⭐️⭐️⭐️⭐️⭐️ "A total no brainer"

⭐️⭐️⭐️⭐️⭐️ "Love this, so easy."

Spots is the easy way to track your skin, mole and cancer changes.

Spots Global Cancer Trial Database for Radiation Therapy Plus Chemotherapy in Treating Patients With Supratentorial Glioblastoma Multiforme

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Radiation Therapy Plus Chemotherapy in Treating Patients With Supratentorial Glioblastoma Multiforme

Official Title: A PHASE III TRIAL COMPARING THE USE OF RADIOSURGERY FOLLOWED BY CONVENTIONAL RADIOTHERAPY WITH BCNU TO CONVENTIONAL RADIOTHERAPY WITH BCNU FOR SUPRATENTORIAL GLIOBLASTOMA MULTIFORME

Study ID: NCT00002545

Study Description

Brief Summary: RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Chemotherapy uses different ways to stop tumor cells from dividing so they stop growing or die. Combining radiation therapy with chemotherapy may kill more tumor cells. PURPOSE: Randomized phase III trial to study the effectiveness of radiation therapy and carmustine in treating patients who have supratentorial glioblastoma multiforme.

Detailed Description: OBJECTIVES: I. Determine whether the use of radiosurgery (stereotactic external-beam irradiation) prior to conventional radiotherapy with carmustine (BCNU) improves overall survival compared to conventional radiotherapy plus BCNU alone in patients with supratentorial glioblastoma multiforme. II. Determine and compare the frequency and severity of toxicities associated with these regimens. III. Compare the effects of these two regimens on neurologic function and quality of life. OUTLINE: Randomized study. Arm I: Radiotherapy plus Single-Agent Chemotherapy. Tumor irradiation using megavoltage equipment (at least 4 MV photons); plus Carmustine, BCNU, NSC-409962. Arm II: Radiosurgery followed by Radiotherapy plus Single-Agent Chemotherapy. Stereotactic tumor irradiation; followed by tumor irradiation as in Arm I; plus BCNU. PROJECTED ACCRUAL: 200 patients will be entered over approximately 3 years.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Veterans Affairs Medical Center - Birmingham, Birmingham, Alabama, United States

University of Alabama Comprehensive Cancer Center, Birmingham, Alabama, United States

Huntsville Hospital System, Huntsville, Alabama, United States

Urology Associates - Mobile AL, Mobile, Alabama, United States

MBCCOP - University of South Alabama, Mobile, Alabama, United States

Alabama Oncology, LLC, Montgomery, Alabama, United States

Radiation Oncology Associates of West Alabama, Tuscallosa, Alabama, United States

Providence Cancer Therapy Center, Anchorage, Alaska, United States

St. Joseph's Hospital and Medical Center, Phoenix, Arizona, United States

Arizona Cancer Center, Tucson, Arizona, United States

Providence Saint Joseph Medical Center - Burbank, Burbank, California, United States

Mount Diablo Medical Center, Concord, California, United States

California Cancer Center, Fresno, California, United States

Saint Agnes Cancer Center, Fresno, California, United States

Glendale Memorial Hospital and Health Center, Glendale, California, United States

Sutter Health Western Division Cancer Research Group, Greenbrae, California, United States

Loma Linda University Medical Center, Loma Linda, California, United States

Veterans Affairs Medical Center - Long Beach, Long Beach, California, United States

Kaiser Permanente Medical Center - Los Angeles, Los Angeles, California, United States

USC/Norris Comprehensive Cancer Center, Los Angeles, California, United States

Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California, United States

Beckman Research Institute, City of Hope, Los Angeles, California, United States

Veterans Affairs Outpatient Clinic - Martinez, Martinez, California, United States

CCOP - Bay Area Tumor Institute, Oakland, California, United States

Cancer Care Center, Pomona, California, United States

Mercy Medical Center - Redding, Redding, California, United States

Radiation Oncology Center - Sacramento, Sacramento, California, United States

UCSF Cancer Center and Cancer Research Institute, San Francisco, California, United States

O'Connor Hospital, San Jose, California, United States

Santa Cruz Radiation Oncology Medical Group, Inc., Santa Cruz, California, United States

