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Spots Global Cancer Trial Database for Strategies for Maintenance Therapies in Advanced Non Small Cell Lung Cancer

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Trial Identification

Brief Title: Strategies for Maintenance Therapies in Advanced Non Small Cell Lung Cancer

Official Title: Phase III Study Evaluating Two Strategies of Maintenance, One With Pemetrexed in Continuous Strategy and One According to the Response of Induction Chemotherapy, in Non Squamous Non Small Cell Lung Cancer of Advanced Stage

Study ID: NCT01631136

Study Description

Brief Summary: In France, lung cancer is responsible for more than 30000 each year. Progress was made in treatment of lung cancer in the last five years due to targeted therapies and to strategical evolutions consisting in a best adjustment of treatments. Maintenance strategies is one of this strategical evolution. It is based on maintaining continuous therapeutical pression in order to preserve the therapeutical benefit obtained by the first line (induction chemotherapy). Several clinical trials showed that maintenance strategies increase the duration of controlled disease. There is two types of maintenance strategies: * Continuous maintenance : prolongation of the treatment initially associated with platin until progression * Switch maintenance : introduction of a new treatment after the end of induction chemotherapy The aim of this study is to compare two maintenance strategies * A continuous maintenance by pemetrexed * A switch maintenance or a continuous maintenance according to the response of induction chemotherapy.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Abbeville - CH, Abbeville, , France

Centre Hospitalier du Pays d'Aix, Aix-en-Provence, , France

Clinique Claude Bernard, Albi, , France

Annemasse - CH, Ambilly, , France

Angers - CHU, Angers, , France

Annecy - CH, Annecy, , France

Hôpital Privé d'Antony, Antony, , France

Argenteuil -CH, Argenteuil, , France

Aubenas - CH, Aubenas, , France

CH de la Côte Basque, Bayonne, , France

Beauvais - CH, Beauvais, , France

CHU Besancon - Pneumologie, Besancon, , France

Hôpital Ambroise Paré - Pneumologie, Boulogne, , France

Béziers - CH, Béziers, , France

Caen - Centre François Baclesse, Caen, , France

Caen - CHU Côte de Nacre, Caen, , France

Cahors - CH, Cahors, , France

CH de Cannes, Cannes, , France

Castelnau Le Lez - Clinique, Castelnau, , France

CH Chambery, Chambery, , France

Charleville-Mézières - CH, Charleville-Mézières, , France

Centre Hospitalier, Chauny, , France

CH, Cholet, , France

Hôpital Percy-Armées - Pneumologie, Clamart, , France

CHU, Clermont-Ferrand, , France

Colmar - CH, Colmar, , France

Creil - GHPSO, Creil, , France

CHI Créteil, Créteil, , France

CH de Dax, Dax, , France

Centre d'Oncologie du Parc, Dijon, , France

Centre Georges François Leclerc, Dijon, , France

Draguignan - CH, Draguignan, , France

Grenoble - CHU, Grenoble, , France

Saint Omer - CHI, Helfaut, , France

CH de Jonzac, Jonzac, , France

La Roche Sur Yon - CH, La Roche Sur Yon, , France

Le Mans - Centre Hospitalier, Le Mans, , France

CHU (Hôpital Calmette) - Pneumologie, Lille, , France

Lille - GHPSO, Lille, , France

Limoges - Hôpital du Cluzeau, Limoges, , France

CH de Longjumeau, Longjumeau, , France

Centre Léon Bérard, Lyon, , France

CH Saint Joseph Saint Luc, Lyon, , France

Hôpital de la Croix Rousse, Lyon, , France

Hôpital Louis Pradel, Lyon, , France

Lyon - Hôpital Jean Mermoz, Lyon, , France

CH de Macon, Macon, , France

Hôpital Nord - Oncologie Multidisciplinaire & Innovations Thérapeutiques, Marseille, , France

Maubeuge - Polyclinique du Parc, Maubeuge, , France

Meaux - CH, Meaux, , France

Mont de Marsan - CH, Mont de Marsan, , France

Montpellier - Clinique Clémentville, Montpellier, , France

Centre Hospitalier, Montélimar, , France

Mulhouse - CH, Mulhouse, , France

Nancy - polyclinique Gentilly, Nancy, , France

CHU Nancy, Nancy, , France

Nevers - CH, Nevers, , France

Nice - CAC, Nice, , France

Orléans - CH, Orléans, , France

Paris - Saint Louis, Paris, , France

Hopital Tenon - Pneumologie, Paris, , France

GH Paris Saint-Joseph, Paris, , France

HIA Val-de-Grâce, Paris, , France

Hôpital Bichat - Claude - Bernard, Paris, , France

Paris - Curie, Paris, , France

Pau - CH, Pau, , France

HCL - Lyon Sud (Pneumologie), Pierre Bénite, , France

CHU, Poitiers, , France

Pontoise - CH, Pontoise, , France

Quimper - CH, Quimper, , France

Reims - CHU, Reims, , France

Institut Jean Godinot, Reims, , France

Rennes - CHU, Rennes, , France

Roubaix - CH, Roubaix, , France

Saint Priest en Jarez - ICL, Saint Priest en Jarez, , France

Saint Quentin - CH, Saint Quentin, , France

Saint-Cloud - Centre René Huguenin, Saint-Cloud, , France

Salon de Provence - CH, Salon de Provence, , France

Sens - CH, Sens, , France

Strasbourg - NHC, Strasbourg, , France

Thonon les bains - CH, Thonon les bains, , France

Toulon - CHI, Toulon, , France

Toulon - HIA, Toulon, , France

Toulouse - CHU Larrey, Toulouse, , France

Tourcoing - CH, Tourcoing, , France

Tours - CHU, Tours, , France

Valenciennes - Clinique, Valenciennes, , France

Versailles - CH, Versailles, , France

CHI de la Haute-Saône - Pneumologie, Vesoul, , France

CH de Villefranche - Pneumologie, Villefranche, , France

Centre Hospitalier Intercommunal, Villeneuve-Saint-Georges, , France

Contact Details

Name: Maurice PEROL, MD

Affiliation: Centre Léon Bérard - Lyon

Role: PRINCIPAL_INVESTIGATOR

Name: Pierre-Jean SOUQUET, MD, PhD

Affiliation: Centre Hospitalier Lyon Sud

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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