Spots Global Cancer Trial Database for hyperthermia
Every month we try and update this database with for hyperthermia cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Preoperative Radiochemotherapy With Hyperthermia for Locally Advanced Rectal Cancer | NCT02353858 | Rectal Cancer Locally Advance... Hyperthermia Hyperthermic Ra... Hyperthermic Ch... Deep Regional H... | Deep regional h... Radiotherapy Chemotherapy (5... | 18 Years - 80 Years | University Hospital Tuebingen | |
| Efficacy of Chemotherapy Combined With Regional Hypothermia in Advanced Malignant Melanoma Patients With Progressive Soft Tissue Metastases | NCT00264056 | Advanced Metast... Refractory to F... | hyperthermia | 18 Years - 70 Years | Fachklinik Hornheide an der Universität Münster | |
| Optimal Application Dose of Superficial Hyperthermia | NCT00766233 | Tumors | Hyperthermal tr... | 18 Years - | Universitätsmedizin Mannheim | |
| Hyperthermia With Flexible Electrode-typed 2-MHz Device During Radiotherapy for Solid Tumors | NCT05282784 | Solid Tumor | Hyperthermia Radiotherapy | 19 Years - 85 Years | Yonsei Hyperthermia Study Group | |
| Pilot Study of a Double Isolation Perfusion Schedule Using Melphalan Alone for Intransit Melanoma or Unresectable Sarcoma of the Extremity | NCT00001577 | Melanoma Sarcoma | double isolated... | - | National Institutes of Health Clinical Center (CC) | |
| Randomized Study of Combination Chemotherapy With or Without Focused Microwave Thermotherapy Before Surgery in Treating Women With Large Breast Cancer Tumors | NCT01204801 | Breast Cancer | Focused Microwa... Chemotherapy (c... | 18 Years - | Medifocus, Inc. | |
| The Effect of Electro-Hyperthermia in Preoperative Radiotherapy for Locally Advanced Rectal Cancer | NCT02546596 | Rectal Cancer Hyperthermia | Electro-hyperth... | 19 Years - 85 Years | Yonsei Hyperthermia Study Group | |
| Hyperthermia Enhanced Re-irradiation of Loco-regional Recurrent Tumors | NCT04889742 | Recurrent Cance... Prostate Cancer Cervical Cancer Anal Cancer Sarcoma Rectal Cancer Neuroendocrine ... Esophageal Canc... Pancreas Cancer Squamous Cell C... | loco-regional h... | 18 Years - | Charite University, Berlin, Germany | |
| Hyperthermia Combined With Immune Checkpoint Inhibitor Therapy for Advanced Gastrointestinal Tumours | NCT06022692 | Gastrointestina... | Water-filtered ... tislelizumab (B... | 18 Years - 75 Years | Zhejiang Hospital | |
| Video-assisted Hyperthermic Pleural Chemoperfusion vs Talc Pleurodesis for Refractory Malignant Pleural Effusions. | NCT01409551 | Safety of Inter... Efficacy of Int... Cost Effectiven... | VATS hypertherm... Bedside talc sl... | - 75 Years | Theagenio Cancer Hospital | |
| Impact of an Optimised Monitored Anesthesia on the Patients' Recovery After Cytoreduction Surgery Plus HIPEC | NCT04104334 | Hyperthermia Colorectal Neop... Oxaliplatin | Remifentanil in... Remifentanil in... | 18 Years - | Ciusss de L'Est de l'Île de Montréal | |
| Effects of Deep Regional Hyperthermia in Patients With Anal Carcinoma Treated by Standard Radiochemotherapy | NCT02369939 | Anal Carcinoma | Irradiation Mitomycin C 5-Fluorouracil Hyperthermia | 18 Years - | University of Erlangen-Nürnberg Medical School | |
| Hyperthermia Treatment in Conjunction With Mitomycin C Versus Bacillus Calmette-Guérin Immunotherapy (BCG) for Superficial Bladder Cancer | NCT00384891 | Urinary Bladder... Urinary Bladder... Urinary Bladder... Malignant Tumor... Urologic Diseas... Urologic Neopla... Neoplasms Neoplasms by Si... | Synergo + MMC Bacillus Calmet... | 18 Years - | Medical Enterprises Europe B.V. | |
| Salvage Brachytherapy and Hyperthermia for Recurrent H&N-tumours | NCT03238378 | Locally Recurre... | Brachytherapy Hyperthermia | 18 Years - | University of Erlangen-Nürnberg Medical School | |
| Effects of Deep Regional Hyperthermia in Patients With Anal Carcinoma Treated by Standard Radiochemotherapy | NCT02369939 | Anal Carcinoma | Irradiation Mitomycin C 5-Fluorouracil Hyperthermia | 18 Years - | University of Erlangen-Nürnberg Medical School | |
| A Phase 1 Trial of Perfusion Induced Systemic Hyperthermia (PISH) Over Multiple Cycles for Terminal Ovarian Cancer | NCT02093871 | Ovarian Cancer | ThermalCore Hyp... | 18 Years - 69 Years | ThermalCore Inc | |
