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Brief Title: Premedication Simethione Improves Visibility During Bowel Cleansing for Colonoscopy
Official Title:
Study ID: NCT02540239
Brief Summary: To evaluate the efficacy, visibility of low volume polyethyleneglycol-simeticone (2-LPEG-S) for colonoscopy.
Detailed Description: In this randomized controlled study, consecutive outpatients scheduled for elective colonoscopy were randomized into two groups. Group A patients (n = 300) used only 2 L PEG before colonoscopy. Patients in group B (n = 300) were additionally advised to simeticone plus 2 L PEG, The overall quality of colonoscopy cleaning was evaluated using the Boston Bowel Preparation Scale by a single endoscopist who was blinded to the intervention. Visibility was blindly assessed for the amount of air bubbles and adenoma detection rate (ADR). Difficulty of procedure, and adverse events were also evaluated.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: Yes
Changhai Hospital, Shanghai, Shanghai, China
Name: LI ZHAO SHEN, M.D
Affiliation: Changhai Hospital
Role: PRINCIPAL_INVESTIGATOR