Spots Global Cancer Trial Database for esophageal cancer
Every month we try and update this database with for esophageal cancer cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Clinical Efficacy and Safety of Endoscopic Dilatation With Eso-Filp in Benign Esophageal Strictures | NCT05725473 | Esophageal Canc... | Eso-Flip | 18 Years - | Istituto Clinico Humanitas | |
| Liposomal Doxorubicin in Treating Patients With Advanced Stomach Cancer | NCT00004236 | Esophageal Canc... Gastric Cancer | pegylated lipos... | 18 Years - | National Cancer Institute (NCI) | |
| Esophagectomy With or Without Prior Ischemic Gastric Preconditioning | NCT02457299 | Esophageal Canc... | Two Stage Esoph... One Stage Esoph... | 18 Years - | NorthShore University HealthSystem | |
| Anti-Migration System for Anti-reflux Oeso-gastric Stent (ANTIMIG) | NCT05431738 | Stent Migration GastroEsophagea... | Gastroesophagea... | 18 Years - 91 Years | Société Française d'Endoscopie Digestive | |
| Pre-operative Chemo (CPT11, Cisplatin), Radiotherapy, Plus Surgery for Resectable Esophageal Cancer | NCT00160875 | Esophageal Canc... | Irinotecan hydr... Cisplatin | 18 Years - | University Health Network, Toronto | |
| Endoscopic Prevention of Esophageal Cancer at Tenwek Hospital | NCT02146508 | Esophageal Canc... Esophageal Squa... | Endoscopic Muco... Radiofrequency ... | 18 Years - 85 Years | Tenwek Hospital | |
| Randomized Phase II Trial of a PD-1 Inhibitor INCMGA00012 as Consolidation Therapy After Definitive Concurrent Chemoradiotherapy(RHAPSODY) | NCT04494009 | Esophageal Canc... | INCMGA00012 | 19 Years - | Asan Medical Center | |
| Multimodal Monitoring of Radiotherapy Response in Squamous Cell Cancer | NCT02379039 | Squamous Carcin... Head and Neck C... Anal Cancer Lung Cancer Esophageal Canc... Cervix Cancer | 18 Years - | Umeå University | ||
| The Utility of Circulating Tumour Cells and Plasma microRNA in Esophageal Adenocarcinoma | NCT02812680 | Esophageal Canc... | Blood Draw | 18 Years - | University Health Network, Toronto | |
| Phase II Trial of Pembrolizumab With Trastuzumab and Chemotherapy in Advanced HER2 Positive Esophagogastric (EG) Cancer | NCT02954536 | Esophageal Canc... Gastric Cancer | pembrolizumab trastuzumab capecitabine cisplatin Oxaliplatin 5-Fluorouracil | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Trial of Nivolumab and Cetuximab After Chemoradiation in Esophageal Squamous Cell Carcinoma Patients. | NCT04229459 | Esophageal Squa... | Cisplatin 5-FU Radiation thera... Cetuximab Nivolumab | 18 Years - | Rabin Medical Center | |
| Flavopiridol and Paclitaxel in Treating Patients With Locally Advanced or Metastatic Esophageal Cancer That Has Not Responded to Previous Paclitaxel | NCT00006245 | Esophageal Canc... | alvocidib paclitaxel | 18 Years - | National Cancer Institute (NCI) | |
| Study of NGM120 in Subjects With Advanced Solid Tumors, Pancreatic Cancer, and Prostate Cancer Using Combination Therapy | NCT04068896 | Pancreatic Canc... Metastatic Cast... Bladder Cancer Melanoma Non-small Cell ... Colorectal Canc... Gastric Cancer Esophageal Canc... Ovarian Cancer Head Neck Squam... Prostate Cancer | NGM120 NGM120 NGM120 NGM120 NGM120 NGM120 Placebo | 18 Years - | NGM Biopharmaceuticals, Inc | |
