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Brief Title: Safety and Efficacy Study of Enzalutamide in Patients With Advanced, Androgen Receptor-Positive, Triple Negative Breast Cancer
Official Title: A PHASE 2, SINGLE-ARM, OPEN-LABEL, MULTICENTER STUDY OF THE CLINICAL ACTIVITY AND SAFETY OF ENZALUTAMIDE IN PATIENTS WITH ADVANCED, ANDROGEN RECEPTOR-POSITIVE, TRIPLE-NEGATIVE BREAST CANCER
Study ID: NCT01889238
Brief Summary: The purpose of this study is to determine if enzalutamide is safe and effective in the treatment of patients with advanced breast cancer that express the androgen receptor but do not express the estrogen or progesterone receptor and are not Her2 amplified.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Rocky Mountain Cancer Centers, Colorado Springs, Colorado, United States
Rocky Mountain Cancer Centers, Lakewood, Colorado, United States
Rocky Mountain Cancer Centers, Lone Tree, Colorado, United States
Florida Cancer Specialists, Altamonte Springs, Florida, United States
Florida Cancer Specialists, Bonita Springs, Florida, United States
Florida Cancer Specialists, Bradenton, Florida, United States
Florida Cancer Specialists, Brandon, Florida, United States
Florida Cancer Specialists, Cape Coral, Florida, United States
Florida Cancer Specialists, Clearwater, Florida, United States
Florida Cancer Specialists, Fort Myers, Florida, United States
Florida Cancer Specialists, Fort Myers, Florida, United States
Florida Cancer Specialists, Fort Myers, Florida, United States
Florida Cancer Specialists, Gainesville, Florida, United States
Florida Cancer Specialists, Hudson, Florida, United States
Florida Cancer Specialists, Largo, Florida, United States
Florida Cancer Specialists, Naples, Florida, United States
Florida Cancer Specialists, New Port Richey, Florida, United States
Florida Cancer Specialists, Orange City, Florida, United States
Florida Cancer Specialists, Orlando, Florida, United States
Florida Cancer Specialists, Port Charlotte, Florida, United States
Florida Cancer Specialists, Saint Petersburg, Florida, United States
Florida Cancer Specialists, Sarasota, Florida, United States
Florida Cancer Specialists, Sarasota, Florida, United States
Florida Cancer Specialists, Spring Hill, Florida, United States
Florida Cancer Specialists, Tampa, Florida, United States
Florida Cancer Specialists, Tavares, Florida, United States
Florida Cancer Specialists, Venice, Florida, United States
Florida Cancer Specialists, Venice, Florida, United States
Northwestern Medical Faculty Foundation(NMFF)/ Women's Cancer Center Shared Laboratories, Chicago, Illinois, United States
Northwestern Medical Faculty Foundation, Chicago, Illinois, United States
Northwestern Memorial Hospital, Chicago, Illinois, United States
The University of Chicago Medical Center, Investigational Drug Service Department of Pharmacy, Chicago, Illinois, United States
The University of Chicago, Chicago, Illinois, United States
University of Chicago Comprehensive Cancer Center at Silver Cross Hospital, New Lenox, Illinois, United States
Indiana University Health Hospital, Indianapolis, Indiana, United States
Indiana University Health Melvin and Bren Simon Cancer Center, Indianapolis, Indiana, United States
Investigational Drug Services, Indianapolis, Indiana, United States
Sidney and Lois Eskenazi Hospital, Indianapolis, Indiana, United States
Springmill Medical Clinic, Indianapolis, Indiana, United States
Oncology Hematology Care, Inc., Crestview Hills, Kentucky, United States
Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States
Dana-Farber Cancer Institute, Boston, Massachusetts, United States
The West Clinic, PC, Corinth, Mississippi, United States
The West Clinic, PC, Southaven, Mississippi, United States
Barnes-Jewish Hospital, Saint Louis, Missouri, United States
Washington University Infusion Center Pharmacy, Saint Louis, Missouri, United States
Washington University School of Medicine, Saint Louis, Missouri, United States
Siteman Cancer Center-South County, Saint Louis, Missouri, United States
Siteman Cancer Center-West County, Saint Louis, Missouri, United States
Siteman Cancer Center, Saint Peters, Missouri, United States
Hematology Oncology Associates of Northern NJ, Morristown, New Jersey, United States
Memorial Sloan Kettering - I Chemotherapy Practice/Investigational Drug Service, New York, New York, United States
