Spots Global Cancer Trial Database for recurrent adult brain tumor
Every month we try and update this database with for recurrent adult brain tumor cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Pazopanib in Treating Patients With Recurrent Glioblastoma | NCT00459381 | Adult Giant Cel... Adult Glioblast... Adult Gliosarco... Recurrent Adult... | pazopanib hydro... laboratory biom... | 18 Years - | National Cancer Institute (NCI) | |
| Dovitinib in Treating Patients With Recurrent or Progressive Glioblastoma | NCT01753713 | Adult Giant Cel... Adult Glioblast... Adult Gliosarco... Recurrent Adult... | dovitinib laboratory biom... | 18 Years - | Case Comprehensive Cancer Center | |
| Changes in Semen or Sperm Caused by Temozolomide in Patients With Newly Diagnosed, Progressive, or Recurrent Primary Malignant Brain Tumors | NCT00499798 | Brain and Centr... Chemotherapeuti... Infertility | 18 Years - 60 Years | Wake Forest University Health Sciences | ||
| Irinotecan Plus Carmustine in Treating Patients With Recurrent Primary Malignant Glioma | NCT00002988 | Brain and Centr... | carmustine irinotecan hydr... | 18 Years - | Duke University | |
| Suramin in Treating Patients With Recurrent Primary Brain Tumors | NCT00002639 | Brain and Centr... | chemotherapy suramin | 15 Years - | National Cancer Institute (NCI) | |
| Temozolomide in Treating Patients With Primary Brain Tumors or Metastatic Brain Tumors | NCT00547131 | Brain and Centr... Metastatic Canc... | temozolomide laboratory biom... liquid chromato... mass spectromet... pharmacological... conventional su... stereotactic ra... | 18 Years - 120 Years | City of Hope Medical Center | |
| Radiation Therapy With and Without Combination Chemotherapy in Patients With Resected Anaplastic Oligodendroglioma | NCT00002840 | Brain and Centr... | lomustine procarbazine hy... vincristine sul... radiation thera... | 16 Years - 69 Years | European Organisation for Research and Treatment of Cancer - EORTC | |
| Chemotherapy in Treating Patients With Recurrent Malignant Glioma | NCT00002986 | Brain and Centr... | carmustine topotecan hydro... | 18 Years - | Duke University | |
| Irinotecan Plus Temozolomide in Treating Patients With Recurrent Primary Malignant Glioma | NCT00005951 | Brain and Centr... | irinotecan hydr... temozolomide | 18 Years - | Duke University | |
| Vaccine Therapy With Bevacizumab Versus Bevacizumab Alone in Treating Patients With Recurrent Glioblastoma Multiforme That Can Be Removed by Surgery | NCT01814813 | Recurrent Gliob... Recurrent Adult... Gliosarcoma | HSPPC-96 bevacizumab | 18 Years - | Alliance for Clinical Trials in Oncology | |
| Carboplatin in Patients With Progressive Gliomas | NCT00002749 | Brain and Centr... | carboplatin | - | Duke University | |
| Erlotinib Hydrochloride and Isotretinoin in Treating Patients With Recurrent Malignant Glioma | NCT01103375 | Adult Anaplasti... Adult Anaplasti... Adult Diffuse A... Adult Giant Cel... Adult Glioblast... Adult Gliosarco... Adult Mixed Gli... Adult Oligodend... Recurrent Adult... | erlotinib hydro... isotretinoin laboratory biom... protein express... | 18 Years - | Wake Forest University Health Sciences | |
| Calcitriol Plus Carboplatin in Treating Patients With Advanced Solid Tumors | NCT00008086 | Brain and Centr... Unspecified Adu... | calcitriol carboplatin | 18 Years - | University of Pittsburgh | |
| CCI-779 in Treating Patients With Advanced Solid Tumors | NCT00003712 | Brain and Centr... Metastatic Canc... Unspecified Adu... | temsirolimus | 18 Years - | The University of Texas Health Science Center at San Antonio | |
| Temozolomide in Treating Patients With Recurrent High-Grade Glioma | NCT00619112 | Recurrent Centr... | temozolomide | 18 Years - | University of California, San Francisco | |
| Bevacizumab and Lomustine for Recurrent GBM | NCT01290939 | Glioblastoma Mu... Cognition Disor... Disability Eval... | bevacizumab lomustine DNA methylation... laboratory biom... cognitive asses... quality-of-life... | 18 Years - | European Organisation for Research and Treatment of Cancer - EORTC | |