| Cetuximab, Paclitaxel, Carboplatin & Radiation for Esoph, Gastroesoph & Gastric Cancer | NCT00439608 | Esophageal Canc... Gastric Cancer | Cetuximab,Pacli... | 18 Years - | Brown University | |
| Low-dose Aspirin Therapy for Esophageal Cancer | NCT02326779 | Esophageal Canc... | Acetylsalicylic... | 18 Years - | Zhejiang University | |
| Is Screening for Esophageal Pathology in Asymptomatic Patients Post-Treatment for Head and Neck Cancer Beneficial? | NCT00583934 | Esophageal Canc... | 18 Years - | University of California, Davis | ||
| Early Detection of Barrett's Esophagus in Participants With Reflux Symptoms in Primary Care | NCT04656392 | Barrett Esophag... Esophageal Canc... | Breath test (eN... | 50 Years - 75 Years | Radboud University Medical Center | |
| Motivational Counseling in Preventing Smoking Relapse After Pregnancy in Pregnant Women Who Quit Smoking During Pregnancy | NCT00310115 | Bladder Cancer Cervical Cancer Esophageal Canc... Gastric Cancer Head and Neck C... Kidney Cancer Leukemia Liver Cancer Lung Cancer Pancreatic Canc... Tobacco Use Dis... | Smoking Prevent... Counseling Inte... Counseling Inte... | 18 Years - | M.D. Anderson Cancer Center | |
| Traditional Three Incisions vs Minimally Invasive Thoracol-laparoscopic Esophagectomy for Esophageal Cancer | NCT02355249 | Esophageal Carc... | MIE OE | 18 Years - 75 Years | ChineseAMS | |
| Celecoxib to Prevent Cancer in Patients With Barrett's Esophagus | NCT00005878 | Esophageal Canc... | celecoxib | 18 Years - 120 Years | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| S-1, Cisplatin, and Radiation Therapy in Treating Patients With Stage IIA, Stage III, or Stage IVA Esophageal Cancer That Can Be Removed by Surgery | NCT00659113 | Esophageal Canc... | cisplatin tegafur-gimerac... cytology specim... endoscopic biop... | 18 Years - 75 Years | National Cancer Institute (NCI) | |
| Nimotuzumab Combined With Radiotherapy for Older Patients With Esophageal Cancer: a Single, Non-control Clinical Trial | NCT01463605 | Esophageal Canc... | Nimotuzumab | 70 Years - | ChineseAMS | |
| S0414 Cetuximab, Combo Chemo, and RT in Locally Advanced Esophageal Cancer | NCT00109850 | Esophageal Canc... | cetuximab cisplatin irinotecan hydr... radiation thera... | 18 Years - | SWOG Cancer Research Network | |
| A Survivorship Care Plan for Gynaecological Cancer Patients | NCT01582906 | Adenocarcinoma ... Cervical Cancer Endometrial Can... Esophageal Canc... Fallopian Tube ... Gastric Cancer Ovarian Cancer Sarcoma Vaginal Cancer Vulvar Cancer | 18 Years - 60 Years | Royal Marsden NHS Foundation Trust | ||
| Docetaxel-polymeric Micelles(PM) and Oxaliplatin for Esophageal Carcinoma | NCT03585673 | Esophagus Squam... Metastatic Canc... | Docetaxel-PM Oxaliplatin | 18 Years - | Dong-A University Hospital | |
| Camrelizumab Combined With CRT for Treatment of Patients With Local Recurrence of Esophageal Cancer | NCT04390945 | Esophageal Canc... | Camrelizumab | 18 Years - 75 Years | The First Affiliated Hospital of Henan University of Science and Technology | |
| Chemoradiation Versus Esophagectomy for Locally Advanced Esophageal Cancer | NCT02972372 | Esophagus Cance... | CRT surgery | 18 Years - 75 Years | The First Affiliated Hospital of Henan University of Science and Technology | |