Memorial Sloan-Kettering Cancer Center, New York, New York, United States
Cone Health Cancer Center, Greensboro, North Carolina, United States
Wesley Long Community Hospital, Greensboro, North Carolina, United States
Oncology Hematology Care, Inc., Cincinnati, Ohio, United States
Oncology Hematology Care, Inc., Cincinnati, Ohio, United States
Oncology Hematology Care, Inc., Cincinnati, Ohio, United States
Oncology Hematology Care, Inc., Cincinnati, Ohio, United States
Oncology Hematology Care, Inc., Cincinnati, Ohio, United States
Oncology Hematology Care, Inc., Fairfield, Ohio, United States
Greenville Health System, Greenville, South Carolina, United States
Greenville Health System, Seneca, South Carolina, United States
Greenville Health System, Spartanburg, South Carolina, United States
Tennessee Oncology, PLLC, Dickson, Tennessee, United States
Tennessee Oncology, PLLC, Franklin, Tennessee, United States
Tennessee Oncology, PLLC, Gallatin, Tennessee, United States
Tennessee Oncology, PLLC, Hermitage, Tennessee, United States
Tennessee Oncology, PLLC, Lebanon, Tennessee, United States
The West Clinic, PC, Memphis, Tennessee, United States
The West Clinic, PC, Memphis, Tennessee, United States
Tennessee Oncology, PLLC, Murfreesboro, Tennessee, United States
Tennessee Oncology, PLLC, Nashville, Tennessee, United States
The Sarah Cannon Research Institute, Nashville, Tennessee, United States
Vanderbilt Breast Center at One Hundred Oaks, Nashville, Tennessee, United States
Vanderbilt Health Pharmacy One Hundred Oaks, Nashville, Tennessee, United States
Tennessee Oncology, PLLC, Nashville, Tennessee, United States
Tennessee Oncology, PLLC, Nashville, Tennessee, United States
Tennessee Oncology, PLLC, Nashville, Tennessee, United States
Henry-Joyce Cancer Clinic, Nashville, Tennessee, United States
Tennessee Oncology, PLLC, Smyrna, Tennessee, United States
Texas Oncology-Baylor Charles A. Sammons Cancer Center, Dallas, Texas, United States
Texas Oncology - Longview Cancer Center, Longview, Texas, United States
Texas Oncology-Tyler, Tyler, Texas, United States
Virginia Cancer Institute, Mechanicsville, Virginia, United States
Virginia Cancer Institute, Midlothian, Virginia, United States
Virginia Oncology Associates, Newport News, Virginia, United States
Virginia Oncology Associates, Norfolk, Virginia, United States
Virginia Cancer Institute, Richmond, Virginia, United States
Virginia Cancer Institute, Richmond, Virginia, United States
Virginia Oncology Associates, Virginia Beach, Virginia, United States
Institut Jules Bordet, Brussels, , Belgium
British Columbia Cancer Agency - Vancouver Centre, Vancouver, British Columbia, Canada
Sunnybrook Research Institute, Toronto, Ontario, Canada
McGill University Health Centre-Cedars Cancer Centre, Montreal, Quebec, Canada
Pharmacy Department, Dublin 4, , Ireland
3rd Floor,Oncology Link office, Dublin, , Ireland
Department of Radiology, Dublin, , Ireland
Institute for Cancer Research, Dublin, , Ireland
Mater Private Hospital, Dublin, , Ireland
Pharmacy Department, Dublin, , Ireland
Radiology Department, Dublin, , Ireland
U.O Farmaceutica, Nuovo Ospedale di Prato Palazzina dei servizi, Prato, , Italy
Hospital Universitario HM Monteprincipe, Boadilla del Monte, Madrid, Spain
Grupo Hospitalario Quiron - Hospital Quiron Barcelona, Barcelona, , Spain
Hospital Universitari Vall d'Hebron, Barcelona, , Spain
Hospital Universitario Ramon Y Cajal, Madrid, , Spain
Hospital Universitario 12 Octubre, Madrid, , Spain
Centro Intergral Oncologico Clara Campal, Madrid, , Spain
Hospital de Madrid Norte-Sanchinarro., Madrid, , Spain
Clinical Investigation and Research Unit, Brighton, England, United Kingdom
Pharmacy Department, Brighton, England, United Kingdom
Radiation Safety Service, Medical Physics Department, Brighton, England, United Kingdom
Histopathology Department, Nottingham, England, United Kingdom
Nottingham University Hospital, Nottingham, England, United Kingdom
Pharmacy Department, Nottingham, England, United Kingdom
Radiology Department, Nottingham, England, United Kingdom
Royal Cornwall Hospitals NHS trust, Truro, Cornwall, England, United Kingdom
Department of Radiology, Truro, England, United Kingdom
Pharmacy Department, Truro, England, United Kingdom
Name: Pfizer CT.gov Call Center
Affiliation: Pfizer
Role: STUDY_DIRECTOR
Name: Pfizer CT.gov Call Center
Affiliation: Pfizer
Role: STUDY_CHAIR