Spots Global Cancer Trial Database for S9811 Hydroxyurea in Treating Patients With Unresectable Benign Meningioma
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Trial Identification
Brief Title: S9811 Hydroxyurea in Treating Patients With Unresectable Benign Meningioma
Official Title: Phase II Study of Hydroxyurea for Unresectable Meningioma
Study ID: NCT00003590
Conditions
Interventions
Study Description
Brief Summary: RATIONALE: Drugs used in chemotherapy such as hydroxyurea use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: This phase II trial is studying how well hydroxyurea works in treating patients with unresectable benign meningioma.
Detailed Description: OBJECTIVES: * Determine the partial and complete response rates in patients with unresectable benign meningioma treated with hydroxyurea. * Assess the quantitative and qualitative toxic effects of this drug in this patient population. OUTLINE: Patients receive oral hydroxyurea twice daily for 2 years in the absence of disease progression or unacceptable toxicity. Patients are followed at 3 months, 6 months, and then every 6 months for 3 years. PROJECTED ACCRUAL: A total of 38 patients will be accrued for this study within 13 months.
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Fairbanks Cancer Treatment Center at Fairbanks Memorial Hospital, Fairbanks, Alaska, United States
St. Joseph's Hospital and Medical Center, Phoenix, Arizona, United States
CCOP - Western Regional, Arizona, Phoenix, Arizona, United States
Arkansas Cancer Research Center at University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States
City of Hope Comprehensive Cancer Center, Duarte, California, United States
CCOP - Bay Area Tumor Institute, Oakland, California, United States
University of California Davis Cancer Center, Sacramento, California, United States
University of Colorado Cancer Center at University of Colorado Health Sciences Center, Aurora, Colorado, United States
St. Anthony Central Hospital, Denver, Colorado, United States
Denver Health Medical Center, Denver, Colorado, United States
Veterans Affairs Medical Center - Denver, Denver, Colorado, United States
Montrose Memorial Hospital Cancer Center, Montrose, Colorado, United States
St. Anthony North Hospital, Westminster, Colorado, United States
Exempla Lutheran Medical Center, Wheat Ridge, Colorado, United States
M.D. Anderson Cancer Center - Orlando, Orlando, Florida, United States
North Idaho Cancer Center, Coeur d'Alene, Idaho, United States
Rush-Copley Cancer Care Center, Aurora, Illinois, United States
St. Joseph Medical Center, Bloomington, Illinois, United States
Graham Hospital, Canton, Illinois, United States
Memorial Hospital, Carthage, Illinois, United States
University of Illinois Medical Center, Chicago, Illinois, United States
Veterans Affairs Medical Center - Chicago Westside Hospital, Chicago, Illinois, United States
Eureka Hospital, Eureka, Illinois, United States
Galesburg Clinic, Galesburg, Illinois, United States
Galesburg Cottage Hospital, Galesburg, Illinois, United States
InterCommunity Cancer Center of Western Illinois, Galesburg, Illinois, United States
Mason District Hospital, Havana, Illinois, United States
Hopedale Medical Complex, Hopedale, Illinois, United States
Joliet Oncology Hematology Associates, Limited - West, Joliet, Illinois, United States
Kewanee Hospital, Kewanee, Illinois, United States
McDonough District Hospital, Macomb, Illinois, United States
Edward Hospital Cancer Center, Naperville, Illinois, United States
BroMenn Regional Medical Center, Normal, Illinois, United States
Community Cancer Center, Normal, Illinois, United States
Community Hospital of Ottawa, Ottawa, Illinois, United States
Oncology Hematology Associates of Central Illinois - Ottawa, Ottawa, Illinois, United States
Cancer Treatment Center at Pekin Hospital, Pekin, Illinois, United States
Proctor Hospital, Peoria, Illinois, United States
CCOP - Illinois Oncology Research Association, Peoria, Illinois, United States
Oncology/Hematology Associates of Central Illinois, P.C., Peoria, Illinois, United States
Methodist Medical Center of Illinois, Peoria, Illinois, United States
OSF St. Francis Medical Center, Peoria, Illinois, United States
Illinois Valley Community Hospital, Peru, Illinois, United States
Perry Memorial Hospital, Princeton, Illinois, United States
St. Margaret's Hospital, Spring Valley, Illinois, United States
Valley Cancer Center, Spring Valley, Illinois, United States
Carle Cancer Center at Carle Foundation Hospital, Urbana, Illinois, United States
Carle Clinic Association, Urbana, Illinois, United States
Saint Anthony Memorial Health Centers, Michigan City, Indiana, United States
Siouxland Hematology-Oncology Associates, Sioux City, Iowa, United States
Mercy Medical Center - Sioux City, Sioux City, Iowa, United States
St. Luke's Regional Medical Center, Sioux City, Iowa, United States
Cancer Center of Kansas - Chanute, Chanute, Kansas, United States
Cancer Center of Kansas, P.A. - El Dorado, El Dorado, Kansas, United States
Cancer Center of Kansas - Kingman, Kingman, Kansas, United States
Southwest Medical Center, Liberal, Kansas, United States
Cancer Center of Kansas - Newton, Newton, Kansas, United States
Cancer Center of Kansas - Ottawa, Ottawa, Kansas, United States
Cancer Center of Kansas, P.A. - Parsons, Parsons, Kansas, United States
Pratt Cancer Center of Kansas, Pratt, Kansas, United States
Cancer Center of Kansas - Salina, Salina, Kansas, United States
