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Spots Global Cancer Trial Database for Premedication Simethione Improves Visibility During Bowel Cleansing for Colonoscopy

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Trial Identification

Brief Title: Premedication Simethione Improves Visibility During Bowel Cleansing for Colonoscopy

Official Title:

Study ID: NCT02540239

Study Description

Brief Summary: To evaluate the efficacy, visibility of low volume polyethyleneglycol-simeticone (2-LPEG-S) for colonoscopy.

Detailed Description: In this randomized controlled study, consecutive outpatients scheduled for elective colonoscopy were randomized into two groups. Group A patients (n = 300) used only 2 L PEG before colonoscopy. Patients in group B (n = 300) were additionally advised to simeticone plus 2 L PEG, The overall quality of colonoscopy cleaning was evaluated using the Boston Bowel Preparation Scale by a single endoscopist who was blinded to the intervention. Visibility was blindly assessed for the amount of air bubbles and adenoma detection rate (ADR). Difficulty of procedure, and adverse events were also evaluated.

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: Yes

Locations

Changhai Hospital, Shanghai, Shanghai, China

Contact Details

Name: LI ZHAO SHEN, M.D

Affiliation: Changhai Hospital

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

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