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Brief Title: MRI Study of Radiation-Induced Damage to White Matter and Blood-Brain-Barrier
Official Title: MRI Study of Radiation-Induced Damage to White Matter and Blood-Brain-Barrier
Study ID: NCT01988675
Brief Summary: This is a study to determine if Magnetic Resonance Imaging (MRI) techniques can detect early changes in white matter (in the brain) and the blood-brain barrier resulting from radiation therapy.
Detailed Description: Patients will be assigned to one of two groups based on the type of radiation they will be receiving: whole brain irradiation or partial brain irradiation. Patients will undergo Magnetic Resonance Imaging (MRI) assessments, neurocognitive testing (Quality of Life and Neuropsychological assessments), and clinical evaluation.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
University of Michigan Hosptial, Ann Arbor, Michigan, United States
Name: Yue Cao, Ph.D.
Affiliation: University of Michigan
Role: PRINCIPAL_INVESTIGATOR