Spots Global Cancer Trial Database for metastatic cancer
Every month we try and update this database with for metastatic cancer cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
---|---|---|---|---|---|---|
Radiation Therapy Combined With Either Gefitinib or Temozolomide in Pats With NSCLC and Brain Metastases | NCT00238251 | Lung Cancer Metastatic Canc... | gefitinib temozolomide radiation thera... | 18 Years - | Swiss Group for Clinical Cancer Research | |
Thiopurine Enhanced Mutations for PD-1/Ligand-1 Efficacy | NCT05276284 | Solid Tumor, Ad... Metastatic Canc... | Atezolizumab, 6... | 18 Years - | Rigshospitalet, Denmark | |
Everolimus and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastasis From Non-Small Cell Lung Cancer | NCT00892801 | Lung Cancer Metastatic Canc... | RAD001 whole-brain rad... | 18 Years - | Vanderbilt-Ingram Cancer Center | |
Study Comparing Standard of Care Chemotherapy With/ Without Sequential Cytoreductive Surgery for Patients With Metastatic Foregut Cancer and Undetectable Circulating Tumor-Deoxyribose Nucleic Acid Levels | NCT04931420 | Metastatic Canc... Foregut Carcino... Gastric Adenoca... Gallbladder Ade... Liver Cancer GI Cancer GI Carcinoma Lung Cancer | Standard of Car... Video-Assisted ... Lobectomy Consolidative R... Ablation Treatm... Resection or Ex... Peritonectomy Transarterial R... | 18 Years - | University of Chicago | |
Electronic Patient Reporting of Symptoms During Cancer Treatment | NCT03249090 | Metastatic Canc... | Patient Self-Re... Usual Care Deli... | 21 Years - | Alliance Foundation Trials, LLC. | |
Hepatic Arterial Infusion With Floxuridine and Dexamethasone Combined With Combination Chemotherapy in Treating Patients With Colorectal Cancer That Has Spread to the Liver | NCT00492999 | Colorectal Canc... Metastatic Canc... | dexamethasone floxuridine fluorouracil irinotecan hydr... leucovorin calc... oxaliplatin | 18 Years - 120 Years | Memorial Sloan Kettering Cancer Center | |
Boron Neutron Capture Therapy in Treating Patients With Glioblastoma Multiforme or Melanoma Metastatic to the Brain | NCT00039572 | Brain and Centr... Melanoma (Skin) Metastatic Canc... | boronophenylala... | 18 Years - | National Cancer Institute (NCI) | |
Pharmacokinetic and Safety Study of MRX-2843 in Adults With Relapsed/Refractory Advanced and/or Metastatic Solid Tumors | NCT03510104 | Advanced Cancer Metastatic Canc... Neoplasms Neoplasm Metast... Neoplastic Proc... Pathologic Proc... | MRX-2843 | 18 Years - | Meryx, Inc. | |
Patient Reported Outcomes/Metrics Program Trial | NCT04983199 | Metastatic Canc... Palliative | Hexoskin Medica... | 18 Years - | University Health Network, Toronto | |
An Open Label Phase II Study Combining Nivolumab and Celecoxib in Patients With Advanced " Cold " Solid Tumors | NCT03864575 | Metastatic Canc... | Celecoxib 400 m... | 18 Years - | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | |
Genetically-informed Therapies for Patients With Metastatic Cancer | NCT02000739 | Metastatic Canc... | Genetically Inf... | 18 Years - | Dartmouth-Hitchcock Medical Center | |
Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Men With Previously Untreated Germ Cell Cancer | NCT00003941 | Mediastinal Can... Metastatic Canc... Testicular Germ... | bleomycin sulfa... filgrastim cisplatin etoposide ifosfamide bone marrow abl... peripheral bloo... | 16 Years - 50 Years | European Organisation for Research and Treatment of Cancer - EORTC | |
