Spots Global Cancer Trial Database for Brown Seaweed as a Breast Cancer Preventive

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Trial Identification

Brief Title: Brown Seaweed as a Breast Cancer Preventive

Official Title: Brown Seaweed as a Breast Cancer Preventive

Study ID: NCT01204957

Conditions

Breast Cancer

Interventions

Seaweed and Soy Protein

Placebo and Soy Protein

Study Description

Brief Summary: Japanese postmenopausal women in Japan have about one ninth the rate of American postmenopausal women. Rates of breast cancer double even after just ten years among Japanese women who migrate to the US. Diet is thought to be an important factor, and the investigators were interested in whether dietary seaweed, with and without soy supplements, could influence known biomarkers of breast cancer risk in American women.

Detailed Description: 33 healthy postmenopausal women were randomized to 6 wk seaweed then 1 wk seaweed plus soy or 6 wk placebo then 1 wk placebo plus soy. Blood and urine samples were collected at the end of each treatment period and analyzed for estrogen, homocysteine, antioxidants, insulin-like growth factors and thyroid hormones. Urine was analyzed for phytoestrogens and iodine.