Spots Global Cancer Trial Database for brain neoplasms
Every month we try and update this database with for brain neoplasms cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Iressa in the Treatment of Brain Metastases From Non Small Cell Lung Cancer | NCT00234442 | Brain Neoplasms Non Small Cell ... | Iressa (Gefitin... | 18 Years - | AstraZeneca | |
| Study of Abemaciclib and Elacestrant in Patients With Brain Metastasis Due to HR+/HER2- Breast Cancer | NCT05386108 | Breast Neoplasm... Brain Neoplasms Neoplasms by Si... Neoplasms Breast Diseases Central Nervous... Brain Diseases Central Nervous... | Elacestrant Abemaciclib | 18 Years - | Stemline Therapeutics, Inc. | |
| NovoTTF Therapy in Treating Patients With Recurrent Glioblastoma Multiforme | NCT01954576 | Glioblastoma Brain Neoplasms | NovoTTF-100A Quality-of-life... Laboratory biom... | 22 Years - | University of Florida | |
| BRAINFUL (BRAIN Tumor Focused Ultrasound-enabled Liquid Biopsy) Trial | NCT04940507 | Brain Neoplasms Liquid Biopsy | Magnetic Resona... Magnetic Resona... | 18 Years - | University Health Network, Toronto | |
| Functional Outcomes of The Bobath Approach on Patients With Brain Tumors: Comparison With Stroke Patients | NCT03574467 | Brain Neoplasms Stroke, Acute | Bobath Neurodev... | 18 Years - | Hacettepe University | |
| Phase I/II Bevacizumab Versus Bevacizumab Plus TPI 287 for Recurrent Glioblastoma | NCT01582152 | Brain Neoplasms Central Nervous... | TPI287 Bevacizumab | 18 Years - | M.D. Anderson Cancer Center | |
| Multi-modality Localization of Eloquent Brain Function | NCT02795338 | Brain Neoplasms | brain mapping | 19 Years - | University of Nebraska | |
| Hypovitaminosis D in Neurocritical Patients | NCT02881957 | Craniocerebral ... Intracranial An... Brain Neoplasms Spinal Cord Inj... Seizures Meningitis Stroke Intracranial He... Critical Illnes... Vitamin d Defic... | Cholecalciferol Placebo | 18 Years - | University of Utah | |
| Phase II Randomized Study of Stereotactic Radiosurgery Plus Fractionated Whole-Brain Radiotherapy Vs Fractionated Whole-Brain Radiotherapy Alone for Multiple Primary or Metastatic Brain Tumors | NCT00004659 | Brain Neoplasms | irradiation radiosurgery | 0 Years - | Office of Rare Diseases (ORD) | |
| A Study of the Specificity and Sensitivity of 5-ALA Fluorescence in Malignant Brain Tumors | NCT00977795 | Brain Neoplasms | 5-aminolevulini... | 18 Years - | NorthShore University HealthSystem | |
| Study of Temozolomide in the Treatment of Brain Metastasis From Non-small-cell Lung Cancer (Study P02143) | NCT00034697 | Metastases, Neo... Carcinoma, Non-... Brain Neoplasms | temozolomide | 18 Years - | Merck Sharp & Dohme LLC | |
| SPECTAbrain: Screening Patients With Brain Tumors for Efficient Clinical Trial Access | NCT02307604 | Brain Neoplasms | Tumour markers ... | 18 Years - | European Organisation for Research and Treatment of Cancer - EORTC | |
| Functional Outcomes of The Bobath Approach on Patients With Brain Tumors: Comparison With Stroke Patients | NCT03574467 | Brain Neoplasms Stroke, Acute | Bobath Neurodev... | 18 Years - | Hacettepe University | |
| Phase I/II Evaluation of Temozolomide and ZARNESTRA (R115777) for Recurrent and Progressive Glioblastoma Multiforme | NCT00050986 | Glioblastoma Mu... | Temozolomide R115777 | - | M.D. Anderson Cancer Center | |
| A FIH Study of PF-07284890 in Participants With BRAF V600 Mutant Solid Tumors With and Without Brain Involvement | NCT04543188 | Malignant Melan... Carcinoma, Non-... Brain Neoplasms... Brain Neoplasms Malignant Neopl... | PF-07284890 Binimetinib Midazolam | 16 Years - | Pfizer | |
| Therapeutic Benefit of Preoperative Supplemental Vitamin D in Patients Undergoing Brain Tumor Surgery | NCT03248544 | Brain Neoplasms | vitamin D control | 18 Years - | Shahid Beheshti University | |