Zoledronate in Preventing Skeletal (Bone)-Related Events in Men Who Are Receiving Androgen Deprivation Therapy For Prostate Cancer and Bone Metastases | NCT00079001 | Metastatic Canc... Prostate Cancer | zoledronic acid placebo androgen depriv... GnRH agonist Calcium supplem... Vitamin D | 18 Years - | Alliance for Clinical Trials in Oncology | |
Genetically-informed Therapies for Patients With Metastatic Cancer | NCT02000739 | Metastatic Canc... | Genetically Inf... | 18 Years - | Dartmouth-Hitchcock Medical Center | |
T Cell Receptor Immunotherapy Targeting NY-ESO-1 for Patients With NY-ESO-1 Expressing Melanoma | NCT02062359 | Metastatic Canc... Metastatic Mela... | Anti-NY ESO-1 T... Aldesleukin Cyclophosphamid... Fludarabine | 18 Years - 70 Years | National Institutes of Health Clinical Center (CC) | |
In Vitro Functional Modulation of Monocyte-derived Dendritic Cells of Patients With Cancer by Peptides | NCT02159937 | Metastatic Canc... | Blood sampling ... | 18 Years - | Recepta Biopharma | |
Metastatic Solid Cancer Clinical Trial | NCT04739618 | Metastatic Canc... | Keytruda Inject... Yervoy Injectab... GM-CSF Non-ablative Cr... | 18 Years - | ImmunSYS, LLC | |
Role of Ablative Radiotherapy in the Management of Metastatic Disease: A Patient Data Registry | NCT04085029 | Oligometastasis Metastatic Canc... | 18 Years - | Duke University | ||
Abiraterone, Enzalutamide, or Apalutamide in Castrate-sensitive Prostate Cancer. | NCT05422911 | Metastatic Canc... Neoplasm, Prost... | Abiraterone ace... Apalutamide Enzalutamide | - | James J. Peters Veterans Affairs Medical Center | |
Docetaxel-polymeric Micelles(PM) and Oxaliplatin for Esophageal Carcinoma | NCT03585673 | Esophagus Squam... Metastatic Canc... | Docetaxel-PM Oxaliplatin | 18 Years - | Dong-A University Hospital | |
Temozolomide in Treating Patients With Primary Brain Tumors or Metastatic Brain Tumors | NCT00547131 | Brain and Centr... Metastatic Canc... | temozolomide laboratory biom... liquid chromato... mass spectromet... pharmacological... conventional su... stereotactic ra... | 18 Years - 120 Years | City of Hope Medical Center | |
A Study of ART4215 for the Treatment of Advanced or Metastatic Solid Tumors | NCT04991480 | Advanced Cancer Metastatic Canc... Breast Cancer | ART4215 Talazoparib Niraparib | 18 Years - | Artios Pharma Ltd | |
Stereotactic Radiosurgery in Treating Patients With Spinal Metastases | NCT00853528 | Metastatic Canc... | questionnaire a... diffusion tenso... functional magn... hypo-fractionat... single-fraction... | 18 Years - | Boston Medical Center | |
Impact on Quality of Life and Health of the CONTINUUM+ CONNECT Remote Monitoring Solution | NCT06379880 | Prostatic Neopl... Lung Neoplasms Breast Neoplasm... Colorectal Neop... | CONTINUUM+ CONN... | 18 Years - | Institut de cancérologie Strasbourg Europe | |
A Study of NTX-1088, a Monoclonal Antibody Targeting the Poliovirus Receptor (PVR, CD155), as Monotherapy and Combined With Pembrolizumab | NCT05378425 | Cancer Tumor, Solid Advanced Solid ... Metastatic Canc... Locally Advance... | NTX-1088 Pembrolizumab | 18 Years - | Nectin Therapeutics Ltd | |
