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Spots Global Cancer Trial Database for metastatic cancer

Every month we try and update this database with for metastatic cancer cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study titleNCT IDConditionsInterventionsEligibilityOrganizationLink
Radiation Therapy Combined With Either Gefitinib or Temozolomide in Pats With NSCLC and Brain MetastasesNCT00238251
Lung Cancer
Metastatic Canc...
gefitinib
temozolomide
radiation thera...
18 Years - Swiss Group for Clinical Cancer Research
Thiopurine Enhanced Mutations for PD-1/Ligand-1 EfficacyNCT05276284
Solid Tumor, Ad...
Metastatic Canc...
Atezolizumab, 6...
18 Years - Rigshospitalet, Denmark
Everolimus and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastasis From Non-Small Cell Lung CancerNCT00892801
Lung Cancer
Metastatic Canc...
RAD001
whole-brain rad...
18 Years - Vanderbilt-Ingram Cancer Center
Study Comparing Standard of Care Chemotherapy With/ Without Sequential Cytoreductive Surgery for Patients With Metastatic Foregut Cancer and Undetectable Circulating Tumor-Deoxyribose Nucleic Acid LevelsNCT04931420
Metastatic Canc...
Foregut Carcino...
Gastric Adenoca...
Gallbladder Ade...
Liver Cancer
GI Cancer
GI Carcinoma
Lung Cancer
Standard of Car...
Video-Assisted ...
Lobectomy
Consolidative R...
Ablation Treatm...
Resection or Ex...
Peritonectomy
Transarterial R...
18 Years - University of Chicago
Electronic Patient Reporting of Symptoms During Cancer TreatmentNCT03249090
Metastatic Canc...
Patient Self-Re...
Usual Care Deli...
21 Years - Alliance Foundation Trials, LLC.
Hepatic Arterial Infusion With Floxuridine and Dexamethasone Combined With Combination Chemotherapy in Treating Patients With Colorectal Cancer That Has Spread to the LiverNCT00492999
Colorectal Canc...
Metastatic Canc...
dexamethasone
floxuridine
fluorouracil
irinotecan hydr...
leucovorin calc...
oxaliplatin
18 Years - 120 YearsMemorial Sloan Kettering Cancer Center
Boron Neutron Capture Therapy in Treating Patients With Glioblastoma Multiforme or Melanoma Metastatic to the BrainNCT00039572
Brain and Centr...
Melanoma (Skin)
Metastatic Canc...
boronophenylala...
18 Years - National Cancer Institute (NCI)
Pharmacokinetic and Safety Study of MRX-2843 in Adults With Relapsed/Refractory Advanced and/or Metastatic Solid TumorsNCT03510104
Advanced Cancer
Metastatic Canc...
Neoplasms
Neoplasm Metast...
Neoplastic Proc...
Pathologic Proc...
MRX-2843
18 Years - Meryx, Inc.
Patient Reported Outcomes/Metrics Program TrialNCT04983199
Metastatic Canc...
Palliative
Hexoskin Medica...
18 Years - University Health Network, Toronto
An Open Label Phase II Study Combining Nivolumab and Celecoxib in Patients With Advanced " Cold " Solid TumorsNCT03864575
Metastatic Canc...
Celecoxib 400 m...
18 Years - Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Genetically-informed Therapies for Patients With Metastatic CancerNCT02000739
Metastatic Canc...
Genetically Inf...
18 Years - Dartmouth-Hitchcock Medical Center
Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Men With Previously Untreated Germ Cell CancerNCT00003941
Mediastinal Can...
Metastatic Canc...
Testicular Germ...
bleomycin sulfa...
filgrastim
cisplatin
etoposide
ifosfamide
bone marrow abl...
peripheral bloo...
16 Years - 50 YearsEuropean Organisation for Research and Treatment of Cancer - EORTC
Zoledronate in Preventing Skeletal (Bone)-Related Events in Men Who Are Receiving Androgen Deprivation Therapy For Prostate Cancer and Bone MetastasesNCT00079001
Metastatic Canc...
Prostate Cancer
zoledronic acid
placebo
androgen depriv...
GnRH agonist
Calcium supplem...
Vitamin D
18 Years - Alliance for Clinical Trials in Oncology
Genetically-informed Therapies for Patients With Metastatic CancerNCT02000739
Metastatic Canc...
Genetically Inf...
18 Years - Dartmouth-Hitchcock Medical Center
T Cell Receptor Immunotherapy Targeting NY-ESO-1 for Patients With NY-ESO-1 Expressing MelanomaNCT02062359
Metastatic Canc...
Metastatic Mela...
Anti-NY ESO-1 T...
