Spots Global Cancer Trial Database for brain and central nervous system tumors
Every month we try and update this database with for brain and central nervous system tumors cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| VNP40101M and Temozolomide in Treating Patients With Progressive or Relapsed Malignant Glioma | NCT00516282 | Brain and Centr... | CLORETAZINE temozolomide | 18 Years - | Northwestern University | |
| Boron Neutron Capture Therapy in Treating Patients With Glioblastoma Multiforme or Melanoma Metastatic to the Brain | NCT00039572 | Brain and Centr... Melanoma (Skin) Metastatic Canc... | boronophenylala... | 18 Years - | National Cancer Institute (NCI) | |
| Radiation Therapy With or Without Temozolomide in Treating Older Patients With Newly Diagnosed Glioblastoma Multiforme | NCT00482677 | Brain and Centr... | temozolomide DNA methylation... quality-of-life... Radiation | 65 Years - 120 Years | Canadian Cancer Trials Group | |
| Changes in Semen or Sperm Caused by Temozolomide in Patients With Newly Diagnosed, Progressive, or Recurrent Primary Malignant Brain Tumors | NCT00499798 | Brain and Centr... Chemotherapeuti... Infertility | 18 Years - 60 Years | Wake Forest University Health Sciences | ||
| ABT-888, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme | NCT00770471 | Brain and Centr... | temozolomide veliparib DNA methylation... gene expression... mutation analys... proteomic profi... high performanc... immunoenzyme te... laboratory biom... mass spectromet... pharmacogenomic... pharmacological... adjuvant therap... radiation thera... | 18 Years - 120 Years | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Radiation Therapy, Temozolomide, and Irinotecan in Treating Patients With Newly Diagnosed Glioblastoma Multiforme | NCT00099125 | Brain and Centr... | irinotecan hydr... temozolomide adjuvant therap... radiation thera... | 18 Years - | Radiation Therapy Oncology Group | |
| Irinotecan Plus Carmustine in Treating Patients With Recurrent Primary Malignant Glioma | NCT00002988 | Brain and Centr... | carmustine irinotecan hydr... | 18 Years - | Duke University | |
| Bispecific Antibody Plus White Blood Cells in Treating Patients With Recurrent or Refractory Glioblastoma Multiforme | NCT00005813 | Brain and Centr... | bispecific anti... lymphokine-acti... conventional su... | 18 Years - | Dartmouth-Hitchcock Medical Center | |
| Suramin in Treating Patients With Recurrent Primary Brain Tumors | NCT00002639 | Brain and Centr... | chemotherapy suramin | 15 Years - | National Cancer Institute (NCI) | |
| Temozolomide in Treating Patients With Primary Brain Tumors or Metastatic Brain Tumors | NCT00547131 | Brain and Centr... Metastatic Canc... | temozolomide laboratory biom... liquid chromato... mass spectromet... pharmacological... conventional su... stereotactic ra... | 18 Years - 120 Years | City of Hope Medical Center | |
| Levetiracetam in Treating Patients With Seizures Caused by Brain Metastases | NCT00415376 | Brain and Centr... Seizure Unspecified Adu... | levetiracetam quality-of-life... | 18 Years - | Northwestern University | |
| Radiation Therapy With and Without Combination Chemotherapy in Patients With Resected Anaplastic Oligodendroglioma | NCT00002840 | Brain and Centr... | lomustine procarbazine hy... vincristine sul... radiation thera... | 16 Years - 69 Years | European Organisation for Research and Treatment of Cancer - EORTC | |
| Chemotherapy in Treating Patients With Recurrent Malignant Glioma | NCT00002986 | Brain and Centr... | carmustine topotecan hydro... | 18 Years - | Duke University | |
| Irinotecan Plus Temozolomide in Treating Patients With Recurrent Primary Malignant Glioma | NCT00005951 | Brain and Centr... | irinotecan hydr... temozolomide | 18 Years - | Duke University | |
| Magnetic Resonance Imaging in Treating Children With Progressive Low-Grade Astrocytoma | NCT00005084 | Brain and Centr... | conventional su... magnetic resona... radiation thera... | - 12 Years | National Cancer Institute (NCI) | |
