Spots Global Cancer Trial Database for bone metastasis
Every month we try and update this database with for bone metastasis cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Chemoradiation for Bone Metastasis | NCT01784393 | Breast Cancer Bone Metastasis Pain | chemoradiation | 18 Years - | Rabin Medical Center | |
| Pilot Study for Palliation of Pain in Bone Metastases by MR-HIFU | NCT01117246 | Secondary Malig... | High Intensity ... | 18 Years - 80 Years | Philips Healthcare | |
| The Combination Therapy With Ra-223 and Enzalutamide | NCT03305224 | Castration-resi... Bone Metastases | Ra-223 in combi... | 20 Years - | Osaka City University | |
| Antalgic Treatment of Painful Bone Metastases by US-guided High Intensity Focused Ultrasound (HIFU) | NCT01765907 | Bone Metastasis | HIFU | 18 Years - | Theraclion | |
| Luteinizing Hormone-releasing Hormone Analogue and Enzalutamide +/- Zoledronic Acid in Prostate Cancer Patients | NCT03336983 | Prostate Cancer Bone Metastases | Zoledronic Acid Enzalutamide | 18 Years - | Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia | |
| The OPTIMAL Study - A Prospective Cohort of Patients With Bone Metastases of the Long Bones | NCT02705157 | Bone Metastasis | Stabilisation o... Radiotherapy of... | 18 Years - | Leiden University Medical Center | |
| Metastatic Pathologic Fractures, Short Term Results | NCT05825456 | Pathologic Frac... Bone Metastases Metastatic Canc... | endoprosthetic ... Intramedullary ... Open reduction ... | - | Ankara University | |
| Duration of Suppression of Bone Turnover Following Treatment With Zoledronic Acid in Men With Metastatic CRPC | NCT01062503 | Metastatic Pros... Bone Metastasis | Zoledronic acid | 18 Years - | University Health Network, Toronto | |
| Effect of Zoledronic Acid in Patients With Prostate Cancer and Bone Metastasis | NCT00237159 | Prostate Cancer... | Zoledronic acid | 18 Years - | Novartis | |
| Evaluation of Sodium Fluoride PET in the Identification of Bone Metastases in Patients Having Undergone a Choline PET for Occult Recurrence of Prostatic Adenocarcinoma | NCT02876991 | Bone Metastasis | Sodium fluoride... | 18 Years - | Central Hospital, Nancy, France | |
| Risk Factors for Skeletal Related Events in Breast Cancer Patients Receiving Bisphosphonates for Bone Metastases | NCT01144481 | Bone Metastases Breast Cancer | - | University Health Network, Toronto | ||
| FLASH Radiotherapy for the Treatment of Symptomatic Bone Metastases in the Thorax | NCT05524064 | Bone Metastases... | FLASH Radiother... | 18 Years - | Varian, a Siemens Healthineers Company | |
| Assessment of Pain and Quality of Life in Breast and Prostate Cancer Patients With Bone Metastases | NCT00434317 | Neoplasm Metast... | Zoledronic acid | 18 Years - | Novartis | |
| Chemoradiation for Bone Metastasis | NCT01784393 | Breast Cancer Bone Metastasis Pain | chemoradiation | 18 Years - | Rabin Medical Center | |
| Pain Management With Pecfent in the Prevention of Pain Induced by Position in Radiotherapy | NCT02426697 | Bone Metastasis | fentanyl transm... Placebo | 18 Years - | Centre Henri Becquerel | |
| A Phase IV Post Approval Clinical Study of ExAblate Treatment of Metastatic Bone Tumors for the Palliation of Pain | NCT01833806 | Bone Metastasis | ExAblate MRgFUS | 18 Years - | InSightec | |
| Efficacy and Tolerability of Zoledronic Acid With Radiotherapy in Pts With Advanced Osteolytic Bone Lesions | NCT00171964 | Pain Neoplasm Metast... Cancer | Zoledronic acid... | 18 Years - | Novartis | |
| F-18 Sodium Fluoride in Prostate Cancer | NCT01240551 | Prostate Neopla... | F-18 NaF | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Feasibility Study of FLASH Radiotherapy for the Treatment of Symptomatic Bone Metastases | NCT04592887 | Bone Metastasis | FLASH Radiother... | 18 Years - | Varian, a Siemens Healthineers Company | |
| Effect of Zoledronic Acid in Patients With Renal Cell Cancer and Bone Metastasis | NCT00172003 | Renal Cell Canc... Neoplasm Metast... | Zoledronic acid | 18 Years - | Novartis | |
