Spots Global Cancer Trial Database for FLASH Radiotherapy for the Treatment of Symptomatic Bone Metastases in the Thorax
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Trial Identification
Brief Title: FLASH Radiotherapy for the Treatment of Symptomatic Bone Metastases in the Thorax
Official Title: FLASH Radiotherapy for the Treatment of Symptomatic Bone Metastases in the Thorax
Study ID: NCT05524064
Conditions
Interventions
Study Description
Brief Summary: The purpose of this study is to assess toxicities of FLASH radiotherapy treatment and pain relief in subjects with painful thoracic bone metastases. FLASH radiotherapy is radiation treatment delivered at ultra-high dose rates compared to conventional radiation treatment.
Detailed Description: This clinical investigation is designed to assess the toxicities of FLASH radiotherapy treatment, as well as pain relief when used to treat bone metastasis(-es) in the thorax. Workflow metrics of FLASH radiotherapy in the thorax in a clinical setting will also be assessed. Patients at least 18 years of age with painful bone metastases located in the thorax will be considered for the study. Eligible subjects will be treated for painful bone metastases in the thorax using a palliative regimen of FLASH radiotherapy and followed post-treatment until subject death or lost to follow-up.
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States
Contact Details
Name: John Breneman, MD
Affiliation: Medical Director Cincinnati Children's/UC Health Proton Therapy Center
Role: PRINCIPAL_INVESTIGATOR
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