Spots Global Cancer Trial Database for The Application of Personalized Titanium Plate in the Bone Tumors Around the Knee

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Trial Identification

Brief Title: The Application of Personalized Titanium Plate in the Bone Tumors Around the Knee

Official Title: Personalized Titanium Plate Improves Clinical Outcome in Microwave Ablation of Bone Tumors Around the Knee

Study ID: NCT02901782

Conditions

Bone Tumors

Interventions

Personalized titanium plate

Study Description

Brief Summary: Microwave ablation of bone tumors is time-consuming and usually results in postoperative fractures. Hence the investigators designed and fabricated a titanium plate customized to the patient's bone structures for fixation after the removal of tumorous tissue, to improve the clinical outcomes of microwave ablation.

Detailed Description: 3D models of tumor-bearing bone segments were constructed by using computed tomography (CT) and magnetic resonance imaging (MRI). The 3D models were used to design the model of personalized titanium plates. The model of the plates was transferred into a numerical control machine for manufacturing the personalized titanium plates by 3D printing technology. The plates were then surgically implanted for reconstruction assistance following microwave-induced hyperthermia to remove the bone tumor. Implementation parameters and knee function were then evaluated.