Spots Global Cancer Trial Database for Factor XIII and Pulmonary Embolism in Neurosurgical Patients
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Trial Identification
Brief Title: Factor XIII and Pulmonary Embolism in Neurosurgical Patients
Official Title: Risk Factors for Perioperative Pulmonary Embolism in Neurosurgical Patients in Respect of Factor XIII Activity
Study ID: NCT01106937
Interventions
Study Description
Brief Summary: Two studies (Gerlach et al. 2000; Gerlach et al. 2002) described the impact of factor XIII on the risk of prospective hemorrhage for patients undergoing craniotomy. Since then, factor XIII is measured and substituted in various centers. Few reports support the idea of factor XIII being involved in the formation of deep venous thrombosis and pulmonary embolism. In this prospective observational study, patients undergoing craniotomy for brain tumors or vascular lesions are investigated concerning the incidence of postoperative pulmonary embolism in respect of possible risk factors (factor XIII activity levels, standard coagulation parameters, tumor entity, blood loss).
Detailed Description:
Keywords
Eligibility
Minimum Age:
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Department of Neurosurgery, LMU, Munich, Bavaria, Germany
Contact Details
Name: Stefan Grau, Dr.
Affiliation: Ludwig-Maximilians - University of Munich
Role: PRINCIPAL_INVESTIGATOR
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