| Temozolomide, Thalidomide, and Celecoxib Following Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme | NCT00047294 | Brain and Centr... | celecoxib temozolomide thalidomide adjuvant therap... | 18 Years - 120 Years | Dana-Farber Cancer Institute | |
| Temozolomide, Thalidomide, and Celecoxib Following Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme | NCT00047294 | Brain and Centr... | celecoxib temozolomide thalidomide adjuvant therap... | 18 Years - 120 Years | Dana-Farber Cancer Institute | |
| High-Dose Methotrexate in Treating Young Patients With Solid Tumors | NCT00513981 | Brain and Centr... Sarcoma Unspecified Chi... | leucovorin calc... methotrexate mass spectromet... pharmacological... | - 21 Years | National Cancer Institute (NCI) | |
| Carboplatin in Patients With Progressive Gliomas | NCT00002749 | Brain and Centr... | carboplatin | - | Duke University | |
| Tumor Tissue, Blood Samples, and Family History in Predicting Tumor Development and Response to Treatment in Young Patients With Low-Grade Glioma | NCT00891722 | Brain and Centr... | biologic sample... laboratory biom... questionnaire a... | - | National Cancer Institute (NCI) | |
| Calcitriol Plus Carboplatin in Treating Patients With Advanced Solid Tumors | NCT00008086 | Brain and Centr... Unspecified Adu... | calcitriol carboplatin | 18 Years - | University of Pittsburgh | |
| CCI-779 in Treating Patients With Advanced Solid Tumors | NCT00003712 | Brain and Centr... Metastatic Canc... Unspecified Adu... | temsirolimus | 18 Years - | The University of Texas Health Science Center at San Antonio | |
| Leflunomide in Treating Patients With Anaplastic Astrocytoma in First Relapse | NCT00003775 | Brain and Centr... | leflunomide | 18 Years - | Pfizer | |
| Temozolomide Plus Carboplatin in Treating Patients With Recurrent Glioblastoma Multiforme | NCT00021307 | Brain and Centr... | carboplatin temozolomide | 18 Years - | Fox Chase Cancer Center | |
| Rebeccamycin Analogue in Treating Children With Solid Tumors or Non-Hodgkin's Lymphoma | NCT00006102 | Brain and Centr... Lymphoma Neuroblastoma Retinoblastoma Sarcoma Unspecified Chi... | becatecarin | - 21 Years | National Cancer Institute (NCI) | |
| Bispecific Antibody Plus White Blood Cells in Treating Patients With Recurrent or Refractory Glioblastoma Multiforme | NCT00005813 | Brain and Centr... | bispecific anti... lymphokine-acti... conventional su... | 18 Years - | Dartmouth-Hitchcock Medical Center | |
| Photodynamic Therapy With Porfimer Sodium in Treating Patients With Refractory Brain Tumors | NCT00002647 | Brain and Centr... Metastatic Canc... | verteporfin conventional su... | 3 Years - 70 Years | National Cancer Institute (NCI) | |
| Immunotoxin Therapy Before and After Surgery in Treating Patients With Recurrent Malignant Glioma | NCT00036972 | Brain and Centr... | cintredekin bes... adjuvant therap... conventional su... neoadjuvant the... | 18 Years - | National Cancer Institute (NCI) | |
| AEE788 and Everolimus in Treating Patients With Recurrent or Relapsed Glioblastoma Multiforme | NCT00107237 | Brain and Centr... | AEE788 everolimus | 18 Years - | Novartis | |
| Bortezomib and Temozolomide in Treating Patients With Advanced Refractory Solid Tumors or Melanoma | NCT00512798 | Brain and Centr... Melanoma Solid Tumor | PS-341 (VELCADE... temozolomide immunoenzyme te... PS-341 (VELCADE... Temozolomide | 18 Years - | Vanderbilt-Ingram Cancer Center | |
| Motexafin Gadolinium Plus Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme | NCT00003409 | Brain and Centr... | motexafin gadol... radiation thera... | 18 Years - | National Cancer Institute (NCI) | |
| Immunotoxin Therapy in Treating Children With Recurrent Malignant Gliomas | NCT00053040 | Brain and Centr... | cintredekin bes... conventional su... | 3 Years - 21 Years | Pediatric Brain Tumor Consortium | |
| Thiotepa Followed by Peripheral Stem Cell or Bone Marrow Transplant in Treating Patients With Malignant Glioma | NCT00008008 | Brain and Centr... | filgrastim sargramostim cyclophosphamid... thiotepa autologous bone... bone marrow abl... peripheral bloo... | - | National Cancer Institute (NCI) | |
| Temozolomide in Treating Patients With Recurrent or Progressive Malignant Glioma | NCT00004204 | Brain and Centr... | temozolomide | 18 Years - | National Cancer Institute (NCI) | |
| Sirolimus in Treating Patients With Glioblastoma Multiforme | NCT00047073 | Brain and Centr... | Rapamycin Surgery Supportive Care | 18 Years - 120 Years | Jonsson Comprehensive Cancer Center | |
| AXL Inhibitor BGB324 in Treating Participants With Recurrent Glioblastoma Undergoing Surgery | NCT03965494 | Brain and Centr... | BGB 324 (before... BGB 324 (after ... | 18 Years - 120 Years | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Carboplatin Plus Irinotecan in Treating Patients With Glioblastoma Multiforme | NCT00010036 | Brain and Centr... | carboplatin irinotecan hydr... radiation thera... | 18 Years - | NYU Langone Health | |
| Combination Chemotherapy and Bone Marrow Transplantation or Peripheral Stem Cell Transplantation in Treating Patients With Oligodendroglioma | NCT00003101 | Brain and Centr... | filgrastim busulfan lomustine procarbazine hy... thiotepa vincristine sul... autologous bone... peripheral bloo... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Vaccine Therapy in Treating Patients With Malignant Glioma | NCT00612001 | Brain and Centr... | glioma-associat... | 18 Years - | Jonsson Comprehensive Cancer Center | |
| Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation or Bone Marrow Transplantation in Treating Patients With Brain Cancer | NCT00025558 | Brain and Centr... | filgrastim carboplatin temozolomide thiotepa autologous bone... peripheral bloo... | 1 Year - 49 Years | NYU Langone Health | |
| Radiation Therapy and Combination Chemotherapy in Treating Young Patients With Metastatic Medulloblastoma Who Have Undergone Surgery | NCT00276666 | Brain and Centr... | cisplatin lomustine vincristine sul... adjuvant therap... radiation thera... | 3 Years - 21 Years | National Cancer Institute (NCI) | |
| Combination Chemotherapy and Radiation Therapy in Treating Patients With Germ Cell Tumors in the Brain | NCT00293358 | Brain and Centr... | carboplatin cisplatin etoposide phosp... ifosfamide adjuvant therap... conventional su... neoadjuvant the... radiation thera... | - | National Cancer Institute (NCI) | |
| Hydroxychloroquine, Radiation, and Temozolomide Treating Patients With Newly Diagnosed Glioblastoma Multiforme | NCT00486603 | Brain and Centr... | hydroxychloroqu... temozolomide pharmacological... Radiation | 18 Years - 120 Years | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Functional Magnetic Resonance Imaging and 1H-Nuclear Magnetic Resonance Spectroscopic Imaging in Treating Patients With Newly Diagnosed Brain Tumors | NCT00005083 | Brain and Centr... | conventional su... magnetic resona... magnetic resona... | 18 Years - 55 Years | Jonsson Comprehensive Cancer Center | |
| Developing Interview Questions to Estimate Workplace Exposure to Electric and Magnetic Fields | NCT00340054 | Brain and Centr... | questionnaire a... study of high r... | 18 Years - 65 Years | National Institutes of Health Clinical Center (CC) | |
| Tumor Tissue Analysis in Patients Receiving Imatinib Mesylate for Malignant Glioma | NCT00401024 | Brain and Centr... | imatinib mesyla... pharmacological... conventional su... | 18 Years - 120 Years | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Vatalanib in Treating Patients With Recurrent or Progressive Meningioma | NCT00348790 | Brain and Centr... Sarcoma | vatalanib | 18 Years - | Northwestern University | |
