage IVB Prost...
Decitabine and ...
Enzalutamide
18 Years - Roswell Park Cancer Institute
Safety and Tolerability Study of MDV3100 in Combination With Docetaxel in Men With Advanced Prostate CancerNCT01565928
Prostate Cancer
MDV3100
18 Years - Pfizer
Evaluation of Fapi-pet in Prostate Cancer.NCT05192694
Prostate Cancer
Computed tomogr...
18 Years - 100 YearsHelsinki University Central Hospital
A Study for the Participants With Metastatic Hormone Sensitive Prostate Cancer (mHSPC) Treated With Androgen Deprivation Therapy (ADT) Plus Apalutamide or EnzalutamideNCT05901649
Metastatic Horm...
Apalutamide
Enzalutamide
18 Years - Janssen-Cilag Ltd.
Outcomes of Local Treatment for Oligometastatic Prostate Cancer Diagnosed Using PSMA PET Imaging: OLIGOMET StudyNCT06430411
Prostate Cancer...
Prostate Cancer...
Prostate Cancer
Prostate Neopla...
Oligometastatic...
Oligometastasis
Radical prostat...
Prostate irradi...
Surgical metast...
Irradiation of ...
Abiraterone ace...
Enzalutamide
Darolutamide
Apalutamide
Docetaxel
Lutetium-PSMA
Androgen depriv...
18 Years - 80 YearsMedical University of Vienna
Enzalutamide in First Line Androgen Deprivation Therapy for Metastatic Prostate CancerNCT02446405
Prostatic Neopl...
Enzalutamide
NSAA
LHRHA or Surgic...
18 Years - University of Sydney
A Registry Based Study Evaluating Overall Survival and Treatment Length in mCRPC Patients Treated With Enzalutamide in SwedenNCT03328364
Metastatic Cast...
enzalutamide
docetaxel
18 Years - Astellas Pharma Inc
Safety and Efficacy Study of Enzalutamide Plus Leuprolide in Patients With Nonmetastatic Prostate Cancer (EMBARK)NCT02319837
Hormone Sensiti...
Prostate Cancer
Cancer of the P...
Enzalutamide
Placebo (No lon...
Leuprolide Open...
18 Years - Pfizer
A Multi-centre Study to Assess the Safety, Tolerability, and Pharmacokinetics of Capivasertib (AZD5363) in Combination With Novel Agents in Patients With Metastatic Prostate CancerNCT04087174
Prostate Cancer
Capivasertib
Enzalutamide
Abiraterone
18 Years - 130 YearsAstraZeneca
Real World Evidence Study on Metastatic Prostate Cancer in the Pirkanmaa Hospital District in FinlandNCT05701007
Metastatic Cast...
Metastatic Cast...
abiraterone
enzalutamide
docetaxel
apalutamide
cabazitaxel
Radium-223
Lutetium-177
degarelix
goserelin
leuprorelin
triptorelin
18 Years - Pfizer
A Safety and Efficacy Study of Oral MDV3100 in Chemotherapy-Naive Patients With Progressive Metastatic Prostate CancerNCT01212991
Prostate Cancer
Enzalutamide
Placebo
18 Years - Pfizer
Denosumab Plus Enzalutamide, Abiraterone and Prednisone Compared to Denosumab Plus Enzalutamide Alone for Men With Castrate Resistant Prostate Cancer (CRPC) With Bone MetastasesNCT02758132
Prostate Cancer
Denosumab
Enzalutamide
Abiraterone
Prednisone
18 Years - University of Hawaii
Duration of Enzalutamide and ADT With Metastasis Directed Therapy in Oligometastatic Cancer of the Prostate (DIRECT)NCT05404139
Metastatic Pros...
Enzalutamide
Standard of Car...
18 Years - 100 YearsUniversity Health Network, Toronto
Comparative Study of Alternative Antiandrogen (AA) Therapy and Early Initiating of Enzalutamide for Castration-resistant Prostate Cancer (CRPC) After Combined Androgen Blockade (CAB) Therapy.NCT02346578
Castration-resi...
Enzalutamide
Flutamide
20 Years - Osaka City University
A Study for Subjects With Prostate Cancer Who Previously Participated in an Enzalutamide Clinical StudyNCT02960022
Prostate Cancer
enzalutamide
abiraterone ace...
prednisone
18 Years - Astellas Pharma Inc
An Observational Study, Called DEAR, to Learn More About Treatment With Darolutamide, Enzalutamide and Apalutamide in Men With Non-metastatic Castration-resistant Prostate Cancer in Real World SettingsNCT05362149
Non-metastatic ...
Darolutamide (N...
Enzalutamide
Apalutamide
18 Years - Bayer
A Study to Learn About Novel Hormonal Therapies in People With Metastatic Castration-Sensitive Prostate Cancer (mCSPC)NCT06072196
Prostatic Neopl...
Novel hormonal ...
65 Years - Pfizer
Enhanced Systemic Combined With Local Treatment for Primary and Metastatic Lesions in Oligo-metastatic Prostate CancerNCT05212857
Prostate Cancer
Leuprolide acet...
Goserelin aceta...
Triptorelin ace...
Degarelix aceta...
Abiraterone ace...
Apalutamide
Enzalutamide
Local treatment...
Radiotherapy fo...
Radiotherapy fo...
18 Years - 80 YearsFudan University
Study of Pembrolizumab (MK-3475) Plus Enzalutamide Versus Placebo Plus Enzalutamide in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-3475-641/KEYNOTE-641)NCT03834493
Prostatic Neopl...
Pembrolizumab
Enzalutamide
Placebo
18 Years - Merck Sharp & Dohme LLC
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