Spots Global Cancer Trial Database for maintenance
Every month we try and update this database with for maintenance cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Resminostat for Maintenance Treatment of Patients With Advanced Stage Mycosis Fungoides (MF) or Sézary Syndrome (SS) | NCT02953301 | Mycosis Fungoid... Sezary Syndrome Lymphoma, T-Cel... | resminostat Placebo | 18 Years - | 4SC AG | |
| A Study to Compare Iberdomide Maintenance Versus Lenalidomide Maintenance Therapy Following Autologous Stem Cell Transplant in Participants With Newly Diagnosed Multiple Myeloma | NCT05827016 | Multiple Myelom... | Iberdomide Lenalidomide | 18 Years - | Bristol-Myers Squibb | |
| Resminostat for Maintenance Treatment of Patients With Advanced Stage Mycosis Fungoides (MF) or Sézary Syndrome (SS) | NCT02953301 | Mycosis Fungoid... Sezary Syndrome Lymphoma, T-Cel... | resminostat Placebo | 18 Years - | 4SC AG | |
| A Pilot Study of Allopurinol As A Modifier of 6-MP Metabolism in Pediatric ALL | NCT02046694 | Acute Lymphobla... | Allopurinol | - 30 Years | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Maintenance Treatment for Ovarian Carcinoma in Remission by an Antiangiogenic Treatment Strategy | NCT01175772 | Ovarian Carcino... | Cytophosphan, C... | 20 Years - 80 Years | HaEmek Medical Center, Israel | |
| Study of Alpelisib (BYL719) in Combination With Trastuzumab and Pertuzumab as Maintenance Therapy in Patients With HER2-positive Advanced Breast Cancer With a PIK3CA Mutation | NCT04208178 | Advanced HER2+B... | Alpelisib Alpelisib match... Trastuzumab Pertuzumab | 18 Years - | Novartis | |
| Vargatef in Addition to First Line Chemotherapy With Interval Debulking Surgery in Patients With Ovarian Cancer | NCT01583322 | Ovarian Cancer | vargatef placebo | 18 Years - | ARCAGY/ GINECO GROUP | |
| Bevacizumab Plus Capecitabin vs S-1 as Maintenance Treatment Following First-line Chemotherapy in the Patients With Advanced Colorectal Adenocarcinoma | NCT03708536 | Colorectal Aden... | S-1 Bevacizumab Capecitabine | 18 Years - 75 Years | Fujian Cancer Hospital | |
| Study of Sintlimab Maintenance Therapy in Patients With Extensive Small Cell Lung Cancer | NCT03983759 | Small Cell Lung... Extensive Disea... Adoptive Cellul... Chemotherapy Maintenance | sintilimab main... | 18 Years - 70 Years | Henan Cancer Hospital | |
| Rituximab Maintenance Therapy in Aggressive CD20 (Cluster of Differentiation Antigen 20) Positive Lymphoma and Mantle Cell Lymphoma | NCT01933711 | CD20+ Aggressiv... | rituximab | 18 Years - | University Hospital Heidelberg | |
| Phase 3 Study of Teclistamab in Combination With Lenalidomide and Teclistamab Alone Versus Lenalidomide Alone in Participants With Newly Diagnosed Multiple Myeloma as Maintenance Therapy Following Autologous Stem Cell Transplantation | NCT05243797 | Multiple Myelom... | Teclistamab Lenalidomide | 18 Years - | Stichting European Myeloma Network | |
| Strategies for Maintenance Therapies in Advanced Non Small Cell Lung Cancer | NCT01631136 | Advanced Non Sm... | Cisplatin Pemetrexed Cisplatin Gemcitabine | 18 Years - 70 Years | Intergroupe Francophone de Cancerologie Thoracique | |
| Bendamustine and Rituximab (BR) as Induction and Maintenance in Relapsed and Refractory Chronic Lymphocytic Leukemia | NCT03847727 | Chronic Lymphoc... | BR as Maintenan... | 18 Years - | Pirogov Russian National Research Medical University | |
| 3 Anthracyclines, 2 Types of Consolidation With Different ARA-C Doses and Maintenance in Adult Acute Myeloid Leukemia | NCT01587430 | Acute Myeloid L... | high dose ARA-C standard dose A... | 15 Years - 60 Years | National Research Center for Hematology, Russia | |