Improving End-of-life Care by Continuing Medical Education and Electronic Decision Making Support for General Practitioners | NCT02050256 | Chronic Obstruc... Metastatic Canc... | continuing medi... education and e... | - | University of Aarhus | |
Efficacy of Point Of Service Testing in MBC | NCT03983577 | Metastatic Canc... Breast Cancer | Point of servic... | 18 Years - | University of Kansas Medical Center | |
Study of Pembrolizumab, Binimetinib, and Bevacizumab in Patients With Refractory Colorectal Cancer | NCT03475004 | Colorectal Canc... Metastatic Canc... | Pembrolizumab Bevacizumab Binimetinib | 18 Years - 99 Years | University of Colorado, Denver | |
Immunotherapy in Patients With Metastatic Cancers and CDK12 Mutations | NCT03570619 | Metastatic Cast... Metastatic Canc... Solid Tumor | Nivolumab Ipilimumab | 18 Years - | University of Michigan Rogel Cancer Center | |
UNC Metastatic Cancer Radiation Therapy Registry | NCT06306924 | Cancer Metastatic Canc... | Radiation thera... | 18 Years - | UNC Lineberger Comprehensive Cancer Center | |
CAR-macrophages for the Treatment of HER2 Overexpressing Solid Tumors | NCT04660929 | HER2-positive Adenocarcinoma Bile Duct Cance... Biliary Tract C... Bladder Cancer Breast Cancer Breast Neoplasm Carcinoma, Duct... Carcinoma, Hepa... Cancer Lung Cancer, No... Carcinoma, Ovar... Carcinoma, Smal... Carcinoma, Squa... Carcinoma, Tran... Colorectal Canc... Esophagogastric... Inflammatory Br... Stomach Neoplas... Malignant Neopl... Ovarian Neoplas... Pancreatic Canc... HER2-positive S... HER2-positive B... HER2-positive G... HER-2 Protein O... HER-2 Gene Ampl... Prostate Cancer Head and Neck C... Endometrial Can... Lung Cancer, Sm... | CT-0508 Pembrolizumab | 18 Years - | Carisma Therapeutics Inc | |
Laboratory-Treated Autologous Lymphocytes, Aldesleukin, and Sargramostim (GM-CSF) in Treating Advanced Solid Tumors | NCT01081808 | Neoplasms Tumors Solid Tumors Metastatic Canc... | EGFRBi-armed au... | 18 Years - | Roger Williams Medical Center | |
Investigation of the Timely-coordinated Therapy of Patients With Metastatic Cancer by Radiotherapy Together With Immune Checkpoint Inhibition | NCT03453892 | Metastatic Canc... | Nivolumab Pembrolizumab Radiotherapy Ipilimumab | 18 Years - | University of Erlangen-Nürnberg Medical School | |
Radiation Therapy With or Without Radiosurgery in Treating Patients With Brain Metastases | NCT00002708 | Metastatic Canc... | surgical proced... radiation thera... stereotactic ra... | 18 Years - | Radiation Therapy Oncology Group | |
Study of ART6043 in Advanced/Metastatic Solid Tumors Patients | NCT05898399 | Advanced Solid ... Metastatic Soli... | ART6043 Olaparib Niraparib Olaparib Niraparib | 18 Years - | Artios Pharma Ltd | |
Personalized Oncogenomics (POG) Program of British Columbia | NCT02155621 | Metastatic Canc... Advanced Cancer... Cancers That Ca... | Genome sequenci... | 18 Years - 85 Years | British Columbia Cancer Agency | |
A First-in-human (FIH), Multicenter, Open-Label, Phase I Study of PTX-912 in Patients With Locally Advanced/Metastatic Solid Tumors | NCT06190886 | Advanced Cancer Solid Tumor Metastatic Canc... | PTX-912 | 18 Years - | Proviva Therapeutics, Inc. | |
A Study of CriPec® Docetaxel Given to Patients With Solid Tumours | NCT02442531 | Cancer Metastatic Canc... Solid Tumors | CriPec® docetax... | 18 Years - | Cristal Therapeutics | |
