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Brief Title: Study to Establish the Diagnostic Performance of 18F Fluciclovine PET in Detecting Recurrent Brain Metastases
Official Title: An Open-label, Single-arm, Single-dose, Prospective, Multicenter Phase 3 Study to Establish the Diagnostic Performance of 18F-Fluciclovine Positron Emission Tomography (PET) in Detecting Recurrent Brain Metastases After Radiation Therapy
Study ID: NCT04410133
Brief Summary: An open-label, single dose, single arm, prospective, multicenter Phase 3 study to establish the diagnostic performance of 18F fluciclovine positron emission tomography (PET) in detecting recurrent brain metastases after radiation therapy
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
University of Alabama at Birmingham, Birmingham, Alabama, United States
St. Joseph's Hospital and Medical Center, Phoenix, Arizona, United States
University of California, San Francisco, San Francisco, California, United States
John Wayne Cancer Institute at Providence St. John's Health Center, Santa Monica, California, United States
Yale School of Medicine, New Haven, Connecticut, United States
Miami Cancer Institute at Baptist Health, Inc., Miami, Florida, United States
Medical College of Georgia, Augusta University, Augusta, Georgia, United States
Ochsner Clinic Foundation, New Orleans, Louisiana, United States
Johns Hopkins Hospital, Baltimore, Maryland, United States
University of Michigan Rogel Cancer Center, Ann Arbor, Michigan, United States
Henry Ford Hospital, Detroit, Michigan, United States
Washington University School of Medicine-Center for Clinical Imaging Research, Saint Louis, Missouri, United States
NYU Langone Health, New York, New York, United States
University Hospital Cleveland, Cleveland, Ohio, United States
Cleveland Clinic, Cleveland, Ohio, United States
University of Pennsylvania Health System, Philadelphia, Pennsylvania, United States
The University of Texas MD Anderson Cancer Center, Houston, Texas, United States
Center for Quantitative Cancer Imaging at Huntsman Cancer Institute, Salt Lake City, Utah, United States
West Virgina University Cancer Institute, Morgantown, West Virginia, United States