| MRI Study of Radiation-Induced Damage to White Matter and Blood-Brain-Barrier | NCT01988675 | Brain Neoplasms | Whole Brain Irr... Partial Brain I... Neuropsychologi... Quality of Life... Magnetic Resona... | 18 Years - | University of Michigan Rogel Cancer Center | |
| A Study of the Specificity and Sensitivity of 5- Aminolevulinic Acid (ALA) Fluorescence in Malignant Brain Tumors | NCT01128218 | Brain Neoplasms | Tumor fluoresce... | 18 Years - | Southern Illinois University | |
| Study of 111In-DAC as an Medical Imaging Agent for Lung Cancer and Brain Cancer Consistent With Metastatic Lung Cancer | NCT00040560 | Lung Neoplasms Carcinoma, Non-... Brain Neoplasms Metastases, Neo... | 111In-DAC Diagnostic | 18 Years - | Copharos | |
| Multiple Dose Study of MPC-6827 in Subjects With Refractory Brain Metastases | NCT00393965 | Brain Neoplasms | MPC-6827 | 18 Years - | Myrexis Inc. | |
| Re-craniotomy and Complications After Elective Neurosurgery | NCT03910556 | Brain Tumor Brain Metastase... Brain Cancer Brain Neoplasms | Propofol | 18 Years - 75 Years | Chiang Mai University | |
| DETERMINE Trial Treatment Arm 03: Entrectinib in Adult, Teenage/Young Adults and Paediatric Patients With ROS1 Gene Fusion-positive Cancers. | NCT05770544 | Solid Tumor Haematological ... Malignancy Malignant Neopl... Lymphoprolifera... Neoplasms by Hi... Neoplasms by Si... Cancer Brain Neoplasms Melanoma Glioma | Entrectinib | - | Cancer Research UK | |
| A Study to Learn About the Study Medicine Called PF-07799544 in People With Advanced Solid Tumors | NCT05538130 | Melanoma Glioma Thyroid Cancer Non-Small Cell ... Malignant Neopl... Brain Neoplasms Colorectal Canc... | PF-07799544 PF-07799933 encorafenib | 16 Years - | Pfizer | |
| Study of Abemaciclib and Elacestrant in Patients With Brain Metastasis Due to HR+/HER2- Breast Cancer | NCT05386108 | Breast Neoplasm... Brain Neoplasms Neoplasms by Si... Neoplasms Breast Diseases Central Nervous... Brain Diseases Central Nervous... | Elacestrant Abemaciclib | 18 Years - | Stemline Therapeutics, Inc. | |
| Clinical Evaluation of Navigated 3D Ultrasound Multicentre Study | NCT00233350 | Brain Neoplasms | use of navigate... | 18 Years - | Norwegian University of Science and Technology | |
| Platelets Activation in Brain Neoplasms | NCT05049148 | Glioma Blood Platelets Inflammation Brain Neoplasms | Platelet count ... | 18 Years - | Fondation Ophtalmologique Adolphe de Rothschild | |
| Phase II Trial of Sequential Chemotherapy and Radiotherapy for AIDS-Related Primary Central Nervous System Lymphoma | NCT00000801 | Lymphoma, Non-H... HIV Infections | Filgrastim Vincristine sul... Doxorubicin hyd... Cyclophosphamid... Cytarabine Dexamethasone | 16 Years - | National Institute of Allergy and Infectious Diseases (NIAID) | |
| A Study of Bevacizumab in Combination With First- or Second-Line Therapy in Subjects With Treated Brain Metastases Due to Non-Squamous NSCLC (PASSPORT) | NCT00312728 | Non-Small Cell ... Brain Neoplasms | bevacizumab First-Line Chem... Second-Line Che... | 18 Years - | Genentech, Inc. | |
| Role of MR Spectroscopy in Brain Tumors | NCT03619694 | Brain Neoplasms | MRI Spectroscop... | 18 Years - 75 Years | Assiut University | |
| Small-dose Dexmedetomidine Effects on Recovery Profiles of Supratentorial Tumors Patients From General Anesthesia | NCT02007798 | Brain Neoplasms Surgery | dexmedetomidine normal saline | 35 Years - 65 Years | China Medical University, China | |
| Study To Test the Safety and Efficacy of TVI-Brain-1 As A Treatment for Recurrent Grade IV Glioma | NCT01290692 | Grade IV Glioma Grade IV Astroc... Glioblastoma Mu... | TVI-Brain-1 | 18 Years - | TVAX Biomedical | |