CCOP - Santa Rosa Memorial Hospital, Santa Rosa, California, United States

Stanford University, Stanford, California, United States

David Grant Medical Center, Travis Air Force Base, California, United States

Radiation Oncology Center - Walnut Creek, Walnut Creek, California, United States

Memorial Hospital Cancer Center, Colorado Springs, Colorado, United States

University of Colorado Cancer Center, Denver, Colorado, United States

Bridgeport Hospital, Bridgeport, Connecticut, United States

Whittingham Cancer Center, Norwalk, Connecticut, United States

CCOP - Christiana Care Health Services, Wilmington, Delaware, United States

Walter Reed Army Medical Center, Washington, District of Columbia, United States

Lykes Center for Radiation Therapy, Clearwater, Florida, United States

Halifax Medical Center, Daytona Beach, Florida, United States

Radiation Therapy Associates - Fort Myers, Fort Myers, Florida, United States

University of Florida Health Science Center, Gainesville, Florida, United States

Health First Holmes Regional Medical Center, Melbourne, Florida, United States

CCOP - Mount Sinai Medical Center, Miami Beach, Florida, United States

Sylvester Cancer Center, University of Miami, Miami, Florida, United States

Baptist Hospital of Miami, Miami, Florida, United States

Florida Radiation Oncology Group, Orange Park, Florida, United States

MD Anderson Cancer Center Orlando, Orlando, Florida, United States

Gulf Coast Cancer Treatment Center, Panama City, Florida, United States

West Florida Cancer Institute - Pensacola, Pensacola, Florida, United States

Bayfront Medical Center, Saint Petersburg, Florida, United States

Sarasota Radiation and Medical Oncology Center, Sarasota, Florida, United States

H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States

Emory University Hospital - Atlanta, Atlanta, Georgia, United States

CCOP - Atlanta Regional, Atlanta, Georgia, United States

Medical Center/John B. Amos Community Cancer Center, Columbus, Georgia, United States

InterCommunity Cancer Center at Rome, Rome, Georgia, United States

South Georgia Medical Center, Valdosta, Georgia, United States

Northwest Community Hospital, Arlington Heights, Illinois, United States

Northwestern Memorial Hospital, Chicago, Illinois, United States

University of Chicago Cancer Research Center, Chicago, Illinois, United States

Ingalls Memorial Hospital, Harvey, Illinois, United States

Loyola University Medical Center, Maywood, Illinois, United States

Lutheran General Cancer Care Center, Park Ridge, Illinois, United States

Methodist Medical Center of Illinois, Peoria, Illinois, United States

CCOP - Central Illinois, Springfield, Illinois, United States

CCOP - Carle Cancer Center, Urbana, Illinois, United States

St. John's Medical Center, Anderson, Indiana, United States

Clarion Health Partners Inc., Indianapolis, Indiana, United States

Community Hospitals of Indianapolis - Regional Cancer Center, Indianapolis, Indiana, United States

Ball Memorial Hospital, Muncie, Indiana, United States

Memorial Hospital of South Bend, South Bend, Indiana, United States

St. Joseph's Radiation Oncology Center, South Bend, Indiana, United States

Wendt Regional Cancer Center of Finley Hospital, Dubuque, Iowa, United States

University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States

Medical Center at Bowling Green, Bowling Green, Kentucky, United States

Veterans Affairs Medical Center - Lexington, Lexington, Kentucky, United States

Albert B. Chandler Medical Center, University of Kentucky, Lexington, Kentucky, United States

James Graham Brown Cancer Center, Louisville, Kentucky, United States

Louisville Radiation Oncology, Louisville, Kentucky, United States

Merle M. Mahr Cancer Center, Madisonville, Kentucky, United States

Western Baptist Hospital, Paducah, Kentucky, United States

Mary Bird Perkins Cancer Center, Baton Rouge, Louisiana, United States

Romagosa Radiation Oncology Center, Lafayette, Louisiana, United States

East Jefferson General Hospital, Metairie, Louisiana, United States

MBCCOP - LSU Medical Center, New Orleans, Louisiana, United States

Tulane University School of Medicine, New Orleans, Louisiana, United States

CCOP - Ochsner, New Orleans, Louisiana, United States

Maine Medical Center, Portland, Maine, United States

Anne Arundel Oncology Center, Annapolis, Maryland, United States

Marlene & Stewart Greenebaum Cancer Center, University of Maryland, Baltimore, Maryland, United States