Salina Regional Health Center, Salina, Kansas, United States
Cancer Center of Kansas - Wellington, Wellington, Kansas, United States
Associates in Womens Health, Wichita, Kansas, United States
Cancer Center of Kansas, P.A. - Wichita, Wichita, Kansas, United States
CCOP - Wichita, Wichita, Kansas, United States
Via Christi Cancer Center at Via Christi Regional Medical Center, Wichita, Kansas, United States
Cancer Center of Kansas - Winfield, Winfield, Kansas, United States
Mary Bird Perkins Cancer Center - Baton Rouge, Baton Rouge, Louisiana, United States
Baton Rouge General Regional Cancer Center, Baton Rouge, Louisiana, United States
Cancer Center at Medical Center of Louisiana - New Orleans, New Orleans, Louisiana, United States
DeCesaris Cancer Institute at Anne Arundel Medical Center, Annapolis, Maryland, United States
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States
Josephine Ford Cancer Center at Henry Ford Health System, Detroit, Michigan, United States
Fairview Ridges Hospital, Burnsville, Minnesota, United States
Mercy Hospital, Coon Rapids, Minnesota, United States
Fairview Southdale Hospital, Edina, Minnesota, United States
Mercy and Unity Cancer Center at Mercy and Unity Hospitals, Fridley, Minnesota, United States
Virginia Piper Cancer Institute at Abbott-Northwestern Hospital, Minneapolis, Minnesota, United States
Hubert H. Humphrey Cancer Center at North Memorial Medical Center, Robbinsdale, Minnesota, United States
CCOP - Metro-Minnesota, Saint Louis Park, Minnesota, United States
United Hospital, Saint Paul, Minnesota, United States
Park Nicollet Clinic, St. Louis Park, Minnesota, United States
Ridgeview Medical Center, Waconia, Minnesota, United States
University of Mississippi Medical Center, Jackson, Mississippi, United States
Veterans Affairs Medical Center - Kansas City, Kansas City, Missouri, United States
CCOP - Kansas City, Kansas City, Missouri, United States
CCOP - Montana Cancer Consortium, Billings, Montana, United States
Great Falls Clinic, Great Falls, Montana, United States
Adena Regional Medical Center, Chillicothe, Ohio, United States
Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio, United States
CCOP - Columbus, Columbus, Ohio, United States
Riverside Methodist Hospital Cancer Care, Columbus, Ohio, United States
Mount Carmel West Hospital, Columbus, Ohio, United States
Doctors Hospital at Ohio Health, Columbus, Ohio, United States
Grady Memorial Hospital, Delaware, Ohio, United States
Community Oncology Group - Independence, Independence, Ohio, United States
Fairfield Medical Center, Lancaster, Ohio, United States
Strecker Cancer Center at Marietta Memorial Hospital, Marietta, Ohio, United States
Licking Memorial Cancer Care Program at Licking Memorial Hospital, Newark, Ohio, United States
Mercy Medical Center Oncology Unit, Springfield, Ohio, United States
Community Hospital of Springfield and Clark County, Springfield, Ohio, United States
Rose Ramer Cancer Clinic at Anderson Area Medical Center, Anderson, South Carolina, United States
CCOP - Greenville, Greenville, South Carolina, United States
Sioux Valley Hospital and University of South Dakota Medical Center, Sioux Falls, South Dakota, United States
Avera McKennan Hospital and University Health Center, Sioux Falls, South Dakota, United States
Medical X-Ray Center, Sioux Falls, South Dakota, United States
Brooke Army Medical Center, Fort Sam Houston, Texas, United States
Wilford Hall Medical Center, Lackland Air Force Base, Texas, United States
Center for Cancer Prevention and Care at Scott and White Clinic, Temple, Texas, United States
American Fork Hospital, American Fork, Utah, United States
Logan Regional Hospital, Logan, Utah, United States
Cottonwood Hospital Medical Center, Murray, Utah, United States
McKay-Dee Hospital Center, Ogden, Utah, United States
Utah Valley Regional Medical Center - Provo, Provo, Utah, United States
Dixie Regional Medical Center, Saint George, Utah, United States
Huntsman Cancer Institute at University of Utah, Salt Lake City, Utah, United States
LDS Hospital, Salt Lake City, Utah, United States
Grays Harbor Community Hospital, Aberdeen, Washington, United States
Auburn Regional Center for Cancer Care at Auburn Regional Medical Center, Auburn, Washington, United States
St. Francis Hospital, Federal Way, Washington, United States
Cascade Cancer Center at Evergreen Hospital Medical Center, Kirkland, Washington, United States
St. Clare Hospital, Lakewood, Washington, United States
Capital Medical Center, Olympia, Washington, United States
Providence St. Peter Hospital Regional Cancer Center, Olympia, Washington, United States
Olympic Medical Center, Port Angeles, Washington, United States
Good Samaritan Cancer Center, Puyallup, Washington, United States
Valley Medical Center, Renton, Washington, United States
CCOP - Virginia Mason Research Center, Seattle, Washington, United States
CCOP - Northwest, Tacoma, Washington, United States
St. Joseph Medical Center at Franciscan Health System, Tacoma, Washington, United States
Allenmore Hospital, Tacoma, Washington, United States
Camden-Clark Memorial Hospital, Parkersburg, West Virginia, United States
Contact Details
Name: Lode J. Swinnen, MD
Affiliation: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Role: STUDY_CHAIR
Name: Geoffrey R. Barger, MD
Affiliation: Barbara Ann Karmanos Cancer Institute
Role: STUDY_CHAIR
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