| A Phase IV Post Approval Clinical Study of ExAblate Treatment of Metastatic Bone Tumors for the Palliation of Pain | NCT01833806 | Bone Metastasis | ExAblate MRgFUS | 18 Years - | InSightec | |
| Assessment of Pain and Quality of Life in Breast and Prostate Cancer Patients With Bone Metastases | NCT00434317 | Neoplasm Metast... | Zoledronic acid | 18 Years - | Novartis | |
| Study to Evaluate Zoledronic Acid on Quality of Life and Skeletal-related Events as Adjuvant Treatment in Patients With Hormone-naïve Prostate Cancer and Bone Metastasis Who Have Undergone Orchiectomy | NCT00237146 | Prostate Cancer | Zoledronic acid | 18 Years - | Novartis | |
| Radium-223 Dichloride Asian Population Study in the Treatment of CRPC Patients With Bone Metastasis | NCT01810770 | Prostatic Neopl... | Radium-223 dich... | 18 Years - | Bayer | |
| ZANTE: Zometa and Taxotere in Hormone Refractory Prostate Cancer | NCT00415779 | Metastatic Pros... | docetaxel zoledronic acid | 18 Years - | National Cancer Institute, Naples | |
| Primary Pain Palliation in Bone Metastases Treated With Magnetic Resonance-guided Focused Ultrasound | NCT01693770 | Secondary Malig... | MRgFUS | 18 Years - 90 Years | University of Roma La Sapienza | |
| Magnetic Resonance-Guided High Intensity Focused Ultrasound for Palliation of Painful Skeletal Metastases | NCT01309048 | Bone Metastasis | Philips MR-guid... | 18 Years - | Philips Healthcare | |
| Phase I Trial of Fixed Dose STI571 (Imatinib Mesylate) With Escalating Doses of Docetaxel in Patients With Metastatic Androgen-Independent Prostate Cancer | NCT00038194 | Prostate Cancer | imatinib mesyla... docetaxel | - | M.D. Anderson Cancer Center | |
| Magnetic Resonance-Guided High Intensity Focused Ultrasound for Palliation of Painful Skeletal Metastases | NCT01309048 | Bone Metastasis | Philips MR-guid... | 18 Years - | Philips Healthcare | |
| Regional Database for Collecting Clinical-biological and Imaging Data "Secondary Bone Oncology and Bone Localizations of Hematologic Diseases" | NCT05495802 | Bone Metastases | 18 Years - | University Hospital, Lille | ||
| Whole-Body 3D T1-weighted MR Imaging Anatomical Sequences: GE mDixon vs FSE (View) Approaches in Prostate Cancer. | NCT03034070 | Prostate Adenoc... Metastasis | Diagnostic perf... | 18 Years - 99 Years | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | |
| The OPTIMAL Study - A Prospective Cohort of Patients With Bone Metastases of the Long Bones | NCT02705157 | Bone Metastasis | Stabilisation o... Radiotherapy of... | 18 Years - | Leiden University Medical Center | |
| Study of the Utility of the BOMET-QOL Questionnaire Patients With Breast Cancer and Bone Metastasis | NCT03847220 | Breast Carcinom... | BOMET-QoL quest... | 18 Years - | Spanish Breast Cancer Research Group | |
| Primary Pain Palliation in Bone Metastases Treated With Magnetic Resonance-guided Focused Ultrasound | NCT01693770 | Secondary Malig... | MRgFUS | 18 Years - 90 Years | University of Roma La Sapienza | |
| Comparison of NaF PET-CT and Diffusion MRI in the Diagnosis of Bone Metastases (IMMETAOS) | NCT02876731 | Cancer Bone Metastasis | PET-CT MRI | 18 Years - | Institut Jean-Godinot | |
| Pilot Study of PLX3397 in Patients With Advanced Castration-Resistant Prostate Cancer (CRPC) | NCT01499043 | Prostate Cancer | PLX3397 | 18 Years - | Daiichi Sankyo | |
| Study of Denosumab as Adjuvant Treatment for Women With High Risk Early Breast Cancer Receiving Neoadjuvant or Adjuvant Therapy (D-CARE) | NCT01077154 | Breast Cancer | Placebo Denosumab | 18 Years - | Amgen | |
| Efficacy of Radiotherapy in Combination With Zoledronic Acid in Bone Metastasis Patients With Gastrointestinal Tumors | NCT02784652 | Bone Metastasis Gastrointestina... | Zoledronic acid Radiotherapy | 20 Years - | Severance Hospital | |
| An Investigational Drug (CAL) Versus Zoledronic Acid (Zometa®) in Patients With Breast Cancer | NCT00051779 | Breast Neoplasm... Breast Cancer Metastasis | CAL | 18 Years - | Chugai Pharma USA | |
| ZD4054 With Positron Emission Tomography/Magnetic Resonance Imaging (PET/MRI) for Prostate Cancer | NCT01119118 | Prostate Cancer | ZD4054 | 18 Years - | University of Wisconsin, Madison | |