| Leflunomide in Treating Patients With Anaplastic Astrocytoma in First Relapse | NCT00003775 | Brain and Centr... | leflunomide | 18 Years - | Pfizer | |
| Temozolomide Plus Carboplatin in Treating Patients With Recurrent Glioblastoma Multiforme | NCT00021307 | Brain and Centr... | carboplatin temozolomide | 18 Years - | Fox Chase Cancer Center | |
| Ramucirumab or Anti-PDGFR Alpha Monoclonal Antibody IMC-3G3 in Treating Patients With Recurrent Glioblastoma Multiforme | NCT00895180 | Adult Glioblast... | olaratumab ramucirumab | 18 Years - | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Photodynamic Therapy With Porfimer Sodium in Treating Patients With Refractory Brain Tumors | NCT00002647 | Brain and Centr... Metastatic Canc... | verteporfin conventional su... | 3 Years - 70 Years | National Cancer Institute (NCI) | |
| Immunotoxin Therapy Before and After Surgery in Treating Patients With Recurrent Malignant Glioma | NCT00036972 | Brain and Centr... | cintredekin bes... adjuvant therap... conventional su... neoadjuvant the... | 18 Years - | National Cancer Institute (NCI) | |
| AEE788 and Everolimus in Treating Patients With Recurrent or Relapsed Glioblastoma Multiforme | NCT00107237 | Brain and Centr... | AEE788 everolimus | 18 Years - | Novartis | |
| VEGF Trap in Treating Patients With Recurrent Malignant Gliomas That Did Not Respond to Temozolomide | NCT00369590 | Adult Anaplasti... Adult Anaplasti... Adult Giant Cel... Adult Gliosarco... Recurrent Adult... | ziv-aflibercept pharmacological... laboratory biom... | 18 Years - | National Cancer Institute (NCI) | |
| Bevacizumab and Lomustine for Recurrent GBM | NCT01290939 | Glioblastoma Mu... Cognition Disor... Disability Eval... | bevacizumab lomustine DNA methylation... laboratory biom... cognitive asses... quality-of-life... | 18 Years - | European Organisation for Research and Treatment of Cancer - EORTC | |
| Bortezomib and Temozolomide in Treating Patients With Advanced Refractory Solid Tumors or Melanoma | NCT00512798 | Brain and Centr... Melanoma Solid Tumor | PS-341 (VELCADE... temozolomide immunoenzyme te... PS-341 (VELCADE... Temozolomide | 18 Years - | Vanderbilt-Ingram Cancer Center | |
| Thiotepa Followed by Peripheral Stem Cell or Bone Marrow Transplant in Treating Patients With Malignant Glioma | NCT00008008 | Brain and Centr... | filgrastim sargramostim cyclophosphamid... thiotepa autologous bone... bone marrow abl... peripheral bloo... | - | National Cancer Institute (NCI) | |
| Temozolomide in Treating Patients With Recurrent or Progressive Malignant Glioma | NCT00004204 | Brain and Centr... | temozolomide | 18 Years - | National Cancer Institute (NCI) | |
| Sirolimus in Treating Patients With Glioblastoma Multiforme | NCT00047073 | Brain and Centr... | Rapamycin Surgery Supportive Care | 18 Years - 120 Years | Jonsson Comprehensive Cancer Center | |
| Bevacizumab in Recurrent Grade II and III Glioma | NCT01164189 | Central Nervous... | Bevacizumab Temozolomide | 18 Years - | European Organisation for Research and Treatment of Cancer - EORTC | |
| Vaccine Therapy in Treating Patients With Malignant Glioma | NCT00612001 | Brain and Centr... | glioma-associat... | 18 Years - | Jonsson Comprehensive Cancer Center | |
| Magnetic Resonance Spectroscopy Imaging in Predicting Response to Vorinostat and Temozolomide in Patients With Recurrent or Progressive Glioblastoma | NCT01342757 | Adult Glioblast... Depression Recurrent Adult... | vorinostat temozolomide magnetic resona... survey administ... | 18 Years - | National Cancer Institute (NCI) | |
| Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation or Bone Marrow Transplantation in Treating Patients With Brain Cancer | NCT00025558 | Brain and Centr... | filgrastim carboplatin temozolomide thiotepa autologous bone... peripheral bloo... | 1 Year - 49 Years | NYU Langone Health | |
| Tumor Tissue Analysis in Patients Receiving Imatinib Mesylate for Malignant Glioma | NCT00401024 | Brain and Centr... | imatinib mesyla... pharmacological... conventional su... | 18 Years - 120 Years | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Vatalanib in Treating Patients With Recurrent or Progressive Meningioma | NCT00348790 | Brain and Centr... Sarcoma | vatalanib | 18 Years - | Northwestern University | |
