Spots Global Cancer Trial Database for A Study to Evaluate AB308 in Combination With AB122 in Participants With Advanced Malignancies
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Trial Identification
Brief Title: A Study to Evaluate AB308 in Combination With AB122 in Participants With Advanced Malignancies
Official Title: A Phase 1/1b Study to Evaluate the Safety and Tolerability of AB308 in Combination With AB122 in Participants With Advanced Malignancies
Study ID: NCT04772989
Study Description
Brief Summary: This is a Phase 1/1b, multicenter, open-label, dose-escalation, and dose-expansion study to evaluate the safety, tolerability, pharmacokinetic (PK), pharmacodynamic (PD), and clinical activity of AB308 in combination with zimberelimab (AB122) in participants with advanced malignancies.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
University of California, Los Angeles, Los Angeles, California, United States
Mayo Clinic Jacksonville - PPDS, Jacksonville, Florida, United States
Goshen Health System, Goshen, Indiana, United States
Holden Comprehensive Cancer Center, Iowa City, Iowa, United States
Norton Cancer Institute-Downtown, Louisville, Kentucky, United States
Mayo Clinic - PPDS, Rochester, Minnesota, United States
Columbia University Medical Center, New York, New York, United States
Ohio State University, Columbus, Ohio, United States
University of Oklahoma Peggy and Charles Stephenson Cancer Center, Oklahoma City, Oklahoma, United States
University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States
Tennessee Onocology - Nashville, Nashville, Tennessee, United States
START South Texas Accelerated Research Therapeutics - San Antonio, San Antonio, Texas, United States
START South Texas Accelerated Research Therapeutics - Mountain Region, West Valley City, Utah, United States
Virginia Cancer Specialists, Fairfax, Virginia, United States
University of Wisconsin - Madison, Madison, Wisconsin, United States
Specjalistyczna Praktyka Lekarska Slawomir Mandziuk, Lubin, , Poland
Med-Polonia Sp. z o.o., Poznań, , Poland
Hospital Universitario Vall d'Hebron, Barcelona, , Spain
Clínica Universidad de Navarra - Madrid, Madrid, , Spain
Clínica Universidad de Navarra, Madrid, , Spain
Hospital Universitario 12 de Octubre, Madrid, , Spain
START MADRID_Hospital Universitario HM Sanchinarro - CIOCC, Madrid, , Spain
Contact Details
Name: Medical Director
Affiliation: Arcus Biosciences
Role: STUDY_DIRECTOR
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