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Spots Global Cancer Trial Database for A Phase I Study of TAS-102 in Patients With Advanced Solid Tumors With Hepatic Impairment

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We do not endorse or review these studies in any way.

Trial Identification

Brief Title: A Phase I Study of TAS-102 in Patients With Advanced Solid Tumors With Hepatic Impairment

Official Title: A Phase 1, Open-label Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of TAS-102 in Patients With Advanced Solid Tumors and Varying Degrees of Hepatic Impairment.

Study ID: NCT02301104

Interventions

TAS-102

Study Description

Brief Summary: Study to evaluate the safety, tolerability, and pharmacokinetics of TAS-102 in patients with advanced solid tumors and varying degrees of hepatic impairment.

Detailed Description: This is a Phase 1, open-label study to evaluate the safety, tolerability, and pharmacokinetics of TAS-102 in patients with advanced solid tumors with varying degrees of hepatic impairment. The study is conducted in 2 parts: the Pharmacokinetic Part (Cycle 1) and the Extension Part (Cycles 2 and beyond). Patients may continue to receive treatment with TAS-102 during the study extension part only after completion of the Pharmacokinetic Part.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Mayo Clinic, Scottsdale, Arizona, United States

Duarte Clinical Site, Duarte, California, United States

Santa Monica Clinical Site, Santa Monica, California, United States

Baltimore Clinical Site, Baltimore, Maryland, United States

Boston Clinical Site, Boston, Massachusetts, United States

Cleveland Clinical Site, Cleveland, Ohio, United States

Pittsburgh Clinical Site, Pittsburgh, Pennsylvania, United States

Dallas Clinical Site, Dallas, Texas, United States

Contact Details

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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