| Vaccine Therapy and Sargramostim in Treating Patients With Sarcoma or Brain Tumor | NCT00069940 | Brain and Centr... Gastrointestina... Sarcoma | sargramostim telomerase: 540... | 2 Years - | Dana-Farber Cancer Institute | |
| GP96 Heat Shock Protein-Peptide Complex Vaccine in Treating Patients With Recurrent or Progressive Glioma | NCT00293423 | Brain and Centr... | HSPPC-96 Standard Surgic... | 18 Years - | University of California, San Francisco | |
| Gimatecan in Treating Patients With Recurrent or Progressive Primary Malignant Glioma | NCT00087061 | Brain and Centr... | gimatecan | 18 Years - | National Cancer Institute (NCI) | |
| Procarbazine in Treating Patients With Recurrent Brain Tumor | NCT00004004 | Brain and Centr... | procarbazine hy... | 18 Years - | National Cancer Institute (NCI) | |
| A Study Assessing Pamiparib With Radiation and/or Temozolomide (TMZ) in Participants With Newly Diagnosed or Recurrent Glioblastoma | NCT03150862 | Brain and Centr... | Pamiparib TMZ Radiation | 18 Years - | BeiGene | |
| Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Brain Tumors | NCT00003461 | Brain and Centr... Metastatic Canc... Neuroblastoma | surgical proced... astatine At 211... | 18 Years - | Duke University | |
| ATN-161 and Carboplatin in Treating Patients With Recurrent Malignant Glioma | NCT00352313 | Brain and Centr... | ATN-161 carboplatin | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Olaparib and Temozolomide in Treating Patients With Relapsed Glioblastoma | NCT01390571 | Brain and Centr... | olaparib temozolomide gene expression... protein express... laboratory biom... pharmacological... diffusion-weigh... dynamic contras... therapeutic con... | 18 Years - | Cancer Research UK | |
| Fenretinide in Treating Patients With Recurrent Malignant Glioma | NCT00006080 | Brain and Centr... | fenretinide | 18 Years - 120 Years | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Melphalan With BBBD in Treating Patients With Brain Malignancies | NCT00253721 | Brain and Centr... Lymphoma Metastatic Canc... | Melphalan | 18 Years - 120 Years | OHSU Knight Cancer Institute | |
| Imatinib Mesylate in Treating Patients With Recurrent Malignant Glioma or Meningioma | NCT00010049 | Brain and Centr... | imatinib mesyla... | 18 Years - 120 Years | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Vaccine Therapy With Bevacizumab Versus Bevacizumab Alone in Treating Patients With Recurrent Glioblastoma Multiforme That Can Be Removed by Surgery | NCT01814813 | Recurrent Gliob... Recurrent Adult... Gliosarcoma | HSPPC-96 bevacizumab | 18 Years - | Alliance for Clinical Trials in Oncology | |
| O(6)-Benzylguanine and Temozolomide in Treating Patients With Glioblastoma Multiforme That Did Not Respond to Previous Temozolomide and Radiation Therapy | NCT00436436 | Brain and Centr... | O6-benzylguanin... temozolomide | 18 Years - 120 Years | National Institutes of Health Clinical Center (CC) | |
| Bevacizumab and Lomustine for Recurrent GBM | NCT01290939 | Glioblastoma Mu... Cognition Disor... Disability Eval... | bevacizumab lomustine DNA methylation... laboratory biom... cognitive asses... quality-of-life... | 18 Years - | European Organisation for Research and Treatment of Cancer - EORTC | |
| Karenitecin in Treating Patients With Recurrent Malignant Glioma | NCT00014521 | Brain and Centr... | karenitecin | 18 Years - | National Cancer Institute (NCI) | |
| Acridine Carboxamide in Treating Patients With Recurrent Glioblastoma Multiforme | NCT00004937 | Brain and Centr... | acridine carbox... | 18 Years - | European Organisation for Research and Treatment of Cancer - EORTC | |
| EMD 121974 in Treating Patients With Progressive or Recurrent Glioma | NCT00006093 | Brain and Centr... | cilengitide | 18 Years - | National Cancer Institute (NCI) | |
