Neoplasms

Musculoskeletal Diseases

All Conditions

Bone Neoplasms

Bone Diseases

Ten males and two females with a mean age of 22.8 years were recruited. They all had bone tumor around the knee.

3D models of tumor-bearing bone segments were constructed by using computed tomography (CT) and magnetic resonance imaging (MRI). The 3D models were used to design the model of personalized titanium plates. The model of the plates was transferred into a numerical control machine for manufacturing the personalized titanium plates by 3D printing technology. The plates were then surgically implanted for reconstruction assistance following microwave-induced hyperthermia to remove the bone tumor. Implementation parameters and knee function were then evaluated.

Personalized titanium plate

Yu Zhang, PhD

Microwave ablation of bone tumors is time-consuming and usually results in postoperative fractures. Hence the investigators designed and fabricated a titanium plate customized to the patient's bone structures for fixation after the removal of tumorous tissue, to improve the clinical outcomes of microwave ablation.

The Application of Personalized Titanium Plate in the Bone Tumors Around the Knee

Personalized Titanium Plate Improves Clinical Outcome in Microwave Ablation of Bone Tumors Around the Knee

including flexion/extension, adduction/abduction, internal/external rotation, anteroposterior translation, distal/lateral translation, medial/lateral translation

Medical Center of Assessment, Prevention and Treatment of Bone & Joint Diseases, Guangdong, China

The First Affiliated Hospital of Guangzhou Medical University

Guangzhou General Hospital of Guangzhou Military Command

Principal Investigator, Clinical Professor

Rare Diseases

Osteosarcoma

Patients with MUTARS® modular reconstruction prostheses following primary or secondary knee bone malignancy with minimal follow-up of one year

MUTARS® modular reconstruction prostheses

Christophe Szymanski, MD

The placement of mega knee prosthesis is a necessity after a large tumor resection and oncological. These mega knee prostheses implanted in the context of oncological surgery have been very few evaluated in the literature.

Active knee extension is essential in order to walk properly. The study propose the evaluation of this prosthesis by checking the possibility of locking of the prosthetic joint and thus the possibility of active walking.

A more in-depth, isokinetic analysis at 1 year of follow-up will also be done in an exploratory manner, as the literature has no data on this subject.

Functional Outcomes of Knee Protheses for Malignant Tumours of Bone

Clinical Results, Isokinetic Analysis and Radiologic Outcomes of Knee MUTARS Protheses Replacement for Malignant Tumours of Bone

rate of patients with successful locking will be estimated by the frequency observed Active locking of the operated knee

Functional results of patients with medullary reconstruction prosthesis,joint amplitudes in flexion-extension and in active, passive,

Functional results of patients with medullary reconstruction prosthesis

The MSTS Score may be used as a functional measure for patients with sarcoma involving the upper limb. The score includes 6 measures (pain, function, emotional acceptance, hand position, manual dexterity, lifting ability) each measure with a maximum of 5 points. The maximum overall score is 30 points. The score is designed to be used after the procedure and is therefore only collected post-operatively.

The Oxford Knee Score (OKS) is a Patient Reported Outcome questionnaire that was developed to specifically assess the patient's perspective of outcome following Total Knee Arthroplasty.

Each of the 12 answers are assigned the previously defined number of points. They range from 1 = least difficult to 5 = most difficult. The 12 ratings are then added together to give a total score used to assess the patient.

Functional results of patients with medullary reconstruction prosthesis

The Knee injury and Osteoarthritis Outcome Score (KOOS) is a patient-reported outcome measurement instrument, developed to assess the patient's opinion about their knee and associated problems Functional results of patients with medullary reconstruction prosthesis

International Knee Society score : range 0 to 200, a higher score means a better outcome Functional results of patients with medullary reconstruction prosthesis

Radiological results of patients with medullary reconstruction prosthesis Radiological criterion : Lower limb axis,Blackburn and Peel index for patellar height, Radiological signs of loosening

Muscle recovery of the operated limb compared to the healthy limb

Muscle recovery of the operated limb compared to the healthy limb

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Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
The Application of Personalized Titanium Plate in the Bone Tumors Around the Knee	NCT02901782	Bone Tumors	Personalized ti...	5 Years - 80 Years	Guangzhou General Hospital of Guangzhou Military Command
Functional Outcomes of Knee Protheses for Malignant Tumours of Bone	NCT04650594	Knee Disease Bone Cancer	MUTARS® modular...	18 Years -	University Hospital, Lille

Spots Global Cancer Trial Database for knee

Every month we try and update this database with for knee cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for knee

Every month we try and update this database with for knee cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for knee cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.