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Brief Title: EsophaCap for the Detection of Early Esophageal Carcinoma
Official Title: EsophaCap for the Detection of Early Esophageal Carcinoma
Study ID: NCT04214119
Brief Summary: This study is to identify potential biomarkers for the early detection of Barrett's Esophagus, esophageal carcinoma (both adenocarcinoma and squamous cell carcinoma), and gastric cancer via sponge cytology.
Detailed Description: This study is to identify potential biomarkers for the early detection of Barrett's Esophagus, esophageal carcinoma (both adenocarcinoma and squamous cell carcinoma). Esophageal and gastric cytology will be collected via sponge capsule. Candidate genes will be tested with DNA isolated from these samples in order to identify optimal biomarkers to differentiate between Barrett's esophagus and esophageal/gastric cancer versus normal esophageal/gastric tissue.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: Yes
Bayview Medical Center, Baltimore, Maryland, United States
Johns Hopkins Hospital, Baltimore, Maryland, United States
Name: Stephen Meltzer, M.D.
Affiliation: Johns Hopkins University
Role: PRINCIPAL_INVESTIGATOR