| Assessing Dynamic Magnetic Resonance (MR) Imaging in Patients With Recurrent High Grade Glioma Receiving Chemotherapy | NCT00769093 | Brain Neoplasms | Ferumoxytol | 18 Years - 75 Years | OHSU Knight Cancer Institute | |
| Local Radiotherapy Following Complete Resection of a Brain Metastasis | NCT02729558 | Brain Neoplasms | local SRT | 18 Years - | Amsterdam UMC, location VUmc | |
| A Study to Evaluate the Safety, Tolerability and Immunogenicity of EGFR(V)-EDV-Dox in Subjects With Recurrent Glioblastoma Multiforme (GBM) | NCT02766699 | Glioblastoma Astrocytoma, Gr... | EGFR(V)-EDV-Dox | 18 Years - | Engeneic Pty Limited | |
| Robotic Compared to Fixed Gantry Radiosurgery for Brain Metastases | NCT01353573 | Metastatic Mali... | Fixed Gantry Ra... Robotic Radiosu... | 18 Years - | Hamilton Health Sciences Corporation | |
| Embolization for Meningioma | NCT05416567 | Meningioma | Endovascular em... | 18 Years - | St. Olavs Hospital | |
| FLT-PET Imaging of Brain Tumors in Children | NCT01244737 | Brain Neoplasms | [18F] FLT | - 21 Years | Boston Children's Hospital | |
| Health Related Quality of Life in Pediatric Central Nervous System (CNS) Tumors: A Feasibility Study Utilizing PROMIS | NCT02603692 | Brain Neoplasms | PROMIS-QOL | 5 Years - 35 Years | Children's Hospital Medical Center, Cincinnati | |
| Clinical Evaluation of Navigated 3D Ultrasound Multicentre Study | NCT00233350 | Brain Neoplasms | use of navigate... | 18 Years - | Norwegian University of Science and Technology | |
| An Evaluation of a Non-invasive Brain Monitor | NCT02775136 | Brain Injuries Subarachnoid He... Vasospasm, Intr... Hydrocephalus Brain Neoplasms | HS-1000 recordi... | 18 Years - | HeadSense Medical | |
| Multi-modality Localization of Eloquent Brain Function | NCT02795338 | Brain Neoplasms | brain mapping | 19 Years - | University of Nebraska | |
| Dexmedetomidine and Intelligence Development in Pediatric Patients Undergoing Craniotomy | NCT02810899 | Brain Neoplasms | dexmedetomidine normal saline | 2 Years - 12 Years | Peking University First Hospital | |
| Functional Outcomes of The Bobath Approach on Patients With Brain Tumors: Comparison With Stroke Patients | NCT03574467 | Brain Neoplasms Stroke, Acute | Bobath Neurodev... | 18 Years - | Hacettepe University | |
| Phase II Trial of Sequential Chemotherapy and Radiotherapy for AIDS-Related Primary Central Nervous System Lymphoma | NCT00000801 | Lymphoma, Non-H... HIV Infections | Filgrastim Vincristine sul... Doxorubicin hyd... Cyclophosphamid... Cytarabine Dexamethasone | 16 Years - | National Institute of Allergy and Infectious Diseases (NIAID) | |
| A Phase I Study of ABT-888 in Combination With Conventional Whole Brain Radiation Therapy (WBRT) in Cancer Patients With Brain Metastases | NCT00649207 | Brain Diseases Brain Neoplasms Central Nervous... Neoplasm Metast... Nervous System ... | ABT-888 Whole Brain Rad... | 18 Years - 99 Years | AbbVie | |
| Prognosis Prediction System of Patients With Cardiovascular and Cerebrovascular Diseases Based on Multi-omics | NCT06001073 | Coronary Artery... Arrhythmias, Ca... Heart Valve Dis... Aortic Dissecti... Heart Neoplasms Myocarditis Hypertension Cardiomyopathie... Structural Hear... Ischemic Cerebr... Hemorrhagic Cer... Brain Neoplasms | Observational; ... | 3 Years - 80 Years | First Affiliated Hospital Xi'an Jiaotong University | |
| Social Cognition in Children Treated for a Brain Tumour | NCT01599052 | Social Behaviou... Brain Neoplasms Cystic Fibrosis | 5 Years - 12 Years | University Medical Center Groningen | ||
| Iressa in the Treatment of Brain Metastases From Non Small Cell Lung Cancer | NCT00234442 | Brain Neoplasms Non Small Cell ... | Iressa (Gefitin... | 18 Years - | AstraZeneca | |
| Magnevist (SH L 451A) Intra-individual Dose Comparison Study in Patients With Brain Metastasis | NCT00681551 | Brain Neoplasms | Magnevist (SH L... Magnevist (SH L... | 20 Years - | Bayer | |
