Spots Global Cancer Trial Database for Hippocampal Sparing Whole Brain Radiotherapy vs Conventional Whole Brain Radiotherapy in Patients With Brain Metastases
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Trial Identification
Brief Title: Hippocampal Sparing Whole Brain Radiotherapy vs Conventional Whole Brain Radiotherapy in Patients With Brain Metastases
Official Title: A Randomized Phase II Trial of Hippocampal Sparing Versus Conventional Whole Brain Radiotherapy After Surgical Resection or Radiosurgery in Favourable Prognosis Patients With 1-10 Brain Metastases
Study ID: NCT02147028
Conditions
Study Description
Brief Summary: The purpose of this study is to evaluate whether sparing the hippocampi during whole brain radiotherapy following neurosurgery or stereotactic radiosurgery in patients with brain metastases from a systemic tumour helps preserve brain function.
Detailed Description:
Eligibility
Minimum Age: 16 Years
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
University Hospitals Birmingham NHS Foundation Trust, Birmingham, Greater London, United Kingdom
Addenbrooke's Hospital, Cambridge, , United Kingdom
Royal Surrey County Hospital, Guildford, , United Kingdom
Charing Cross Hospital, London, , United Kingdom
The Christie NHS Foundation Trust, Manchester, , United Kingdom
Nottingham University Hospitals, Nottingham, , United Kingdom
Barking, Havering and Redbridge University Hospitals Nhs Trust, Romford, , United Kingdom
Contact Details
Name: Gillian Whitfield, MA,MB BS,PhD
Affiliation: The Christie NHS Foundation Trust
Role: STUDY_CHAIR
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