| Vaccine Therapy and Sargramostim in Treating Patients With Sarcoma or Brain Tumor | NCT00069940 | Brain and Centr... Gastrointestina... Sarcoma | sargramostim telomerase: 540... | 2 Years - | Dana-Farber Cancer Institute | |
| Bevacizumab in Combination With Metronomic Temozolomide for Recurrent Malignant Glioma | NCT00501891 | Glioblastoma Mu... | Bevacizumab Metronomic Temo... | 18 Years - | Duke University | |
| GP96 Heat Shock Protein-Peptide Complex Vaccine in Treating Patients With Recurrent or Progressive Glioma | NCT00293423 | Brain and Centr... | HSPPC-96 Standard Surgic... | 18 Years - | University of California, San Francisco | |
| Temozolomide in Treating Patients With Recurrent Oligodendroglial Tumors | NCT00003731 | Brain and Centr... | temozolomide | 18 Years - 70 Years | European Organisation for Research and Treatment of Cancer - EORTC | |
| Gimatecan in Treating Patients With Recurrent or Progressive Primary Malignant Glioma | NCT00087061 | Brain and Centr... | gimatecan | 18 Years - | National Cancer Institute (NCI) | |
| Procarbazine in Treating Patients With Recurrent Brain Tumor | NCT00004004 | Brain and Centr... | procarbazine hy... | 18 Years - | National Cancer Institute (NCI) | |
| Radiation Therapy Plus Chemotherapy in Treating Patients With Supratentorial Glioblastoma Multiforme | NCT00002545 | Brain and Centr... | carmustine low-LET photon ... | 18 Years - | Radiation Therapy Oncology Group | |
| A Study Assessing Pamiparib With Radiation and/or Temozolomide (TMZ) in Participants With Newly Diagnosed or Recurrent Glioblastoma | NCT03150862 | Brain and Centr... | Pamiparib TMZ Radiation | 18 Years - | BeiGene | |
| Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Brain Tumors | NCT00003461 | Brain and Centr... Metastatic Canc... Neuroblastoma | surgical proced... astatine At 211... | 18 Years - | Duke University | |
| ATN-161 and Carboplatin in Treating Patients With Recurrent Malignant Glioma | NCT00352313 | Brain and Centr... | ATN-161 carboplatin | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Combination Chemotherapy Followed by Radiation Therapy in Treating Patients With Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Ependymoma | NCT00006258 | Brain and Centr... | filgrastim cisplatin cyclophosphamid... etoposide methotrexate vincristine sul... adjuvant therap... radiation thera... | 10 Years - 65 Years | National Cancer Institute (NCI) | |
| Olaparib and Temozolomide in Treating Patients With Relapsed Glioblastoma | NCT01390571 | Brain and Centr... | olaparib temozolomide gene expression... protein express... laboratory biom... pharmacological... diffusion-weigh... dynamic contras... therapeutic con... | 18 Years - | Cancer Research UK | |
| Radiation Therapy Followed by Carmustine in Treating Patients Who Have Supratentorial Glioblastoma Multiforme | NCT00006386 | Brain and Centr... | carmustine radiation thera... stereotactic ra... | - | Radiation Therapy Oncology Group | |
| MRI Scans in Evaluating the Effects of Radiation Therapy and Chemotherapy in Patients With Newly Diagnosed Glioblastoma Multiforme or Anaplastic Glioma | NCT00756106 | Brain and Centr... | temozolomide Imaging biomark... Photon Radiatio... | 18 Years - | Massachusetts General Hospital | |
| Fenretinide in Treating Patients With Recurrent Malignant Glioma | NCT00006080 | Brain and Centr... | fenretinide | 18 Years - 120 Years | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Carboplatin Plus Irinotecan in Treating Patients With Glioblastoma Multiforme | NCT00010036 | Brain and Centr... | carboplatin irinotecan hydr... radiation thera... | 18 Years - | NYU Langone Health | |
| Melphalan With BBBD in Treating Patients With Brain Malignancies | NCT00253721 | Brain and Centr... Lymphoma Metastatic Canc... | Melphalan | 18 Years - 120 Years | OHSU Knight Cancer Institute | |