| The Effect of Electro-Hyperthermia in Preoperative Radiotherapy for Locally Advanced Rectal Cancer | NCT02546596 | Rectal Cancer Hyperthermia | Electro-hyperth... | 19 Years - 85 Years | Yonsei Hyperthermia Study Group | |
| Genomic Medicine Risk Assessment Care for Everyone - Implementation Phase | NCT06278883 | Cardiovascular ... Cancer Liver Diseases Hyperthermia | Disease Risk As... | 18 Years - | Duke University | |
| Pilot Study of IV and IP Chemotherapy Plus Abdominal Hyperthermia for Ovarian Ca | NCT00787488 | Ovarian Cancer | Hyperthermia | 18 Years - 72 Years | Duke University | |
| Celsius TCS Hyperthermia System PMCF Trial | NCT02896049 | Solid Neoplasms | Hyperthermia | 18 Years - 99 Years | Celsius42 GmbH | |
| Infrared Bioeffect System for the Treatment of Cutaneous Warts | NCT03734003 | Cutaneous Warts Human Papilloma... | liquid nitrogen controllable in... | 18 Years - 70 Years | First Hospital of China Medical University | |
| Comparing the Effectiveness of Combined Hyperthermia and External Beam Radiation (EBRT) Versus EBRT Alone in Treating Patients With Painful Bone Metastases | NCT01842048 | All Type of Can... | Hyperthermia External-beam r... | 21 Years - 80 Years | Shin Kong Wu Ho-Su Memorial Hospital | |
| Skin Cancer and Hyperthermia and Radiotherapy | NCT06384053 | Basal Cell Carc... Squamous Cell C... Non-melanoma Sk... | Water-filtered ... Radiotherapy (R... | 65 Years - | Kantonsspital Winterthur KSW | |
| Preoperative Radiochemotherapy With Hyperthermia for Locally Advanced Rectal Cancer | NCT02353858 | Rectal Cancer Locally Advance... Hyperthermia Hyperthermic Ra... Hyperthermic Ch... Deep Regional H... | Deep regional h... Radiotherapy Chemotherapy (5... | 18 Years - 80 Years | University Hospital Tuebingen | |
| Pilot Study of a Catheter-based Ultrasound Hyperthermia System | NCT00911079 | Cervical Cancer Prostate Cancer | Hyperthermia HDR brachythera... | 18 Years - | University of California, San Francisco | |
| Image-guided Targeted Doxorubicin Delivery With Hyperthermia to Optimize Loco-regional Control in Breast Cancer | NCT03749850 | Metastatic Brea... Breast Cancer Breast Neoplasm... Stage IV Breast... Metastatic Canc... Invasive Ductal... Invasive Ductal... Adenocarcinoma ... | LTLD MR-HIFU induced... Cyclophosphamid... | 18 Years - | UMC Utrecht | |
| Hyperthermia Plus Radiation Therapy in Treating Patients With Nonmetastatic Advanced Prostate Cancer | NCT00003045 | Prostate Cancer | Hyperthermia XRT | 18 Years - | Dana-Farber Cancer Institute | |
| Neoadjuvant Chemoradiation With 5-FU(or Capecitabine) and Oxaliplatin Combined With Hyperthermia in Rectal Cancer | NCT01716949 | Rectal Cancer | Radiotherapy Hyperthermia 5-Fluorouracil Capecitabine Oxaliplatin | 18 Years - | University of Erlangen-Nürnberg Medical School | |
| Effects of Deep Regional Hyperthermia in Patients With Anal Carcinoma Treated by Standard Radiochemotherapy | NCT02369939 | Anal Carcinoma | Irradiation Mitomycin C 5-Fluorouracil Hyperthermia | 18 Years - | University of Erlangen-Nürnberg Medical School | |
| Randomized Study of Combination Chemotherapy With or Without Focused Microwave Thermotherapy Before Surgery in Treating Women With Large Breast Cancer Tumors | NCT01204801 | Breast Cancer | Focused Microwa... Chemotherapy (c... | 18 Years - | Medifocus, Inc. | |
| Moderate Whole Body Hyperthermia for Patients Undergoing Re-irradiation for Head and Neck Cancer -Influence on the Tumor Microenvironment | NCT03547388 | Head and Neck N... Recurrence Tumo... | Moderate whole ... | 18 Years - 75 Years | Charite University, Berlin, Germany | |
| Neoadjuvant Chemoradiation With 5-FU(or Capecitabine) and Oxaliplatin Combined With Hyperthermia in Rectal Cancer | NCT01716949 | Rectal Cancer | Radiotherapy Hyperthermia 5-Fluorouracil Capecitabine Oxaliplatin | 18 Years - | University of Erlangen-Nürnberg Medical School | |
| A Phase I Study of Isolated Hepatic Perfusion With Escalating Dose Melphalan Followed by Postoperative Hepatic Arterial Floxuridine and Leucovorin for Metastatic Unresectable Colorectal Cancers of the Liver | NCT00001576 | Colorectal Neop... Liver Neoplasm Neoplasm Metast... | Melphalan Floxuridine Leucovorin | - | National Institutes of Health Clinical Center (CC) | |