Aldesleukin
Cyclophosphamid...
Fludarabine
18 Years - 70 YearsNational Institutes of Health Clinical Center (CC)
In Vitro Functional Modulation of Monocyte-derived Dendritic Cells of Patients With Cancer by PeptidesNCT02159937
Metastatic Canc...
Blood sampling ...
18 Years - Recepta Biopharma
Metastatic Solid Cancer Clinical TrialNCT04739618
Metastatic Canc...
Keytruda Inject...
Yervoy Injectab...
GM-CSF
Non-ablative Cr...
18 Years - ImmunSYS, LLC
Role of Ablative Radiotherapy in the Management of Metastatic Disease: A Patient Data RegistryNCT04085029
Oligometastasis
Metastatic Canc...
18 Years - Duke University
Abiraterone, Enzalutamide, or Apalutamide in Castrate-sensitive Prostate Cancer.NCT05422911
Metastatic Canc...
Neoplasm, Prost...
Abiraterone ace...
Apalutamide
Enzalutamide
- James J. Peters Veterans Affairs Medical Center
Docetaxel-polymeric Micelles(PM) and Oxaliplatin for Esophageal CarcinomaNCT03585673
Esophagus Squam...
Metastatic Canc...
Docetaxel-PM
Oxaliplatin
18 Years - Dong-A University Hospital
Temozolomide in Treating Patients With Primary Brain Tumors or Metastatic Brain TumorsNCT00547131
Brain and Centr...
Metastatic Canc...
temozolomide
laboratory biom...
liquid chromato...
mass spectromet...
pharmacological...
conventional su...
stereotactic ra...
18 Years - 120 YearsCity of Hope Medical Center
A Study of ART4215 for the Treatment of Advanced or Metastatic Solid TumorsNCT04991480
Advanced Cancer
Metastatic Canc...
Breast Cancer
ART4215
Talazoparib
Niraparib
18 Years - Artios Pharma Ltd
Stereotactic Radiosurgery in Treating Patients With Spinal MetastasesNCT00853528
Metastatic Canc...
questionnaire a...
diffusion tenso...
functional magn...
hypo-fractionat...
single-fraction...
18 Years - Boston Medical Center
Impact on Quality of Life and Health of the CONTINUUM+ CONNECT Remote Monitoring SolutionNCT06379880
Prostatic Neopl...
Lung Neoplasms
Breast Neoplasm...
Colorectal Neop...
CONTINUUM+ CONN...
18 Years - Institut de cancérologie Strasbourg Europe
A Study of NTX-1088, a Monoclonal Antibody Targeting the Poliovirus Receptor (PVR, CD155), as Monotherapy and Combined With PembrolizumabNCT05378425
Cancer
Tumor, Solid
Advanced Solid ...
Metastatic Canc...
Locally Advance...
NTX-1088
Pembrolizumab
18 Years - Nectin Therapeutics Ltd
Improving End-of-life Care by Continuing Medical Education and Electronic Decision Making Support for General PractitionersNCT02050256
Chronic Obstruc...
Metastatic Canc...
continuing medi...
education and e...
- University of Aarhus
Efficacy of Point Of Service Testing in MBCNCT03983577
Metastatic Canc...
Breast Cancer
Point of servic...
18 Years - University of Kansas Medical Center
Study of Pembrolizumab, Binimetinib, and Bevacizumab in Patients With Refractory Colorectal CancerNCT03475004
Colorectal Canc...
Metastatic Canc...
Pembrolizumab
Bevacizumab
Binimetinib
18 Years - 99 YearsUniversity of Colorado, Denver
Immunotherapy in Patients With Metastatic Cancers and CDK12 MutationsNCT03570619
Metastatic Cast...
Metastatic Canc...
Solid Tumor
Nivolumab
Ipilimumab
18 Years - University of Michigan Rogel Cancer Center
UNC Metastatic Cancer Radiation Therapy RegistryNCT06306924
Cancer
Metastatic Canc...
Radiation thera...
18 Years - UNC Lineberger Comprehensive Cancer Center
CAR-macrophages for the Treatment of HER2 Overexpressing Solid TumorsNCT04660929
HER2-positive
Adenocarcinoma
Bile Duct Cance...
Biliary Tract C...
Bladder Cancer
Breast Cancer
Breast Neoplasm
Carcinoma, Duct...
Carcinoma, Hepa...
Cancer
Lung Cancer, No...
Carcinoma, Ovar...
Carcinoma, Smal...
Carcinoma, Squa...
Carcinoma, Tran...
Colorectal Canc...
Esophagogastric...
Inflammatory Br...
Stomach Neoplas...