| Study of Safety & Efficacy of the Combination of LJM716 & BYL719 in Patients With Previously Treated Esophageal Squamous Cell Carcinoma (ESCC) | NCT01822613 | Esophageal Squa... | LJM716 BYL719 Paclitaxel Docetaxel Irinotecan | 18 Years - | Novartis | |
| NIR-Guided Sentinel Lymph-Node Mapping for Esophageal Cancer | NCT01808417 | Esophageal Canc... | Near Infrared I... | 18 Years - | Dana-Farber Cancer Institute | |
| Pembrolizumab Combined With Preoperative Chemotherapy (Albumin Paclitaxel+Carboplatin) Neoadjuvant Therapy for Resectable Locally Advanced (Stage II/III) Esophageal Squamous Cell Carcinoma | NCT06304350 | Esophageal Canc... | Combination of ... | 18 Years - 75 Years | Tongji University | |
| Pain Management Smartphone Application for Patients With Stage III-IV Head and Neck Cancer Undergoing Radiation Therapy | NCT02324881 | Head and Neck C... Pain Lung Cancer Esophageal Canc... | Telephone-Based... Questionnaire A... | 18 Years - | Vanderbilt-Ingram Cancer Center | |
| Thoracic Surgery Combined With Intrathoracic Hyperthermic Perfusion for Advanced Lung Cancer / Esophageal Cancer | NCT03110939 | Esophageal Canc... Lung Cancer Hyperthermic Pe... | hyperthermic pe... | 18 Years - 80 Years | Henan Cancer Hospital | |
| Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Esophageal Cancer | NCT00005638 | Esophageal Canc... Gastric Cancer | cisplatin irinotecan hydr... radiation thera... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Perception Prognosis, Goals of Treatment, and Communication | NCT01401894 | Gastric Cancer Esophageal Canc... Pancreatic Canc... Liver Cancer Biliary Cancer | 18 Years - | Massachusetts General Hospital | ||
| Irinotecan/Cisplatin, Potentially Curative Surgery With or Without Floxuridine, Followed by Capecitabine for Stomach and Gastro-esophageal Junction (GEJ) Cancers | NCT00848783 | Gastric Cancer Gastric Adenoca... Esophageal Canc... | Irinotecan Cisplatin Surgery Floxuridine Capecitabine | 18 Years - | NYU Langone Health | |
| Radiation Therapy and Cardiac Enzymes | NCT00777751 | Tumor | 18 Years - | M.D. Anderson Cancer Center | ||
| Research on the Role of SLC1A5 in the Development of Esophageal Cancer | NCT02633436 | Esophageal Canc... Amino Acid Tran... | SLC1A5 expressi... | 18 Years - | Fourth Affiliated Hospital of Guangxi Medical University | |
| Gefitinib in Treating Patients With Esophageal Cancer That is Progressing After Chemotherapy | NCT01243398 | Adenocarcinoma ... Esophageal Canc... | quality-of-life... | 18 Years - | University of Oxford | |
| Gefitinib in Treating Patients With Stage I, Stage II, or Stage III Esophageal Cancer That Can Be Removed By Surgery | NCT00258297 | Esophageal Canc... | gefitinib conventional su... enzyme inhibito... neoadjuvant the... protein tyrosin... surgery | 18 Years - | University of Rochester | |
| Effect of CCRT on Respiratory Performance and Functional Capacity in Esophagus Cancer Patients | NCT01766349 | Esophageal Canc... | respiratory mus... | 18 Years - 80 Years | Far Eastern Memorial Hospital | |
| Oral Anti-Infective Agent for Esophageal Anastomotic Leakage | NCT00942526 | Anastomotic Lea... | Mycostatin oral... Water | 40 Years - 85 Years | National Taiwan University Hospital | |
| Combination of Cryosurgery and NK Immunotherapy for Advanced Esophageal Cancer | NCT02843581 | Metastatic Esop... | Cryosurgery NK immunotherap... | 30 Years - 70 Years | Fuda Cancer Hospital, Guangzhou | |
| Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors | NCT04354064 | Healthy Volunte... Prostate Cancer Head and Neck C... Esophageal Canc... Genitourinary C... Sarcoma Breast Cancer Colon Cancer Gastrointestina... Solid Tumor Can... Lung Cancer Skin Cancer Melanoma | 18 Years - | Washington University School of Medicine | ||
| Combination Chemotherapy and Radiation Therapy in Treating Patients With Cancer of the Esophagus | NCT00002711 | Esophageal Canc... | chemotherapy cisplatin paclitaxel low-LET electro... low-LET photon ... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Dose Escalated Adaptive RadioTherapy in Definitive Chemo-radiotherapy for Esophageal Cancer | NCT04086901 | Esophageal Canc... | Radiotherapy do... | 18 Years - | University of Aarhus | |
| Antineoplaston Therapy in Treating Patients With Cancer of the Esophagus | NCT00003487 | Adenocarcinoma ... | Antineoplaston ... | 18 Years - 99 Years | Burzynski Research Institute | |
| Lobaplation or Cisplatin in Adjuvant Chemotherapy for Esophageal Carcinoma | NCT03413436 | Esophageal Canc... | Lobaplatin Cisplatin | - | Henan Cancer Hospital | |
| Chemotherapy Plus Radiation Therapy in Treating Patients With Head and Neck Cancer | NCT00002951 | Esophageal Canc... Head and Neck C... | fluorouracil hydroxyurea surgical proced... radiation thera... | - | University of Chicago | |
| Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC | NCT04140526 | Non Small Cell ... Advanced Solid ... Metastatic Mela... Metastatic Head... Metastatic Rena... Metastatic Colo... Sarcomas Metastatic Pros... Ovarian Cancer Small Cell Lung... Metastatic Brea... Pancreas Cancer Gastric Cancer Esophageal Canc... Gastroesophagea... Cervical Cancer Adenoid Cystic ... Salivary Gland ... Urothelial Carc... | ONC-392 Pembrolizumab Docetaxel | 18 Years - | OncoC4, Inc. | |
| ADP-A2M4CD8 in HLA-A2+ Subjects With MAGE-A4 Positive Esophageal or Esophagogastric Junction Cancers (SURPASS-2) | NCT04752358 | Esophageal Canc... Esophagogastric... | Autologous gene... | 18 Years - 75 Years | Adaptimmune | |
| Radiotherapy Combined With Immunochemotherapy in Metastatic Esophageal Squamous Cell Carcinoma | NCT05978193 | Esophageal Squa... Esophageal Canc... Metastatic Esop... | LDRT+CFRT Immunotherapy Chemotherapy | 18 Years - | Shanghai Chest Hospital | |
| TRAstuzumab and Pertuzumab for HER2+ Resectable Oesophageal Cancer | NCT05188313 | Esophageal Canc... Esophageal Aden... | Trastuzumab Pertuzumab Paclitaxel Carboplatin | 18 Years - | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | |
| Evaluations of Alcohol Warning Labels | NCT06129487 | Oral Cancer Esophageal Canc... Larynx Cancer Alcohol Drinkin... | Narrative picto... Non-narrative p... | 21 Years - | University of Connecticut | |
| RESECTED LYMPH NODES AND SURVIVAL OF PATIENTS WITH ESOPHAGEAL SQUAMOUS CELL CARCINOMA: AN OBSERVATIONAL STUDY | NCT05570487 | the Records of ... | Since the data ... | 18 Years - 90 Years | Sichuan Cancer Hospital and Research Institute | |
| A Study to Evaluate LBL-007 in Combination With Tislelizumab Plus Chemotherapy in Participants With Unresectable Locally Advanced or Metastatic Esophageal Squamous Cell Carcinoma | NCT06010303 | Esophageal Canc... Esophageal Squa... Esophageal Squa... | LBL-007 Tislelizumab Chemotherapy Do... | 18 Years - | BeiGene | |