| Camrelizumab Plus Apatinib as Maintenance Therapy in Extensive-stage Small-cell Lung Cancer | NCT04901754 | Small Cell Lung... | Camrelizumab Pl... | 18 Years - 75 Years | Henan Cancer Hospital | |
| Phase II Study of 5-azacytidine Maintenance After Transplant for AML or MDS | NCT02204020 | Acute Myeloid L... Myelodysplastic... | 5-azacytidine (... | 18 Years - | University of Pittsburgh | |
| Efficacy of COVID-19 Vaccination in Patientstreated With Anti-CD20 for Follicular Lymphoma or Mantle Cell Lymphoma | NCT04918940 | Follicular Lymp... Mantle Cell Lym... | Determination o... | 18 Years - | Centre Henri Becquerel | |
| 3 Anthracyclines, 2 Types of Consolidation With Different ARA-C Doses and Maintenance in Adult Acute Myeloid Leukemia | NCT01587430 | Acute Myeloid L... | high dose ARA-C standard dose A... | 15 Years - 60 Years | National Research Center for Hematology, Russia | |
| Single Autologous Stem Cell Transplantation Followed by Maintenance Therapy as Front-line Treatment for Myeloma | NCT00892346 | Multiple Myelom... | Single ASCT wit... | 18 Years - 65 Years | Shanghai Jiao Tong University School of Medicine | |
| Bortezomib and Dexamethasone as Treatment and Maintenance for Multiple Myeloma Relapse | NCT00335348 | Multiple Myelom... | Bortezomib Dexamethasone | 18 Years - 80 Years | Peter MacCallum Cancer Centre, Australia | |
| ZAR2007: R-CHOP in Folicular Lymphoma Patients no Treated Previously. Consolidation With 90Y Ibritumomab Tiuxetan (Zevalin®) Versus Maintenance Treatment With Rituximab (MabThera®) | NCT00662948 | Lymphoma | Rituximab Ibritumomab tiu... | 18 Years - 75 Years | PETHEMA Foundation | |
| PARP Inhibitor Oral Maintenance in Low-Risk Ovarian Cancer | NCT05187208 | Epithelial Ovar... Ovarian Cancer Ovarian Cancer ... Ovarian Cancer ... | Niraparib | 20 Years - | Seoul National University Hospital | |
| Prospective Biological Study to Evaluate the Persistence of COVID-19 Vaccine and Other Vaccines'-Induced Immune Responses in Follicular Lymphoma Patients Undergoing Frontline Induction Immuno-chemotherapy and Anti-CD20 Maintenance | NCT06070961 | Follicular Lymp... | Cellular immuni... Humoral immunit... Cellular immuni... Humoral immunit... Diphtheria toxi... Tetanus toxoid-... T-cell populati... | 18 Years - | Fondazione Italiana Linfomi - ETS | |
| Maintenance Treatment for Ovarian Carcinoma in Remission by an Antiangiogenic Treatment Strategy | NCT01175772 | Ovarian Carcino... | Cytophosphan, C... | 20 Years - 80 Years | HaEmek Medical Center, Israel | |
| Upifitamab Rilsodotin Maintenance in Platinum-Sensitive Recurrent Ovarian Cancer (UP-NEXT) | NCT05329545 | High Grade Sero... Fallopian Tube ... Primary Periton... | Upifitimab rils... Placebo | 18 Years - | Mersana Therapeutics | |
| Nintedanib as Switch Maintenance Treatment of Pleural Malignant Mesothelioma | NCT02863055 | Malignant Pleur... | Nintedanib Placebo | 18 Years - 90 Years | European Organisation for Research and Treatment of Cancer - EORTC | |
| Maintenance Treatment With S-1 in Gastric Cancer Patients | NCT03701373 | Gastric Cancer ... Cancer of Stoma... | S-1 maintenance Observation | 18 Years - 80 Years | Sun Yat-sen University | |
| Treatment After Irinotecan-based Frontline Therapy: Maintenance With Erbitux (in Patients wtRAS mCRC) | NCT02404935 | Metastatic Colo... | Cetuximab FOLFIRI and cet... | 18 Years - | UNICANCER | |
| Maintenance Avelumab Immunotherapy in Patients With Locally Advanced or Metastatic Squamous Cell Penile Carcinoma | NCT03774901 | Penile Cancer Penile Neoplasm... Penile Squamous... | Avelumab | 18 Years - | Centre Hospitalier Universitaire de Besancon | |