| Bone Pain Score Validation Initiative | NCT02293642 | Bone Metastasis | 18 Years - | iOMEDICO AG | ||
| Pilot Study of PLX3397 in Patients With Advanced Castration-Resistant Prostate Cancer (CRPC) | NCT01499043 | Prostate Cancer | PLX3397 | 18 Years - | Daiichi Sankyo | |
| Effect of Zoledronic Acid on Bone Metabolism in Patients With Bone Metastasis and Prostate or Breast Cancer | NCT00334139 | Prostate Cancer Breast Cancer Bone Metastasis | Zoledronic Acid | 18 Years - | Novartis | |
| Imaging Evaluation of the Therapeutic Response of Breast Cancer Bone Metastasis (EMOS) | NCT02900118 | Breast Cancer | 18 Years - | Centre Oscar Lambret | ||
| Optimization of Radiotherapy in Treatment of Painful Bone Metastasis | NCT00610272 | Pain Bone Metastasis | Radiotherapy Radiotherapy Radiotherapy Radiotherapy | 18 Years - | International Atomic Energy Agency | |
| A Trial of MBC-11 in Patients With CIBD | NCT02673060 | Bone Metastasis | MBC-11 | 18 Years - | Osteros Biomedica Ltd | |
| Zometa and Circulating Vascular Endothelial Growth Factor (VEGF) in Breast Cancer Patients With Bone Metastasis | NCT00524849 | Metastatic Brea... Bone Metastases | Zoledronic acid Zoledronic acid | 18 Years - 75 Years | Fudan University | |
| F-18 Sodium Fluoride in Prostate Cancer | NCT01240551 | Prostate Neopla... | F-18 NaF | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Standardization Research of TCM Syndrome Differentiation and Treatment on Advanced Breast Cancer | NCT02011880 | Breast Cancer Bone Metastasis | Chinese Herbs | 20 Years - 70 Years | Shanghai University of Traditional Chinese Medicine | |
| Using TRAP to Evaluate the Effect of Zometa on Bone Metastasis Due to Lung Cancer | NCT00265200 | Carcinoma, Non-... Carcinoma, Smal... Metastases | zoledronic acid | 18 Years - | University of Louisville | |
| Radium-223 Dichloride Asian Population Study in the Treatment of CRPC Patients With Bone Metastasis | NCT01810770 | Prostatic Neopl... | Radium-223 dich... | 18 Years - | Bayer | |
| Whole-Body 3D T1-weighted MR Imaging Anatomical Sequences: GE mDixon vs FSE (View) Approaches in Prostate Cancer. | NCT03034070 | Prostate Adenoc... Metastasis | Diagnostic perf... | 18 Years - 99 Years | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | |
| Open Label Phase Two Trial of Radium Ra 223 Dichloride With Concurrent Administration of Abiraterone Acetate Plus Prednisone in Symptomatic Castration-Resistant (Hormone-Refractory) Prostate Cancer Subjects With Bone Metastasis | NCT02097303 | Prostate Cancer | Concurrent use ... | 18 Years - | Carolina Research Professionals, LLC | |
| A Study to Collect Data About Analgesia in Patients With Bone Metastasis | NCT02774213 | Bone Metastasis | Questionnaires ... Clinical Pain A... | 18 Years - | Tools4Patient | |
| ZD4054 With Positron Emission Tomography/Magnetic Resonance Imaging (PET/MRI) for Prostate Cancer | NCT01119118 | Prostate Cancer | ZD4054 | 18 Years - | University of Wisconsin, Madison | |
| Standardization Research of TCM Syndrome Differentiation and Treatment on Advanced Breast Cancer | NCT02011880 | Breast Cancer Bone Metastasis | Chinese Herbs | 20 Years - 70 Years | Shanghai University of Traditional Chinese Medicine | |
| Multicenter Study of Magnetic Resonance-guided High Intensity Focused Ultrasound for Pain Palliation of Bone Metastases | NCT01586273 | Bone Metastasis | MR-HIFU treatme... | 18 Years - | Philips Healthcare | |
| Study of Denosumab as Adjuvant Treatment for Women With High Risk Early Breast Cancer Receiving Neoadjuvant or Adjuvant Therapy (D-CARE) | NCT01077154 | Breast Cancer | Placebo Denosumab | 18 Years - | Amgen | |
| Evaluation of Prognostic Factors: From Breast Cancer to Bone Metastases | NCT04167605 | Breast Cancer M... Bone Metastases | Bone metastasis Breast cancer m... | 18 Years - | I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio | |
| Bioequivalence & Food Effect Study in Patients With Solid Tumor or Hematologic Malignancies | NCT02223052 | Hematological N... Non-Hodgkin's L... Hodgkin's Lymph... Lymphoma Multiple Myelom... Acute Myeloid L... Leukemia Myelodysplastic... Neoplasms Melanoma Breast Cancer Metastatic Brea... Non-Small Cell ... Small Cell Lung... Renal Cell Carc... Glioblastoma Mu... Osteosarcoma Sarcoma Thyroid Cancer Genitourinary | CC-486 Vidaza | 18 Years - | Celgene | |
