Spots Global Cancer Trial Database for brain tumor
Every month we try and update this database with for brain tumor cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Ph II Erlotinib + Sirolimus for Pts w Recurrent Malignant Glioma Multiforme | NCT00672243 | Glioblastoma Gliosarcoma | Erlotinib + sir... | 18 Years - | Duke University | |
| A Trial of Poly-ICLC in the Management of Recurrent Pediatric Low Grade Gliomas | NCT01188096 | Brain Tumors | Poly ICLC | - 21 Years | Wake Forest University Health Sciences | |
| Methotrexate Infusion Into Fourth Ventricle in Children With Recurrent Malignant Fourth Ventricular Brain Tumors | NCT02458339 | Brain Tumor, Re... Malignant Neopl... | Ommaya Reservoi... Methotrexate | 1 Year - 21 Years | The University of Texas Health Science Center, Houston | |
| An Open Label Dose Escalation Safety Study of Convection-Enhanced Delivery of IL13-PE38QQR in Patients With Progressive Pediatric Diffuse Infiltrating Brainstem Glioma and Supratentorial High-grade Glioma | NCT00880061 | Brain Neoplasm Glioma | IL13-PE38QQR | - 17 Years | National Institutes of Health Clinical Center (CC) | |
| A Phase II Trial of Intensity-Modulated Proton Therapy for Incompletely Resected Craniopharyngioma and Observation for Craniopharyngioma After Radical Resection | NCT02792582 | Craniopharyngio... | Proton Therapy Surgery | - 21 Years | St. Jude Children's Research Hospital | |
| Effect of Preemptive Low Dose Norepinephrine Infusion on Intraoperative Hemodynamic Stability and Postoperative Outcomes in Patients Undergoing Brain Tumor Resection With a Craniotomy | NCT05814601 | Brain Tumor | norepinephrine | 20 Years - 65 Years | Yonsei University | |
| Evaluation of Fluoxetine and Cytotoxic Lysosomal Stress in Glioma (FLIRT) | NCT05634707 | Primary Brain T... Brain Tumor, Re... | Fluoxetine Temozolomide | 24 Years - | Duke University | |
| Functional Navigation in Surgery of Cerebral Tumors and Vascular Malformations | NCT05484219 | Tumor, Brain Arteriovenous M... Cavernoma | Functional navi... | 18 Years - 79 Years | Sklifosovsky Institute of Emergency Care | |
| The Neuro-protective Effects of Exercise in Children With Brain Tumors | NCT01944761 | Brain Tumor | Exercise Progra... | 7 Years - 17 Years | The Hospital for Sick Children | |
| Phase II Study of Temozolomide in Newly Diagnosed Glioblastoma | NCT00365222 | Glioblastoma Gliosarcoma | Temozolomide | 70 Years - | H. Lee Moffitt Cancer Center and Research Institute | |
| Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer | NCT05106296 | Ependymoma Medulloblastoma Glioblastoma Primary Brain T... | Ibrutinib Indoximod Cyclophosphamid... Etoposide | 12 Years - 25 Years | Augusta University | |
| Feasibility Study of Modified Atkins Ketogenic Diet in the Treatment of Newly Diagnosed Malignant Glioma | NCT03278249 | Glioblastoma | Modified Atkins... | 18 Years - | University of Cincinnati | |
| Biomarker Analysis of Central Nervous System Tumors | NCT02692898 | Central Nervous... Primary Brain N... Neoplasms, Brai... Cancer of the B... Brain Cancer | - 99 Years | National Institutes of Health Clinical Center (CC) | ||
| Phase II Trial of Peginterferon Alpha-2b and Thalidomide in Adults With Recurrent Gliomas | NCT00047879 | Glioma | PEG-interferon ... Thalidomide | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Disease Progression and Treatment-induced Alterations in Glioblastoma | NCT02152748 | Brain Tumor | analyze systema... | - | Medical University of Vienna | |
| Magnetic Resonance Elastography in Glioma: Exploring Tumor Stiffness and Adhesion | NCT05990244 | Glioma | Magnetic Resona... Assessment and ... | 18 Years - 80 Years | Shengjing Hospital | |
| Valproic Acid With Temozolomide and Radiation Therapy to Treat Brain Tumors | NCT00302159 | High Grade Glio... Brain Tumors | adjuvant therap... Temozolomide Valproic Acid Radiation thera... | 18 Years - 90 Years | National Institutes of Health Clinical Center (CC) | |
| Effect of NovoTTF-100A Together With Temozolomide in Newly Diagnosed Glioblastoma Multiforme (GBM) | NCT00916409 | Glioblastoma Mu... | NovoTTF-100A de... Temozolomide | 18 Years - | NovoCure Ltd. | |
| XERECEPT® (hCRF) for Patients Requiring Dexamethasone to Treat Edema Associated With Brain Tumors | NCT00088166 | Brain Edema Brain Tumor | hCRF placebo hCRF | 18 Years - | Celtic Pharma Development Services | |
| Memantine for Prevention of Cognitive Late Effects in Pediatric Patients Receiving Cranial Radiation Therapy for Localized Brain Tumors | NCT03194906 | Glioma of Brain Craniopharyngio... Ependymoma Germ Cell Tumor | Memantine Placebo Cognitive Asses... | 6 Years - 21 Years | St. Jude Children's Research Hospital | |
| Ph I Dasatinib + Erlotinib in Recurrent MG | NCT00609999 | Glioblastoma Gliosarcoma | Erlotinib and D... | 18 Years - | Duke University | |
| Neurocognitive Function After Proton Therapy in Children and Adolescents | NCT04066465 | Primary Brain T... | 8 Years - 18 Years | Technische Universität Dresden | ||
| Phase II Study of Temozolomide in Newly Diagnosed Glioblastoma | NCT00365222 | Glioblastoma Gliosarcoma | Temozolomide | 70 Years - | H. Lee Moffitt Cancer Center and Research Institute | |
| Interest of a Weekly Consultation by a Medical Electro Radiology Manipulator (MERM) in Addition to the Follow-up by the Radiotherapist to Improve the Collection of Radio-induced Toxicities in Patients Undergoing Proton Therapy | NCT05404308 | Paramedical Con... Radiotherapy Proton Therapy Brain Tumor | Consultation wi... Consultation wi... | 18 Years - | Centre Francois Baclesse | |
| Record Voxel Rate Nonlinear Optical Microscope to Unravel Brain Connectome and Signaling | NCT05943262 | Brain Tumor Brain Cancer | mesoscale nonli... | 20 Years - | National Taiwan University Hospital | |
| Tumor Related Epilepsy | NCT02639325 | Epilepsy Cancer Brain Neoplasm | 8 Years - 99 Years | National Institutes of Health Clinical Center (CC) | ||
| Efficacy and Safety of AP 12009 in Patients With Recurrent or Refractory Anaplastic Astrocytoma or Secondary Glioblastoma | NCT00761280 | Anaplastic Astr... Glioblastoma | trabedersen temozolomide Drug delivery s... Placement of Dr... carmustine lomustine | 18 Years - 70 Years | Isarna Therapeutics GmbH | |
| Effect of Propofol-Dexmedetomidine on Cerebral Oxygenation and Metabolism During Brain Tumor Resection | NCT02575521 | Brain Tumor Surgery | Propofol-Dexmed... Sevoflurane gro... | 20 Years - 60 Years | Mansoura University | |
| Upright Open MRI for Brain Imaging in Children - a Pilot Study | NCT06257498 | Brain Tumor | MRI scan | 5 Years - 10 Years | Nottingham University Hospitals NHS Trust | |
| Sonography-guided Resection of Brain Mass Lesions | NCT05484245 | Tumor, Brain Arteriovenous M... Cavernoma Intracerebral H... | Sonography | 18 Years - 100 Years | Sklifosovsky Institute of Emergency Care | |
| Convection Enhanced Localized Administration of PRX321 With Real-time Imaging for Therapy of Recurrent Glioblastoma (CLARITY-1) | NCT00797940 | Glioblastoma Mu... | IL-4PE | 18 Years - | Protox Inc. | |
| Intraoperative MRI-guidance in Frameless Stereotactic Biopsies | NCT01779219 | Primary Brain T... | iMRI-guided bra... Stereotactic fr... | 18 Years - | Wroclaw Medical University | |
| Methotrexate Infusion Into Fourth Ventricle in Children With Recurrent Malignant Fourth Ventricular Brain Tumors | NCT02458339 | Brain Tumor, Re... Malignant Neopl... | Ommaya Reservoi... Methotrexate | 1 Year - 21 Years | The University of Texas Health Science Center, Houston | |
| Bevacizumab With or Without Surgery for Adult Glioblastomas | NCT01413438 | Glioblastoma Brain Neoplasm | Craniotomy | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Carboplatin and Bevacizumab for Recurrent Ependymoma | NCT01295944 | Ependymoma Anaplastic Epen... | Carboplatin Bevacizumab | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| A Study of Motexafin Gadolinium and Temozolomide for the Treatment of Malignant Gliomas | NCT00080054 | Glioma Glioblastoma Astrocytoma Oligodendroglio... Brain Neoplasm | Motexafin Gadol... | 18 Years - | Pharmacyclics LLC. | |
| Can we Use Resting-state fMRI and CSD Fiber Tractography for Presurgical Mapping? | NCT06040580 | Brain Tumor Brain Pathology Epilepsy Vascular Malfor... | - | Universitaire Ziekenhuizen KU Leuven | ||
| Dynamic Decompressive Craniotomy | NCT05051488 | Brain Edema TBI (Traumatic ... Stroke, Acute Cerebral Hemorr... Brain Tumor | Dynamic craniot... Dynamic craniot... | 18 Years - | NeuroVention, LLC | |
| Temodar (Temozolomide), Bevacizumab, Lithium and Radiation for High Grade Glioma | NCT01105702 | Brain Cancer | Temozolomide Bevacizumab Lithium Carbona... Radiation | 18 Years - | NYU Langone Health | |
| Convection-Enhanced Delivery (CED) of MDNA55 in Adults With Recurrent or Progressive Glioblastoma | NCT02858895 | Glioblastoma Grade IV Astroc... Glioblastoma Mu... Grade IV Glioma | MDNA55 | 18 Years - | Medicenna Therapeutics, Inc. | |
| PatientSpot Formerly Known as ArthritisPower | NCT03840928 | Rheumatoid Arth... Ankylosing Spon... Fibromyalgia Gout Crohn Disease Juvenile Idiopa... Lupus Erythemat... Myositis Osteoarthritis Osteoporosis Psoriasis Psoriatic Arthr... Scleroderma Dermatomyositis Inflammatory Bo... Polymyositis Axial Spondyloa... Diffuse Idiopat... Polymyalgia Rhe... Giant Cell Arte... Temporal Arteri... Wegener Relapsing Polyc... Undifferentiate... Spinal Cord Inj... Alzheimer Disea... Amyotrophic Lat... Ataxia Bell Palsy Brain Tumor Cerebral Aneury... Epilepsy Guillain-Barre ... Headache Head Injury Hydrocephalus Lumbar Disc Dis... Meningitis Multiple Sclero... Muscular Dystro... Neurocutaneous ... Parkinson Disea... Stroke Cluster Headach... Tension-Type He... Chronic Obstruc... Asthma Lung Cancer Cystic Fibrosis Sleep Apnea Eczema Alopecia Chronic Inflamm... Unstable Angina Heart Attack Heart Failure Arrythmia Valve Heart Dis... High Blood Pres... Congenital Hear... Peripheral Arte... Diabetes Chronic Liver D... Obesity | 19 Years - | Global Healthy Living Foundation | ||
| The Effects of Using Different Anesthetics on the Prognosis of Primary Tumors and Its Mechanism of Action | NCT05926336 | Lung Cancer Brain Tumor Liver Cancer Ovarian Cancer | Propofol Sevoflurane | 20 Years - 80 Years | Kaohsiung Medical University Chung-Ho Memorial Hospital | |
| Risk Factors of Complications Regarding Patients Undergoing Brain Tumour Neuro-surgery (Cranioscore). | NCT01801813 | Neuro-surgery Brain Tumor Post-operative ... Neuro-ICU Stay | Collecting pre-... | 15 Years - 85 Years | Nantes University Hospital | |
| Ph. 2 Sorafenib + Protracted Temozolomide in Recurrent GBM | NCT00597493 | Recurrent Gliob... | Sorafenib and T... | 18 Years - | Duke University | |
| ExAblate (Magnetic Resonance-guided Focused Ultrasound Surgery) Treatment of Brain Tumors | NCT01473485 | Glioma Metastatic Brai... | ExAblate Transc... | 18 Years - 75 Years | InSightec | |
| Phenylbutyrate to Treat Children With Progressive or Recurrent Brain Tumors | NCT00006450 | Brain Tumor | Phenylbutyrate | - | National Institutes of Health Clinical Center (CC) | |
| Dual Perfusion Imaging for Characterizing Vascular Architecture of Brain Lesions | NCT05358340 | Brain Tumor Brain Metastase... | Dynamic suscept... | 18 Years - | University Health Network, Toronto | |
| CONVIVO System to Discriminate Healthy Tissues vs Tumor Tissues During Brain Tumor Resection | NCT05247749 | Brain Tumor | CONVIVO Confoca... | 18 Years - | Stanford University | |
| Tracing Brain Tumors Through Deep Time | NCT06381531 | Brain Tumor Oncology | Imaging with CT... | - | Tata Memorial Centre | |
| A Study of BXQ-350 in Children and Young Adults With Relapsed Solid Tumors | NCT03967093 | Neoplasms | BXQ-350 | 1 Year - 30 Years | Bexion Pharmaceuticals, Inc. | |
| Ketogenic Diet With Radiation and Chemotherapy for Newly Diagnosed Glioblastoma | NCT02046187 | Glioblastoma (G... | Ketogenic Diet Radiation thera... Temozolomide | 18 Years - 80 Years | St. Joseph's Hospital and Medical Center, Phoenix | |
| Post-approval Study of NovoTTF-100A in Recurrent GBM Patients | NCT01756729 | Recurrent Gliob... | NovoTTF-100A | 22 Years - | NovoCure Ltd. | |
| Vaccination With Dendritic Cells Loaded With Brain Tumor Stem Cells for Progressive Malignant Brain Tumor | NCT01171469 | Brain Tumor Glioblastoma Medulloblastoma Ependymoma Anaplastic Astr... | Dendritic Cells Imiquimod | - | Masonic Cancer Center, University of Minnesota | |
| HUMC 1612: Optune NovoTTF-200A System | NCT03128047 | High Grade Glio... Ependymoma | Optune NovoTTF-... | 5 Years - 21 Years | Hackensack Meridian Health | |
| Cytokine Microdialysis for Real-Time Immune Monitoring in Glioblastoma Patients Undergoing Checkpoint Blockade | NCT03493932 | Glioblastoma | Nivolumab BMS-986016 | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Ph I 5-day Temozolomide + O6-BG in Treatment of Pts w Recurrent / Progressive GBM | NCT00612989 | Glioblastoma Gliosarcoma | Temodar and O6-... | 18 Years - | Duke University | |
| The Etiology and Progression of Brain Tumors | NCT01811524 | Brain Tumor Glioma Meningioma | 1 Month - 85 Years | Tampere University Hospital | ||
| Biomarker Analysis of Central Nervous System Tumors | NCT02692898 | Central Nervous... Primary Brain N... Neoplasms, Brai... Cancer of the B... Brain Cancer | - 99 Years | National Institutes of Health Clinical Center (CC) | ||
| Effect of Acupuncture on Inflammation and Immune Function After Craniotomy | NCT02761096 | Unruptured Cere... Hemifacial Spas... Brain Tumor | acupuncture conventional tr... | 18 Years - | Kyunghee University Medical Center | |
| Radiosurgery Dose Reduction for Brain Metastases on Immunotherapy (RADREMI): A Prospective Pilot Study | NCT04047602 | Brain Tumor Brain Metastase... Brain Cancer | Reduced Dose SR... | 18 Years - | Indiana University | |
| Phase II Randomized Study of Stereotactic Radiosurgery Plus Fractionated Whole-Brain Radiotherapy Vs Fractionated Whole-Brain Radiotherapy Alone for Multiple Primary or Metastatic Brain Tumors | NCT00004659 | Brain Neoplasms | irradiation radiosurgery | 0 Years - | Office of Rare Diseases (ORD) | |
| Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed Glioblastoma | NCT01480479 | Glioblastoma Small Cell Glio... Giant Cell Glio... Gliosarcoma Glioblastoma Wi... | Rindopepimut (C... Temozolomide KLH | 18 Years - | Celldex Therapeutics | |
| ESWT for Shoulder Pain in Patients With Brain Damage | NCT04320108 | Brain Damage, H... Stroke Brain Tumor ICH | Extracorporeal ... | 20 Years - | Bundang CHA Hospital | |
| Systematic Light Exposure in Pediatric Brain Tumor Survivors | NCT05340881 | Brain Tumor | Bright Light Ex... Dim Light Expos... Cognitive Asses... | 10 Years - 18 Years | Baylor College of Medicine | |
| Dose Escalation Study to Determine the Safety of IFN-Beta Gene Transfer in the Treatment of Grade III & Grade IV Gliomas | NCT00031083 | Glioblastoma Mu... Anaplastic Astr... Oligoastrocytom... Gliosarcoma | Interferon-beta | 18 Years - | Biogen | |
| Magnetic Resonance (MR) Imaging to Determine High Risk Areas in Patients With Malignant Gliomas and to Design Potential Radiation Plans and to Examine Metabolite Changes in Gliomas and Other Solid Tumors | NCT00870129 | Brain Cancer Glioma | MRI and advance... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Trial Evaluating an Enhanced Physical Activity Intervention to Improve Cognitive Late Effects in Children Treated With Cranial Radiation for Brain Tumors | NCT02153957 | Brain Tumor | Physical Activi... | 8 Years - | National Institutes of Health Clinical Center (CC) | |
| Confocal Laser Endomicroscopy for Brain Tumors | NCT04280952 | Brain Tumor Surgery Convivo System Laser Endomicro... | CONVIVO | 18 Years - | Insel Gruppe AG, University Hospital Bern | |
| Comparing Cosmetic Outcomes: Endoscopic vs. Conventional Craniotomy for Frontal Skull Base Lesions | NCT06417658 | Brain Tumor | Endoscopic Supr... Conventional Fr... | 25 Years - 65 Years | University of Health Sciences Lahore | |
| MRI-Guided LITT for Treatment Metastatic Brain Tumors | NCT01736722 | Brain Tumor | Visualase® | 19 Years - 75 Years | The Methodist Hospital Research Institute | |
| Safety and Feasibility of the Infinity Catheter for Radial Access | NCT04553549 | Brain Tumor Stroke, Acute Brain Aneurysm Intracranial Ar... Carotid Stenosi... Cavernous Sinus... | Transradial app... | 18 Years - | Rutgers, The State University of New Jersey | |
| High Resolution Magnetic Resonance Imaging in Patients With Brain Tumors | NCT02035852 | Brain Tumor | MRI | 18 Years - | University of Texas Southwestern Medical Center | |
| Record Voxel Rate Nonlinear Optical Microscope to Unravel Brain Connectome and Signaling | NCT05943262 | Brain Tumor Brain Cancer | mesoscale nonli... | 20 Years - | National Taiwan University Hospital | |
| SPECTAbrain: Screening Patients With Brain Tumors for Efficient Clinical Trial Access | NCT02307604 | Brain Neoplasms | Tumour markers ... | 18 Years - | European Organisation for Research and Treatment of Cancer - EORTC | |
| Cerebral Blood Circulation in Patients With Posterior Fossa Brain Tumor | NCT01476670 | Brain Tumor | Monitoring | 18 Years - 60 Years | All India Institute of Medical Sciences, New Delhi | |
| Rare CNS Tumors Outcomes &Risk | NCT03251989 | High Grade Meni... Ependymoma Medulloblastoma PNET Primary CNS Sar... | 18 Years - | National Institutes of Health Clinical Center (CC) | ||
| Carboplatin, Vincristine, and Temozolomide in Treating Children With Progressive and/or Symptomatic Low-Grade Glioma | NCT00077207 | Brain Tumor Central Nervous... | carboplatin temozolomide vincristine sul... | - 10 Years | Children's Oncology Group | |
| Developing Interview Questions to Estimate Workplace Exposure to Electric and Magnetic Fields | NCT00340054 | Brain and Centr... | questionnaire a... study of high r... | 18 Years - 65 Years | National Institutes of Health Clinical Center (CC) | |
| Fluorescence Detection of Adult Primary Central Nervous System Tumors With Tozuleristide and the Canvas System | NCT04743310 | Central Nervous... | tozuleristide Canvas imaging ... Surgical resect... | 18 Years - | Cedars-Sinai Medical Center | |
| Bevacizumab for Recurrent Malignant Glioma | NCT00271609 | Recurrent High-... Malignant Gliom... | Bevacizumab | 18 Years - | National Institutes of Health Clinical Center (CC) |
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