| Primary Rituximab and Maintenance | NCT00140582 | Follicular Lymp... | Rituximab | 18 Years - | Lymphoma Study Association | |
| Pethema Multiple Myeloma 2000 | NCT00560053 | Multiple Myelom... | Alternating che... Autologous Tran... Maintenance Second transpla... ALOGENIC MINI T... | - 69 Years | PETHEMA Foundation | |
| Bortezomib Based Consolidation in Multiple Myeloma Patients Completing Stem Cell Transplant | NCT01706666 | Stage I Multipl... Stage II Multip... Stage III Multi... | bortezomib cyclophosphamid... lenalidomide laboratory biom... dexamethasone quality-of-life... | 18 Years - | Mayo Clinic | |
| Efficacy and Safety of Ofatumumab Retreatment and Maintenance Treatment in Patients With B-cell Chronic Lymphocytic Leukemia (CLL) | NCT00802737 | Leukaemia, Lymp... | Ofatumumab | 18 Years - | GlaxoSmithKline | |
| Bendamustine and Rituximab (BR) as Induction and Maintenance in Relapsed and Refractory Chronic Lymphocytic Leukemia | NCT03847727 | Chronic Lymphoc... | BR as Maintenan... | 18 Years - | Pirogov Russian National Research Medical University | |
| Niraparib With beVAcizumab After Complete cytoreductioN in Patients With ovArian Cancer | NCT05183984 | Ovarian Cancer | Chemotherapy Bevacizumab-Aww... Niraparib | 18 Years - 99 Years | ARCAGY/ GINECO GROUP | |
| Maintenance Avelumab Immunotherapy in Patients With Locally Advanced or Metastatic Squamous Cell Penile Carcinoma | NCT03774901 | Penile Cancer Penile Neoplasm... Penile Squamous... | Avelumab | 18 Years - | Centre Hospitalier Universitaire de Besancon | |
| Phase 3 Study of Teclistamab in Combination With Lenalidomide and Teclistamab Alone Versus Lenalidomide Alone in Participants With Newly Diagnosed Multiple Myeloma as Maintenance Therapy Following Autologous Stem Cell Transplantation | NCT05243797 | Multiple Myelom... | Teclistamab Lenalidomide | 18 Years - | Stichting European Myeloma Network | |
| Thalidomide Maintenance Treatment in DLBCL | NCT03016000 | Lymphoma, Large... | Thalidomide Observation | 18 Years - 60 Years | Nanfang Hospital, Southern Medical University | |
| Camrelizumab Plus Apatinib as Maintenance Therapy in Extensive-stage Small-cell Lung Cancer | NCT04901754 | Small Cell Lung... | Camrelizumab Pl... | 18 Years - 75 Years | Henan Cancer Hospital | |
| Phase 2 Multi-center Study of Anti-PD-1 During Lymphopenic State After HDT/ASCT for Multiple Myeloma | NCT02331368 | Multiple Myelom... | Autologous Stem... Melphalan Lenalidomide MK-3475 | 18 Years - 75 Years | University of Michigan Rogel Cancer Center | |
| UARK 89-001 Phase II Study of Intensive "TOTAL THERAPY" For Untreated or Minimally Treated Patients With Multiple Myeloma | NCT00580372 | Multiple Myelom... | VAD High-Dose cyclo... Hemopoietic ste... EDAP Autologous Hemo... Autologous Hemo... Maintenance | 18 Years - | University of Arkansas | |
| Maintenance Avelumab Immunotherapy in Patients With Locally Advanced or Metastatic Squamous Cell Penile Carcinoma | NCT03774901 | Penile Cancer Penile Neoplasm... Penile Squamous... | Avelumab | 18 Years - | Centre Hospitalier Universitaire de Besancon | |
| First-line Treatment of Ewing Tumours With Primary Extrapulmonary Dissemination in Patients From 2 to 50 Years | NCT03011528 | Ewing Sarcoma F... | VDC-IE x2 VDC-IE TEMIRI Consolidation B... Maintenance Local treatment... Local treatment... | 2 Years - 50 Years | Institut Curie | |
| Resminostat for Maintenance Treatment of Patients With Advanced Stage Mycosis Fungoides (MF) or Sézary Syndrome (SS) | NCT02953301 | Mycosis Fungoid... Sezary Syndrome Lymphoma, T-Cel... | resminostat Placebo | 18 Years - | 4SC AG | |