| A Phase II Study of Isolated Hepatic Perfusion (IHP) in Patients With Ocular Melanoma | NCT00062933 | Melanoma | Laparotomy | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Hyperthermia Combined With Immune Checkpoint Inhibitor Therapy for Advanced Gastrointestinal Tumours | NCT06022692 | Gastrointestina... | Water-filtered ... tislelizumab (B... | 18 Years - 75 Years | Zhejiang Hospital | |
| Celsius TCS Hyperthermia System PMCF Trial | NCT02896049 | Solid Neoplasms | Hyperthermia | 18 Years - 99 Years | Celsius42 GmbH | |
| Hyperthermia Combined With Neoadjuvant Radiochemotherapy for LARC | NCT05070832 | Hyperthermia Radiotherapy | Deep Hypertherm... | 18 Years - | Peking University Third Hospital | |
| Genomic Medicine Risk Assessment Care for Everyone - Implementation Phase | NCT06278883 | Cardiovascular ... Cancer Liver Diseases Hyperthermia | Disease Risk As... | 18 Years - | Duke University | |
| A Phase I Study of Isolated Hepatic Portal and Arterial Perfusion (IHP) With Escalating Dose Melphalan for Primary or Metastatic Unresectable Cancers of the Liver | NCT00001587 | Liver Neoplasms Neoplasm Metast... | Isolated hepati... Melphalan | - | National Institutes of Health Clinical Center (CC) | |
| Use of Immediate Hyperthermic Intravesical Chemotherapy Following TURBT | NCT03689478 | Bladder Cancer Hyperthermia Chemotherapy Ef... | Hyperthermic in... | 18 Years - | Chinese University of Hong Kong | |
| Immunostimulating Interstitial Laser Thermotherapy in Breast Cancer | NCT03039127 | Breast Neoplasm... | Immunostimulati... | - | Clinical Laserthermia Systems AB | |
| Organ-preservative Therapy of Bladder Cancer With Radiotherapy or Radiochemotherapy Combined With Hyperthermia | NCT05397262 | Bladder Cancer | Hyperthermia Radiotherapy Chemotherapy 5-... Chemotherapy Ci... | 18 Years - | University of Erlangen-Nürnberg Medical School | |
| Local Hyperthermia for the Treatment of Cervical Intraepithelial Neoplasias | NCT03436251 | Cervical Intrae... Human Papilloma... | Local Hyperther... LEEP or cold kn... Local Hyperther... | 18 Years - 65 Years | First Hospital of China Medical University | |
| Hyperthermia European Adjuvant Trial | NCT01077427 | Resected Pancre... | Gemcitabine + C... Gemcitabine + C... | 18 Years - 75 Years | Klinikum der Universitaet Muenchen, Grosshadern | |
| Hyperthermia Combined Brachytherapy in CCU | NCT01474356 | Cervical Cancer | hyperthermia | 18 Years - | Maria Sklodowska-Curie National Research Institute of Oncology | |
| A Phase II Study of Isolated Hepatic Perfusion (IHP) in Patients With Ocular Melanoma | NCT00062933 | Melanoma | Laparotomy | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Optimal Application Dose of Superficial Hyperthermia | NCT00766233 | Tumors | Hyperthermal tr... | 18 Years - | Universitätsmedizin Mannheim | |
| Registry Trial to Evaluate the Safety and Efficacy of Hyperthermia in Locally Advanced Cancers | NCT05099809 | Locally Advance... | Hyperthermia | 18 Years - | Mahatma Gandhi Institute of Medical Sciences | |
| Image-guided Targeted Doxorubicin Delivery With Hyperthermia to Optimize Loco-regional Control in Breast Cancer | NCT03749850 | Metastatic Brea... Breast Cancer Breast Neoplasm... Stage IV Breast... Metastatic Canc... Invasive Ductal... Invasive Ductal... Adenocarcinoma ... | LTLD MR-HIFU induced... Cyclophosphamid... | 18 Years - | UMC Utrecht | |
| Salvage Brachytherapy and Interstitial Hyperthermia for Locally Recurrent Prostate Carcinoma Following Radiation Therapy | NCT03238066 | Prostate Cancer | Brachytherapy Hyperthermia | 18 Years - | University of Erlangen-Nürnberg Medical School | |
| NanoTherm In Adjuvant Therapy of Glioblastoma Multiforme | NCT06271421 | Glioblastoma Mu... | NanoTherm thera... Glioma Resectio... radiotherapy ac... chemotherapy ac... | 18 Years - | Poznan University of Medical Sciences | |
| Effectiveness of the Combined WLI and Hyperthermia for GI Cancer Liver Metastasis | NCT01963117 | Hyperthermia | Combined hypert... | 20 Years - | Samsung Medical Center | |
| Concurrent Hyperthermia and Chemoradiotherapy in LAPC: Phase II Study | NCT02439593 | Cancer Pancreas | Chemoradiothera... Thermochemoradi... | 18 Years - 80 Years | Kantonsspital Aarau | |
| Prospective Hyperthermia Database in Cancer Patients (HT Register) | NCT05993910 | Hyperthermia Cancer | Hyperthermie Re... | - | Charite University, Berlin, Germany |
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