Malignant Neopl...
Ovarian Neoplas...
Pancreatic Canc...
HER2-positive S...
HER2-positive B...
HER2-positive G...
HER-2 Protein O...
HER-2 Gene Ampl...
Prostate Cancer
Head and Neck C...
Endometrial Can...
Lung Cancer, Sm...
CT-0508
Pembrolizumab
18 Years - Carisma Therapeutics Inc
Laboratory-Treated Autologous Lymphocytes, Aldesleukin, and Sargramostim (GM-CSF) in Treating Advanced Solid TumorsNCT01081808
Neoplasms
Tumors
Solid Tumors
Metastatic Canc...
EGFRBi-armed au...
18 Years - Roger Williams Medical Center
Investigation of the Timely-coordinated Therapy of Patients With Metastatic Cancer by Radiotherapy Together With Immune Checkpoint InhibitionNCT03453892
Metastatic Canc...
Nivolumab
Pembrolizumab
Radiotherapy
Ipilimumab
18 Years - University of Erlangen-Nürnberg Medical School
Radiation Therapy With or Without Radiosurgery in Treating Patients With Brain MetastasesNCT00002708
Metastatic Canc...
surgical proced...
radiation thera...
stereotactic ra...
18 Years - Radiation Therapy Oncology Group
Study of ART6043 in Advanced/Metastatic Solid Tumors PatientsNCT05898399
Advanced Solid ...
Metastatic Soli...
ART6043
Olaparib
Niraparib
Olaparib
Niraparib
18 Years - Artios Pharma Ltd
Personalized Oncogenomics (POG) Program of British ColumbiaNCT02155621
Metastatic Canc...
Advanced Cancer...
Cancers That Ca...
Genome sequenci...
18 Years - 85 YearsBritish Columbia Cancer Agency
A First-in-human (FIH), Multicenter, Open-Label, Phase I Study of PTX-912 in Patients With Locally Advanced/Metastatic Solid TumorsNCT06190886
Advanced Cancer
Solid Tumor
Metastatic Canc...
PTX-912
18 Years - Proviva Therapeutics, Inc.
A Study of CriPec® Docetaxel Given to Patients With Solid TumoursNCT02442531
Cancer
Metastatic Canc...
Solid Tumors
CriPec® docetax...
18 Years - Cristal Therapeutics
Clinical Sequencing Project for Metastatic Cancer Patients for Personalized Cancer Clinic.NCT02593578
Metastatic Canc...
19 Years - Samsung Medical Center
QUILT-2.014: Gemcitabine and AMG 479 in Metastatic Adenocarcinoma of the PancreasNCT01231347
Adenocarcinoma ...
Advanced Solid ...
Cancer
Cancer of Pancr...
Cancer of the P...
Metastases
Metastatic Canc...
Metastatic Panc...
Pancreas Cancer
Pancreatic Canc...
Bone Metastases
Endocrine Cance...
Oncology
Oncology Patien...
Solid Tumors
Advanced Malign...
AMG 479
Placebo
AMG 479
gemcitabine
18 Years - NantCell, Inc.
Study of Circulating Tumor DNA (ctDNA) Kinetics in Immuno-oncology (IO-KIN)NCT04606940
Head and Neck C...
Advanced Cancer
Metastatic Canc...
HNSCC
Squamous Cell C...
18 Years - University Health Network, Toronto
Tumor Cell Vaccines and ISCOMATRIX With Chemotherapy After Tumor RemovalNCT01341496
Sarcoma
Melanoma
Epithelial Mali...
Pleural Maligna...
Epigenetically ...
Cyclophosphamid...
Celecoxib
18 Years - 99 YearsNational Institutes of Health Clinical Center (CC)
Dexmedetomidine Addition to Morphine in Patients With Metastatic CancerNCT03936205
Refractory Pain
Metastatic Canc...
Dexmedetomidine
18 Years - 75 YearsHotel Dieu de France Hospital
Imaging of Solid Tumors Using FAP-2286NCT04621435
Solid Tumors, A...
Metastatic Canc...
Gallium-68 labe...
Positron Emissi...
Copper-64 label...
18 Years - University of California, San Francisco
A Study of ARRY-382 in Patients With Selected Advanced or Metastatic CancersNCT01316822
Metastatic Canc...
ARRY-382, cFMS ...
18 Years - Array BioPharma
Study of TJ210001 Administered in Subjects With Relapsed or Refractory Advanced Solid TumorsNCT04678921
Solid Tumor
Metastatic Canc...
Advanced Cancer
TJ210001
18 Years - 99 YearsI-Mab Biopharma US Limited
Stereotactic Radiosurgery in Treating Patients With Brain MetastasesNCT00811655
Metastatic Canc...