| Quality of Life Comparison in Advanced Non-squamous Non Small Cell Lung Cancer | NCT01303926 | Non-squamous No... | cisplatin pemet... carboplatin pac... | 18 Years - 70 Years | Gruppo Oncologico Italia Meridionale | |
| Combination Rucaparib With Nivolumab in Small Cell Lung Carcinoma | NCT03958045 | Small Cell Lung... | Rucaparib and N... | 18 Years - | University of Kentucky | |
| Thalidomide Plus Dexamethasone as Maintenance Therapy for Multiple Myeloma | NCT01296503 | Multiple Myelom... | Thalidomide plu... Dexamethasone | 18 Years - 70 Years | Grupo de Estudos Multicentricos em Onco-Hematologia | |
| Predictors of Physical Activity Maintenance in Colorectal Cancer Survivors | NCT03781154 | Colorectal Canc... | Group Exercise | 40 Years - | University of Colorado, Denver | |
| Galinpepimut-S Versus Investigator's Choice of Best Available Therapy for Maintenance in AML CR2/CRp2 | NCT04229979 | Acute Myeloid L... | Galinpepimut-S Azacitidine Venetoclax Decitabine Cytarabine Observation GM-CSF Montanide | 18 Years - | Sellas Life Sciences Group | |
| BrUOG L301 With Non-Small Cell Lung Cancer and Bone Metastases | NCT02283749 | Non Small Cell ... | Xofigo | 18 Years - | Brown University | |
| A Multicentre, Randomized Phase III Study of Rituximab as Maintenance Treatment Versus Observation in Patients With Aggressive B-cell Lymphoma: NHL-13 | NCT00400478 | Diffuse Large B... Follicular NHL ... | Rituximab | 18 Years - | Arbeitsgemeinschaft medikamentoese Tumortherapie | |
| UARK 89-001 Phase II Study of Intensive "TOTAL THERAPY" For Untreated or Minimally Treated Patients With Multiple Myeloma | NCT00580372 | Multiple Myelom... | VAD High-Dose cyclo... Hemopoietic ste... EDAP Autologous Hemo... Autologous Hemo... Maintenance | 18 Years - | University of Arkansas | |
| Bortezomib Based Consolidation in Multiple Myeloma Patients Completing Stem Cell Transplant | NCT01706666 | Stage I Multipl... Stage II Multip... Stage III Multi... | bortezomib cyclophosphamid... lenalidomide laboratory biom... dexamethasone quality-of-life... | 18 Years - | Mayo Clinic | |
| Maintenance Treatment With S-1 in Gastric Cancer Patients | NCT03701373 | Gastric Cancer ... Cancer of Stoma... | S-1 maintenance Observation | 18 Years - 80 Years | Sun Yat-sen University | |
| Maintenance Treatment With Capecitabine in Colorectal Cancer Patients | NCT02027363 | Colorectal Neop... Neoplasms Metas... | Capecitabine Observation | 18 Years - 75 Years | Sun Yat-sen University | |
| Efficacy of COVID-19 Vaccination in Patientstreated With Anti-CD20 for Follicular Lymphoma or Mantle Cell Lymphoma | NCT04918940 | Follicular Lymp... Mantle Cell Lym... | Determination o... | 18 Years - | Centre Henri Becquerel | |
| Nintedanib as Switch Maintenance Treatment of Pleural Malignant Mesothelioma | NCT02863055 | Malignant Pleur... | Nintedanib Placebo | 18 Years - 90 Years | European Organisation for Research and Treatment of Cancer - EORTC | |
| Efficacy of COVID-19 Vaccination in Patientstreated With Anti-CD20 for Follicular Lymphoma or Mantle Cell Lymphoma | NCT04918940 | Follicular Lymp... Mantle Cell Lym... | Determination o... | 18 Years - | Centre Henri Becquerel | |
| A Study to Compare Iberdomide Maintenance Versus Lenalidomide Maintenance Therapy Following Autologous Stem Cell Transplant in Participants With Newly Diagnosed Multiple Myeloma | NCT05827016 | Multiple Myelom... | Iberdomide Lenalidomide | 18 Years - | Bristol-Myers Squibb | |