| Chemotherapy in Treating Patients With Progressive or Recurrent Brain Tumors | NCT00012038 | Brain and Centr... | irofulven | 18 Years - | National Cancer Institute (NCI) | |
| Acridine Carboxamide in Treating Patients With Recurrent Glioblastoma Multiforme | NCT00004937 | Brain and Centr... | acridine carbox... | 18 Years - | European Organisation for Research and Treatment of Cancer - EORTC | |
| IL-4(38-37)-PE38KDEL Immunotoxin in Treating Patients With Recurrent Malignant Astrocytoma | NCT00003842 | Brain and Centr... | interleukin-4 P... isolated perfus... surgical proced... | 18 Years - | National Cancer Institute (NCI) | |
| Temozolomide Plus Thalidomide in Treating Patients With Recurrent or Progressive Brain Tumor | NCT00006358 | Brain and Centr... | temozolomide thalidomide | 18 Years - 120 Years | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Carmustine in Treating Patients With Recurrent Malignant Glioma | NCT00004028 | Brain and Centr... | carmustine conventional su... | 18 Years - | National Cancer Institute (NCI) | |
| Bevacizumab With or Without Radiation Therapy in Treating Patients With Recurrent Glioblastoma | NCT01730950 | Adult Giant Cel... Adult Glioblast... Adult Gliosarco... Recurrent Adult... | bevacizumab radiation thera... | 18 Years - | Radiation Therapy Oncology Group | |
| Aminolevulinic Acid in Visualizing a Tumor During Surgery in Patients With Glioblastoma Multiforme | NCT01575275 | Adult Giant Cel... Adult Glioblast... Adult Gliosarco... Recurrent Adult... | aminolevulinic ... therapeutic con... | 18 Years - | Case Comprehensive Cancer Center | |
| Tumor DNA and MRI/CT Scan Findings in Patients With Grade III or Grade IV Malignant Glioma | NCT00897611 | High Grade Glio... | DNA methylation... polymerase chai... computed tomogr... magnetic resona... | 18 Years - | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Monoclonal Antibody Therapy in Treating Patients With Recurrent Gliomas | NCT00002753 | Brain and Centr... | iodine I 131 mo... | 3 Years - | Duke University | |
| Zoledronate in Preventing Osteoporosis in Patients With Primary Malignant Glioma | NCT00301873 | Brain Tumors Osteoporosis Central Nervous... | IV Zometa | 18 Years - | Duke University | |
| Biological Therapy in Treating Patients With Primary or Advanced Glioma | NCT00003067 | Brain and Centr... | aldesleukin lymphokine-acti... | 18 Years - | National Cancer Institute (NCI) | |
| Biological Therapy in Treating Patients With Primary or Advanced Glioma | NCT00003067 | Brain and Centr... | aldesleukin lymphokine-acti... | 18 Years - | National Cancer Institute (NCI) | |
| Tandutinib in Treating Patients With Recurrent or Progressive Glioblastoma | NCT00379080 | Adult Brain Tum... Adult Giant Cel... Adult Glioblast... Adult Gliosarco... Recurrent Adult... | conventional su... tandutinib pharmacological... Tissue samples | 18 Years - | National Cancer Institute (NCI) | |
| 18F-FDOPA PET/CT or PET/MRI in Measuring Tumors in Patients With Newly-Diagnosed or Recurrent Gliomas | NCT02175745 | Adult Anaplasti... Adult Anaplasti... Adult Brain Ste... Adult Diffuse A... Adult Giant Cel... Adult Glioblast... Adult Gliosarco... Adult Mixed Gli... Adult Oligodend... Adult Pilocytic... Adult Pineal Gl... Adult Subependy... Childhood High-... Childhood High-... Childhood Low-g... Childhood Low-g... Recurrent Adult... Recurrent Child... Recurrent Child... Recurrent Child... Recurrent Child... Recurrent Child... Recurrent Child... Recurrent Child... Recurrent Child... Recurrent Child... Recurrent Child... Recurrent Child... Recurrent Child... Recurrent Child... Recurrent Child... Recurrent Child... Recurrent Child... Recurrent Child... Recurrent Child... Recurrent Child... Recurrent Child... Untreated Child... Untreated Child... Untreated Child... Untreated Child... Untreated Child... Untreated Child... Untreated Child... Untreated Child... Untreated Child... Untreated Child... Untreated Child... Untreated Child... Untreated Child... Untreated Child... Untreated Child... Untreated Child... Untreated Child... Untreated Child... Untreated Child... Untreated Child... | 18F-fluoro-dihy... Positron emissi... Computed tomogr... Magnetic resona... | 16 Years - | Stanford University | |
| Tamoxifen, Carboplatin, and Topotecan in Treating Patients With CNS Metastases or Recurrent Brain or Spinal Cord Tumors | NCT00541138 | Brain and Centr... Metastatic Canc... Unspecified Adu... | carboplatin tamoxifen citra... topotecan hydro... pharmacological... | 18 Years - | City of Hope Medical Center | |
| Combination Chemotherapy and Tamoxifen in Treating Patients With Solid Tumors | NCT00002608 | Adrenocortical ... Brain and Centr... Head and Neck C... Liver Cancer Malignant Mesot... Pheochromocytom... Sarcoma | cisplatin doxorubicin hyd... tamoxifen citra... conventional su... radiation thera... | - 65 Years | National Cancer Institute (NCI) | |
| Aminolevulinic Acid in Visualizing a Tumor During Surgery in Patients With Glioblastoma Multiforme | NCT01575275 | Adult Giant Cel... Adult Glioblast... Adult Gliosarco... Recurrent Adult... | aminolevulinic ... therapeutic con... | 18 Years - | Case Comprehensive Cancer Center | |
| Temozolomide in Treating Patients With Anaplastic Oligodendroglioma | NCT00003465 | Brain and Centr... | temozolomide | 18 Years - | Duke University | |
| Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation or Bone Marrow Transplantation in Treating Patients With Brain Cancer | NCT00025558 | Brain and Centr... | filgrastim carboplatin temozolomide thiotepa autologous bone... peripheral bloo... | 1 Year - 49 Years | NYU Langone Health | |
| FR901228 in Treating Patients With Recurrent High-Grade Gliomas | NCT00085540 | Adult Anaplasti... Adult Anaplasti... Adult Giant Cel... Adult Gliosarco... Recurrent Adult... | depsipeptide | 18 Years - | National Cancer Institute (NCI) | |
| Bortezomib and Temozolomide in Treating Patients With Advanced Refractory Solid Tumors or Melanoma | NCT00512798 | Brain and Centr... Melanoma Solid Tumor | PS-341 (VELCADE... temozolomide immunoenzyme te... PS-341 (VELCADE... Temozolomide | 18 Years - | Vanderbilt-Ingram Cancer Center | |
| Lonafarnib and Temozolomide in Treating Patients With Recurrent Primary Supratentorial Gliomas | NCT00083096 | Brain and Centr... | lonafarnib temozolomide | 18 Years - | European Organisation for Research and Treatment of Cancer - EORTC | |
| Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Brain Tumors | NCT00003461 | Brain and Centr... Metastatic Canc... Neuroblastoma | surgical proced... astatine At 211... | 18 Years - | Duke University | |
| Hydroxyurea in Treating Patients With Recurrent and/or Unresectable Meningioma | NCT00006119 | Brain and Centr... | hydroxyurea | 16 Years - 120 Years | UNICANCER | |
| Bortezomib in Treating Patients With Recurrent Glioma | NCT00006773 | Adult Anaplasti... Adult Anaplasti... Adult Giant Cel... Adult Glioblast... Adult Gliosarco... Recurrent Adult... | bortezomib | 18 Years - | National Cancer Institute (NCI) | |
| Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Glucocorticoids, in Combination With Interleukin-2 | NCT01082926 | Anaplastic Astr... Anaplastic Epen... Anaplastic Meni... Anaplastic Olig... Brain Stem Glio... Ependymoblastom... Giant Cell Glio... Glioblastoma Gliosarcoma Grade III Menin... Meningeal Heman... Mixed Glioma Pineal Gland As... Brain Tumor | therapeutic all... aldesleukin laboratory biom... positron emissi... | 18 Years - 70 Years | City of Hope Medical Center | |
| ZD 1839 in Treating Patients With Glioblastoma Multiforme in First Relapse | NCT00016991 | Brain and Centr... | gefitinib | 18 Years - | Duke University | |
| Poly-ICLC in Treating Patients With Recurrent or Progressive Anaplastic Glioma | NCT00058123 | Brain and Centr... | poly ICLC | 18 Years - 120 Years | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| O(6)-Benzylguanine and Temozolomide in Treating Patients With Glioblastoma Multiforme That Did Not Respond to Previous Temozolomide and Radiation Therapy | NCT00436436 | Brain and Centr... | O6-benzylguanin... temozolomide | 18 Years - 120 Years | National Institutes of Health Clinical Center (CC) |
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