| Cohorts of Docetaxel or Cabazitaxel in Combination With the Potent CYP3A4 Inhibitor, Clarithromycin | NCT03043989 | Prostate Cancer | Docetaxel Cabazitaxel Clarithromycin | 18 Years - | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Study of Sipuleucel-T W/ or W/O Radium-223 in Men With Asymptomatic or Minimally Symptomatic Bone-MCRPC | NCT02463799 | Prostate Cancer | Radium-223 Sipuleucel-T | 18 Years - | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Survey of XGEVA® Presrcibers in Europe to Evaluate Their Knowledge of the Summary of Product Characteristics Pertaining to Osteonecrosis of the Jaw | NCT01998607 | Solid Tumours Bone Metastasis | Physician Surve... | - | Amgen | |
| Safety/Efficacy of Intravenous Zoledronic Acid When Added to Standard Therapies in Patients With Breast Cancer and Metastatic Bone Lesions | NCT00372710 | Breast Cancer W... | Zoledronic acid | 18 Years - | Novartis | |
| ZANTE: Zometa and Taxotere in Hormone Refractory Prostate Cancer | NCT00415779 | Metastatic Pros... | docetaxel zoledronic acid | 18 Years - | National Cancer Institute, Naples | |
| Study on Prolonging Bone Metastasis-Free Survival in Men With Hormone Refractory Prostate Cancer | NCT00286091 | Hormone Refract... | Denosumab Placebo | 18 Years - | Amgen | |
| Zometa and Circulating Vascular Endothelial Growth Factor (VEGF) in Breast Cancer Patients With Bone Metastasis | NCT00524849 | Metastatic Brea... Bone Metastases | Zoledronic acid Zoledronic acid | 18 Years - 75 Years | Fudan University | |
| Open-label Trial on the Effect of I.V. Zoledronic Acid 4 mg on Bone Density in Hormone Sensitive Prostate Cancer Patients With Bone Metastasis | NCT00035997 | Prostate Cancer | Zometa | 18 Years - | Novartis | |
| Denosumab for Breast Cancer With Bone Mets | NCT01952054 | Breast Cancer | Denosumab | 18 Years - | M.D. Anderson Cancer Center | |
| Effect of Zoledronic Acid in Patients With Prostate Cancer and Bone Metastasis | NCT00237159 | Prostate Cancer... | Zoledronic acid | 18 Years - | Novartis | |
| Assessment of the Efficacy, Tolerability and Pharmaco-economic Impact of Zoledronic Acid Treatment in Prostate Cancer With Bone Metastasis | NCT00241111 | Prostate Cancer... | zoledronic acid | 18 Years - | Novartis | |
| Bone Metastasis and Surgery in Breast Cancer | NCT02125630 | Breast Cancer Surgery | Surgery Systemic therap... | 20 Years - 80 Years | Federation of Breast Diseases Societies | |
| Feasibility Study of FLASH Radiotherapy for the Treatment of Symptomatic Bone Metastases | NCT04592887 | Bone Metastasis | FLASH Radiother... | 18 Years - | Varian, a Siemens Healthineers Company | |
| Cohorts of Docetaxel or Cabazitaxel in Combination With the Potent CYP3A4 Inhibitor, Clarithromycin | NCT03043989 | Prostate Cancer | Docetaxel Cabazitaxel Clarithromycin | 18 Years - | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Magnetic Resonance-Guided High Intensity Focused Ultrasound for Palliation of Painful Skeletal Metastases | NCT01309048 | Bone Metastasis | Philips MR-guid... | 18 Years - | Philips Healthcare | |
| Pro-self Pain Management in Norway | NCT00760305 | Cancer Pain | Pro self pain c... | 18 Years - | Oslo University Hospital | |
| Safety/Efficacy of Intravenous Zoledronic Acid When Added to Standard Therapies in Patients With Breast Cancer and Metastatic Bone Lesions | NCT00372710 | Breast Cancer W... | Zoledronic acid | 18 Years - | Novartis | |
| Evaluation of Prognostic Factors: From Breast Cancer to Bone Metastases | NCT04167605 | Breast Cancer M... Bone Metastases | Bone metastasis Breast cancer m... | 18 Years - | I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio | |
| Phase 3 Study on the Efficacy and Safety of Tanezumab in Patients With Cancer Pain Due to Bone Metastasis Who Are Taking Background Opioid Therapy | NCT02609828 | Bone Metastasis Cancer Pain | Tanezumab | 18 Years - | Pfizer |
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