Clinical Sequencing Project for Metastatic Cancer Patients for Personalized Cancer Clinic. | NCT02593578 | Metastatic Canc... | 19 Years - | Samsung Medical Center | ||
QUILT-2.014: Gemcitabine and AMG 479 in Metastatic Adenocarcinoma of the Pancreas | NCT01231347 | Adenocarcinoma ... Advanced Solid ... Cancer Cancer of Pancr... Cancer of the P... Metastases Metastatic Canc... Metastatic Panc... Pancreas Cancer Pancreatic Canc... Bone Metastases Endocrine Cance... Oncology Oncology Patien... Solid Tumors Advanced Malign... | AMG 479 Placebo AMG 479 gemcitabine | 18 Years - | NantCell, Inc. | |
Study of Circulating Tumor DNA (ctDNA) Kinetics in Immuno-oncology (IO-KIN) | NCT04606940 | Head and Neck C... Advanced Cancer Metastatic Canc... HNSCC Squamous Cell C... | 18 Years - | University Health Network, Toronto | ||
Tumor Cell Vaccines and ISCOMATRIX With Chemotherapy After Tumor Removal | NCT01341496 | Sarcoma Melanoma Epithelial Mali... Pleural Maligna... | Epigenetically ... Cyclophosphamid... Celecoxib | 18 Years - 99 Years | National Institutes of Health Clinical Center (CC) | |
Dexmedetomidine Addition to Morphine in Patients With Metastatic Cancer | NCT03936205 | Refractory Pain Metastatic Canc... | Dexmedetomidine | 18 Years - 75 Years | Hotel Dieu de France Hospital | |
Imaging of Solid Tumors Using FAP-2286 | NCT04621435 | Solid Tumors, A... Metastatic Canc... | Gallium-68 labe... Positron Emissi... Copper-64 label... | 18 Years - | University of California, San Francisco | |
A Study of ARRY-382 in Patients With Selected Advanced or Metastatic Cancers | NCT01316822 | Metastatic Canc... | ARRY-382, cFMS ... | 18 Years - | Array BioPharma | |
Study of TJ210001 Administered in Subjects With Relapsed or Refractory Advanced Solid Tumors | NCT04678921 | Solid Tumor Metastatic Canc... Advanced Cancer | TJ210001 | 18 Years - 99 Years | I-Mab Biopharma US Limited | |
Stereotactic Radiosurgery in Treating Patients With Brain Metastases | NCT00811655 | Metastatic Canc... Unspecified Adu... | therapeutic con... stereotactic ra... | 18 Years - | Duke University | |
S0308 Zoledronate or Ibandronate in Preventing Bone Problems in Women With Stage IV Breast Cancer That Has Spread to the Bone | NCT00301886 | Breast Cancer Hypercalcemia o... Metastatic Canc... Pain | ibandronate zoledronate quality-of-life... | 18 Years - | SWOG Cancer Research Network | |
A Study of INCAGN01876 in Participants With Advanced or Metastatic Solid Tumors | NCT02697591 | Advanced Malign... Metastatic Canc... | INCAGN01876 | 18 Years - | Incyte Corporation | |
Advanced Planning for Online Accounts and Data | NCT05222308 | Terminal Cancer Metastatic Canc... | Post-Mortem Pla... | 18 Years - 100 Years | University of Colorado, Denver | |
A Study of OMP-336B11 in Subjects With Locally Advanced or Metastatic Tumors | NCT03295942 | Locally Advance... Metastatic Canc... | OMP-336B11 | 21 Years - | Mereo BioPharma | |
Study of Erlotinib in Combination With Bortezomib | NCT00895687 | Advanced Cancer | Erlotinib Hydro... Bortezomib | - | M.D. Anderson Cancer Center | |