Unspecified Adu...
therapeutic con...
stereotactic ra...
18 Years - Duke University
S0308 Zoledronate or Ibandronate in Preventing Bone Problems in Women With Stage IV Breast Cancer That Has Spread to the BoneNCT00301886
Breast Cancer
Hypercalcemia o...
Metastatic Canc...
Pain
ibandronate
zoledronate
quality-of-life...
18 Years - SWOG Cancer Research Network
A Study of INCAGN01876 in Participants With Advanced or Metastatic Solid TumorsNCT02697591
Advanced Malign...
Metastatic Canc...
INCAGN01876
18 Years - Incyte Corporation
Advanced Planning for Online Accounts and DataNCT05222308
Terminal Cancer
Metastatic Canc...
Post-Mortem Pla...
18 Years - 100 YearsUniversity of Colorado, Denver
A Study of OMP-336B11 in Subjects With Locally Advanced or Metastatic TumorsNCT03295942
Locally Advance...
Metastatic Canc...
OMP-336B11
21 Years - Mereo BioPharma
Study of Erlotinib in Combination With BortezomibNCT00895687
Advanced Cancer
Erlotinib Hydro...
Bortezomib
- M.D. Anderson Cancer Center
Combination Chemotherapy With or Without Cetuximab Before and After Surgery in Treating Patients With Resectable Liver Metastases Caused By Colorectal CancerNCT00482222
Colorectal Canc...
Metastatic Canc...
cetuximab
capecitabine
fluorouracil
leucovorin calc...
oxaliplatin
study of socioe...
adjuvant therap...
neoadjuvant the...
quality-of-life...
18 Years - University of Southampton
CCI-779 in Treating Patients With Advanced Solid TumorsNCT00003712
Brain and Centr...
Metastatic Canc...
Unspecified Adu...
temsirolimus
18 Years - The University of Texas Health Science Center at San Antonio
Trial-specific Patient Decision Aid (tPDA) of the ImmunoSABR Phase 2NCT04604470
NSCLC Stage IV
Lung Cancer
Non Small Cell ...
Metastatic Canc...
Decision tool
18 Years - Maastricht University
Stereotactic Ablative Radiotherapy for Oligo-Progressive Disease REfractory to Systemic Therapy in Metastatic CancerNCT04989725
Head and Neck C...
Metastatic Canc...
Oligoprogressiv...
Standard arm
Experimental ar...
18 Years - Centre hospitalier de l'Université de Montréal (CHUM)
Biological Therapy in Treating Women With Breast Cancer That Has Spread to the LiverNCT00301106
Breast Cancer
Metastatic Canc...
adenovirus-medi...
18 Years - 85 YearsIcahn School of Medicine at Mount Sinai
Optimizing Y90 Therapy for Radiation LobectomyNCT04390724
HCC
Resection
Transplant
Metastatic Canc...
Adult Primary L...
Y90 radioemboli...
18 Years - Northwestern University
A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.NCT06022029
Triple Negative...
Diffuse Large B...
Follicular Lymp...
Lymphoma, Non-H...
Mantle Cell Lym...
Bladder Cancer
Uveal Melanoma,...
Cervix Cancer
Carcinoma in Si...
Head and Neck S...
Skin Cancer
Metastatic Canc...
Tumor, Solid
Tumor Recurrenc...
ONM-501
Cemiplimab
18 Years - OncoNano Medicine, Inc.
Study of FOLFIRI Plus Cetuximab Plus IMO-2055 in Patients With Colorectal CancerNCT00719199
Colorectal Canc...
IMO-2055
Cetuximab
FOLFIRI
18 Years - EMD Serono
A Dose-escalation Study in Subjects With Advanced MalignanciesNCT01072266
Solid Tumor
Advanced Cancer
Metastatic Canc...
INCB028060
18 Years - Incyte Corporation
A Study of OMP-336B11 in Subjects With Locally Advanced or Metastatic TumorsNCT03295942
Locally Advance...
Metastatic Canc...
OMP-336B11
21 Years - Mereo BioPharma
Combination Chemotherapy Before or After Surgery in Treating Patients With Colorectal Cancer With Liver Metastases That Could Be Removed By SurgeryNCT01189227
Colorectal Canc...
Metastatic Canc...
Postoperative c...
Perioperative c...
18 Years - NSABP Foundation Inc
Non-invasive Measurement of PD-L1 Levels With Positron Emission Tomography (PET) in Head and Neck Malignancies and Intracranial MetastasesNCT05408871
Cancer Head Nec...
