Spots Global Cancer Trial Database for Skin Cancer and Hyperthermia and Radiotherapy
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Trial Identification
Brief Title: Skin Cancer and Hyperthermia and Radiotherapy
Official Title: Skin Cancer and Hyperthermia and Radiotherapy - SAHARA a Two-arm, Open-label, Randomized Controlled Phase II Trial
Study ID: NCT06384053
Study Description
Brief Summary: The SAHARA trial assesses wether combining ultrahypofractionated accelerated radiotherapy (RT) with hyperthermia is as effective as standard hypofractionated high-dose radiation in treating non-melanoma skin cancer (NMSC).
Detailed Description: The SAHARA Trial is investigating if adding hyperthermia to radiotherapy (RT) can enhance treatment outcomes by making cancer cells more sensitive to radiation, thus requiring lower doses and potentially reducing side effects. The trial compares high-dose RT alone with de-escalated RT plus hyperthermia. The aim is to demonstrate that the combination is non-inferior to standard RT in treating non-melanoma skin cancer (NMSC). The trial is designed for elderly people of 65 years or older.
Eligibility
Minimum Age: 65 Years
Eligible Ages: OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Kantonsspital Winterthur, Winterthur, Kanton Zuerich, Switzerland
Luzerner Kantonsspital, Luzern, , Switzerland
Contact Details
Name: Maximilian Sturz, MD
Affiliation: Luzerner Kantonsspital
Role: PRINCIPAL_INVESTIGATOR
Name: Arnold Winfried, MD
Affiliation: Luzerner Kantonsspital
Role: PRINCIPAL_INVESTIGATOR
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