Greater Baltimore Medical Center and Cancer Center, Baltimore, Maryland, United States

Harbor Hospital Center, Baltimore, Maryland, United States

Radiation Oncology Affiliates of Maryland, P.A., Baltimore, Maryland, United States

Johns Hopkins Oncology Center, Baltimore, Maryland, United States

Massachusetts General Hospital Cancer Center, Boston, Massachusetts, United States

Joint Center for Radiation Therapy, Boston, Massachusetts, United States

Cape Cod Hospital, Hyannis, Massachusetts, United States

Veterans Affairs Medical Center - Boston (Jamaica Plain), Jamaica Plain, Massachusetts, United States

Veterans Affairs Medical Center - Ann Arbor, Ann Arbor, Michigan, United States

CCOP - Ann Arbor Regional, Ann Arbor, Michigan, United States

University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, United States

Barbara Ann Karmanos Cancer Institute, Detroit, Michigan, United States

Henry Ford Hospital, Detroit, Michigan, United States

McLaren Regional Cancer Center, Flint, Michigan, United States

Hurley Medical Center, Flint, Michigan, United States

CCOP - Kalamazoo, Kalamazoo, Michigan, United States

Sparrow Regional Cancer Center, Lansing, Michigan, United States

Marquette General Hospital, Marquette, Michigan, United States

MidMichigan Regional Medical Center, Midland, Michigan, United States

St. Mary's Medical Center, Saginaw, Michigan, United States

Mayo Clinic Cancer Center, Rochester, Minnesota, United States

CCOP - Metro-Minnesota, Saint Louis Park, Minnesota, United States

Ellis Fischel Cancer Center - Columbia, Columbia, Missouri, United States

CCOP - Kansas City, Kansas City, Missouri, United States

Veterans Affairs Medical Center - Saint Louis, Saint Louis, Missouri, United States

St. Louis University Health Sciences Center, Saint Louis, Missouri, United States

Mallinckrodt Institute of Radiology, Saint Louis, Missouri, United States

Cancer Research for the Ozarks, Springfield, Missouri, United States

CCOP - Cancer Research for the Ozarks, Springfield, Missouri, United States

CCOP - Montana Cancer Consortium, Billings, Montana, United States

Methodist Cancer Center - Omaha, Omaha, Nebraska, United States

CCOP - Missouri Valley Cancer Consortium, Omaha, Nebraska, United States

CCOP - Southern Nevada Cancer Research Foundation, Las Vegas, Nevada, United States

Norris Cotton Cancer Center, Lebanon, New Hampshire, United States

Elliot Regional Cancer Center, Manchester, New Hampshire, United States

Veterans Affairs Medical Center - East Orange, East Orange, New Jersey, United States

John F. Kennedy Medical Center, Edison, New Jersey, United States

Trinitas Hosptial - Jersey Street Campus, Elizabeth, New Jersey, United States

South Jersey Hospital - Millville, Millville, New Jersey, United States

Fox Chase Cancer Center at Virtua-Memorial Hospital Burlington County, Mount Holly, New Jersey, United States

Newark Beth Israel Medical Center, Newark, New Jersey, United States

Community Medical Center, Toms River, New Jersey, United States

St. Francis Medical Center, Trenton, New Jersey, United States

Saint Joseph Medical Center, Albuquerque, New Mexico, United States

Cancer Center of Albany Medical Center, Albany, New York, United States

Veterans Affairs Medical Center - Albany, Albany, New York, United States

Albert Einstein Comprehensive Cancer Center, Bronx, New York, United States

State University of New York Health Science Center at Brooklyn, Brooklyn, New York, United States

New York Methodist Hospital, Brooklyn, New York, United States

Roswell Park Cancer Institute, Buffalo, New York, United States

Finger Lakes Radiation Oncology, P.C., Clifton Springs, New York, United States

CCOP - North Shore University Hospital, Manhasset, New York, United States

Beth Israel Medical Center, New York, New York, United States

Kaplan Cancer Center, New York, New York, United States

Memorial Sloan-Kettering Cancer Center, New York, New York, United States

Champlain Valley Physicians Hospital Medical Center, Plattsburgh, New York, United States

