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Spots Global Cancer Trial Database for SRS for NSCLC With Oligo-residual Intracranial Disease After First-line 3rd Generation EGFR-TKI

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Trial Identification

Brief Title: SRS for NSCLC With Oligo-residual Intracranial Disease After First-line 3rd Generation EGFR-TKI

Official Title: Stereotactic Radiotherapy for Non-small Cell Lung Cancer With Oligo-residual Intracranial Disease After First-line Third-generation EGFR Inhibitors: a Multicenter, Randomized Clinical Trial.

Study ID: NCT06020066

Study Description

Brief Summary: Despite the impressive response rate to third-generation EGFR-TKIs, resistance inevitably develops in most patients. Stereotactic radiotherapy plays a growing role in the management of patients with brain metastasis. This study aims to evaluate the efficacy and safety of stereotactic radiotherapy for oligo-residual intracranial disease after first-line third-generation EGFR Inhibitors.

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Fudan University Shanghai Cancer Center, Shanghai, Shanghai, China

Contact Details

Name: Zhengfei Zhu, MD

Affiliation: Fudan University

Role: PRINCIPAL_INVESTIGATOR

Name: Xuwei Cai

Affiliation: Shanghai Chest Hospital

Role: PRINCIPAL_INVESTIGATOR

Name: Qian Chu

Affiliation: Tongji Hospital

Role: PRINCIPAL_INVESTIGATOR

Name: Xiaorong Dong

Affiliation: Wuhan Union Hospital, China

Role: PRINCIPAL_INVESTIGATOR

Name: Lin Wu

Affiliation: Hunan Cancer Hospital

Role: PRINCIPAL_INVESTIGATOR

Name: Rongrong Zhou

Affiliation: Xiangya Hospital of Central South University

Role: PRINCIPAL_INVESTIGATOR

Name: Guang Han

Affiliation: Hubei Cancer Hospital

Role: PRINCIPAL_INVESTIGATOR

Name: Hui Zhu

Affiliation: Shandong Cancer Hospital and Institute

Role: PRINCIPAL_INVESTIGATOR

Name: Jinjun Ye

Affiliation: Jiangsu Cancer Institute & Hospital

Role: PRINCIPAL_INVESTIGATOR

Name: Xiaojia Cui

Affiliation: The Affiliated Tumor Hospital of Nantong University, Nantong, Jiangsu Province, China

Role: PRINCIPAL_INVESTIGATOR

Name: Guomei Tai

Affiliation: The Affiliated Tumor Hospital of Nantong University, Nantong, Jiangsu Province, China

Role: PRINCIPAL_INVESTIGATOR

Name: Zhiyong Yuan

Affiliation: Tianjin Medical University Cancer Institute and Hospital

Role: PRINCIPAL_INVESTIGATOR

Name: Dejun XIng

Affiliation: Jilin Provincial Tumor Hospital

Role: PRINCIPAL_INVESTIGATOR

Name: Jichen Ren

Affiliation: Jilin Provincial Tumor Hospital

Role: PRINCIPAL_INVESTIGATOR

Name: Jiancheng Li

Affiliation: Fujian Medical University Cancer Hospital

Role: PRINCIPAL_INVESTIGATOR

Name: Yanyang Wang

Affiliation: General Hospital of Ningxia Medical University

Role: PRINCIPAL_INVESTIGATOR

Name: Chuangzhou Rao

Affiliation: Ningbo No.2 Hospital

Role: PRINCIPAL_INVESTIGATOR

Name: Bing Lu

Affiliation: The Affiliated Hospital Of Guizhou Medical University

Role: PRINCIPAL_INVESTIGATOR

Name: Zhongyi Dong

Affiliation: Nanfang Hospital, Southern Medical University

Role: PRINCIPAL_INVESTIGATOR

Name: Jiwei Liu

Affiliation: The First Affiliated Hospital of Dalian Medical University

Role: PRINCIPAL_INVESTIGATOR

Name: Zhenzhou Yang

Affiliation: The Second Affiliated Hospital of Chongqing Medical University

Role: PRINCIPAL_INVESTIGATOR

Name: Hongqing Zhuang

Affiliation: Peking University Third Hospital

Role: PRINCIPAL_INVESTIGATOR

Name: Anwen Liu

Affiliation: Nanchang University Second Affiliated Hospital

Role: PRINCIPAL_INVESTIGATOR

Name: Haihua Yang

Affiliation: Taizhou Hospital Affiliated to Wenzhou Medical University

Role: PRINCIPAL_INVESTIGATOR

Name: Fang Liu

Affiliation: Chinese PLA General Hospital

Role: PRINCIPAL_INVESTIGATOR

Name: Yong Mao

Affiliation: Affiliated Hospital of Jiangnan University

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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