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Spots Global Cancer Trial Database for Ecteinascidin 743 in Treating Patients With Advanced Soft Tissue Sarcoma

The following info and data is provided "as is" to help patients around the globe.
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Trial Identification

Brief Title: Ecteinascidin 743 in Treating Patients With Advanced Soft Tissue Sarcoma

Official Title: Phase II Study on ET-743 in Advanced Soft Tissue Sarcomas of the Adult

Study ID: NCT00003939

Interventions

trabectedin

Study Description

Brief Summary: RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of ecteinascidin 743 in treating patients who have advanced soft tissue sarcoma.

Detailed Description: OBJECTIVES: I. Determine the therapeutic activity of ecteinascidin 743 in patients with advanced soft tissue sarcomas. II. Determine the duration of response in these patients. III. Determine the acute side effects in these patients. OUTLINE: This is a multicenter study. Patients receive ecteinascidin 743 (ET-743) IV over 24 hours every 3 weeks. Treatment continues for at least 2-6 courses in the absence of disease progression or unacceptable toxicity. Patients are followed every 6 weeks until disease progression and every 12 weeks after disease progression. PROJECTED ACCRUAL: Approximately 28-44 patients will be accrued for this study.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Contact Details

Name: Axel Le Cesne, MD

Affiliation: Gustave Roussy, Cancer Campus, Grand Paris

Role: STUDY_CHAIR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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