| The Effect of Vitamin D3 on Postoperative Pain in Patients Undergoing Craniotomy | NCT03614403 | Brain Neoplasms | vitamin D | 18 Years - 80 Years | Shahid Beheshti University | |
| Determination of Fraction Size Equivalent Dose (FED) Levels for Intracranial Conformal Avoidance Radiotherapy | NCT00214175 | Glioma Brain Neoplasms | 18 Years - | University of Wisconsin, Madison | ||
| 18F-fluorodeoxyglucose (18F-FDG) Positron Emission Tomography in Oncology | NCT00207298 | Brain Neoplasms Lung Neoplasms Lymphoma Melanoma Colorectal Neop... | Positron Emissi... | 19 Years - 90 Years | British Columbia Cancer Agency | |
| SGM-101 in Colorectal Brain Metastases. | NCT04755920 | Rectal Neoplasm... Rectum Cancer Colorectal Neop... Brain Metastase... Brain Neoplasms Brain Diseases Brain Cancer Brain Tumor Intestinal Neop... Gastrointestina... Gastrointestina... Gastrointestina... Intestinal Dise... | SGM-101 | 18 Years - | Leiden University Medical Center | |
| Effectiveness of Musical Training in Children Surviving Brain Tumours | NCT02754908 | Brain Neoplasms Child | musical trainin... tutoring classe... | 7 Years - 19 Years | The University of Hong Kong | |
| Imaging Study of the Distribution of IL13-PE38QQR Infused Before and After Surgery in Adult Patients With Recurrent Malignant Glioma | NCT00064779 | Malignant Gliom... Glioblastoma Mu... Anaplastic Astr... Anaplastic Olig... Mixed Oligoastr... | IL13-PE38QQR targeted fusion... surgery | 18 Years - | INSYS Therapeutics Inc | |
| Neurocognition After Gamma Knife Radiosurgery for Multiple Brian Metastases | NCT01970644 | Neoplasm Metast... | Gamma knife rad... | 18 Years - | CancerCare Manitoba | |
| In Vivo Confocal Endomicroscopy of the Brain | NCT00949793 | Brain Neoplasms | Endomicroscope | 18 Years - | Carl Zeiss Surgical GmbH | |
| Local Radiotherapy Following Complete Resection of a Brain Metastasis | NCT02729558 | Brain Neoplasms | local SRT | 18 Years - | Amsterdam UMC, location VUmc | |
| Embolization for Meningioma | NCT05416567 | Meningioma | Endovascular em... | 18 Years - | St. Olavs Hospital | |
| A Home-Based Approach Study to Evaluate the Efficacy and Safety of Alectinib in Locally-Advanced or Metastatic ALK-Positive Solid Tumors | NCT04644315 | Neoplasms Colorectal Neop... Melanoma Pancreatic Neop... Sarcoma Ovarian Neoplas... Brain Neoplasms Thyroid Neoplas... Neuroendocrine ... Cholangiocarcin... Salivary Gland ... Head and Neck N... Thyroid Cancer,... Lymphoma, Large... Neoplasms by Si... Respiratory Tra... Thoracic Neopla... Respiratory Tra... Carcinoma, Bron... Bronchial Neopl... Intestinal Neop... Gastrointestina... Digestive Syste... Digestive Syste... Gastrointestina... Colonic Disease... Intestinal Dise... Central Nervous... | Alectinib | 18 Years - | Hoffmann-La Roche | |
| In Vivo Confocal Microscopy Tumor Atlas Study | NCT01012154 | Brain Neoplasms | Endomicroscope | 18 Years - | Carl Zeiss Surgical GmbH | |
| Study of Oral JYP0322 in Patients With Locally Advanced or Metastatic Cancer Targeting ROS1 Molecular Fusion. | NCT06128148 | Protein Kinase ... Other Protocol ... Lung Neoplasms Brain Neoplasms | JYP0322 | 18 Years - | Guangzhou JOYO Pharma Co., Ltd | |
| An Evaluation of a Non-invasive Brain Monitor | NCT02775136 | Brain Injuries Subarachnoid He... Vasospasm, Intr... Hydrocephalus Brain Neoplasms | HS-1000 recordi... | 18 Years - | HeadSense Medical | |
| Stereotactic Radiosurgery to the Resection Cavity Following Surgical Removal of Brain Metastasis | NCT00484978 | Brain Neoplasms | Stereotactic Ra... | 18 Years - | Tel-Aviv Sourasky Medical Center | |
| Whole Brain Radiotherapy With or Without Temozolomide at Daily Fixed-dose for Brain Metastases Treatment | NCT01015534 | Brain Neoplasms | Temozolomide Whole brain irr... | 18 Years - 80 Years | Instituto Nacional de Cancerologia de Mexico | |
| Imaging of Intravenous (IV) Combidex to Brain, Intra-cerebral Tumors and in Central Nervous System (CNS) Inflammation | NCT00659334 | Brain Neoplasms | Ferumoxtran-10 ... Neurosurgery | 5 Years - 75 Years | OHSU Knight Cancer Institute | |
| Comparison of 6-fluoro-[18F]-L-dihydroxyphenylalanine (18F-DOPA) Positron Emission Tomography (PET) and Multiparametric Resonance Magnetic Imagery (RMI) in Initial Exploration of Glial Tumors | NCT03525080 | Brain Neoplasms Adult Brain Tum... | PET imagery | 18 Years - | Center Eugene Marquis | |
| Evaluation of Anatomy, Clinical and Neuropsychological Long-term Sequelae of Patients Treated With Radiation Therapy for Brain Tumor | NCT02791360 | Brain Neoplasms | Brain MRI | 18 Years - | Centre Francois Baclesse | |
| In Vivo Confocal Microscopy Tumor Atlas Study | NCT01012154 | Brain Neoplasms | Endomicroscope | 18 Years - | Carl Zeiss Surgical GmbH | |
| Effectiveness of Musical Training in Hong Kong Chinese Childhood Brain Tumor Survivors | NCT03399864 | Brain Neoplasms Child | musical trainin... usual care | 7 Years - 16 Years | The University of Hong Kong | |
| Phase II Trial of Sequential Chemotherapy and Radiotherapy for AIDS-Related Primary Central Nervous System Lymphoma | NCT00000801 | Lymphoma, Non-H... HIV Infections | Filgrastim Vincristine sul... Doxorubicin hyd... Cyclophosphamid... Cytarabine Dexamethasone | 16 Years - | National Institute of Allergy and Infectious Diseases (NIAID) | |
| Fluid Therapy During Brain Tumor Resection in Children | NCT02707549 | Brain Neoplasms | balanced crysta... 0.9% sodium chl... | 6 Months - 12 Years | Federal University of São Paulo | |
| Guided Meditation During Radiation Therapy for Brain Tumors | NCT06165653 | Brain Neoplasms | 5-Minute, Audio... | 18 Years - | University of Utah | |
| Efficiency of Two Glucose Sampling Protocols for Maintenance of Euglycemia | NCT00993057 | Brain Neoplasms Intracranial An... | Insulin | 18 Years - | Northwestern University | |
| DNX-2401 With Interferon Gamma (IFN-γ) for Recurrent Glioblastoma or Gliosarcoma Brain Tumors | NCT02197169 | Glioblastoma or... | Single intratum... Interferon-gamm... | 18 Years - | DNAtrix, Inc. | |
| Study of Genistein in Pediatric Oncology Patients (UVA-Gen001) | NCT02624388 | Lymphoma Childhood Lymph... Solid Tumor Childhood Solid... Neuroblastoma Ewing Sarcoma Hodgkin Lymphom... Non-Hodgkin Lym... Rhabdomyosarcom... Soft Tissue Sar... Medulloblastoma Germ Cell Tumor Wilms Tumor Brain Neoplasms Medulloblastoma... Neuroectodermal... | Genistein Placebo | 1 Year - 21 Years | University of Virginia | |
| Imaging of Intravenous (IV) Combidex to Brain, Intra-cerebral Tumors and in Central Nervous System (CNS) Inflammation | NCT00659334 | Brain Neoplasms | Ferumoxtran-10 ... Neurosurgery | 5 Years - 75 Years | OHSU Knight Cancer Institute | |
| Imaging Study of the Distribution of IL13-PE38QQR Infused Before and After Surgery in Adult Patients With Recurrent Malignant Glioma | NCT00064779 | Malignant Gliom... Glioblastoma Mu... Anaplastic Astr... Anaplastic Olig... Mixed Oligoastr... | IL13-PE38QQR targeted fusion... surgery | 18 Years - | INSYS Therapeutics Inc | |
| Pilot Study of Vardenafil and Carboplatin in Patients With Gliomas and Brain Metastases | NCT02279992 | Glioma Brain Neoplasms Brain Metastasi... | Vardenafil Carboplatin | 18 Years - | Cedars-Sinai Medical Center | |
| Bevacizumab and Erlotinib in Lung Cancer With Brain Metastases, a Phase II Trial | NCT02655536 | Carcinoma, Non-... Brain Neoplasms | Bevacizumab plu... Erlotinib | 20 Years - 99 Years | National Taiwan University Hospital |
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