Combination Chemotherapy With or Without Cetuximab Before and After Surgery in Treating Patients With Resectable Liver Metastases Caused By Colorectal Cancer | NCT00482222 | Colorectal Canc... Metastatic Canc... | cetuximab capecitabine fluorouracil leucovorin calc... oxaliplatin study of socioe... adjuvant therap... neoadjuvant the... quality-of-life... | 18 Years - | University of Southampton | |
CCI-779 in Treating Patients With Advanced Solid Tumors | NCT00003712 | Brain and Centr... Metastatic Canc... Unspecified Adu... | temsirolimus | 18 Years - | The University of Texas Health Science Center at San Antonio | |
Trial-specific Patient Decision Aid (tPDA) of the ImmunoSABR Phase 2 | NCT04604470 | NSCLC Stage IV Lung Cancer Non Small Cell ... Metastatic Canc... | Decision tool | 18 Years - | Maastricht University | |
Stereotactic Ablative Radiotherapy for Oligo-Progressive Disease REfractory to Systemic Therapy in Metastatic Cancer | NCT04989725 | Head and Neck C... Metastatic Canc... Oligoprogressiv... | Standard arm Experimental ar... | 18 Years - | Centre hospitalier de l'Université de Montréal (CHUM) | |
Biological Therapy in Treating Women With Breast Cancer That Has Spread to the Liver | NCT00301106 | Breast Cancer Metastatic Canc... | adenovirus-medi... | 18 Years - 85 Years | Icahn School of Medicine at Mount Sinai | |
Optimizing Y90 Therapy for Radiation Lobectomy | NCT04390724 | HCC Resection Transplant Metastatic Canc... Adult Primary L... | Y90 radioemboli... | 18 Years - | Northwestern University | |
A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas. | NCT06022029 | Triple Negative... Diffuse Large B... Follicular Lymp... Lymphoma, Non-H... Mantle Cell Lym... Bladder Cancer Uveal Melanoma,... Cervix Cancer Carcinoma in Si... Head and Neck S... Skin Cancer Metastatic Canc... Tumor, Solid Tumor Recurrenc... | ONM-501 Cemiplimab | 18 Years - | OncoNano Medicine, Inc. | |
Study of FOLFIRI Plus Cetuximab Plus IMO-2055 in Patients With Colorectal Cancer | NCT00719199 | Colorectal Canc... | IMO-2055 Cetuximab FOLFIRI | 18 Years - | EMD Serono | |
A Dose-escalation Study in Subjects With Advanced Malignancies | NCT01072266 | Solid Tumor Advanced Cancer Metastatic Canc... | INCB028060 | 18 Years - | Incyte Corporation | |
A Study of OMP-336B11 in Subjects With Locally Advanced or Metastatic Tumors | NCT03295942 | Locally Advance... Metastatic Canc... | OMP-336B11 | 21 Years - | Mereo BioPharma | |
Combination Chemotherapy Before or After Surgery in Treating Patients With Colorectal Cancer With Liver Metastases That Could Be Removed By Surgery | NCT01189227 | Colorectal Canc... Metastatic Canc... | Postoperative c... Perioperative c... | 18 Years - | NSABP Foundation Inc | |
Non-invasive Measurement of PD-L1 Levels With Positron Emission Tomography (PET) in Head and Neck Malignancies and Intracranial Metastases | NCT05408871 | Cancer Head Nec... Metastatic Canc... Metastatic Lung... | adnectin 18F-BM... adnectin 18F-BM... | 18 Years - | Yale University | |
Stereotactic Radiosurgery (SRS) for Multiple CNS Mets | NCT02567643 | Metastatic Canc... Brain Metastase... | Stereotactic Ra... | - | The Cooper Health System | |
Doxil, Bevacizumab and Temsirolimus Trial | NCT00761644 | Advanced Cancer | Doxil Bevacizumab Temsirolimus | 12 Years - | M.D. Anderson Cancer Center | |
A Phase 2 Trial for Patients With Metastatic Solid Cancer | NCT04713371 | Metastatic Canc... | Keytruda Inject... Yervoy Injectab... Cytoxan Cryosurgical fr... GM-CSF Injectab... | 18 Years - | Rampart Health, L.L.C. | |