| Assessing Timing of Enteral Feeding Support in Esophageal Cancer Patients on Muscle functTion and Survival | NCT03676478 | Esophageal Canc... Nutrition Aspec... Postoperative C... Muscle Weakness Sarcopenia Jejunostomy; Co... | delayed start e... | 18 Years - 90 Years | University Hospital, Gasthuisberg | |
| Proton Beam Therapy (PBT) Versus Intensity-Modulated Radiation Therapy (IMRT) Trial | NCT01512589 | Esophageal Canc... | Proton Beam The... Intensity Modul... Questionnaires | 18 Years - | M.D. Anderson Cancer Center | |
| Endoscopic Ultrasound Plus Submucosal Injection for Early Esophageal Cancer | NCT01555801 | Esophageal Canc... | submucosal inje... ordinary endoso... | 18 Years - 65 Years | Sun Yat-sen University | |
| Safety Study of EMD 72000 in Combination With ECX (Epirubicin, Cisplatin and Capecitabine) in Oesophagogastric Cancer | NCT00113581 | Esophageal Canc... Gastric Cancer | EMD 72000 (matu... | 18 Years - | Merck KGaA, Darmstadt, Germany | |
| Study of Anti-PD-1 Antibody SHR-1210 Plus Apatinib vs SHR-1210 as Second-Line Treatment of Advanced Esophageal Squamous Cell | NCT05049681 | Esophageal Canc... | Camrelizumab Apatinib | 18 Years - 75 Years | The First Affiliated Hospital of Zhengzhou University | |
| DRIHNC - Dehydration Reduction in Head & Neck Cancer | NCT03799380 | Dehydration Head & Neck Can... Esophageal Canc... | Gatorade G2 Standard of car... | 18 Years - | Case Comprehensive Cancer Center | |
| A Study of PRT1419 in Patients With Advanced Solid Tumors | NCT04837677 | Sarcoma Melanoma Lung Cancer Breast Cancer Esophageal Canc... Cervical Cancer Head and Neck C... | PRT1419 | 18 Years - | Prelude Therapeutics | |
| Fully Covered or Partially Covered Stents in Malignant Esophageal Strictures | NCT01661686 | Esophageal Canc... Esophageal Sten... | Partially cover... Fully covered S... | 18 Years - | Foundation for Liver Research | |
| Quality of Life Assessment of Patients Receiving Treatment for Esophageal Cancer [Companion to CALGB-9781] | NCT00003381 | Esophageal Canc... | 18 Years - | Alliance for Clinical Trials in Oncology | ||
| Efficacy of Nasogastric Tube Application in Postoperative Care of Esophagectomy | NCT03273686 | Esophageal Canc... | Discharge the N... | 18 Years - 80 Years | Fudan University | |
| Preoperative Inspiratory Muscle Training in Esophageal Resection | NCT01893008 | Esophageal Rese... | Inspiratory Mus... | 18 Years - | UMC Utrecht | |
| The PET-CT Predicting Response to Immunochemotherapy in Esophageal Cancer | NCT05615103 | Esophageal Canc... | 18 Years - 78 Years | Guangdong Provincial People's Hospital | ||
| Chemotherapy, Radiation Therapy, and Cetuximab Followed by Surgery, Docetaxel, and Cetuximab in Treating Patients With Esophageal Cancer or Gastroesophageal Junction Cancer | NCT00551759 | Esophageal Canc... | 5-Fluorouracil Oxaliplatin Cetuximab Docetaxel Surgery Radiotherapy | 18 Years - | Eastern Cooperative Oncology Group | |
| Adjuvant Chemotherapy With Paclitaxel and Cisplatin in Lymph Node-Positive Adjuvant Chemotherapy in the Treatment of the Lymph Node Positive Thoracic Esophageal Squamous Cell Carcinoma | NCT02461043 | Esophageal Canc... | paclitaxel; cis... radiation | 18 Years - | ChineseAMS | |
| Clinical Study on the Efficacy of Single-port Inflatable Mediastinoscopy Combined With Laparoscopic-assisted Small Incision Surgery and Thoracoscopy Combined With Laparoscopic Surgery for Radical Esophagectomy | NCT05105945 | Esophageal Canc... | Single-Port Inf... Thoracoscopy Co... | 18 Years - 75 Years | Fifth Affiliated Hospital, Sun Yat-Sen University | |
| Tethered Capsule Endoscope in Screening Participants for Barrett Esophagus | NCT00903136 | Esophageal Canc... Precancerous Co... | questionnaire a... comparison of s... diagnostic endo... esophagogastrod... tethered capsul... | 18 Years - 80 Years | National Cancer Institute (NCI) | |
| Sunitinib, Irinotecan, Fluorouracil, and Leucovorin In Treating Patients With Advanced Stomach Cancer or Gastroesophageal Cancer | NCT00524186 | Esophageal Canc... Gastric Cancer | fluorouracil irinotecan hydr... leucovorin calc... sunitinib malat... flow cytometry pharmacological... | - 120 Years | Roswell Park Cancer Institute | |
| CEA Targeting Chimeric Antigen Receptor T Lymphocytes (CAR-T) in the Treatment of CEA Positive Advanced Solid Tumors | NCT06006390 | Gastric Cancer Colon Cancer Rectal Cancer Esophageal Canc... Pancreas Cancer Lung Cancer Breast Cancer | CEA-targeted CA... CEA-targeted CA... | 18 Years - | Chongqing Precision Biotech Co., Ltd | |
| Combination of Targeted and Immunotherapy for Advanced Biliary Tract and Esophagogastric Gastric Cancer | NCT03818997 | Esophageal Canc... Biliary Tract C... GastroEsophagea... Hepatobiliary N... | DKN-01 Atezolizumab Paclitaxel | 18 Years - | European Organisation for Research and Treatment of Cancer - EORTC | |
| S-1 Concurrent With Radiotherapy Versus Radiotherapy for Elderly Patients With Esophageal Cancer | NCT02813967 | Esophageal Canc... Chemoradiation | Radiotherapy 54... Radiotherapy 60... S-1 | 70 Years - 85 Years | Zhejiang Cancer Hospital | |
| Prehabilitation and Rehabilitation for Patients With Oesophageal Cancer | NCT04894149 | Esophageal Canc... | Physiotherapy | 18 Years - | Karolinska University Hospital | |
| Safety of AMG 706 Plus Panitumumab Plus Gemcitabine-Cisplatin in the Treatment of Patients With Advanced Cancer | NCT00101907 | Lung Cancer Pancreatic Canc... Esophageal Canc... | AMG 706 Panitumumab Gemcitabine Cisplatin | 18 Years - | Amgen | |
| Oesophagectomy and Chest Wall and Respiratory Function | NCT03835273 | Esophageal Canc... Esophagectomy Respiratory Fun... | 3D motion captu... Incentive spiro... Questionnaires | 18 Years - 90 Years | Imperial College London | |
| A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7502175 as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors | NCT05581004 | Locally Advance... NSCLC HNSCC Melanoma TNBC Esophageal Canc... Gastric Cancer Cervical Cancer Urothelial Carc... Clear Cell RCC HCC | RO7502175 Atezolizumab | 18 Years - | Genentech, Inc. | |
| Cetuximab, Docetaxel, Cisplatin, and Radiation Therapy in Treating Patients With Locally Advanced Esophageal Cancer That Can Be Removed by Surgery | NCT00445861 | Esophageal Canc... | cetuximab + doc... Treatment level... Treatment level... conventional su... | 18 Years - 70 Years | Swiss Group for Clinical Cancer Research |
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