Spots Global Cancer Trial Database for A Study Evaluating the Safety, Pharmacokinetics (PK), and Preliminary Efficacy of ABBV-399 in Participants With Advanced Solid Tumors
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
Trial Identification
Brief Title: A Study Evaluating the Safety, Pharmacokinetics (PK), and Preliminary Efficacy of ABBV-399 in Participants With Advanced Solid Tumors
Official Title: A Multicenter, Phase 1/1b, Open-Label, Dose-Escalation Study of ABBV-399, an Antibody Drug Conjugate, in Subjects With Advanced Solid Tumors
Study ID: NCT02099058
Conditions
Study Description
Brief Summary: This is a Phase 1/1b open-label study evaluating the safety, pharmacokinetics (PK), and preliminary efficacy of ABBV-399 as monotherapy and in combination with osimertinib, erlotinib, and nivolumab in participants with advanced solid tumors likely to express c-Met. Enrollment is closed for the monotherapy arms, Arm A, and Arm D.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Scottsdale Healthcare /ID# 123761, Scottsdale, Arizona, United States
City of Hope /ID# 153759, Duarte, California, United States
University of California, Los Angeles /ID# 148295, Los Angeles, California, United States
UC Irvine /ID# 165107, Orange, California, United States
University of California, Davis Comprehensive Cancer Center /ID# 129805, Sacramento, California, United States
Univ of Colorado Cancer Center /ID# 123759, Aurora, Colorado, United States
The University of Chicago Medical Center /ID# 136995, Chicago, Illinois, United States
Ingalls Memorial Hosp /ID# 165876, Harvey, Illinois, United States
Massachusetts General Hospital /ID# 129804, Boston, Massachusetts, United States
Dana-Farber Cancer Institute /ID# 168782, Boston, Massachusetts, United States
Henry Ford Health System /ID# 149857, Detroit, Michigan, United States
Herbert Herman Cancer Center /ID# 149858, Lansing, Michigan, United States
Washington University-School of Medicine /ID# 143798, Saint Louis, Missouri, United States
Summit Medical Group-Florham Park /ID# 217651, Florham Park, New Jersey, United States
Montefiore Medical Park at Eastchester /ID# 218445, Bronx, New York, United States
Northwell Health - Monter Cancer Center /ID# 218170, Lake Success, New York, United States
Duke Cancer Center /ID# 123763, Durham, North Carolina, United States
Tennessee Oncology, PLLC /ID# 129802, Nashville, Tennessee, United States
Mary Crowley Cancer Research /ID# 123760, Dallas, Texas, United States
University of Texas MD Anderson Cancer Center /ID# 154648, Houston, Texas, United States
Virginia Cancer Specialists - Fairfax /ID# 165708, Fairfax, Virginia, United States
Universitair Ziekenhuis Antwerpen /ID# 170118, Edegem, Antwerpen, Belgium
Tampere University Hospital /ID# 165065, Tampere, Pirkanmaa, Finland
AP-HM - Hopital de la Timone /ID# 151570, Marseille CEDEX 05, Bouches-du-Rhone, France
Institut Gustave Roussy /ID# 132747, Villejuif Cedex, Val-de-Marne, France
Duplicate_Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" - IRCCS /ID# 164077, Meldola, Emilia-Romagna, Italy
National Cancer Center Hospital East /ID# 217570, Kashiwa-shi, Chiba, Japan
National Cancer Center Hospital /ID# 217571, Chuo-ku, Tokyo, Japan
The Catholic University of Korea, ST. Vincent's Hospital /ID# 233378, Suwon, Gyeonggido, Korea, Republic of
Yonsei University Health System Severance Hospital /ID# 217333, Seoul, Seoul Teugbyeolsi, Korea, Republic of
Asan Medical Center /ID# 217334, Seoul, , Korea, Republic of
Radboud Universitair Medisch Centrum /ID# 246908, Nijmegen, Gelderland, Netherlands
China Medical University Hospital /ID# 217494, Taichung, , Taiwan
National Cheng Kung University Hospital /ID# 167175, Tainan, , Taiwan
National Taiwan University Hospital /ID# 167173, Taipei City, , Taiwan
Taipei Veterans General Hosp /ID# 217392, Taipei, , Taiwan
Contact Details
Name: ABBVIE INC.
Affiliation: AbbVie
Role: STUDY_DIRECTOR
Take Control of Your Skin and Body Changes Today.
Try out Spots for free, set up only takes 2 mins.
Join others from around the world:
