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Brief Title: Sintilimab Combined With Bevacizumab for Brain Metastases From Non-small Cell Lung Cancer
Official Title: Prospective Phase II Clinical Study of Sintilimab Combined With Bevacizumab for Driving Gene-negative, Asymptomatic Brain Metastases From Non-small Cell Lung Cancer
Study ID: NCT04213170
Brief Summary: This is a prospective phase II clinical study to assess the efficacy of Sintilimab combined with Bevacizumab for driving gene-negative, asymptomatic brain metastases from non-small cell lung cancer by intracranial ORR(iORR),also iPFS,ORR and PFS.The safety and tolerability is evaluated as well.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Sun Yat-sen University of Cancer Center, Guangzhou, Guangdong, China
Name: Likun Chen, doctor
Affiliation: Sun Yat-sen University
Role: STUDY_DIRECTOR