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Brief Title: Motor-cognitive Training Effects on Cognition in Breast Cancer Survivors: the BRAINonFIT Study (BRAINonFIT).
Official Title: Motor-cognitive Training Effects on Cancer-related Cognitive Impairment and Muscle-brain Crosstalk Biomarkers in Breast Cancer Survivors: the BRAINonFIT Study
Study ID: NCT06073717
Brief Summary: The goal of this interventional study is to assess the effects of either physical exercise program or combined with cognitive training (dual motor and cognitive training program) on breast cancer survivors. The main questions it aims to answer are: * Analyze the effectiveness of a supervised dual-task training program or a physical exercise program on the executive functions of the participants. * Evaluate the impact of both interventions on physical function, emotional aspects, and important biomarkers related to muscle-brain crosstalk. Participants will perform a 20-week supervised and controlled program, three times a week, along with weekly calorie and step challenges. Researchers will compare the dual-task training group, with the physical exercise group, and with a control group, which will perform the guideline recommendations of physical activity (non-supervised) to see how these intervention approaches can impact cognitive functions, physical functions, emotional aspects, and biomarkers related to muscle-brain crosstalk. Assessments will take place at three-time points: at baseline, after the intervention (20 weeks post-baseline) and after a 12-week follow-up period (32 weeks post-baseline).
Detailed Description:
Minimum Age: 25 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
SADUS - Servicio de Actividades Deportivas de la Universidad de Sevilla, Sevilla, , Spain
Laboratorio de Ciencias del Deporte, Sevilla, , Spain
Oncoavanze, Sevilla, , Spain
Name: Matilde Mora Fernández, PhD
Affiliation: University of Seville
Role: STUDY_DIRECTOR
Name: Luis Carrasco Páez, PhD
Affiliation: University of Seville
Role: STUDY_DIRECTOR
Name: Jesús Orellana Jaén
Affiliation: University of Seville
Role: PRINCIPAL_INVESTIGATOR