| Imatinib Mesylate in Treating Patients With Recurrent Malignant Glioma or Meningioma | NCT00010049 | Brain and Centr... | imatinib mesyla... | 18 Years - 120 Years | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Dalteparin and Radiation Therapy in Treating Patients With Newly Diagnosed Supratentorial Glioblastoma Multiforme | NCT00028678 | Brain and Centr... | dalteparin radiation thera... | 18 Years - 120 Years | Eastern Cooperative Oncology Group | |
| O(6)-Benzylguanine and Temozolomide in Treating Patients With Glioblastoma Multiforme That Did Not Respond to Previous Temozolomide and Radiation Therapy | NCT00436436 | Brain and Centr... | O6-benzylguanin... temozolomide | 18 Years - 120 Years | National Institutes of Health Clinical Center (CC) | |
| Phase II Studies Of Donepezil And Ginkgo Biloba In Irradiated Brain Tumor | NCT00070161 | Brain and Centr... Radiation Toxic... | EGb761 donepezil hydro... cognitive asses... | 18 Years - 120 Years | Wake Forest University Health Sciences | |
| Lymphokine-Activated Killer Cells or Gliadel Wafer in Treating Patients With Newly Diagnosed Glioblastoma Multiforme That Can Be Removed by Surgery | NCT00814593 | Brain and Centr... | lymphokine-acti... polifeprosan 20... | 18 Years - | Lisata Therapeutics, Inc. | |
| High-Dose Thiotepa Plus Peripheral Stem Cell Transplantation in Treating Patients With Refractory Solid Tumors | NCT00003173 | Brain and Centr... Childhood Germ ... Extragonadal Ge... Ovarian Cancer Retinoblastoma Testicular Germ... Unspecified Adu... Unspecified Chi... | filgrastim thiotepa autologous bone... peripheral bloo... | - | Memorial Sloan Kettering Cancer Center | |
| Karenitecin in Treating Patients With Recurrent Malignant Glioma | NCT00014521 | Brain and Centr... | karenitecin | 18 Years - | National Cancer Institute (NCI) | |
| Acridine Carboxamide in Treating Patients With Recurrent Glioblastoma Multiforme | NCT00004937 | Brain and Centr... | acridine carbox... | 18 Years - | European Organisation for Research and Treatment of Cancer - EORTC | |
| Temozolomide and Radiation Therapy in Treating Young Patients With Pontine Glioma | NCT00514397 | Brain and Centr... | motexafin gadol... temozolomide adjuvant therap... quality-of-life... radiation thera... | 2 Years - 21 Years | National Cancer Institute (NCI) | |
| Bevacizumab, Temozolomide, and External Beam Radiation Therapy as First-Line Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma | NCT01013285 | Brain and Centr... | bevacizumab temozolomide external beam r... | 18 Years - | Jonsson Comprehensive Cancer Center | |
| Study of Cerebrospinal Fluid Samples in Diagnosing Carcinomatous Meningitis in Patients With Cancer or Meningeal Syndrome | NCT00938756 | Brain and Centr... Breast Cancer Metastatic Canc... | diagnostic labo... immunoenzyme te... magnetic resona... | 18 Years - | National Cancer Institute (NCI) | |
| EMD 121974 in Treating Patients With Progressive or Recurrent Glioma | NCT00006093 | Brain and Centr... | cilengitide | 18 Years - | National Cancer Institute (NCI) | |
| CT-322 in Treating Patients With Recurrent Glioblastoma Multiforme and Combination Therapy With Irinotecan | NCT00562419 | Brain and Centr... Recurrent Gliob... | CT-322 irinotecan hydr... | 18 Years - | Adnexus, A Bristol-Myers Squibb R&D Company | |
| Chemotherapy in Treating Patients With Progressive or Recurrent Brain Tumors | NCT00012038 | Brain and Centr... | irofulven | 18 Years - | National Cancer Institute (NCI) | |
| Acridine Carboxamide in Treating Patients With Recurrent Glioblastoma Multiforme | NCT00004937 | Brain and Centr... | acridine carbox... | 18 Years - | European Organisation for Research and Treatment of Cancer - EORTC | |
| IL-4(38-37)-PE38KDEL Immunotoxin in Treating Patients With Recurrent Malignant Astrocytoma | NCT00003842 | Brain and Centr... | interleukin-4 P... isolated perfus... surgical proced... | 18 Years - | National Cancer Institute (NCI) |
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