Vassar Brothers Hospital, Poughkeepsie, New York, United States

Genesee Hospital - Rochester, Rochester, New York, United States

University of Rochester Cancer Center, Rochester, New York, United States

New York Medical College, Valhalla, New York, United States

Lineberger Comprehensive Cancer Center, UNC, Chapel Hill, North Carolina, United States

Northeast Medical Center, Concord, North Carolina, United States

East Carolina University School of Medicine, Greenville, North Carolina, United States

Catawba Memorial Hospital, Hickory, North Carolina, United States

CCOP - Southeast Cancer Control Consortium, Winston-Salem, North Carolina, United States

Comprehensive Cancer Center of Wake Forest University Baptist Medical Center, Winston-Salem, North Carolina, United States

Meritcare Roger Maris Cancer Center, Fargo, North Dakota, United States

UNI-MED Medical Center, Minot, North Dakota, United States

Akron General Medical Center, Akron, Ohio, United States

Akron City Hospital, Akron, Ohio, United States

Christ Hospital, Cincinnati, Ohio, United States

Ireland Cancer Center, Cleveland, Ohio, United States

University Hospitals of Cleveland, Cleveland, Ohio, United States

Cleveland Clinic Cancer Center, Cleveland, Ohio, United States

CCOP - Columbus, Columbus, Ohio, United States

Arthur G. James Cancer Hospital - Ohio State University, Columbus, Ohio, United States

Veterans Affairs Medical Center - Dayton, Dayton, Ohio, United States

CCOP - Dayton, Kettering, Ohio, United States

CCOP - Toledo Community Hospital Oncology Program, Toledo, Ohio, United States

St. John Medical Center, Tulsa, Oklahoma, United States

Samaritan Regional Cancer Center, Corvallis, Oregon, United States

CCOP - Columbia River Program, Portland, Oregon, United States

Lehigh Valley Hospital, Allentown, Pennsylvania, United States

St. Luke's Hospital Regional Cancer Center, Bethlehem, Pennsylvania, United States

Penn State Geisinger Medical Center, Danville, Pennsylvania, United States

Mercy Catholic Medical Center, Mercy Fitzgerald Divison, Darby, Pennsylvania, United States

Delaware County Memorial Hospital, Drexel Hill, Pennsylvania, United States

Penn State Geisinger Cancer Center, Hershey, Pennsylvania, United States

Allegheny University Hospitals- Hahnemann, Philadelphia, Pennsylvania, United States

University of Pennsylvania Cancer Center, Philadelphia, Pennsylvania, United States

Veterans Affairs Medical Center - Philadelphia, Philadelphia, Pennsylvania, United States

Kimmel Cancer Center of Thomas Jefferson University - Philadelphia, Philadelphia, Pennsylvania, United States

Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States

Albert Einstein Cancer Center, Philadelphia, Pennsylvania, United States

University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, United States

Mercy Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States

Western Pennsylvania Hospital, Pittsburgh, Pennsylvania, United States

Reading Hospital and Medical Center, Reading, Pennsylvania, United States

Mercy Hospital Cancer Center - Scranton, Scranton, Pennsylvania, United States

Grand View Hospital, Sellersville, Pennsylvania, United States

Wilkes Barre General Hospital, Wilkes-Barre, Pennsylvania, United States

CCOP - MainLine Health, Wynnewood, Pennsylvania, United States

York Hospital, York, Pennsylvania, United States

Roger Williams Medical Center/BUSM, Providence, Rhode Island, United States

Medical University of South Carolina, Charleston, South Carolina, United States

CCOP - Greenville, Greenville, South Carolina, United States

CCOP - Upstate Carolina, Spartanburg, South Carolina, United States

Jackson-Madison County General Hospital, Jackson, Tennessee, United States

Baptist Regional Cancer Center - Knoxville, Knoxville, Tennessee, United States

CCOP - Baptist Cancer Institute, Memphis, Tennessee, United States

University of Tennessee, Memphis Cancer Center, Memphis, Tennessee, United States

Vanderbilt Cancer Center, Nashville, Tennessee, United States

Harrington Cancer Center, Amarillo, Texas, United States

Julie and Ben Rogers Cancer Institute, Beaumont, Texas, United States

University of Texas Medical Branch, Galveston, Texas, United States

University of Texas - MD Anderson Cancer Center, Houston, Texas, United States

Wilford Hall - 59th Medical Wing, Lackland Air Force Base, Texas, United States

Joe Arrington Cancer Research and Treatment Center, Lubbock, Texas, United States