Doxil, Bevacizumab and Temsirolimus Trial | NCT00761644 | Advanced Cancer | Doxil Bevacizumab Temsirolimus | 12 Years - | M.D. Anderson Cancer Center | |
Paclitaxel and Hyperthermic Perfusion in Treating Patients With Lung Cancer or Lung Metastases That Cannot Be Removed By Surgery | NCT00020007 | Lung Cancer Metastatic Canc... | isolated perfus... paclitaxel hyperthermia tr... | 18 Years - | National Cancer Institute (NCI) | |
Matrix Metalloproteinases After Surgery and/or Radiofrequency Ablation in Patients With Liver Metastases From Colorectal Cancer | NCT00899210 | Colorectal Canc... Metastatic Canc... | laboratory biom... cryosurgery radiofrequency ... therapeutic con... | 18 Years - | National Cancer Institute (NCI) | |
Photodynamic Therapy With Porfimer Sodium in Treating Patients With Refractory Brain Tumors | NCT00002647 | Brain and Centr... Metastatic Canc... | verteporfin conventional su... | 3 Years - 70 Years | National Cancer Institute (NCI) | |
FOLFIRI Alternate With FOLFOX in Untreated Metastatic Gastric and Esophageal Adenocarcinoma | NCT03528876 | Metastatic Gast... | FOLFOX and FOLF... | 18 Years - | University of Saskatchewan | |
Study of Avutometinib (VS-6766) + Adagrasib in KRAS G12C NSCLC Patients | NCT05375994 | Non Small Cell ... KRAS Activating... Advanced Cancer Metastatic Canc... Malignant Neopl... Malignant Neopl... | avutometinib (V... | 18 Years - | Verastem, Inc. | |
Chemotherapy and Bevacizumab With or Without Radiofrequency Ablation in Treating Unresectable Liver Metastases in Patients With Colorectal Cancer | NCT00043004 | Colorectal Canc... Metastatic Canc... | bevacizumab FOLFOX regimen fluorouracil leucovorin calc... oxaliplatin conventional su... radiofrequency ... | 18 Years - 80 Years | European Organisation for Research and Treatment of Cancer - EORTC | |
Modified Tumor Infiltrating Lymphocytes for Metastatic Melanoma | NCT01369875 | Metastatic Mela... Skin Cancer | Cyclophosphamid... Fludarabine Aldesleukin Tumor Infiltrat... | 18 Years - | National Institutes of Health Clinical Center (CC) | |
Metastatic Pathologic Fractures, Short Term Results | NCT05825456 | Pathologic Frac... Bone Metastases Metastatic Canc... | endoprosthetic ... Intramedullary ... Open reduction ... | - | Ankara University | |
Surgery With or Without Combination Chemotherapy in Treating Patients With Lung Metastases From Soft Tissue Sarcoma | NCT00002764 | Endometrial Can... Kidney Cancer Metastatic Canc... Ovarian Cancer Pheochromocytom... Sarcoma | filgrastim doxorubicin hyd... ifosfamide conventional su... | 16 Years - | European Organisation for Research and Treatment of Cancer - EORTC | |
Triage of Advanced Cervical Cancer Through Immunotherapy Induction (TRACTION) | NCT05475171 | Metastatic Canc... Cervical Cancer | MGD019 | 18 Years - | M.D. Anderson Cancer Center | |
Harvesting Cells for Experimental Cancer Treatments | NCT00068003 | Melanoma Gastrointestina... Metastatic Canc... Breast Cancer Non-Small Cell ... | Anti-CD19 CAR P... | 18 Years - | National Institutes of Health Clinical Center (CC) | |
A Study of ART4215 for the Treatment of Advanced or Metastatic Solid Tumors | NCT04991480 | Advanced Cancer Metastatic Canc... Breast Cancer | ART4215 Talazoparib Niraparib | 18 Years - | Artios Pharma Ltd |