| Study of Lenalidomide Maintenance Versus Placebo in Responding Elderly Patients With DLBCL and Treated With R-CHOP | NCT01122472 | Lymphoma Diffuse Large B... | Lenalidomide Placebo | 60 Years - 80 Years | The Lymphoma Academic Research Organisation | |
| Maintenance Treatment With Capecitabine in Colorectal Cancer Patients | NCT02027363 | Colorectal Neop... Neoplasms Metas... | Capecitabine Observation | 18 Years - 75 Years | Sun Yat-sen University | |
| Study of Lenalidomide Maintenance Versus Placebo in Responding Elderly Patients With DLBCL and Treated With R-CHOP | NCT01122472 | Lymphoma Diffuse Large B... | Lenalidomide Placebo | 60 Years - 80 Years | The Lymphoma Academic Research Organisation | |
| Thalidomide Plus Dexamethasone as Maintenance Therapy for Multiple Myeloma | NCT01296503 | Multiple Myelom... | Thalidomide plu... Dexamethasone | 18 Years - 70 Years | Grupo de Estudos Multicentricos em Onco-Hematologia | |
| Efficacy and Safety of Anlotinib as Maintenance Treatment After First-line Chemotherapy in SCLC | NCT03780283 | Carcinoma Lung Neoplasm Small Cell Lung... | Anlotinib Hydro... | 18 Years - 75 Years | First Hospital of Shijiazhuang City | |
| Strategies for Maintenance Therapies in Advanced Non Small Cell Lung Cancer | NCT01631136 | Advanced Non Sm... | Cisplatin Pemetrexed Cisplatin Gemcitabine | 18 Years - 70 Years | Intergroupe Francophone de Cancerologie Thoracique | |
| Bevacizumab Plus Capecitabin vs S-1 as Maintenance Treatment Following First-line Chemotherapy in the Patients With Advanced Colorectal Adenocarcinoma | NCT03708536 | Colorectal Aden... | S-1 Bevacizumab Capecitabine | 18 Years - 75 Years | Fujian Cancer Hospital | |
| Vargatef in Addition to First Line Chemotherapy With Interval Debulking Surgery in Patients With Ovarian Cancer | NCT01583322 | Ovarian Cancer | vargatef placebo | 18 Years - | ARCAGY/ GINECO GROUP | |
| BrUOG L301 With Non-Small Cell Lung Cancer and Bone Metastases | NCT02283749 | Non Small Cell ... | Xofigo | 18 Years - | Brown University | |
| Study of Sorafenib Maintenance in Patients With ED-SCLC After Response to Induction Chemotherapy | NCT01159327 | Small Cell Lung... | Sorafenib | 18 Months - | National Cancer Center, Korea | |
| Patients With Newly Diagnosed Multiple Myeloma Comparing KTd vs. KRd Induction Therapy and Investigating a K-mono Maintenance Strategy | NCT02891811 | Multiple Myelom... | Carfilzomib Thalidomide Lenalidomide Dexamethasone | 18 Years - | Arbeitsgemeinschaft medikamentoese Tumortherapie | |
| Maintenance Therapy After Thalidomide-Dexamethasone(ThaDD) for Multiple Myeloma(MM) | NCT00633542 | Multiple Myelom... | thalidomide interferon alph... | 18 Years - | Università Politecnica delle Marche | |
| A Trial of Vigil for Participants With Ovarian Cancer | NCT02346747 | Ovarian Cancer Ovarian Neoplas... | Vigil Placebo | 18 Years - | Gradalis, Inc. | |
| Maintenance Treatment With Capecitabine in Colorectal Cancer Patients | NCT02027363 | Colorectal Neop... Neoplasms Metas... | Capecitabine Observation | 18 Years - 75 Years | Sun Yat-sen University | |
| Treatment After Irinotecan-based Frontline Therapy: Maintenance With Erbitux (in Patients wtRAS mCRC) | NCT02404935 | Metastatic Colo... | Cetuximab FOLFIRI and cet... | 18 Years - | UNICANCER | |
| Rituximab Versus Observation as Maintenance Therapy in Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) | NCT01118234 | Chronic Lymphoc... | Rituximab | 18 Years - | Arbeitsgemeinschaft medikamentoese Tumortherapie | |
| Lenalidomide Maintenance in Plasma Cell Myeloma | NCT02538198 | Plasma Cell Mye... | Lenalidomide | 18 Years - | Memorial Sloan Kettering Cancer Center |
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