Bayshore Medical Center, Pasadena, Texas, United States

East Texas Medical Center - Cancer Institute, Tyler, Texas, United States

Dixie Regional Medical Center, Saint George, Utah, United States

LDS Hospital, Salt Lake City, Utah, United States

CCOP - Southwestern Vermont Regional Cancer Center, Bennington, Vermont, United States

Vermont Cancer Center, Burlington, Vermont, United States

Green Mountain Oncology Group, Rutland, Vermont, United States

Veterans Affairs Medical Center - White River Junction, White River Junction, Vermont, United States

Martha Jefferson Hospital, Charlottesville, Virginia, United States

Cancer Center, University of Virginia HSC, Charlottesville, Virginia, United States

Virginia Baptist Hospital, Lynchburg, Virginia, United States

Naval Medical Center, Portsmouth, Portsmouth, Virginia, United States

Massey Cancer Center, Richmond, Virginia, United States

Swedish Cancer Institute, Seattle, Washington, United States

Virginia Mason Medical Center, Seattle, Washington, United States

Deaconess Medical Center, Spokane, Washington, United States

Yakima Valley Memorial Hospital, Yakima, Washington, United States

Schiffler Oncology Center, Wheeling, West Virginia, United States

St. Vincent Hospital, Green Bay, Wisconsin, United States

Gundersen Lutheran Medical Foundation, La Crosse, Wisconsin, United States

Veterans Affairs Medical Center - Madison, Madison, Wisconsin, United States

Southern Wisconsin Radiotherapy Center, Madison, Wisconsin, United States

University of Wisconsin Comprehensive Cancer Center, Madison, Wisconsin, United States

Marshfield Clinic, Marshfield, Wisconsin, United States

Community Memorial Hospital, Menomonee Falls, Wisconsin, United States

St. Joseph's Hospital, Milwaukee, Wisconsin, United States

Columbia Hospital, Milwaukee, Wisconsin, United States

St. Luke's Medical Center, Milwaukee, Wisconsin, United States

Medical College of Wisconsin, Milwaukee, Wisconsin, United States

Veterans Affairs Medical Center - Milwaukee (Zablocki), Milwaukee, Wisconsin, United States

Southeastern Wisconsin Regional Cancer Center, Racine, Wisconsin, United States

Waukesha Memorial Hospital, Waukesha, Wisconsin, United States

Tom Baker Cancer Center - Calgary, Calgary, Alberta, Canada

Cross Cancer Institute, Edmonton, Alberta, Canada

British Columbia Cancer Agency - Vancouver Island Cancer Centre, Victoria, British Columbia, Canada

Doctor Leon Richard Oncology Centre, Moncton, New Brunswick, Canada

Saint John Regional Hospital, Saint John, New Brunswick, Canada

Nova Scotia Cancer Centre, Halifax, Nova Scotia, Canada

Cancer Care Ontario-Hamilton Regional Cancer Centre, Hamilton, Ontario, Canada

Kingston Regional Cancer Centre, Kingston, Ontario, Canada

Cancer Care Ontario-London Regional Cancer Centre, London, Ontario, Canada

Ottawa Regional Cancer Centre - Civic Campus, Ottawa, Ontario, Canada

Northeastern Ontario Regional Cancer Centre, Sudbury, Sudbury, Ontario, Canada

Northwestern Ontario Regional Cancer Centre, Thunder Bay, Thunder Bay, Ontario, Canada

Toronto Sunnybrook Regional Cancer Centre, Toronto, Ontario, Canada

Princess Margaret Hospital, Toronto, Ontario, Canada

Centre Hospitalier de l'Universite de Montreal, Montreal, Quebec, Canada

McGill University Department of Oncology, Montreal, Quebec, Canada

Saskatoon Cancer Centre, Saskatoon, Saskatchewan, Canada

Contact Details

Name: Luis Souhami, MD

Affiliation: McGill Cancer Centre at McGill University

Role: STUDY_CHAIR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

Logo

Take Control of Your Skin and Body Changes Today.

Try out Spots for free, set up only takes 2 mins.

spots app storespots app store

Join others from around the world: