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Spots Global Cancer Trial Database for Phase 2 Study of ABT-869 in Combination With mFOLFOX6 Versus Bevacizumab in Combination With mFOLFOX6 to Treat Advanced Colorectal Cancer

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Trial Identification

Brief Title: Phase 2 Study of ABT-869 in Combination With mFOLFOX6 Versus Bevacizumab in Combination With mFOLFOX6 to Treat Advanced Colorectal Cancer

Official Title: An Open-Label, Randomized Phase 2 Study of ABT-869 in Combination With mFOLFOX6 (Oxaliplatin, 5-Fluorouracil, and Folinic Acid) Versus Bevacizumab in Combination With mFOLFOX6 as Second-line Treatment of Subjects With Advanced Colorectal Cancer

Study ID: NCT00707889

Study Description

Brief Summary: To determine the effect of ABT-869 plus mFOLFOX6 compared to bevacizumab plus mFOLFOX6 on disease progression in advanced colorectal cancer.

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Site Reference ID/Investigator# 11341, Chapel Hill, North Carolina, United States

Site Reference ID/Investigator# 20801, Philadelphia, Pennsylvania, United States

Site Reference ID/Investigator# 8360, Nashville, Tennessee, United States

Site Reference ID/Investigator# 18581, Bedford Park, , Australia

Site Reference ID/Investigator# 23443, Herston, , Australia

Site Reference ID/Investigator# 18023, Bonheiden, , Belgium

Site Reference ID/Investigator# 23646, Brussels, , Belgium

Site Reference ID/Investigator# 18026, Leuven, , Belgium

Site Reference ID/Investigator# 18022, Roeselare, , Belgium

Site Reference ID/Investigator# 26662, Jau, , Brazil

Site Reference ID/Investigator# 24245, Porto Alegre, , Brazil

Site Reference ID/Investigator# 23265, Barrie, , Canada

Site Reference ID/Investigator# 21083, Edmonton, , Canada

Site Reference ID/Investigator# 22465, Ottawa, , Canada

Site Reference ID/Investigator# 22141, Nachod, , Czech Republic

Site Reference ID/Investigator# 22289, Heraklion, , Greece

Site Reference ID/Investigator# 22286, Thessaloniki, , Greece

Site Reference ID/Investigator# 22287, Thessaloniki, , Greece

Site Reference ID/Investigator# 18281, Seoul, , Korea, Republic of

Site Reference ID/Investigator# 18283, Seoul, , Korea, Republic of

Site Reference ID/Investigator# 18282, Seoul, , Korea, Republic of

Site Reference ID/Investigator# 20281, Wellington South, , New Zealand

Site Reference ID/Investigator# 20141, Olsztyn, , Poland

Site Reference ID/Investigator# 17946, Warsaw, , Poland

Site Reference ID/Investigator# 38284, Warsaw, , Poland

Site Reference ID/Investigator# 23908, Aveiro, , Portugal

Site Reference ID/Investigator# 22324, Coimbra, , Portugal

Site Reference ID/Investigator# 23724, Faro, , Portugal

Site Reference ID/Investigator# 23964, Lisbon, , Portugal

Site Reference ID/Investigator# 23303, Baia Mare, , Romania

Site Reference ID/Investigator# 23302, Brasov, , Romania

Site Reference ID/Investigator# 17962, Bucharest, , Romania

Site Reference ID/Investigator# 17964, Bucharest, , Romania

Site Reference ID/Investigator# 23304, Bucharest, , Romania

Site Reference ID/Investigator# 17961, Cluj Napoca, , Romania

Site Reference ID/Investigator# 23305, Craiova, , Romania

Site Reference ID/Investigator# 24422, Moscow, , Russian Federation

Site Reference ID/Investigator# 25063, Moscow, , Russian Federation

Site Reference ID/Investigator# 25065, Moscow, , Russian Federation

Site Reference ID/Investigator# 24423, Moscow, , Russian Federation

Site Reference ID/Investigator# 22809, A Coruna, , Spain

Site Reference ID/Investigator# 22807, Barcelona, , Spain

Site Reference ID/Investigator# 22804, Madrid, , Spain

Site Reference ID/Investigator# 22801, Madrid, , Spain

Site Reference ID/Investigator# 22803, Pamplona Navarra, , Spain

Site Reference ID/Investigator# 22800, Santander, , Spain

Contact Details

Name: Mark D. McKee, MD

Affiliation: AbbVie

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

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