Spots Global Cancer Trial Database for A Study of LY3023414 in Participants With Advanced Cancer
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Trial Identification
Brief Title: A Study of LY3023414 in Participants With Advanced Cancer
Official Title: A Phase 1 First-in-Human Dose Study of LY3023414 in Patients With Advanced Cancer
Study ID: NCT01655225
Study Description
Brief Summary: The purpose of this study is to find a recommended dose level and schedule of dosing LY3023414 that can safely be taken by participants with advanced or metastatic cancer. The study will also explore the changes to various markers in blood cells and potentially tumor cells. Finally, the study will help document any antitumor activity this drug may have. In Part A of this study, participants with advanced/metastatic cancer (including lymphoma) will receive increasing doses of LY3023414. In Part B, LY3023414 will be explored in different types of cancer, including breast and lung cancer, lymphoma and mesothelioma.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
UCLA Medical Center, Los Angeles, California, United States
Memorial Sloan Kettering Cancer Center, New York, New York, United States
Peggy and Charles Stephenson Oklahoma Cancer Center, Oklahoma City, Oklahoma, United States
Penn Presbyterian Medical Center, Philadelphia, Pennsylvania, United States
Sarah Cannon Cancer Center, Nashville, Tennessee, United States
Tennessee Oncology PLLC, Nashville, Tennessee, United States
Azienda Ospedaliero - Universitaria S. Luigi Gonzaga, Orbassano, Torino, Italy
Fundacion de Investigacion de Diego, San Juan, , Puerto Rico
Contact Details
Name: Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST)
Affiliation: Eli Lilly and Company
Role: STUDY_DIRECTOR
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