Metastatic Canc...
Metastatic Lung...
adnectin 18F-BM...
adnectin 18F-BM...
18 Years - Yale University
Stereotactic Radiosurgery (SRS) for Multiple CNS MetsNCT02567643
Metastatic Canc...
Brain Metastase...
Stereotactic Ra...
- The Cooper Health System
Doxil, Bevacizumab and Temsirolimus TrialNCT00761644
Advanced Cancer
Doxil
Bevacizumab
Temsirolimus
12 Years - M.D. Anderson Cancer Center
A Phase 2 Trial for Patients With Metastatic Solid CancerNCT04713371
Metastatic Canc...
Keytruda Inject...
Yervoy Injectab...
Cytoxan
Cryosurgical fr...
GM-CSF Injectab...
18 Years - Rampart Health, L.L.C.
Doxil, Bevacizumab and Temsirolimus TrialNCT00761644
Advanced Cancer
Doxil
Bevacizumab
Temsirolimus
12 Years - M.D. Anderson Cancer Center
Paclitaxel and Hyperthermic Perfusion in Treating Patients With Lung Cancer or Lung Metastases That Cannot Be Removed By SurgeryNCT00020007
Lung Cancer
Metastatic Canc...
isolated perfus...
paclitaxel
hyperthermia tr...
18 Years - National Cancer Institute (NCI)
Matrix Metalloproteinases After Surgery and/or Radiofrequency Ablation in Patients With Liver Metastases From Colorectal CancerNCT00899210
Colorectal Canc...
Metastatic Canc...
laboratory biom...
cryosurgery
radiofrequency ...
therapeutic con...
18 Years - National Cancer Institute (NCI)
Photodynamic Therapy With Porfimer Sodium in Treating Patients With Refractory Brain TumorsNCT00002647
Brain and Centr...
Metastatic Canc...
verteporfin
conventional su...
3 Years - 70 YearsNational Cancer Institute (NCI)
FOLFIRI Alternate With FOLFOX in Untreated Metastatic Gastric and Esophageal AdenocarcinomaNCT03528876
Metastatic Gast...
FOLFOX and FOLF...
18 Years - University of Saskatchewan
Study of Avutometinib (VS-6766) + Adagrasib in KRAS G12C NSCLC PatientsNCT05375994
Non Small Cell ...
KRAS Activating...
Advanced Cancer
Metastatic Canc...
Malignant Neopl...
Malignant Neopl...
avutometinib (V...
18 Years - Verastem, Inc.
Chemotherapy and Bevacizumab With or Without Radiofrequency Ablation in Treating Unresectable Liver Metastases in Patients With Colorectal CancerNCT00043004
Colorectal Canc...
Metastatic Canc...
bevacizumab
FOLFOX regimen
fluorouracil
leucovorin calc...
oxaliplatin
conventional su...
radiofrequency ...
18 Years - 80 YearsEuropean Organisation for Research and Treatment of Cancer - EORTC
Modified Tumor Infiltrating Lymphocytes for Metastatic MelanomaNCT01369875
Metastatic Mela...
Skin Cancer
Cyclophosphamid...
Fludarabine
Aldesleukin
Tumor Infiltrat...
18 Years - National Institutes of Health Clinical Center (CC)
Metastatic Pathologic Fractures, Short Term ResultsNCT05825456
Pathologic Frac...
Bone Metastases
Metastatic Canc...
endoprosthetic ...
Intramedullary ...
Open reduction ...
- Ankara University
Surgery With or Without Combination Chemotherapy in Treating Patients With Lung Metastases From Soft Tissue SarcomaNCT00002764
Endometrial Can...
Kidney Cancer
Metastatic Canc...
Ovarian Cancer
Pheochromocytom...
Sarcoma
filgrastim
doxorubicin hyd...
ifosfamide
conventional su...
16 Years - European Organisation for Research and Treatment of Cancer - EORTC
Triage of Advanced Cervical Cancer Through Immunotherapy Induction (TRACTION)NCT05475171
Metastatic Canc...
Cervical Cancer
MGD019
18 Years - M.D. Anderson Cancer Center
Harvesting Cells for Experimental Cancer TreatmentsNCT00068003
Melanoma
Gastrointestina...
Metastatic Canc...
Breast Cancer
Non-Small Cell ...
Anti-CD19 CAR P...
18 Years - National Institutes of Health Clinical Center (CC)
A Study of ART4215 for the Treatment of Advanced or Metastatic Solid TumorsNCT04991480
Advanced Cancer
Metastatic Canc...
Breast Cancer
ART4215
Talazoparib
Niraparib
18 Years - Artios Pharma Ltd
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