Spots Global Cancer Trial Database for FS222 First in Human Study in Patients With Advanced Malignancies
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
Trial Identification
Brief Title: FS222 First in Human Study in Patients With Advanced Malignancies
Official Title: A Phase 1, Open-Label, First-in-Human Study to Evaluate the Safety and Anti-tumour Activity of FS222, a CD137/PD-L1 Bispecific Antibody, in Subjects With Advanced Malignancies
Study ID: NCT04740424
Interventions
Study Description
Brief Summary: This study will be conducted in adult participants diagnosed with advanced tumours to characterize the safety, tolerability, pharmacokinetics (PK), and activity of FS222. This is a Phase 1, multi-center, open label, multiple-dose, first in human study, designed to systematically assess safety and tolerability, and to identify the maximum tolerated dose (MTD) and/or recommended Phase 2 dose (RP2D) for FS222 in participants with advanced tumours. Pharmacokinetics, pharmacodynamics, immunogenicity, and response will also be assessed.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Arensia Exploratory Medicine, LLC, Tbilisi, , Georgia
Prof. Dr. Alexandru Trestioreanu Oncologic Institute, Bucharest, , Romania
"Dr. Carol Davila" Nephrology Clinical Hospital, Bucharest, , Romania
Prof Dr I Chiricuta Institute of Oncology, Cluj-Napoca, , Romania
Clinica Universidad Navarra, Pamplona, Navarra, Spain
NEXT - Hospital Quironsalud Barcelona, Barcelona, , Spain
Hospital Universitari Vall D'Hebron, Barcelona, , Spain
Hospital Clinic de Barcelona, Barcelona, , Spain
Institut Catala d'Oncologia de Badalona, Barcelona, , Spain
Complejo Hospitalario Universitario Insular-Materno Infantil, Las Palmas De Gran Canaria, , Spain
Instituto de Investigación Sanitaria Fundación Jimenez Díaz, Madrid, , Spain
Hospital Universitario 12 De Octubre, Madrid, , Spain
NEXT - Hospital Universitario Quironsalud Madrid, Madrid, , Spain
Hospital Universitario Puerta de Hierro - Majadahonda, Majadahonda, , Spain
Universitary Hospital Virgen Macarena, Seville, , Spain
Hospital Clinico Universitario de Valencia, Valencia, , Spain
Contact Details
Take Control of Your Skin and Body Changes Today.
Try out Spots for free, set up only takes 2 mins.
Join others from around the world:
